... Aβ generation; and (4) sorting of APP and/ or its α -and -carboxyl-terminal fragments (C83 and C99, respectively) toward the trans-Golgi network is under the influence of presenilins and the VPS35/retromer. ... sorting and neurotransmission (Mostov and Cardone 1995; Clague and Urbe 2001; Bonifacino and Traub 2003). A striking ex ample ∗ Reprinted in part from Neuron (2006), with permission. S. Gandy Mt ... site-2 (S2P) metalloprotease (Brown and Goldstein 1999), the GxGD-type aspartyl proteases (Haass and Steiner 2002) and the rhomboid serine proteases (Lemberg and Freeman 2007) (Fig. 1). ICLIP turned...
Ngày tải lên: 14/02/2014, 17:20
... distribution, and reproduction in any medium, provided the original work is properly cited. Photoreceptor Sensory Cilium and Associated Disorders Linjing Li, Ozge Yildiz, Manisha Anand and Hemant ... diseases, and photoreceptor degeneration and blindness [6-7, 16-18]. 2. Photoreceptor sensory cilium and its components In photoreceptors (rods and cones), cilia are highly specialized and modified ... blindness and loss of peripheral vision (due to rod death) in the Photoreceptor Sensory Cilium and Associated Disorders 55 [22] Insinna, C. and Besharse, J. C. Intraflagellar transport and the...
Ngày tải lên: 19/02/2014, 22:20
LifeOut of Focus Alzheimer’s Disease and Related Disorders ppt
... successful, and well respected in her community. At home, she and her husband especially enjoyed spending time with their six grandchildren. There, Helen could put numbers and finances and tax forms ... the United States and in several foreign countries. 14 LIFE OUT OF FOCUS: ALZHEIMER’S DISEASE AND RELATED DISORDERS The children were all grown and on their own when her husband retired from ... stillness. And silence. Helen and Mary died within a month of each other, two years after 20 LIFE OUT OF FOCUS: ALZHEIMER’S DISEASE AND RELATED DISORDERS Late one night, police found Helen wandering...
Ngày tải lên: 05/03/2014, 23:20
RESPIRATORY HEALTH EFFECTS OF PASSIVE SMOKING: LUNG CANCER AND OTHER DISORDERS ppt
... standard deviation, and maximum and minimum nicotine values measured in different indoor environments with smoking occupancy 3-23 3-5 Mean, standard deviation, and maximum and minimum concentrations of ... SMOKING: LUNG CANCER AND OTHER DISORDERS Major funding for this report has been provided by the Indoor Air Division, Office of Atmospheric and Indoor Air Programs Office of Health and Environmental ... 5/6: Kenneth G. Brown 3 Chapter 7: Fernando D. Martinez 4 Chapter 8: Fernando D. Martinez and Steven P. Bayard Appendix A: Kenneth G. Brown, Neal R. Simonsen, and A. Judson Wells 3 3 Appendix B:...
Ngày tải lên: 15/03/2014, 01:20
Fatty Liver Disease: NASH and Related Disorders ppt
... the pathophysiology of NAFLD and is present even in NAFLD patients who are normal weight and have normal carbohydrate tol- erance [102,103]. Although the initial site and cause of insulin resistance ... of Gastroenterology, MetroHealth Medical Center and Schwartz Center for Metabolism and Nutrition, Cleveland, OH 44102-1998, USA EPIDEMIOLOGY AND RISK FACTORS OF NASH 35 97 Navarro VJ, St. Louis ... obesity and type 2 diabetes mellitus in the USA and elsewhere, clinicians and investigators have developed an appreciation for the link between non-alcoholic fatty liver disease (NAFLD) and hepatic...
Ngày tải lên: 22/03/2014, 16:20
báo cáo hóa học: " Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders" pptx
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "CLOCK is suggested to associate with comorbid alcohol use and depressive disorders" ppt
Ngày tải lên: 10/08/2014, 09:20
Tài liệu SLEEP-RELATED BREATHING DISORDERS EXPERIMENTAL MODELS AND THERAPEUTIC POTENTIAL docx
... measurements of sleep and breathing, and in miniaturization of the techniques used in rats. This chapter summarizes techniques currently used to measure sleep and breathing in rats and mice, and also ... Revised and Expanded, edited by L. B. Reichman and E. S. Hershfield 145. Combination Therapy for Asthma and Chronic Obstructive Pulmonary Disease, edited by R. J. Martin and M. Kraft 146. Sleep ... knowledge regarding sleep- related breathing disorders (SRBD). Significant strides have been made in our understanding of these disorders with respect to epidemiology and risk factors, pathogenesis, clinical and...
Ngày tải lên: 14/02/2014, 17:20
báo cáo hóa học: "Evaluation of the impact of fibromyalgia on patients'''' sleep and the content validity of two sleep scales" pptx
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học:" Evaluation of the impact of fibromyalgia on patients'''' sleep and the content validity of two sleep scales" ppt
Ngày tải lên: 20/06/2014, 16:20
Tài liệu MENTAL DISORDERS THEORETICAL AND EMPIRICAL PERSPECTIVES pptx
Ngày tải lên: 18/02/2014, 04:20
Diseases And Disorders ppt
... 12 Overviews Aging, disorders of 20 Arteries, disorders of 62 Birth defects 90 Bladder disorders 97 Blindness 99 Blood disorders 103 Bone and joint disorders 111 Brain disorders 117 Cancer ... disorders 172 Childhood disorders 188 Deafness 232 Dental and oral cavity disorders 241 Diagnosis 262 Digestive system disorders 273 Disabilities 282 Ear disorders 294 Environmental disorders ... 480 Kidney disorders 490 Liver and spleen disorders 521 Male reproductive system 539 Mental disorders 557 Metabolic disorders 570 Muscle system disorders 595 Nervous system disorders 604...
Ngày tải lên: 06/03/2014, 00:20
Diseases and Disorders: Speech Disorders ppt
... Disorder? 19 Common speech disorders in adults include fluency disor- ders like stuttering, voice disorders, and motor speech disor- ders, such as apraxia and dysarthria. Apraxia and dysarthria generally ... words. Speech disorders among children are many and varied. 9781420502213_DD.indd 7 4/3/10 11:11 AM Challenges Associated with Clefts Cleft palates and lips are not life threatening and, and in most ... damages, and the prognosis for normal speech and appearance is very good. Children born with clefts in developing countries are not so lucky. They are likely to suffer the physical and emotional...
Ngày tải lên: 06/03/2014, 00:20