... Radiation therapy for pancreaticcancer Radiation therapy uses high-energy x-rays (or particles) to kill cancer cells. It can be helpful in treating exocrine pancreatic cancer. Pancreatic neuroendocrine ... of cancer, as well as some other diseases. Can pancreaticcancer be found early? One reason for the often poor outlook for people with exocrine pancreaticcancer is that very few of these cancers ... about what causes pancreatic cancer. Some specific DNA abnormalities recently discovered in pancreaticcancer are discussed in the section, “What's new in pancreaticcancer research and...
... co-expressed microRNAs in cancer cells. In a recent study, using five datasets of aberrantly expressed microRNAs in pancreatic and other cancers (breast cancer, colon cancer, lung cancer and lymphoma) ... pancreatic cancer. Palladin is most probably a proto-oncogene (Pogue-Geile et al., 2006). 2.3.1 Familial pancreaticcancer associated PALLD gene (MIM 164757) Few families with isolated pancreaticcancer ... 4.2.1 Familial pancreaticcancer associated PALB2 Germline mutations in PALB2 have been identified in approximately 1-2% of familial breast cancer and 3-4% of familial pancreaticcancer cases...
... A.& Patel, A.V.; PancreaticCancer Cohort Consortium (PanScan) (2010). Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the PancreaticCancer Cohort Consortium ... cycleregulatoryproteins,glycans,galectins,p53,toll‐likereceptors,Grb7andtelomerasein pancreatic cancer fordrugdevelopment.Book 2 covers pancreaticcancer risk factors, treatment and clinical procedures. Itprovides an outline of pancreaticcancer ... alters the expression profiles of microRNAS in human pancreaticcancer cell. Mol. Cancer Ther 7:464-473. Epigenetics and Pancreatic Cancer: The Role of Nutrigenomics 23 modification...
... 2(2) Pancreaticcancer is one of the few cancers 3for which survival has not improved substantially 4over the past 40 years. As a result, in 2003, pan-5creatic cancer surpassed prostate cancer ... IHcreatic cancer are increasing while death rates for all 1cancers combined, including the 4 most common 2cancers (prostate, breast, lung, and colorectal), con-3tinue to decline. 4(6) Pancreaticcancer ... awards) funding in pancreaticcancer 17decreased by 15 percent from 2008 to 2009, a de-18cline larger than that experienced by any of the 19other leading cancers. Pancreaticcancer trainees 20were...
... purposes)Background Pancreatic cancer is one of the most aggressive and lethalcancers known today, with a 5-year survival of only 4%. In2008, pancreaticcancer was the fourth-leading cause of cancer- related ... [4]. Besides pancreatic cancer, gemcitabine is also used for the treat-ment of various other carcinomas including non-smallcell lung cancer [5], ovarian cancer [6] and breast cancer [7]. Due ... damage response in pancreatic cancer cells. Mol Cancer Ther 2009, 8:45-54.44. Giroux V, Iovanna J, Dagorn JC: Probing the human kinome forkinases involved in pancreaticcancer cell survival...
... of pancreatic cancer patients, we investigated whether a panel of tumor mark-ers could diagnose the presence of pancreaticcancer moreaccurately than the current standard tumor marker for pancreatic ... recurrent breast cancer. Eur J Cancer 1995, 31A:1437-1442.14. Cintin C, Johansen JS, Christensen IJ, Price PA, Sorensen S, NielsenHJ: Serum YKL-40 and colorectal cancer. Br J Cancer 1999,79:1494-1499.15. ... panels for the diagnosis of pancreatic cancer, recent work using the LabMAP technol-ogy platform identified a panel of cytokines in plasmathat can detect pancreaticcancer with higher specificitythan...
... drugs in gastric cancer cell lines. Cancer Lett 2004; 214:215-24.18. Cortés-Funes H, Rivera F, Alés I, et al. Phase II of trastuzumab and cisplatin in patients (pts) with advanced gastric cancer ... factor receptor 2 (HER2)-positive advanced gastriccancer (GC). J Clin Oncol 2009; 27:18s(aLBA4509).Connection 2010 |29Treatment Options for Gastric Cancer Localized diseaseAdvanced diseasePreoperative ... and targeted therapies for GC, focusing on trastuzumab. Key Words: Gastric Cancer, HER2, TrastuzumabIntroduction Gastric cancer (GC) treatment and prognosis vary in different regions of the...
... determinants of gastriccancer in south Louisiana inhabitants. J Natl Cancer Inst 1985; 75: 645-65432 Kono S, Ikeda M, Tokudome S, Kuratsune M. A case-control study of gastriccancer and diet ... study on stomach cancer in Germany. Int J Cancer 1991; 47: 858-86450 D’Avanzo B, La Vecchia C, Franceschi S. Alcohol consump-tion and the risk of gastric cancer. Nutr Cancer 1994; 22: ... Oliver W. A case-control study of gastriccancer in Venezuela. Int J Cancer 2001 93: 417-42352 Ye WM, Yi YN, Luo RX, Zhou TS, Lin RT, Chen GD. Diet and gastric cancer: a casecontrol study in...
... in gastriccancer cells.PI3K/Akt is involved in the activation of P-gp byPrPCin gastric cancer To further investigate the underlying mechanism ofPI3K/Akt-mediated PrPC-induced gastriccancer ... protein.Table 1. IC50values (lgÆmL)1) for anticancer drugs for gastriccancer cells. Survival rates of gastriccancer cells treated with anticancerdrugs were evaluated by the MTT assay as ... induced by PrPCin gastriccancer cells.The mechanism underlying PI3K/Akt-mediatedPrPC-induced MDR in gastriccancer was further inves-tigated. PrPC-transfected gastriccancer cell lines...
... Oesophageal and gastric cancers occur mainly in people over 55 years of age. Male sex is a risk factor for squamous cancer of the oesophagus and for oesophagogastric junction cancer. Deprivation ... oesophageal cancer. CSubsternal bypass for oesophageal cancer should not be performed with palliative intentDPalliative gastrectomy should be avoided in patients with gastric cancer who have ... is a risk factor for development of squamous cancer of the oesophagus and for gastric cancer. Tobacco smoking increases the risk of squamous cancer of the oesophagus approximately nine...