... library (7th edition) Results and discussion The complex hydrocarbons and fatty acids produced by the cultured photobiont green alga Trebouxia sp and the mycobiont, and also by X parietina, were ... medicines, and is used in many Asian countries [40] It has also been found as a major effluent component in the paper and pulp industry [41] and is one of the toxic compounds accumulated in fish and other ... Trebouxia erici and Trebouxia impressa (cultures from the Botanical Institute, St Petersburg, Russia) not contain the 18 : and 18 : fatty acids, and produce only two fatty acids: 16 : (30% and 51%,...
Ngày tải lên: 23/03/2014, 17:21
... production and concentrations of cyclin D1, Rb and Egr-1, in order to determine how the incorporation of EPA and DHA modulate SMC proliferation This article describes the differing effects of n-3 and ... the first-strand cDNA and 300 nM primers Amplification was performed on an iCycler (Bio-Rad), according to the manufacturer’s instructions, and cycle parameters were: 50 °C (2 min) and 95 °C (10 ... with the )973 bp cyclin D1 gene promoter and either the dominant-positive or the dominant-negative Ras and Raf mutants, and the effects of incorporated n-6 and n-3 PUFAs were explored in cells treated...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: Alpha-oxidation of 3-methyl-substituted fatty acids and its thiamine dependence pptx
... van de Vlaamse GemeenschapÕ (GOA 94/98–12 and GOA 99/03–09) and from the ÔFonds voor Wetenschappelijk Onderzoek-VlaanderenÕ (G-0239.98, G.0164.96 N and G.0115.02) V.F was supported by a fellowship ... Subsequent measurements of formate (plus formyl-CoA, see below) and CO2 resolved the discrepancies between intact and permeabilized/broken systems and allowed for the dissection of the a-oxidation process ... phytanic acid and 3-methyl-adipic acids in patients with Adult Refsum’s disease In Peroxisomal Disorders and Regulation of Genes, 25–28 September 2002, Belgian Society for Cell and Developmental...
Ngày tải lên: 08/03/2014, 02:20
Báo cáo khoa học: Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids docx
... n-3 PUFA and particularly an n-3 DPA and EPA An increase in n-3 DPA and EPA, and perhaps other n-3 PUFAs, stimulates Jak2 and Stat5 activation, and induces b-casein expression and gland differentiation ... killed at 6, 8, 10, 12 and 14 weeks and subjected to whole mount morphological analysis The right inguinal gland was removed and subjected to whole mount gland fix, defat, and staining Representative ... increase in n-3 DPA and EPA in pregnant glands versus control glands is observed (Table 1) Whereas there was an abundant DHA in the virgin control gland, the amount of DPA and EPA was either undetectable...
Ngày tải lên: 16/03/2014, 10:20
Báo cáo khoa học: Cytochrome P450 metabolizing fatty acids in plants: characterization and physiological roles pptx
... [47] and by FA derivatives such as prostaglandins Clofibrate produces similar effects in plants and animals [8,45] Furthermore, there are evident structural analogies between prostaglandins and ... only one CYP703 [37] CYP704B1 and CYP704B2 belong to a conserved and ancient P450 family in moss and seed plants This suggests that reactions catalysed by CYP703 and by members of the CYP704 subfamily ... C18:1, C18:2 and C18:3 [21] Physiological role Characterization of the first FA-metabolizing P450 enzymes showed that they exhibited different regioselectivities and substrate specificities and were...
Ngày tải lên: 22/03/2014, 16:21
Effects of dietary n-3 and n-6 fatty acids levels on egg and larval quality of Eurasian perch pdf
... (Dicentrarchus labrax) Aquaculture, 149: 107-119 LANDS, W.E.M., 1989 - Differences in n-3 and n-6 eicosanoid precursor In: Advances in prostaglandin, thromboxane and leukotriene research (Samuelsson B., ... Eurasian perch egg and larval quality Henrotte et al References BELL J.G., FARNDALE B.M., BRUCE M.P., NAVAS J.M & M...
Ngày tải lên: 02/07/2014, 22:21
báo cáo khoa học: " Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity" pot
... formazan product, and subjected to spectrophotometric analysis at 570 nm Protein analysis Methods Cell lines and tissue culture SW620, MCF-7 and RAW264.7 were purchased from ATCC and cultured in ... protein levels in cell lysates and conditioned media (Figures 7B and 7C, respectively) Consistent with the above findings, transcript levels of COX2 and IL-1b (Figures 8A and 8B), as well as IL-1b ... NFB, IBa and NOS2 in SW620 cells treated with three concentrations of GTA+ve and GTA-ve extracts and doxorubicin (DOX) Representative Western blots showing protein levels of NFB, IBa and NOS2...
