nsabp b 39 rtog 0413 multicentre randomized apbi trial

... specified time Serum complete blood count and biochemical profile, as well as hepatitis serology (HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc) was obtained at baseline and then every weeks ... non-responders to interferon-based Table 3: Virologic, Biochemical Variables of Patients at 24 weeks After Treatment Variable ALT normalization, n (%) Loss of HBV-DNA, n (%) HBeAg/anti-HBe seroconversion, ... was defined as HBeAg seroconversion, loss of HBeAg and non-detectable HBV-DNA level, and biochemical response as normalization of ALT level The virologic and biochemical responses between the two...

Ngày tải lên: 12/08/2014, 04:22

... group sequential boundaries for monitoring clinical trials Biometrika 1982, 69:661-663 Jennison C, Turnbull BW: Group Sequential Methods with Applications to Clinical Trials Boca Raton, FL: CRC ... confidence bounds will be much wider than they would have been had the study continued Furthermore, the estimated treatment difference is biased downward There are ways to compensate for this but they ... ALVEOLI trial was complicated further by baseline differences between groups with respect to two important predictors of survival: age and severity of lung injury Adjusting for these imbalances,...

Ngày tải lên: 12/08/2014, 20:20

... PHƯƠNG PHÁP CHẾ BIẾN VÀ DỰ TRỮ THỨC ĂN Các phương pháp chế biến thức ăn: Thức ăn vật nuôi chế biến phương pháp vật lý biểu thị hình: ………… Hình ,2 ,3 B ng phương pháp hóa học biểu thị hình:…………… ... hình:…………… Hình ,7 Hình B ng phương pháp vi sinh vật học biểu thị hình:……… Hình B ng phương pháp tạo thức ăn hỗn hợp:……… Các phương pháp chế biến thức ăn: Cho biết có phương pháp chế biến thức ăn? a.Phương ... B I 39: CHẾ BIẾN VÀ DỰ TRỮ THỨC ĂN CHO VẬT NUÔI Người dạy: Lê Thị Thu Lành_1 1B2 I MỤC ĐÍCH CỦA CHẾ BIẾN VÀ DỰ TRỮ THỨC ĂN Thức nhận xét vị không...

Ngày tải lên: 14/07/2014, 19:00

... vaccination Methods We conducted a double blind, randomized, controlled trial using two different concentrations of HBV vaccine 10 or 40 µgs (Recombivax, HB, Merck, Sharp &Dohme, USA), in two ... Therapy 2006, 3:9 Background Hepatitis B virus (HBV) is one of the major causes of acute and chronic hepatitis worldwide that can be prevented by immunization [1,2] Co-infection with HVB and human ... the hepatitis B virus carrier state J Infect Dis 1991, 163:1138-1140 Koblin B, Taylor P, Rubinstein P, Stevens C: Effect of duration of hepatitis B virus infection on the association between human...

Ngày tải lên: 10/08/2014, 05:20

... will not be held (a) No one except for the seven – year – old boy witnessed the accident (b) No one at all saw the seven – year – old boy’s terrible accident (c) The seven – year – old boy saw ... 7:30, but this morning I woke up early (b) This morning I woke up at 7:30, but I usually wake up late (c) This morning I slept later than I intended (d) This morning I woke up at 7:30, but I ... offered $1000 for the car but the man disagreed (b) George wanted more than $1000 for the car (c) The man wanted more than $1000 for the car (d) George offered $1000 for the car but the man shook his...

Ngày tải lên: 29/10/2014, 07:00

... will be used to analyze continuous outcome variables, and logistic models for binary outcome variables All analyses will be adjusted for hospital, baseline values of the outcome measure, and baseline ... 337:a 2390 Campbell MK, Elbourne DR, Altman DG, for the CONSORT group: CONSORT statement: extension to cluster randomized trials BMJ 2004, 328:702-708 van de Poll-Franse LV, Horevoorts N, van Eenbergen ... 16:249-254 Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC, Kaasa S, Klee M, Rofe PB, Schraub S, Sneeuw K, Sullivan M, Takeda...

