obtaining the k x 1 vector of risk premia l

... 1. 5** 1. 8** 1. 2 1. 3** 0.5-0.7 1. 7-2.2 1. 1-3.8 1. 2 -1. 3 1. 4 -1. 7 1. 3 -1. 6 1. 4-2.5 0.9 -1. 5 1. 3 -1. 4 74 12 47 1. 6** 7.0** 1. 4 -1. 7 4 .1- 12.0 23 23 1. 0 0.8 -1. 4 0.7 0.4 -1. 1 17 27 24 32 0.7* 0.8 0.5-0.9 0.6 -1. 1 ... of filtering/blocking software Parent-use of AOL Parental Controls Youth-knowledge of home use of filtering/blocking software –2 log likelihood Chi-square (df ) R2 (Cox & Snell) R2 (Nagelkerke) ... = 1, 047) Estimate Interval 21 42 77 14 20 44 49 75 14 20 0.4** 0.8 1. 1 1. 0 1. 0 0.3-0.5 0.6 -1. 0 0.9 -1. 5 0.7 -1. 4 0.7 -1. 3 60 52 1. 4* 1. 1 -1. 7 57 18 53 14 1. 2 1. 3 0.9 -1. 5 1. 0 -1. 9 38 47 47 41 0.7* 1. 3...

Ngày tải lên: 29/03/2014, 19:20

... high risk of death and others at low risk of death Perhaps if there had been an a priori assignment of clinical assessment of risk of death in the PROWESS trial, the effect of rhAPC in these ... Critical Care Vol 10 No Dellinger use of rhAPC in patients at high risk of death and required a repeat trial in patients at low risk of death The specified intent of the ADDRESS trial was to enroll ... identifying risk of death prospectively: a clinical assessment of risk of death or APACHE II scoring? The PROWESS trial had no inclusion criteria related to clinical assessment of risk of death...

Ngày tải lên: 12/08/2014, 23:21

... affected by the hormone status of the patient Most likely, β-estradiol acts by modifying intracellular levels of the active form of D4T through mechanisms which may include controlling drug influx or ... efflux or, more likely, controlling the phosphorylation steps which lead to the D4T-TTP active form of D4T [11 ,12 ] Thus, monitoring of β-estradiol levels, which vary during pregnancy, menstrual ... charcoal dextran stripped FBS (Invitrogen, CA), mM glutamine, 10 0 unit of penicillin per ml, 10 0 ug of streptomycin per ml, 10 mM HEPES), and half-maximal units per ml of human Interleukin-2 (Roche,...

Ngày tải lên: 13/08/2014, 05:21

... well as at an IT level; whereas mobile, cloud [and risks associated with other emergent trends] are still often looked at only as technology risks [not business risks]” Therefore, they not always ... under-estimating the growing complexity of technology 17 18 An expanding network of risk and opportunity: How UK SMEs are under-estimating the growing complexity of technology An expanding network of risk and ... years to come, these figures are still alarmingly low overall Against the fast-paced mobile backdrop, the explosion of a mobile-enabled marketplace and the dramatic adoption curve of devices, better...

Ngày tải lên: 04/12/2015, 00:03

... yi ∈ L, g (L) for every ≤ i ≤ k + (2.2) It follows from (2.2) and (H3 ) that g (L) = f g (L) ,L ≥ xk+2 = f xk +1 , y1 ≥ f L, g (L) = L, g (L) = f g (L) ,L ≥ yk+2 = f yk +1 ,x1 ≥ f L, g (L) = L Inductively, ... 1. 1 is proven Examples To illustrate the applicability of Theorem 1. 1, we present the following examples Example 3 .1 Consider equation p + xn , + y n k p + yn , yn +1 = + x n k xn +1 = n = 0 ,1, ... = f xi 1 , yi 1 k > f xi 1 , yi 1 k + ≥ a, yi = f yi 1 ,xi 1 k > f yi 1 ,xi 1 k + ≥ a, for every ≤ i ≤ k + (2 .1) Since limx→a+ g (x) = +∞, there exists L ∈ (a,+∞) with L < g (L) such that xi ,...

Ngày tải lên: 22/06/2014, 22:20

... st Saturday, March 29th 2008 Unit 14 WONDERS OF THE WORLD (Lesson 1) GETTING STARTED Match the names of these famous world landmarks to the correct pictures The Pyramids Stonehenge a) b) Sydney ... Golden 7) right 8) was Saturday, March 29th 2008 Unit 14 WONDERS OF THE WORLD (Lesson 1) LISTEN AND READ Language games Ask Yes/ No questions about this place - river/ moutain/ bay/ cave/ lake ... Unit 14 WONDERS OF THE WORLD (Lesson 1) WARM UP: Look at the pictures of famous places in Viet Nam and answer WHAT IS IT? WHERE IS IT? In Fansipan moutain Quang Binh Cai and Ha In In QuangLong...

