... an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines Genes Dev 15 , 14 19 14 26, doi :10 .11 01/ gad.8885 01 Ip YT & Davis RJ (19 98) Signal transduction ... (2000) Sequencing of oxidized methionine-containing peptides for protein identification Rapid Commun Mass Spectrom 14 , 2080–20 81, doi: 10 .10 02 /10 97-02 31( 200 011 15 )14 : 213.0.CO;2-P ... a locus of flexibility in a mitogen-activated protein kinase signaling network Science 297, 10 18 10 23, doi :10 .11 26/science .10 68873297 ⁄ 5583 ⁄ 10 18 [pii] 11 Hornberg JJ, Bruggeman FJ, Binder B,...
Ngày tải lên: 16/02/2014, 14:20
... solani pisi cutinase Biochimie 82 :10 15 10 21 Egmond MR, Van Bemmel CJ 19 97 Impact of structural information on understanding lipolytic function Meth Enzymol 284 :11 9 12 9 El-Zawahry MM, Ibrahim NA, ... temperatures and on blends of cotton/polyester The most recent introduction of a new class of enzyme into detergent formulation is the addition of a mannanase This enzyme helps removal of various ... washed out and often result in a greasy feel, the softness-enhancing effects of cellulases are washproof and non-greasy Optimization of biofinishing processes has been an important area of research...
Ngày tải lên: 06/08/2013, 21:06
Tài liệu Đề tài "Boundary behavior for groups of subexponential growth " docx
... Dln(ln (n) )n ln (n) f (n) ≤ exp for any sufficiently large n Proof Note that C f (n) ≤ C nC max +n + n n1 C≤ (1 2C/ln (n) )n f (ni ) + exp i =1 C ≤ n2 C f (ni ) + exp max +n + n n1 C≤ (1 2C/ln (n) )n i =1 ... ln(ln (n) )n ln (n) F ln(ln (n) )n ln (n) for any sufficiently large n Note that exp(x) + exp(y) ≤ exp(max(x, y)), and hence C f (n) ≤ n2 C max ln max +n + n n1 C≤ (1 2C/ln (n) )n f (ni ) , i =1 F ln(ln (n) )n ... ln(ln (n) )n ln (n) C = n2 C max max +n + n n1 C≤ (1 2C/ln (n) )n ln(f (ni )) , i =1 F ln(ln (n) )n ln (n) 12 04 ANNA ERSCHLER Put g (n) = ln(f (n) This function satisfies C g (n) ≤ 2Cln (n) + max for any sufficiently...
Ngày tải lên: 14/02/2014, 17:20
Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... N- glycans of GAT1, N- glycosylation processing of NNN was inhibited by 1- deoxymannojirimycin (dMM) Inhibition by dMM leads to the formation of NNN molecules containing N- glycans of oligomannosidic ... contains only N- glycans of the mannosidic type The 210 kDa band may represent a dimeric form or a protein aggregate In addition, inhibition of N- glycosylation processing of NNN by 1- deoxymannojirimycin ... treatment with dMM (1 mm) for 72 h, the amount of plasma membrane NNN containing mannosidic N- glycans was in the same range as that of NNN containing mature complex N- glycans without treatment with...
Ngày tải lên: 19/02/2014, 17:20
Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States pdf
... Guidelines: Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1Infected Women for Maternal ... School of Nursing, University of Medicine and Dentistry of New Jersey, Newark, NJ François-Xavier Bagnoud Center, School of Nursing, University of Medicine and Dentistry of New Jersey, Newark, NJ ... 2002;359(9 313 ) :11 78 -11 86 Available at http://www.ncbi.nlm.nih.gov/pubmed /11 955535 Recommendations for Use of Antiretroviral Drugs in Pregnant HIV -1- Infected Women for Maternal Health and Interventions...