Ngày tải lên: 05/03/2014, 15:20

... as needed There were 139 loan groups at baseline, each overseen and administered by one of four loan officers hired by PRISMA At baseline, this branch provided no services beyond the lending services ... population-based intervention trial Bull World Health Organ 2005, 83(1):27-33 Hamad et al BMC Public Health 2011, 11:51 http://www.biomedcentral.com/1471-2458/11/51 Page 10 of 10 37 Harkins T, Drasbek ... clients in Peru: a randomized controlled trial BMC Public Health 2011 11:51 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • Thorough...

Ngày tải lên: 05/03/2014, 22:21

... social ability and/or fear of reprisals, or because of a sensation of relief at having gone through a safe experience and having a healthy baby [9,10] However, this effect would probably be the ... nurses as providers of birth labor support in North American hospitals: a randomized controlled trial JAMA 2002, 288:1373-81 Brown S, Lumley J: Satisfaction with care in labor and birth: a survey of ... in PubMed and archived on PubMed Central yours — you keep the copyright BioMedcentral Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp Page of (page number not...

Ngày tải lên: 14/03/2014, 16:20

... comfortable.’ Subject ‘I feel more relaxed.’ Subject ‘Before the practice, my upper limb of the affected side could only raise up a little Now, both hands could raise above my head.’ Subject No ... My mobility of both upper and lower limbs improved I feel relaxed and better.’ Subject No comment regarding psychosocial functioning Subject No comment regarding psychosocial functioning Subject ... 0.001 < 0.001 < 0.001 Subject ‘I feel better and more relaxed.’ Subject ‘I feel better, more comfortable and sleep well.’ Feedback after less than six weeks of practice Subject ‘I have practiced...

Ngày tải lên: 28/03/2014, 19:21

... Balance Virtual Rehabilitation), a system based on the Nintendo® Wii Balance Board® (WBB), which has been designed by clinical therapists to improve standing balance in patients with ABI through motivational ... clinical balance scales not only during static condition but also during dynamic tasks On one hand, balance in static condition was assessed by the Berg Balance Scale (BBS) [28], the Brunel Balance ... of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury Journal of NeuroEngineering and Rehabilitation...

Ngày tải lên: 19/06/2014, 08:20

... Clin Trials 2002, 3(1):45-51 Kenya Demographic Health Survey: Central Bureau of Statistics, Nairobi Kenya; 2003 Wamalwa D, Farquhar C, Obimbo E, Selig S, Mbori-Ngacha DA, Richardson BA, Overbaugh ... Results Description of study subjects A total of 115 children were enrolled between September 2004 and November 2005, of whom 99 were randomized We defined adherence as being >95% if the caregiver ... http://www.jiasociety.org/content/12/1/8 B D Figure reported adherence by arm ViralSelf Loess curves by study study arm; B – Weight-for-age Loess curves by study arm; C – CD4 count by study arm; D – A – load...

Ngày tải lên: 20/06/2014, 08:20

... vitamins A, B1 , B2 , niacin, B6 , B1 2, C, D and E, folate, zinc, copper, iodine and selenium; the comparative "standard-of-care" supplement consisted of the RDA (1 RDA) of vitamins A, C, D, B1 , B2 and ... of blood was collected in a 5ml EDTA vacutainer tube (Becton Dickinson, Franklin Lakes, N.J.) by venipuncture from the cubital fossa or dorsum of the hand, and was analyzed for a complete blood ... available article distributed under the article is International AIDS Society 2010, 13:18 References Brahmbhatt H, Kigozi G, Wabwire-Mangen F, Serwadda D, Lutalo T, Nalugoda F, Sewankambo N,...

Ngày tải lên: 20/06/2014, 08:20

... conceived and planned by both the authors TN collected the data under supervision by RK The paper was jointly written by both the authors References Gibson JS, Horn SH, Powell JM, Gibbson JL: Schizophrenic ... about age, sex, educational level, birth order, number of siblings, marital status, number of children, occupation and work status, and to gather details about the illness (age at onset, number ... scale measures objective and subjective aspects of burden and it contains six general categories of burden, each having two to six individual items for further investigation Subcategories include:...