Ngày tải lên: 22/06/2013, 01:27

... help the big American steel mills In fact, the quotas will help “mini-mills” flourish in the United States Those small domestic mills will take more business from the big Americal steel mills ... reduction in the amount of private-plane traffic would reduce the risk of midair collision around the centrally located airports Which of the following, if true, would most strengthen the conclusion ... damage to the lungs from noxious air by telling the muscle cells encircling the lungs’ airways to contract This partially seals off the lungs An asthma attack occurs when the messenger molecules are...

Ngày tải lên: 17/10/2013, 15:15

... Third-party languages Several third-party languages are supporting the NET Platform These languages include APL, COBOL, Pascal, Eiffel, Haskell, ML, Oberon, Perl, Python, Scheme, and Smalltalk 16 Module ... Describe the NET Platform List the main elements of the NET Platform Describe the NET Framework and its components Explain the language support in the NET Framework 2 Module 1: Overview of the Microsoft ... garbage collection and security, are automatically provided 6 Module 1: Overview of the Microsoft NET Platform NET Framework Class Library The NET Framework class library exposes features of the runtime...

Ngày tải lên: 18/10/2013, 18:15

... Exchange alone, stock market capitalization declined from 11 .5 trillion dollars at the end of 19 99 and at the end of 2000 to 11 .0 trillion dollars at the end of 20 01 and to 9.0 trillion dollars at the ... of “market discipline” will object that, surely, markets take account of the risks that a bank is taking and will penalize the bank if these risks are excessive From this perspective, the relative ... should be harmful to them Akerlof’s (19 70) famous model of the used-car market is paradigmatic for the problem In Akerlof’s analysis, people who know their cars to be of good quality are less willing...

Ngày tải lên: 17/02/2014, 21:20

... 2: Risks facing the SAI F Examining the process and the results Risk Managing the risk 28) The SAI may lack the commercial • expertise needed to evaluate either how well the public sector partner ... of contingency planning (e.g share disposal) 16 Part 2: Risks facing the SAI F examining the process and the results G identifying worthwhile lessons H following up their work 17 Part 2: Risks ... worthwhile lessons H following up their work 10 The following sections set out sub-risks for each category together with suggestions on how they might be managed The risks are ordered chronologically,...

Ngày tải lên: 18/02/2014, 05:20

... constants of the 15 N nucleus of the distal NO and of the 14 N nucleus of the proximal His of the GmHO -1 complex are closer to those of the rHO -1 complex than to those of the SynHO -1 complex Thus, ... heme–HO -1 complexes T Gohya et al 15 NO-bound forms of Protein GmHO -1 SynHO -1 rHO -1 Alkaline Low spin g1 g2 g3 15 NO a (15 N), G a (14 N), G g1 g2 g3 Neutral Alkaline -1 Alkaline-2 2.63 2. 21 1.82 2.86 ... oxygenase -1 10 11 12 13 14 15 16 17 18 19 20 21 22 T Gohya et al ferredoxin-dependent heme oxygenase required for phytochrome chromophore synthesis Plant Physiol 14 0, 19 58 19 66 Emborg TJ, Walker...

Ngày tải lên: 19/02/2014, 05:20

... mutation Length/amino acids (without GST) TNP-ATP binding Kd (lM) Km (lM) Vmax (nmolặh )1 mg )1) L3 5 4L7 77 L3 54I604 I390S6 01 L3 54P588 L3 5 4L5 76 L3 5 4L5 41 L3 5 4L5 27 N398D (L3 54I604) D369A (L3 54I604) 324 2 51 ... than the r ẳ 0.34 of the FITClabeled and membrane-embedded Na+ /K+ ATPase [52] Additionally, to have a closer look to the rigidity of the FITC-labeled L3 54P588 H4-H5 loop, the lifetime of the excited ... Molecular modeling Molecular modeling of the H4-H5 cytoplasmic loop of the a subunit of Na+ /K+ ATPase ranging from L3 54 to L7 73 has been reported previously [20] Models of the cytoplasmic loop of...

Ngày tải lên: 19/02/2014, 16:20

... Wild-type M14 9K N152D G155P, K1 56S, G157E N152D, G155P, K1 56S, G157E G15 5K, D (15 6 15 7), A158E M14 9K, G15 5K, D (15 6 15 7), A158E N152D, G15 5K, D (15 6 15 7), A158E M14 9K, N152D, G15 5K, D (15 6 15 7), A158E ... variant PAI -1 variant Activity (%) t½ (min) Wild-type T96A F100A V126A F128A S129A E130A V131A E132A R133A R135A F136A I137A I138A N139A D140A W141A V142A K1 43A T144A H145A T146A K1 47A M149A N152A E283A ... twofold dilution series in a 96-well plate with 10 0 lL PAI -1 per well in concentrations ranging from 20 to 0.0098 lgÆmL )1 Immediately thereafter, 10 0 lL 0.5 lgÆmL )1 uPA (0.25 or 0 .12 5 lgÆmL )1 uPA...

