... cochlear epithelium, cartilage, bone, bronchi of the lung, cuboidal epithelial lining of the kidney tubules, liver capsule, and smooth muscle of oesophagus and intestine. Table 2 is a summary of the unique distribution of TGFb3 mRNA transcripts and its protein during ... TGFb3 mutations and diseases 1.2.1.13.1 Potential candidate gene for nonsyndromic oral clefts TGFb3 has been proposed as one of the potential candidate genes for non syndromic oral clefts. The strong supporting evidences are derived ... TGFb Subfamily and its isoforms ………………………………………………… 11 Latent TGFb, latent TGFb binding protein, and bone … 11 Perturbation of TGFb signalling in human diseases ………………………………. 13 TGFb3, and expression patterns during early embryogenesis and in adult...
Ngày tải lên: 14/09/2015, 18:03
... assessment and urinalysis was conducted on day 23 or 24 At necropsy, liver, kidney, and heart weights were recorded, and the liver and kidneys were examined histologically Absolute and relative liver ... and the percentage of the oxidative derivative of the monoester and of MIDP at the same doses were, respectively, 25 and 30%, 14 and 26%, and 13 and 13% The data suggest a metabolic scheme comparable ... reduced on pnd and in all treated groups, and also on pnd and at weaning in the high-dose group An unusually high incidence of pup deaths in 4, 2, and litters of the low-, mid-, and highdose groups...
Ngày tải lên: 13/02/2014, 10:20
NTP-CERHR MONOGRAPH ON THE POTENTIAL HUMAN REPRODUCTIVE AND DEVELOPMENTAl EFFECTS OF BISPHENOL A pot
... the incidence of a variety of other ovarian and uterine proliferative lesions and cysts were also reported Replication of these findings and further study of the linkage of early and late occurring ... the rate of metabolism of bisphenol A differs following oral and non -oral administration There is also consensus that fetal and neonatal rats not metabolize Understanding the impact of variations ... estradiol + testosterone), route of administration (subcutaneous versus oral to dams), or other factor such as animal husbandry and housing In mice, exposure of pregnant dams to bisphenol A at an oral dose of 0.010...
Ngày tải lên: 05/03/2014, 16:20
Báo cáo khoa học: In vitro embryonic developmental phosphorylation of the cellular nucleic acid binding protein by cAMP-dependent protein kinase, and its relevance for biochemical activities pdf
... composed of unpaired strands, CNBP, hnRNP K, and additional factors [7] Modulation of the concentrations and ⁄ or the biochemical activities of either CNBP or hnRNP K could influence the ability of ... single-stranded nucleic acids and is able to promote interstrand reannealing of DNA as well as RNA [35,36] hnRNP Al is phosphorylated by CK2 and PKA PKA phosphorylation suppresses the ability of hnRNP ... 10 volumes of NaCl ⁄ Pi, proteins were eluted, and run in 12% (w ⁄ v) SDS ⁄ PAGE Phosphorylation of CNBP was visualized by using a GP-Storage Phosphor Screen and storm scanner and software (Amersham...
Ngày tải lên: 16/03/2014, 12:20
Báo cáo y học: "Primary congenital anomalies of the coronary arteries and relation to atherosclerosis: an angiographic study in Lebanon" doc
... course of anomalous artery was defined according to the guidelines of Yamanaka and Hobbs [11] http://www.cardiothoracicsurgery.org/content/4/1/58 and the "eye -and- dot method" [12] Most of the ... prevalence of different forms of anomalous aortic origins of coronary anomalies and their anatomic variations in a selected adult Lebanese population Methods We reviewed the database of 4650 adult ... from the incorrect coronary sinus of Valsalva [2,7,9,10] Diagnosis and understanding of coronary artery anomalies are important in considering the severity of coronary artery stenosis, particularly...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo khoa hoc:" Vitamin D and oestrogen receptor polymorphisms in developmental dysplasia of the hip and primary protrusio acetabuli – A preliminary study" ppt
... polymorphism at these loci and the presence of DDH and PPA We also explored the effect of genotype on acetabular morphology and severity of the conditions Patients and methods Hypothetically, ... and spans more than 140 kilobases The most widely studied polymorphic regions are the Pvu II and Xba I restriction fragment length polymorphisms in intron and the (TA) n variable number of tandem ... the promoter region of the gene The ESR1 is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription Alternative...