Ngày tải lên: 05/03/2014, 13:20
Báo cáo khoa học: Optimization of P1–P3 groups in symmetric and asymmetric HIV-1 protease inhibitors pptx
... 79.2 1. 86 1. 80 2.40–2.30 2.07–2.00 1. 87 1. 81 1.87 1. 81 1.87 1. 81 2 .18 –2 .10 2.07–2.00 1. 97 1. 90 24.6 1. 81 19.0 21. 8 16 77 24.0–2.30 18 .1 20.0 16 62 24.6–2. 01 18.0 20.3 16 47 27.9 1. 81 18.8 222.4 16 97 ... 15 28. 61 1572 .11 15 51. 03 11 10 10 11 11 12 39 52 52 48 51 52 53 47 61 0.90 0.20 0 .13 1. 40 0 .10 4.40 1. 20 0 .10 0.92 Fig Comparison between the 3D structures of our compound and compound L-700, 417 (in ... 46.58 1. 81 92684 216 87 97.2 11 .2 80.5 51. 1 58 .12 86 .11 46 .11 2 .10 35374 13 120 93 .1 7.5 77 .1 63 .1 58.48 86.67 46.52 2.00 44926 15 612 92.9 11 .6 72.5 61. 0 58.89 86.70 46.70 1. 90 623 91 18784 95.7 8.1...
Ngày tải lên: 08/03/2014, 02:20
Báo cáo " On the set of periods for periodic solusions of some linear differential equations on the multidimensional sphere $S^n$ " docx
Ngày tải lên: 14/03/2014, 13:20
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... pig enzyme is not related to the presence of a negative determinant between residues 19 and 28 in the N- terminal region of the enzyme Switching the N- terminal region between human and pig CPT1B ... and isoleucine by valine at position 31 (B) Carnitine Km values of wild-type CPT1B and mutants (C) IC50 for malonyl-CoA inhibition of wild-type CPT1B and mutants analyzed at carnitine concentrations ... Km for carnitine was obtained by assaying mitochondria in the presence of increasing carnitine concentrations: 50 15 00 lm for pig CPTIB, and 50–2000 lm for human CPTIB Western blot analysis and...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Characterization of N-glycosylation consensus sequences in the Kv3.1 channel pot
... McBain CJ (19 96) Developmental expression and functional characterization of the potassium-channel subunit Kv3.1b in parvalbumin-containing interneurons of the rat hippocampus J Neurosci 16 , 506– 518 ... process, of proteins may influence protein folding, maturation, stability, trafficking, and consequently cell surface expression of functional channels [10 12 ] Cell fractionation results of unglycosylated ... aqueous environment Additionally, they demonstrate that N- glycosylation influences the opening of the voltage-dependent gate of Kv3 .1, suggesting that vacant sites alter the folding and maturation of...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx
... binding to A15 is very strong, with substantial electrostatic and dispersion components indicating a strong hydrogen bond between N9 (D) and N3 (A15) The intrinsic strength of this interaction ... end A15 T8 G9 Formamide end A5 T18 C4 G19 Interaction energy (kJÆmol )1) Correlation component (kJÆmol )1) ) 81. 1 )48.5 2.5 )23.4 )1. 3 )19 .6 )19 .6 )12 .5 10 .9 0.0 )18 .8 )1. 3 )5.4 )14 .6 between N7 (D) ... and O2(T18) for N7 (D), O2(T7) and O2(T17) for N5 (D), and N3 (A15) and Ó FEBS 2002 N2 (G9) for N1 (D) N3 (D) only has one close contact to ˚ N3 (A16) and is 3.59 A away from O2(T8) At the other end...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo khoa học: Differential binding of factor XII and activated factor XII to soluble and immobilized fibronectin – localization of the Hep-1/Fib-1 binding site for activated factor XII pdf
... PJ (19 94) Fibronectin’s III -1 module contains a conformationdependent binding site for the amino-terminal region of fibronectin J Biol Chem 269, 19 183 19 187 10 Oberhauser AF, Badilla-Fernandez ... FXIIa and FN involves a cryptic site in FN Such a binding site has been shown to be also responsible for the interaction of FN with fibrinogen and fibrin [27] Hence, fibrinogen and fibrin inhibited ... concentrations of FXIIa, the binding to FN increased linearly with the concentration of FXIIa, and in parallel with the binding of FXIIa to control wells After subtraction of nonspecific binding...
