oxidative stress and transforming growth factorβ1induced cardiac fibrosis
Báo cáo y học: "β Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases" potx
... additional factors and/ or cofactors thatsecondarily contribute to their function and that maybecome prevalent in the absence of TGF-β and/ or if TGF-βis dysregulated. The identification and intersection ... theperiphery, and to represent less than 10% of CD4+T cells 67for the induction and/ or expansion of Treg to enhancetheir role in autoimmunity, allergy, and graft rejection.ConclusionInnate and adaptive ... important new evidencedocuments that Treg can be expanded and/ or induced denovo from CD4+CD25–precursor T cells. How, where, and if the size and function of this population can beintentionally...
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Tài liệu OXIDATIVE STRESS AND DISEASES pptx
... orders@intechopen.com Oxidative Stress and Diseases, Edited by Volodymyr Lushchak and Dmytro V. Gospodaryov p. cm. ISBN 978-953-51-0552-7 Oxidative Stress: Cause and Consequence of Diseases ... pathologies and oxidative modification of proteins. Most antioxidant and related enzymes are targets for oxidative modification. Hence, if oxidative stress was primary event, possible oxidative ... and Ortiz-Butron Rocio Chapter 19 Oxidative Stress in Human Autoimmune Joint Diseases 437 Martina Škurlová Chapter 20 Oxidative Stress in Multiple Organ Damage in Hypertension, Diabetes and...
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Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
... Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression inbrown and white adipose tissues. Particle and Fibre Toxicology 2011 8:20.Submit ... (eWAT,rWAT, and iWAT, left), and brown adipose depots (iBAT, and mBAT, right) by real-time PCR.n=8.*P < 0.05 vs. FA.Xu et al. Particle and Fibre Toxicology 2011, 8:20http://www.particleandfibretoxicology.com/content/8/1/20Page ... insulinresistan ce, oxidative stress, alteration of vasomotor tone,vascular and visceral inflammation, adiposity, and atherosclerosis in apolipoprotein E knockout (ApoE-/-)mice and other several...
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Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot
... of RhoA and Rac1 GTPases and their downstram effectorsROCK kinase, LIMK and cofilin, and the concomitantupregulation of a-SMA gene expression [141].TGFb-induced Rho GTPase activation and actinremodeling ... essential for transforming growth factor-beta-mediated stress fiber formation. J Biol Chem 276,15362–15368.159 Engel ME, Datta PK & Moses HL (1998) RhoB isstabilized by transforming growth factor ... & Colicelli J (2008) Integration of transforming growth factor beta and RAS signalingsilences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration.Mol...
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Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot
... AGP2_BOVIN; O77802), and human (AGP1_HUMAN; Q15389 and AGP2_HUMAN; O15123). (iv) Ficolins: ficolin A and B frompig (FICOLA_PIG; L12344 and FICOLB_PIG; L12345), mouse (FICOLA_MOUSE; AB007813 and FICOLB_MOUSE; ... (TECL5A-TACTR; AB024737.1 and TECL5B_TACTR; AB024738.1).(iii) Angiopoietin: angiopoietin 1 and 2 precursors from mouse (AGP1_MOUSE; O08538 and AGP2_MOUSE; O35608), bovine (AGP1_BOVIN;O18920 and AGP2_BOVIN; ... EGF and required for biological activity[77], are also found in the sponge and are highly conservedin domain 2. Likewise, amino acids, which are involved inligand-receptor binding [52] and...
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Báo cáo khoa học: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice pdf
... Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1expression. Mutagenesis 22, 189–194.5 McKillop IH & Schrum LW (2005) Alcohol and livercancer. ... &Pacher P (2005) Role of oxidative- nitrosative stress and downstream pathways in various forms of cardiomyop-athy and heart failure. Curr Vasc Pharmacol 3,221–229.33 Narula J, Pandey P, Arbustini ... evidence indicating that the over-expression of CYP2E1 causes cardiac oxidative stress, myocyte apoptosis and the DCM phenotype.Materials and methodsAnimalsThe a-MHC-cTnTR141Wtransgenic mice...
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Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc
... lipopolysaccharide-inducedtumour necrosis factor-a production by transforming growth factor-b1Tarnjit K. Khera1, Andrew D. Dick1,2 and Lindsay B. Nicholson1,21 Department of Cellular and Molecular Medicine, School of ... anti-inflammatorycytokine transforming growth factor-b1 (TGF-b1) ofthe proinflammatory cytokine TNF-a via the inductionof FXR1 is the focus of this article.TGF-b1, a member of the large transforming growth factor-b ... of interferon-gamma (IFN-gamma), IL-10,IL-12 and transforming growth factor-beta (TGF-beta) mRNA in synovial fluid cells from patients inthe early and late phases of rheumatoid arthritis(RA)....
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Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
... oxidative stress (Fig. 4A,B). Under oxidative stress, partial inhi-bition of PARP activity led to altered growth, suggest-ing that oxidative stress could be leading to cell cyclearrest [22] and ... during oxidative stress- induced growth changes in D. discoideum. Under oxidative stress, the growth curve showed a dose-dependent increase in the lag phase.The log phase was shortened, and this ... transcription by oxi-dative stress. Mol Biol Cell 15, 5659–5669.23 Vohra I (2005) Effect of UV-C irradiation and oxidative stress on Dictyostelium discoideum growth, development and cell death. MPhil...
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Báo cáo khoa học: The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells doc
... effects of BA, ATR and ANT1 siRNA on cell viability and glucose consumption. (A,B) Cell growth curves analyzed bycrystal violet assay in BA and vehicle-treated (A) and in ATR and vehicle-treated ... Scramble- and ANT1 siRNA-transfected U-87-MG cells, 24 and 48 h after transfection. (C) Cell growth curves analyzed by crystal violet assay in nontransfected U87-MG cells, and in Scramble- and ANT1siRNA ... RNAFig. 2. Effect of ANT1 and ANT2-silencing on ADF cells. (A) Cell growth curves analyzed by crystal violet assay in nontransfected ADF cells, and in Scramble- and ANT1 siRNA and ANT2 siRNA ADF-transfected...
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Báo cáo khoa học: Oxidative stress and apoptotic events during thermal stress in the symbiotic sea anemone, Anemonia viridis potx
... apoptosis protein and heat shock proteins [47,48].Caspase-like activity and oxidative stress After the finding of caspase-like activities and aresponse by these enzymes to heat stress, parallel ... stud-ies and supports the occurrence of an oxidative stress period in heat stressed A. viridis [24]. We suggest thatapoptosis induction could be the consequence of theprevious oxidative stress ... underlined.Apoptosis and oxidative stress in bleaching S. Richier et al.4190 FEBS Journal 273 (2006) 41864198 ê 2006 The Authors Journal compilation ê 2006 FEBS Oxidative stress and apoptotic events...
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