Ngày tải lên: 11/08/2014, 08:21
Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.
... conditional breakfast They often have cereal or porridge, egg and bacon followed by toast and marmalade and coffee and tea or they may just have a toast and marmalade and coffee and tea *Elevenses - ... People often drink a glass of mild and a sandwich 3.1.6 Parts of meal Basically, English meals and meal time are quite clear Even name of courses are also: starter, main course/ meat course and ... eating out and pointing out connoisseur of them Etiquette of eating Looking at the way of cooking, eating of a country, a family, people can assess how the intellectual and culture standard of the...
Ngày tải lên: 15/04/2013, 15:11
A study of semantic and pragmatic features of the adjective warm and its vietnamese equivalents
... review of the research Chapter 3: “Methodology and Procedures” mentions the method and procedures of the research Chapter 4: “Findings and Discussions” is the main frame of need to understand semantics ... hyponym of animal 2.2.1.7 Semantic field The semantic structure of vocabulary of a language can be studied in a precise and systematic way by means of componential analysis of which the theory of ... science of government or governing, especially the governing of a political entity, such as a nation, and the administration and control of its internal and external affairs 3.1 RESEARCH DESIGN AND...
Ngày tải lên: 26/11/2013, 13:21
A contrastive analysis of semantic and pragmatic features of the words denoting birds in english and vietnamese
... teaching and learning of English 3 1.4 RESEARCH QUESTIONS: (1) What are the similarities and differences of semantic features of the WDBs in English and Vietnamese? (2) What are the similarities and ... recognition of the field And the findings of semantic aspects often borrow the WDBs for not only conveying the denotative as well as analysis of pragmatic aspects of these kinds of words will meaning ... behaviour and attitude, intellectual, Thirdly, while the Vietnamese consider the WDB “én” as a evaluative characteristics, diseases and time measurement Through messenger of spring because of the...
Ngày tải lên: 26/11/2013, 13:30
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... characterization of numerous complexes of the human HPRT and several bacterial and protozoan HPRTs have been undertaken [13–17] The structure of human HPRT can be divided into two domains: a core domain and ... domain is mainly built up by residues from the C-terminus and consists of a two-stranded anti-parallel b-sheet composed of b2 and b9 and an a-helix from the C-terminus (Fig 1A) The two subunits ... the base of bound GMP is stacked between Val143 and Phe194 N1, N2 and O6 of the nucleotide form hydrogen bonds to main chain atoms, whereas the side chain of Lys173 interacts with both O6 and N7...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu NEW AND ORIGINAL THEORIES OF THE GREAT PHYSICAL FORCES doc
... theories of the transmission of light and sound; of the production of winds, and sun-spots, and of the method of development and dissemination of heat, are in point of fact, unphilosophical and incomprehensible ... construction of a true philosophy of the physical forces must depend now upon our rightly understanding the modus operandi of the conveyance, and utilization, of these sun-elements, and the workings of ... wasted—Extent of the atmosphere of the spheres—The sun's power overestimated CHAPTER XIII INFLUENCE OF THE FORCES AS CAUSATION OF DISEASE 84 Meteorological influence—Higher appreciation of the source of disease, ...
Ngày tải lên: 17/02/2014, 01:20
Tài liệu STRATIGRAPHY AND AMMONITE FAUNA OF THE VOLGIAN AND BERRIASIAN ROCKS OF EAST GREENLAND ppt
... number of sections through conglomerates, sands and sandstones, and ::::-z; , Sond &sandstone oooo Doggerr Bonded rhole rand , ~ - - @ 50m Fossil locality Altitude 500m Fig Rkebcll map of ... are the "banded beds" of rapidly alternating black shale and yellow sand, assoc,iated with sandstones and conglornerates and yielding Laugeifes Thcsc bcds wcrc rrlappcd b y VISCHER and Mnvxc ... equivalent of thc npper part of t h e Portland Beds of southern England If, with ARKELL (1946, pp 24-28), we place the Portland Beds in the upper part of the Lower Volgian, they, the Laugeitcs Beds and...