Ngày tải lên: 20/02/2014, 11:20

... and of oligoriboadenylic acid alone at acidic pH J Mol Biol 62, 3 61 3 81 Supplementary material The following material is available from http:// www.blackwellpublishing.com/products/journals/suppmat/ ... of the structure of AII in solution with the X- ray structure of AII complexed to the Fab1 31 mAb In Fig 7A, a sequence alignment is represented of the backbone of the conformational ensemble of ... co-ordinates (the blue colour denotes the side chains of Arg2, Tyr4, Ile5, His6 and the yellow the side chains of Val3 and Pro7) (a) with the the X- ray structure of AII in the Fab1 31 AII complex [30]...

Ngày tải lên: 20/02/2014, 23:20

... (19 99) ˚ The 2.8 A crystal structure of visual arrestin: a model for arrestin’s regulation Cell 97, 257–269 11 Palczewski, K. , Pulvermuller, A., Buczylko, J & Hofmann, K. P (19 91) Phosphorylated ... the intrinsic 48-kDa protein of rod outer segments Proc Natl Acad Sci USA 83, 11 74 11 78 29 Palczewski, K. , Buczylko, J., Imami, N.R., McDowell, J.H & Hargrave, P.A (19 91) Role of the carboxyl-terminal ... dimer allows us to design experiments to study the precise role of the C-terminal domain and the biological function of the arrestin dimer ACKNOWLEDGEMENTS The assistance of Michel Koch at beamline...

Ngày tải lên: 22/02/2014, 07:20

... structure and the homology classes of analytic cycles: if X is a compact K hler manifold, the K hler cone K of X is one of the connected components of a a the set P of real (1, 1) -cohomology classes ... with K hler metrics Clearly, K is an open convex cone in H 1, 1 (X, R), a since a small perturbation of a K hler form is still a K hler form The closure a a K of the K hler cone is equally important ... in a purely formal way from the Main Theorem: Corollary 0.2 Let X be a projective manifold Then the K ahler cone of X consists of all real (1, 1) -cohomology classes which are numerically positive...

Ngày tải lên: 05/03/2014, 23:20

... Cell 10 0, 311 –3 21 Kononenko AV, Dembo KA, Kisselev LL & Volkov VV (2004) Molecular morphology of eukaryotic class I translation termination factor eRF1 in solution Mol Biol (Mosk) 38, 303– 311 ... using Clore’s extension of the Lipari and Szabo model [37] The axial symmetry with the ratio Dk ⁄ D^ of the principal axis of the tensor was 1. 8 ± 0 .1; the value of effective overall correlation ... completely conserved among all species, including members of the archaea, namely Pro177, Lys179 and Ser186 in the loop region, and Arg189, Phe190 and Leu193 at the beginning of the a1 helix The highly...

Ngày tải lên: 07/03/2014, 05:20

... as gray loops near the a-helix to which they were docked The RC -10 1 molecules docked to HR1 are much more dispersed than the RC -10 1 molecules docked to HR2 The color of each residue of HR1 and ... ability of the JR.FL pseudotypes, HOS-CD4-CCR5 cells (5 · 10 3 per well; 96-well plate) were infected with 50 ng p24 per well of virus in the presence or the absence of RC -10 1 (0, 1. 25, 2.5, or 10 ... clinical HIV -1 isolates from five different clades [8 ,11 ] Retrocyclins act prior to viral entry into host cells by disrupting the function of glycoprotein 41 (gp 41) of HIV -1 [12 ,13 ] Retrocyclin...

Ngày tải lên: 07/03/2014, 05:20

... ()2. 71 · 10 7 radÆs )1 T )1) and 1H (2.68 · 10 8 radÆs )1 T )1) , h is the Planck constant, xN is the Larmor frequency of the 15 N, xH is the Larmor frequency of the 1H, is the ˚ length of the amide ... overall (global) and internal (local) motions (i.e the internal motions of the bond vectors are independent of the overall rotational movement of the molecule) Furthermore, the internal motions of ... of 12 .3 s )1 (range 9 .1 14 .0); the second a-helix presented a mean of 13 .2 s )1 (range 11 .9 14 .2); the third a-helix presented a mean of 11 .3 s )1 (range 8 .19 – 13 .5); and, finally, amino acids in the...

Ngày tải lên: 07/03/2014, 06:20

... Chem Soc 11 1, 7296–7300 18 Bertini I, Luchinat C, Messori L & Vasak M (19 89) Proton NMR spectra of the Co4S 11 cluster in metallothioneins: a theoretical model J Am Chem Soc 11 1, 7300–7303 19 Bertini ... R, Billeter M & Wuthrich K (19 96) molmol: a ¨ program for display and analysis of macromolecular structures J Mol Graph 14 , 51 32 Supplementary material The following supplementary material is ... of rat metallothionein-2 Proc Natl Acad Sci USA 89, 10 124 10 128 16 Messerle BA, Schaffer A, Vasak M, Kagi JH & Wuthrich K (19 92) Comparison of the solution conformations of human [Zn7]-metallothionein-2...

Ngày tải lên: 07/03/2014, 09:20