Ngày tải lên: 30/03/2014, 02:20
Báo cáo khoa học: Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells potx
... with each of the dominant negative forms (N1 7Rac1, N1 7Cdc42 and N1 9RhoA) and the corresponding control vectors, and the cells were incubated in the absence or presence of lM LPA for PAK1 activity ... corresponding to residues 83 14 9 of hPAK1) or L107F mutant of PID [22], pcDNA3 .1 expressing the noncatalytic C-terminal domain of FAK, termed FAK related nonkinase (FRNK) [23], and lipase-inactive ... adhesions upon overexpression in fibroblasts and inhibits FAK-mediated signaling events, the role of endogenously expressed FRNK in focal adhesion signaling is unclear [ 41] To determine the significance...
Ngày tải lên: 30/03/2014, 13:20
neural network for beginners (part 1 of 3) - codeproject
... neuron and another are called synapses Information always leaves a neuron via its axon (see Figure above), and is then transmitted across a synapse to the receiving neuron Neuron Firing Neurons only ... enough, an action potential is then generated The action potential (neuronal spike) then travels down the axon, away from the cell body Figure Neuron Spiking Synapses The connections between one neuron ... it sends - this is the all or nothing spiking described in the biology, see neuron firing section above) also called an activation function The inputs (x1,x2,x3 xm) and connection weights (w1,w2,w3...
Ngày tải lên: 28/04/2014, 10:10
State of Illinois REGIONAL OFFICE OF EDUCATION #1 FINANCIAL AUDIT FOR THE YEAR ENDED JUNE 30, 2009 Performed as Special Assistant Auditors for the Auditor General, State of Illinois_part1 pdf
... remaining fund information of the Regional Office of Education #1, as of June 30, 2009, and the respective changes in financial position, thereof for the year then ended in conformity with accounting ... of expressing an opinion on the effectiveness of the Regional Office of Education #1 's internal control over financial reporting Accordingly, we not express an opinion on the effectiveness of ... principally of inquiries of management regarding the methods of measurement and presentation of the required supplementary information However, we did not audit the information and express no opinion on...
Ngày tải lên: 19/06/2014, 19:20
State of Illinois REGIONAL OFFICE OF EDUCATION #1 FINANCIAL AUDIT FOR THE YEAR ENDED JUNE 30, 2009 Performed as Special Assistant Auditors for the Auditor General, State of Illinois_part2 doc
... Action Plan Finding No 09-2 Condition: The Regional Office of Education #1 does not have sufficient internal controls over the financial reporting process The Regional Office maintains its accounting ... REGIONAL OFFICE OF EDUCATION #1 SCHEDULE OF FINDINGS For the Year Ended June 30, 2009 Section II - Financial Statement Findings FINDING NO 09-2 Repeated from 08-3,07-6 CONTROLS OVER FINANCIAL ... version www.adultpdf.com 12 REGIONAL OFFICE OF EDUCATION #1 CORRECTIVE ACTION PLAN FOR CURRENT-YEAR AUDIT FINDINGS June 30, 2009 Corrective Action Plan Finding No 09-3 Condition: A comparison of...
Ngày tải lên: 19/06/2014, 19:20
State of Illinois REGIONAL OFFICE OF EDUCATION #1 FINANCIAL AUDIT FOR THE YEAR ENDED JUNE 30, 2009 Performed as Special Assistant Auditors for the Auditor General, State of Illinois_part3 pot
... Governmental fund financial statements therefore include a reconciliation between the government-wide statements and the fund financial statements The Statement of Net Assets presents the financial ... appropriate for local governmental units of this type A Basis of Presentation Government-wide Financial Statements - The Statement of Net Assets and the Statement of Activities present financial information ... financial information, contact the Assistant Superintendent of the Regional Office of Education #1, 507 Vermont, Quincy, IL 623 01 This is trial version www.adultpdf.com 19 Basic Financial Statements...
