neurological control of the bladder in health and disease

... establish baseline data in these infants Most of these studies to date have involved the measurement of these analytes individually In the studies presented in this thesis, we measured a range of stool ... material daily in a healthy adult Adults also both ferment and recycle the products of protein metabolism, including hydrolysis of urea, deamination of amino acids, and recycling of ammonia Nitrosation ... activity in a cohort of preterm infants in health and disease Dr Lynne Mary Beattie, MRCPCH MBChB PGCertMedEd Submitted in fulfilment of the requirements for the degree of Doctorate of Medicine School...

Ngày tải lên: 22/12/2014, 21:27

... phosphine is a quick and effective tool for the control of stored-product insect pests In view of the scheduled phaseout of methyl bromide under the Montreal protocol, the role of phosphine in grain ... of all oils tested The main component of one of the oils is pulegone The other is not yet identified and it is called SEM76 (Shaaya and Kostyukovsky, 2006) In our study of the mode of action of ... evaluate the toxicity of allyl ITC in grain, we could show that 20 μL·L−1 air (=20 g m−3 ) and exposure time of day were not effective in killing the insects at the bottom of the column when the fumigant...

Ngày tải lên: 25/10/2013, 05:20

... involved in ligand binding, presumably abolishing the interaction with signaling partners The remaining mutations alter amino acids located outside the ligand-binding pocket and reduce protein ... the linker B kinase region of SYK The PH domain of TFKs usually binds to phosphatidylinositol-3,4,5-trisphosphate, thereby bringing them in close proximity to other membrane-tethered signaling ... SH2 and kinase domains of BTK with coloring of residues affected by missense mutations Top left: locations of the missense mutation in the BTK PH domain; arginine 28 is in dark blue, encircled in...

Ngày tải lên: 14/02/2014, 18:20

... occludens-domain-containing proteins such as syntenin, Ga-interacting protein (GAIP)-interacting C-terminus ⁄ synectin and calcium ⁄ calmodulin-associated serine kinase, since the C2 region contains a ... catalytic domain with a zinc-binding site (Zn, HEXXHXXGXXH) and a conserved methionine (Met-turn) supporting the catalytic zinc Interaction between cysteine–zinc maintains proMMPs in an inactive state ... full-length TIMP-1 and TIMP-3 are [31] The C-terminal domain of TIMPs can stabilize proMMP by binding to its hemopexin domain, leaving the N-terminal fully capable of interacting with other MMPs Most...

Ngày tải lên: 15/03/2014, 23:20

... degree of fulness in the system, which places the nurse on the brink of disease, and which of itself frequently puts a stop to the secretion of the milk, instead of increasing it The right plan of ... impaired SYMPTOMS. The earliest symptom is a dragging sensation in the back when the child is in the act of sucking, and an exhausted feeling of sinking and emptiness at the pit of the stomach afterwards ... against, that of covering up the infant in its cot with too much clothing throwing over its face the muslin handkerchief and, last of all, drawing the drapery of the bed closely together The...

Ngày tải lên: 23/03/2014, 02:20

... explain the paradox of millions who successfully  The influence of the media and their role in product marketing represent one of the key developments of modern society Effective advertising and ... discounting, and brand marketing, in the context of the current regulatory and social environment Consumer marketing Consumer-product marketing efforts, including pricing, distribution, packaging, and ... Heart Health Center Clinical Professor Family Medicine and Health The Ohio State University Columbus, OH Corinne G Husten, M.D., M.P.H Medical Of cer Of ce of Smoking and Health Centers for Disease...

Ngày tải lên: 06/03/2014, 01:20

... services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the National ... evidenced by the steady decline in mortality in the United States since 1900, a decline only briefly interrupted by the 1918 flu pandemic And while much of the decline during the first half of the 20th ... advance the field of ­genomics and improve the translation of research findings to health care, public health, and health policy As a first step in examining issues of translation of genomic innovations,...

Ngày tải lên: 14/03/2014, 23:20

... several nuclear proteins, whereas the other is independent of the processing capacity of the proteinase and involves the HPX domain A DNA-binding domain was found in the HPX domain, as an antiMMP-3 ... result of its interaction with the N-terminal part of TIMP-2, whereas the C-terminal part of the inhibitor binds to the HPX domain of proMMP-2 Another MT1-MMP molecule can now cleave the proMMP-2 in ... domain of the a2 chain of the microfilamentous collagen VI [25] The above examples are illustrated in Fig 2B (step 1) Interactions with small integrin-binding ligand N-linked glycoprotein (SIBLING)...

Ngày tải lên: 15/03/2014, 00:20

... involved in the control of brain homeostasis, since their powerful effect on the control of cerebral perfusion will be the final determinant of the amount of oxygen and glucose delivered to the brain, ... second hand Therefore, understanding the elements of the neuronal environment and the interactions with neurons, and with each other, is crucial in understanding the development and impact of most ... explain these interactions The special status of the brain in having its own insulated circulation system — the cerebrospinal fluid contained in the ventricles and ducts — is also underlined The...

Ngày tải lên: 15/03/2014, 19:20

... overlapping with the EGF-binding domain [32] The structural constraints of the EGFR binding region support a stochiometry of : for the decorin protein core and EGFR, suggesting that decorin is ... commonality of signaling between lumican and decorin is also supported by recent studies showing the involvement of decorin in modulating various integrins in controlling proliferation, adhesion and ... lumican in the regulation of cell signaling has not been studied in great detail In analogy to decorin, lumican inhibits tumor cell growth in soft agar by increasing the expression of the cyclin-dependent...