Ngày tải lên: 10/08/2014, 10:21
Báo cáo y học: " Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33 000 women from the general population" ppt
... Eicosapentaenoic acid and arachidonic acid: collaboration and not antagonism is the key to biological understanding Prostaglandins Leukot Essent Fatty Acids 2002, 66(1):83-90 Simopoulos A, Cleland L: Omega-6/Omega-3 ... the Scandinavian Women's Lifestyle and Health Cohort [19,20] The women were asked to fill in a paper questionnaire, including a food frequency questionnaire (FFQ), and levels of fish, PUFAs and ... the questionnaires and were enrolled in the study In 2002/2003 a follow-up study was initiated, and women who had responded to the 1991/1992 questionnaire and who were alive and living in Sweden...
Ngày tải lên: 11/08/2014, 16:22
Báo cáo y học: "Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial" docx
... atmosphere and at 37°C After this, the supernatant medium was collected and stored at -70°C until analysis (within nine months) Cytokine and eicosanoid analyses Cytokines, prostaglandin (PG) E2 and ... circulating inflammatory cytokine concentrations and would reduce length of ICU and hospital stay Materials and methods Study design This study was a randomized, single blinded investigation of a ... were measured in plasma and cytokines and PGE2 in whole blood culture supernatants Cytokines and eicosanoids were measured using enzyme-linked immunosorbent assays (ELISA) and following the manufacturer's...
Ngày tải lên: 13/08/2014, 20:21
THE EFFECT OF OMEGA-3 FATTY ACIDS ON AIRWAY INFLAMMATION, HYPERPNEA-INDUCED BRONCHOCONSTRICTION, AND AIRWAY SMOOTH MUSCLE CONTRACTILITY IN ASTHMA
... early and a late phase In the early phase, mast cells and macrophages in the airways are activated and release proinflammatory mediators such as histamine, leukotrienes, prostaglandins, and reactive ... Diet and Asthma 10 Omega-3 Fatty Acids and Smooth Muscle Contractility 18 Summary and Proposed Experimental Aims 21 CHAPTER 2: THE EFFECT OF FISH OIL, VITAMIN C, AND THEIR ... polyunsaturated fatty acids Omega-3 and -6 polyunsaturated fatty acids compete for the 5-lipoxygenase and cyclooxygenase enzymes to produce leukotrienes and prostaglandins with different proinflammatory...
Ngày tải lên: 24/08/2014, 12:48
modulation of the structure and dynamics of acyl-acyl carrier protein by fatty acids of different length
Ngày tải lên: 14/11/2014, 10:21
Enhanced transdermal delivery with fatty acids and electroporation
... for CsA and for diseases such as psoriasis and atopic dermatitis, topical CsA has displayed superior efficacy and reduced side effects (Hewitt and Black, 1996) However, like most peptides and proteins, ... stretching vibrations give rise to bands in the spectral region 3100-2800 cm-1 and the strongest bands in the spectra of lipids correspond with the CH2 asymmetric (νa(CH2)) and symmetric (νs(CH2)) stretching ... be a useful tool in understanding the conformation of the SC lipids and proteins by looking at the shift in wavenumber frequencies and the intensity of absorption bands 2.7 Transdermal Delivery...
Ngày tải lên: 12/09/2015, 10:37
Effects of central nervous system free fatty acids, prostaglandins and lysophospholipids on allodynia in a mouse model of orofacial pain
... and intracerebroventricular free fatty acids, prostaglandins and lysophospholipids compared to control mice 33 MATERIALS AND METHODS 34 Ethical concerns Animals in this study were cared for and ... noxious stimuli (Cridland and Henry, 1986) In the dorsal horn, both nociceptive and low-threshold neurons are readily excited by substance P (Salt et al., 1983; Dougherty and Willis, 1991) 11 ... are provided to the face and oral cavity and the motor innervations to the muscles of mastication The three main trigeminal nerve divisions: ophthalmic, maxillary and mandibular, together constitute...