Ngày tải lên: 17/02/2014, 20:20
Tài liệu A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco pptx
... variety of computers including obsolete, old, middle-aged and new computers It exists because of the efforts of hundreds of volunteers and donations from people in all walks of life Volunteers and ... that of ardent spirits It does not make men maniacs and demons But that it does undermine the health of thousands; that it creates a nervous irritability, and thus operates on the temper and moral ... moral character of men; that it often creates a thirst for spirituous liquors; that it allures to clubs, and grog-shops, and taverns, and thus helps to make idlers and spendthrifts; and finally,...
Ngày tải lên: 17/02/2014, 22:20
Tài liệu The Dynamic Retention Model for Air Force Officers- New Estimates and Policy Simulations of the Aviator Continuation Pay Program doc
... Theory and Estimates, RAND Corporation, R-3028-AF, 1984, and the extension of the basic DRM to take into account the effect of the availability of multiyear contracts to certain classes of Air ... practitioners and research professionals, and supporting documentation; or deliver preliminary findings All RAND reports undergo rigorous peer review to ensure that they meet high standards for ... policies RAND Project AIR FORCE RAND Project AIR FORCE (PAF), a division of the RAND Corporation, is the U.S Air Force’s federally funded research and development center for studies and analyses...
Ngày tải lên: 17/02/2014, 23:20
Tài liệu Static and Dynamic Analysis of the Internet’s Susceptibility to Faults and Attacks docx
... Fig 10 Dynamic characteristics of the Internet—average degree, creation of nodes and links, and death of nodes and links; (a): mn and me denotes the number of nodes and links added since November, ... characteristics of the Internet; , Ko and DIKo are defined as the average diameter, K, and DIK of the original networks and df , Kf and DIKf denote the diameter, K, and DIK after 10% of the nodes ... about 18% of dead links was due to node deletion and 82% of link deaths occurred without node death dn and de denote the number of nodes and links deleted since November, 1997 The number of internal...
Ngày tải lên: 18/02/2014, 01:20
Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf
... E22K, E22Q and D23N), and the availability of a rapid and simple expression and purification protocol will facilitate large-scale investigations of the molecular determinants of aggregation and fibrillation ... supplied with the enzyme, and contained Aba, Abb and Abc at 40 nm each, and the start and stop primers Abstart and Abstop at 600 nm each, and 200 lm each of dATP, dCTP, dGTP and dTTP The product was ... attenuance at 600 nm (D660 nm) of 3.0–3.1 SDS-PAGE and agarose gel electrophoresis of sonicates of the bacterial cell pellet and the urea extract revealed that the first and second supernatants after...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... of a hinge point at Arg53 that exhibits conspicuous minima of J(0) and J(xN) and a significant maximum of J(0.87xH), and that emerges not only within helix III, but also over a large portion of ... residues and hence does not conflict with the global interpretation of the data With the exclusion of the N-terminal octapeptidyl and C-terminal nonapeptidyl fragments of Glu17, Leu34 and Lys46, ... dynamics of the rat TTF-1 homeodomain Table Mean values and corresponding standard deviations (in parentheses) of S2 (dimensionless) and se (ps) parameters for the secondary structure elements of the...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Molecular modeling and functional characterization of the monomeric primase–polymerase domain from the Sulfolobus solfataricus plasmid pIT3 doc
... plausibly involved in DNA recognition and binding and is positioned left of the active site [14] Rep245 is both capable of de novo synthesis of DNA primers and of elongating them Long DNA extension ... concentration of Rep245 prepared in 10 mm sodium phosphate (pH 7.4) was lm CD spectra were recorded at 60, 70 and 80 °C between 190 and 260 nm with a step increase of 0.2 nm, and a bandwidth of nm Thermal ... side-chains of the first pair of residues, i.e K135 and R148, matched almost exactly; those of the second pair were in close proximity The R148 residue of the Pfu-primase is part of a motif which...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf
... using the purified recombinant protein, the conversion of reagents and products of the exopeptidasecatalyzed hydrolysis of Met1 and cyclization of Gln1 to pyroglutamyl were monitored at different ... first h of the reaction Guanidinium chloride concentration pH 6.2 7.2 8.0 Fig Comparison of the hydrolysis reaction as a function of denaturing agent and pH (A), (B) and (C): (d), (s) and (.) ... to 2.5, 8.0 and 11.5 and the samples were incubated at 37 °C, 50 °C and 70 °C Aliquots were taken at different time-points from each sample and analyzed by MALDI-TOF MS The addition of the protease...
Ngày tải lên: 19/02/2014, 12:20