Ngày tải lên: 08/08/2014, 23:21

... and/or advisory board member for the following companies: Abbott Immunology, Allergan, Almirall, AlPharma, Amgen Corporation, AstraZeneca, Bayhill, Bexel, BiogenIdec, Bioseek, BMS, CanFite, Centocor, ... arthritis: double-blind randomised controlled trial Lancet 2004, 363:675-681 Jones G, Gu JR, Lowenstein M, Calvo A, Gomez-Reino JJ, Siri D, Tomsic M, Blackburn R, Woodworth T, Sebba A: Tocilizumab monotherapy ... subjects with active rheumatoid arthritis on a background of methotrexate: A phase double blind, placebo controlled, parallel, randomized study [abstract] Ann Rheum Dis 2006, 65(Suppl II):339...

Ngày tải lên: 09/08/2014, 01:22

... free drug and placebo from Biogen, Cambridge, MA, USA Acknowledgement This study was supported by grant support through Biogen Study medication was also provided by Biogen, Cambridge, Mass References ... treatment of RA in a doubleblind, placebo-controlled fashion The investigators initially planned to enroll 40 patients This number was based on the maximum number thought possible to enroll as well ... [package insert] Cambridge, MA: Biogen, Inc; 2000 Rep MH, Hintzen RQ, Polman CH, van Lier RA: Recombinant interferon-beta blocks proliferation but enhances interleukin10 secretion by activated human...

Ngày tải lên: 09/08/2014, 01:23

... for randomized controlled trials occurs Design bias Design bias, on the other hand, occurs before the RCT is begun, when the trial parameters are determined and before the final decision has been ... ‘publication bias’, discussed below, might have played a role Finally, we suggest that a relatively undiscussed bias, ‘design bias’, is likely to have contributed substantially to the predictability ... believed a trial to be unethical if equipoise was disturbed beyond 70:30, and 97% believed it unethical if equipoise were disturbed beyond 80:20 [4] It was recently argued that perceptions of basic...

Ngày tải lên: 09/08/2014, 01:23

... Cortet B, Flipo RM, Pigny P, Duquesnoy B, Boersma A, Marchandise X, Delcambre B: Is bone turnover a determinant of bone mass in rheumatoid arthritis? J Rheumatol 1998, 25:2 339- 2344 41 Forsblad ... 31 32 bone resorption by directly inducing apoptosis of the boneresorbing osteoclasts J Exp Med 1997, 186:489-495 Chow J, Tobias JH, Colston KW, Chambers TJ: Estrogen maintains trabecular bone ... changed E2 levels Available online http://arthritis-research.com/content/6/5/R457 Table Baseline correlations between biochemical markers of bone and cartilage metabolism, bone mineral density,...

Ngày tải lên: 09/08/2014, 01:24

Ngày tải lên: 09/08/2014, 06:22

... Pa one CD3+ T Before lymphocytes After CD38+ plasma Before cells After CD68+ Before macrophages After Intra-observer Observer comparison Observer Placebo Prednisol Pa one Pb Placebo Prednisol ... Table There were no statistically significant differences in the mean change in positive cells between the analyses by the three observers (OB1 t0, OB2 and OB3) When the overall correlations between ... placebo group; and for CD68+ Interrater reliability The mean number of T cells, plasma cells and macrophages before and after intervention measured by the other two observers (OB2 and OB3) are...

Ngày tải lên: 09/08/2014, 06:23

... article is available article distributed under the Ltd References Resbeut M, Marteau P, Cowen D, Richaud P, Bourdin S, Dubois JB, Mere P, N'Guyen TD: A randomized double blind placebo controlled ... respectively For the 32 eligible patients who received radiotherapy and lactobacillus acidophilus plus bifidobacterium bifidum, the overall Page of 63 randomized Placebo capsules before meals times a ... probiotic supplementation and an elemental diet may be beneficial in preventing symptoms The objective of our study was to test the efficacy of lactobacillus acidophilus plus bifidobacterium bifidum...

Ngày tải lên: 09/08/2014, 08:23