Ngày tải lên: 15/03/2014, 23:20

... developing understanding of their significance for health and wellbeing and compared to the role of family and kinships structures in other cultures in maintaining health and wellbeing Asia and Australia’s ... years of age) 65 In these years a focus of learning should be on the further development of students‘ understanding of themselves in relation to peers, their family and others and the changing ... role in promoting and supporting the wellbeing of individuals and the community as a whole 136 Students will develop an understanding of the principles of sustainable practices when creating and...

Ngày tải lên: 22/03/2014, 15:20

Ngày tải lên: 22/03/2014, 16:20

... studies of animal models of disease and is beginning to be used in clinical investigations as a non-invasive means of monitoring disease progress and response to therapeutics Molecular imaging agents ... nanotechnology in medical applications The review was performed on the request of the Department of Pharmaceutical Affairs and Medical Technology of the Ministry of Health, Welfare and Sports in the Netherlands ... basic understanding of the origin of the unique properties of nanomaterials Therefore this report starts with a short section explaining the definitions and features of nanoscience and nanotechnology,...

Ngày tải lên: 28/05/2014, 14:35

... represented a kind of apogee of this tradition by its fusing of political and military power in the ideology of its ruling Communist Party and in the running of the state As defenders of the socialist ... controlling and guiding the defence sphere.40 The law, however, had a built -in ambiguity regarding the roles of President and Minister of Defence indicating that if the former was the dominant part of ... that the Council of Ministers ‘shall ensure the external and internal security of the state’ Thus the interim constitution maintained the ambiguous relationship between the defence minister and the...

Ngày tải lên: 04/06/2014, 00:37

... their work satisfaction, and general wellbeing The intervention is conducted in a quasi-experimental design in six nursing homes in the city of Malmö in southern Sweden The possible effects of ... provides them with opportunities to explore and master their environment and thereby become integrated in society The study is conducted in the city of Malmö in southern Sweden The possible effects of ... regarding content of the project, i.e., the role of the case manager, and her contact information The control group receives traditional care that differs from the intervention in the following...

Ngày tải lên: 10/08/2014, 10:23

... understand the role of TP in the development of pathology and in disease- specific populations including RA, cerebral palsy and TPTD Page of (page number not for citation purposes) Journal of Foot and ... [17,18] The tendon is enclosed within a synovial sheath and is held firmly in place by the flexor retinaculum which forms the roof of the tarsal tunnel The location of the TP tendon relative to the ... avoided The anterior insertion involves guiding the electrode through tibialis anterior and the interosseous membrane avoiding the deep anterior neurovascular bundle When choosing either the anterior...

Ngày tải lên: 10/08/2014, 21:23

... homogeneic mass involving the wall of the dome and two lateral walls of the urinary bladder; the average thickness of the bladder wall was 1.9 cm (Figure 1A) CT scan with three-dimensional imaging showed ... mm/h and the level of serum C-reactive protein was 3.20 g/l Serum levels of immunoglobulin (Ig)E, IgG, IgM and IgA1 were in the normal range Occurrences of the lesion in other parts of the patient's ... and can mimic those of other inflammatory and malignant bladder disorders, and cannot be distinguished Figure bladder, average thickness disclosed wall homogeneic-mass involving the wall of the...

Ngày tải lên: 11/08/2014, 17:21

... resistive inspiration significantly increased the amplitudes of the MEPgg in response to ALTMS and Cz-TMS in the OSAS patients, but not in the normal individuals In both groups the amplitudes of the ... with the AHI In other words, the more severe was the OSAS and hence the instability of the upper airway, the more responsive was the genioglossus to TMS and hence, possibly, the higher the drive ... in OSAS than in controls also with a preferential increase in UA muscles excitability during inspiratory loading in sleep apnea patients Considering the importance of the balance between UA and...

Ngày tải lên: 12/08/2014, 14:20

... region encoding the carboxy-terminal propeptide domain; H, encodes the heparin-binding domain; N, encodes the NRP1/heparin-binding domain; NP, encodes the amino-terminal propeptide domain; SP, signal ... mediated by two distinct domains In VEGF-A, these correspond to the basic heparin-binding domain encoded by exon and the NRP1/heparin-binding domain encoded by exons and [10] The nuclear magnetic ... within the cystine-knot superfamily, notably the glycoprotein hormone and mucin-like protein families and, more distantly, the transforming growth factor-␤ (TGF␤) family The absence of any of these...

Ngày tải lên: 14/08/2014, 14:21

... al 1971) The dose and duration of smoking, depth of inhalation, age of initiating smoking and type of tobacco have all been shown to influence the risk of developing bladder cancer (Steineck et ... phosphorylation of the retinoblastoma protein (Rb), thereby inhibiting the cell cycle Loss of either of these genes can result in uncontrolled growth The loss of p16, often accompanied by a loss of p15, ... seen in Trieste, Italy High incidence rates are also seen in white populations in the US, the Basque region in Spain and in Denmark The high incidence of bladder cancer seen in the Middle East and...

Ngày tải lên: 16/09/2015, 08:31