oxidative stress hypothesis in alzheimers disease a reappraisal
Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot
... 262, 437–447. 9 Costa V & Moradas-Ferreira P (2001) Oxidative stress and signal transduction in Saccharomyces cerevisiae: insights into ageing, apoptosis and diseases. Mol Aspects Med 22, 217–246. 10 ... Veal EA, Findlay VJ, Day AM, Bozonet SM, Evans JM, Quinn J & Morgan BA (2004) A 2-cys peroxire- doxin regulates peroxide-induced oxidation and activa- tion of a stress- activated MAP kinase. Mol ... Izawa S, Inoue Y & Kimura A (1996) Importance of catalase in the adaptive response to hydrogen peroxide: analysis of acatalasaemic Saccharomyces cerevisiae. Biochem J 320, 61–67. 65 Boy-Marcotte...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation ppt
... data [10] suggest that cellular proteins are a likely key target for toxicity mediated by singlet oxygen. Oxidative assault may cause modifica- tions of the side chains of amino acids within a ... 4A, B). Matching the blot with the protein map shows that PDT caused labeling of a- tubulin and b-tubulin (spots 1 and 2). The minor spot 3 probably reflects labeling of a small fraction of actin. The ... Germany). Assessment of dityramine formation caused by PDT Photosensitizers at a final concentration of 10 l M were added to a well of a plastic culture plate containing 1 m M tyramine in NaCl/P i ,...
Ngày tải lên: 23/03/2014, 15:21
finite element simulation and analysis of local stress concentration in polymers with a nonlinear viscoelastic constitutive model
Ngày tải lên: 29/11/2014, 07:00
báo cáo hóa học: " The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer''''s disease" ppt
Ngày tải lên: 19/06/2014, 22:20
Báo cáo khoa học: Oxidative stress induces a reversible flux of cysteine from tissues to blood in vivo in the rat pptx
... of administered inorganic mercury. Drug Metab Dispos 25, 516–523. 51 Shinozuka S, Tanase S & Morino Y (1982) Metabolic consequences of affinity labeling of cystathionase and alanine aminotransferase ... mgặkg )1 intraperi- toneally) was administered 5 h before starting diamide infu- sion, whereas acivicin was administered in two doses (each 10 mgặkg )1 intraperitoneally) 2.5 and 1 h before starting diamide infusion. ... purchased from Charles River Laboratories (Calco, Italy). A double valve (model 617, 20 · 20 mm; Danuso Instruments, Milan, Italy) was implanted in each animal; jugular and femoral veins were cannulated...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential doc
... pre- sented in Fig. 3C suggest increases in cytosolic [Ca 2+ ] in response to CsA and its analogs. Both the intra- cellular Ca 2+ chelator BAPTA and the extracellular Ca 2+ chelator EGTA caused significant ... [Ca 2+ ]by CsA and its analogs. However, mitochondria, involve- ment of P-glycoprotein and inhibition of calcineurin are unlikely to play a role in CsA-induced oxidative stress and disturbed Ca 2+ homeostasis. ... consumption was monitored with sequential addition of succinate, ADP (to induce state III respir- ation) and CsA, until state IV respiration was reached again, when all ADP was converted to ATP. DNP was...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus ppt
... CTAGCTGGTGAAGCAATGTCTCCGCAACATTTGGCGACATGGTCTCATAT 5Â anking reverse GGCCGAGGAGCAGGACTGAGAATTCTTTGCGGTCTTCCTGAAGCTGACCACTGT 3Â anking forward CATTGTTTGAGGCGAATTCGATATCGAGGCTCAGAACCTCCCTGCGCAGACGCG 3Â anking reverse ... GGCCTCCCTAAGCTTCTGGACCTTTTCGCGTGTTGCTTCCGACATAGGAACGAG zeocinpyrG forward GAATTCTCAGTCCTGCTCCTCGGCC zeocinpyrG reverse GATATCGAATTCGCCTCAAACAATG Nested forward GAGACCTAGGAAGCAATGTCTCCGCAACATTTGGCGACATGGTCTCATAT Nested ... CGCTGGCGAACACATTATATGA pes1 E1-C1 reverse ACGAATTACTTGCAGCCGCTT sidD forward ACGCAACCGACTGGTTGTT sidD reverse ATTCGTGCGAGACTCGGAT Calmodulin forward CCGAGTACAAGGAAGCTTTCTC Calmodulin reverse GAATCATCTCGTCGACTTCGTCGTCAGT Aspergillus...
Ngày tải lên: 30/03/2014, 10:20
báo cáo hóa học: " Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis" pptx
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"
... shows activities of AS, AL and arginase in the study. AS and AL activities increased in all the three brain regions significantly in anoxia suggesting an increased utilization of citrulline ... reactive substances and decreased total antioxidant status indicate the presence of oxidative stress in anoxia and reperfusion. The increased arginase and sustained decrease of GS activity in reperfusion ... may also serve as a substrate for glutamate formation and may also provide increased substrate for arginase (50). No significant changes in the activity of arginase in the anoxic group indicate...
Ngày tải lên: 26/10/2012, 09:07
Tài liệu Báo cáo khoa học: The alr2505 (osiS) gene from Anabaena sp. strain PCC7120 encodes a cysteine desulfurase induced by oxidative stress docx
... from Anabaena sp. strain PCC7120 encodes a cysteine desulfurase induced by oxidative stress Marion Ruiz, Azzeddine Bettache, Annick Janicki, Daniel Vinella, Cheng-Cai Zhang and Amel Latifi Aix-Marseille ... AAC TTC GC Reverse: GCC TTG GTG ACA ATT ATG TA alr2505 Forward: GTT GCA ACA CAC CAA TTT CG Reverse: CAA GCA CGG GAA ATT TTA GC OsiS: oxidative stress- induced cysteine desulfurase M. Ruiz et al. 3722 ... Latifi A, Ruiz M, Jeanjean R & Zhang CC (2007) PrxQ -A, a member of the peroxiredoxin Q family, plays a major role in defense against oxidative stress in the cyanobacterium Anabaena sp. strain...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Autosomal-recessive genes in Parkinson’s disease – a common pathway? docx
... Ishikawa A, Nagai H, Sai- to M, Maruyama M, Takahashi T, Ozawa T, Tsuji S & Takahashi H (2000) An autopsy case of autosomal- recessive juvenile parsinsonism with a homozygous exon 4 deletion in ... kinases including casein kinase 1, protein kinase A, protein kinase C [86] and cyclin-dependant kinase 5 [87]. Phos- phorylation of Parkin by CDK5 may regulate its ubiqu- itin-ligase activity and ... ubiquitin pathway in Parkinson’s disease. Nature 395, 451–452. 60 Yokota T, Sugawara K, Ito K, Takahashi R, Ariga H & Mizusawa H (2003) Down regulation of DJ-1 enhances cell death by oxidative stress, ...
Ngày tải lên: 18/02/2014, 14:20
Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf
... employed a mixture of 5mm malate and 25 lm palmitoyl-l-carnitine as oxidative substrates. State 2 respiration (resting) was measured after addition of oxidative substrates, and state 3 respiration after ... expression in female hearts indicates that myocardial glucose metabolism may be increased in parallel. As optimization of glucose metabolism is increasingly highlighted as a therapeutic intervention for ... ischemia-induced and ischemia–reperfusion-induced cardiac damage [7], our data provide a novel mecha- nism for how signaling cascades induce transcriptional pathways to augment glucose-mediated cardioprotec- tion...
Ngày tải lên: 18/02/2014, 16:20