Ngày tải lên: 05/10/2015, 13:53
FATTY ACID COMPOSITION INCLUDING TRANS FATTY ACIDS CONTENT OF SELECTED VIETNAMESE INSTANT NOODLES
... composition and nutritional values in this small additive oil bag was not indicated Obviously, this might lead to misunderstanding and/ or misinformation about the true qualities and nutritional ... significant higher in brands IN1 and IN5, 0.7% and 0.83%, respectively The significant lower value was identified with brands IN14, IN12, and IN16, with 0.16%, 0.17% and 0.19%, respectively The ... supermarkets and general stores between May and August 2011 with manufacture date from April to July 2011 Each brand was coded with letter from IN1 to IN16 The small oil bag taken from thirteen brands...
Ngày tải lên: 28/08/2013, 16:28
Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas
... 18:2n6c and LCFAs were contained in greater amounts in the roots and rhizomes than in the leaves and stems, and 18:3n3 was contained in lesser amounts in the roots and rhizomes than in the leaves and ... of 18:2n6c, 18:3n3 and LCFAs in the leaves and stems was compared with that in the roots and rhizomes The roots and rhizomes contain more 18:2n6 and LCFAs than the leaves and stems (n = 15, p ... Meanwhile, Z marina in the leaves and stems has -9.7 ± 1.0‰, and in the roots and rhizomes has -9.6 ± 1.0‰ Fig shows that the leaves and stems as well as the roots and rhizomes of Z j aponica have...
Ngày tải lên: 05/09/2013, 10:17
Tài liệu VAI TRÒ CUẢ OMEGA-3 FATTY ACIDS TRONG VIỆC ĐIỀU TRỊ VÀ PHÒNG NGỪA BỆNH doc
... phospholipid làm giảm mức độ eicosanoids xuất xứ từ AA cách giảm mức độ diếu-tố dùng để biến AA prostaglandins leukotrienes; DHA 22carbon fatty acid không trực tiếp biến thành eicosanoids, nhiên, DHA ... đổi LNA EPA DHA không cho đủ lượng LC n-3 PUFA Đối với đàn ông, 3% tớI 8% cuả 1.3g LNA biến EPA and 0% tới 4% EPA biến đổi DHA Đối với đàn bà, 21% EPA biến 9% kéo dài thành DHA Sự biến đổi bị ... n-3 fatty acids, EPA, DHA huyết đưa tới nguy lớn chết bất đắc kỳ tử Cuộc nghiên cứu DART (Diet and Reifarction Trial) khuyên người đàn ông sống sau bị tim kích, nên tiêu thụ nhiều cá có dầu (khoảng...
Ngày tải lên: 24/01/2014, 04:20
Tài liệu Báo cáo khoa học: Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation ppt
... substrates Materials and methods Materials Sodium salt and free acid forms of oleic, stearic and arachidonic acids were purchased from Sigma-Aldrich Kft (Budapest, Hungary) and stock solutions ... mean (symbols) and standard deviation (cross-lines) of four measurements Lines represent best global fit of the data set to the equation of Model I described in the Materials and methods The ... limit below the estimated Km value and upper limit at least 5-fold higher than the Km estimate) The final best estimates of the catalytic constant (kp) and the Km, and their confidence intervals, are...
Ngày tải lên: 18/02/2014, 17:20
Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx
... long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8 Arch Biochem Biophys 441, 174–181 19 Kandel S, Sauveplane V, Olry A, Diss L, Benveniste ... (53%), x-2 (15%), x-3 (8%), x-4 (18%) and x-5 (6%) For substrate oxidation, we determined, by kinetic studies, Km,app and Vmax,app values of 172 ± 13 lm and 117 ± nmolÆmin)1Ænmol)1 P450, respectively ... acid, and was indeed identified as 9,10-epoxystearic acid by GC ⁄ MS analysis (Fig S4) For substrate oxidation, we determined, by kinetic studies, Km,app and Vmax,app values of 84 ± 23 lm and 26...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Mutants of Saccharomyces cerevisiae deficient in acyl-CoA synthetases secrete fatty acids due to interrupted fatty acid recycling docx
... intracellular and extracellular fatty acids of YB526 and MS51 The cells were grown in YPR medium and harvested at different time points during the exponential and stationary phases Medium and cells ... were removed by centrifugation and the supernatant was extracted and tested for free fatty acids For strains carrying a combined deletion of FAA1 and FAA2 or of FAA1 and FAA3, we did not observe ... Intracellular and extracellular lipid extractions were performed using heptadecanoic acid (17:0) as internal standard for free fatty acids (1 lg for wild-type and 10 lg for mutant cells) and triheptadecanoylglycerol...
Ngày tải lên: 07/03/2014, 05:20