Ngày tải lên: 19/06/2014, 19:20
STATE OF CALIFORNIA ADJUSTMENTS TO REPORTED COSTS Page 1 _part1 potx
... 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 8A -1 Sch As ZZT06244I Plant Operations and Maintenance Plant Operations and Maintenance - Salaries ... Education - Nursing 17 0. 01 Inservice Education - Nursing - Salaries and Wages 17 0.02 Inservice Education - Nursing - Fringe Benefits 16 5.00 16 5. 01 165.02 16 5.03 16 5.04 16 5 .11 16 0.00 16 0. 01 160.02 16 0.04 ... Salaries and Wages Plant Operations and Maintenance - Fringe Benefits Plant Operations and Maintenance - Other - Nonlabor 15 5.00 15 5. 01 155.02 15 5.04 10 5.00 10 5. 01 105.02 10 5.03 10 5.04 65.00 65. 01 65.02...
Ngày tải lên: 20/06/2014, 03:20
STATE OF CALIFORNIA ADJUSTMENTS TO REPORTED COSTS Page 1 _part2 pdf
... 11 .1 (1 of 3) Not Reported Not Reported Not Reported 11 .1 (1 of 3) 11 .1 (1 of 3) 11 .1 (1 of 3) 2 2 10 35 85 85 85 7 7 7 7 7 7 Sch 5.00 10 .00 60.00 65.00 75.00 10 0.00 16 0.00 16 5.00 17 0.00 N/ A N/ A ... expense due to insufficient documentation 42 CFR 413 .20 and 413 .24 / CMS Pub 15 -1, Sections 2300 and 2304 16 5 .11 Administration - Other - Nonlabor 10 5.04 Skilled Nursing Care - Other - Nonlabor ... adjustments 5.04 Plant Operations and Maintenance - Other - Nonlabor To eliminate maintenance supplies expense due to insufficient documentation 42 CFR 413 .20 and 413 .24 / CMS Pub 15 -1, Sections 2300...
Ngày tải lên: 20/06/2014, 03:20
STATE OF CALIFORNIARECLASSIFICATIONS AND/OR ADJUSTMENTS TO REPORTED COSTS Page 1 Provider Number: pot
... 1 4 4 083 083 085 085 085 085 090 090 090 090 095 095 095 095 10 0 10 0 10 0 No 083 No 083 4 12 0 12 0 12 0 12 0 12 5 12 5 11 0 10 5 11 5 10 5 11 5 10 5 2 10 5 11 5 10 2 10 2 10 2 11 5 10 2 11 0 10 1 10 1 3 10 1 11 0 10 1 ... 31, 2009 AUDIT ADJ OSHPD Facility Number: 20 619 0263 Page Schedule 8A-2 4 4 12 6 12 6 12 6 12 6 12 8 12 8 12 8 12 8 13 0 13 0 13 0 13 0 13 5 13 5 13 5 13 5 13 9 13 9 13 9 No 12 5 No 12 5 14 5 15 5 15 5 15 5 4 16 0 16 5 16 5 ... on page 10 .1, column 14 42 CFR 413 .20 and 413 .24 / CMS Pub 15 -1, Sections 2300 and 2304 Explanation of Audit Adjustments MEMORANDUM ADJUSTMENTS EISENHOWER NURSING & CONVALESCENT HOSPITAL JANUARY...
Ngày tải lên: 20/06/2014, 03:20
Báo cáo toán học: " Electrochemical performance of NixCo1-xMoO4 (0 [less than or equal to] x [less than or equal to] 1) nanowire anodes for lithium-ion batteries" pptx
... performance of NixCo1−xMoO4 (0 ≤ x ≤ 1) nanowire anodes for lithium-ion batteries Kyung-Soo Park1, Seung-Deok Seo1, Hyun-Woo Shim1, and Dong-Wan Kim *1 Department of Materials Science and Engineering, ... of Co- and Ni-containing reagents were dissolved in deionized water (80 mL) under constant magnetic stirring; then, the solution was added to an aqueous solution (80 mL) containing 0 .1 M of Na2MoO4·2H2O ... the diameters and lengths of the nanowires tended to decrease with increasing Ni concentration As shown in Figure 1e, the NiMoO4·nH2O nanowires were agglomerated acutely and even formed clusters...
Ngày tải lên: 20/06/2014, 21:20