neuroanatomy primer structure and function of the human nervous system
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Ngày tải lên :
14/02/2014, 19:20
... cloned into pGEX-4T-2 The KIND domains of Spir-2 and PTPN13 were generated by RT-PCR and inserted into pEGFP-C1 and pGEX-4T-2 The N- and C-terminal regions of the v-KIND KIND2 and the MAP2 CD were ... structural and functional importance of the v-KIND and MAP2 interaction core modules in the regulation of dendrite growth and branching in hippocampal neurons and cerebellar granule cells Further studies ... proteins of these subregions (Fig S1C) and 1654 Fig Of all members of the KIND family of proteins, only KIND2 binds to MAP2 Pull-down assay (PD) of the endogenous MAP2 from cerebellar lysates of P21...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
Ngày tải lên :
06/03/2014, 11:20
... for the determination of the structures of the conformers of the C-domain The dipolar couplings provided long-distance information on the global folding of both conformers The structure of the ... on one side of the b-sheet and two on the other side The rmsd of the heavy atoms (Ca, C, and N) of the protein core, when the NMR structures of both conformers are superimposed on the crystal ... between the signal of the HN of Gly337 in the open conformer and the signal of the water protons All of these observations indicate that the loop region of the open conformer has a higher degree of...
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Báo cáo khoa học: Structure and function of the 3-carboxy-cis,cis-muconate lactonizing enzyme from the protocatechuate degradative pathway of Agrobacterium radiobacter S2 pdf
Ngày tải lên :
30/03/2014, 10:20
... in the mutant First, there is an increase in the negative charge in the active site and, second, breaking the salt bridge would alter the quaternary structure of the protein and therefore the ... in the ArCMLE1 structure The figure was created from the coordinates of the P212121 structure of ArCMLE1 and of PpCMLE (Protein Data Bank code 1RE5) (B) Water cavity below the active site The ... structure The variation in size and the observed amino acid modification between PpCMLE and ArCMLE suggested important differences between the two enzymes Therefore, the crystal structure of the...
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structure and function of the arabic verb
Ngày tải lên :
03/04/2014, 12:48
... STRUCTURE AND FUNCTION OF THE ARABIC VERB Structure and Function of the Arabic Verb is a corpus-based study that unveils the morpho-syntax and the semantics of the Arabic verb ... constructions The frequency of WA, FA-, LA-, and Ø in front of QAD Frequency of the compound perfect The distribution and frequency of sawfa/saThe frequency of QAD, laʕalla, and rubbamaa The contextual ... investigate the semantic–pragmatic functions of the second member of the opposition within the verbal system, namely the Imperfect These functions are traced out from the perspective of temporality...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
Ngày tải lên :
17/02/2014, 19:20
... empirical and theoretical work in biological oceanography and limnology that relates the structure, function and biotic composition of these systems to the body sizes of the organisms present and the ... levels of biological organization: from the life histories of individuals, to the structure and dynamics of populations and communities, to the fluxes and pools of energy and materials in ecosystems ... answered, and that the theory is fundamentally sound This volume and this chapter are on the effects of body size on the structure and dynamics of aquatic ecosystems Metabolic rate, and other rate...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
Ngày tải lên :
19/02/2014, 12:20
... subtypes, and the determination of their precise subunit composition and physiological function( s) Compared to the muscle nAChR, relatively little is known about the function and composition of the ... above, the determination of the subunit composition of the nAChRs involved has been hindered by the lack of selective ligands and imperfect correlations between the characteristics of native and ... native and heterologously expressed nAChRs The examples presented above clearly demonstrate the usefulness of a-conotoxins in the determination of the structure and function of native nAChRs, and...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
Ngày tải lên :
19/02/2014, 16:20
... Further examination of the structure and sequence of sbwAFP and TmAFP reveal other similarities (Fig 8C) The panel shows the similarity of the TXT face again, and also reveals the presence of ... changes in the structure of the insect AFPs and to further characterize the TXT face of these proteins, the backbone dynamics of TmAFP and sbwAFP were measured at 30 °C and °C [38,40] Overall, the results ... shown as smoothed, Ca traces, with the structure and PDB code shown below each panel (A) Overlap of isoform 337 with the structure of the longer isoform CfAFP-501 using the main chain of residues...
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Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx
Ngày tải lên :
16/03/2014, 16:20
... changes the conformation of the other subunit, thereby completely abolishing reaction of SDTG with the second subunit Analysis of the crystal structure of the enzyme in complex with the S-atrazine–GSH ... hydrophobic pocket of domain II of the other monomer, physically anchors the two subunits together at either end of the interface Explanation of the biphasic kinetics An average incorporation of 0.5 mol ... concentration of SDTG, k3 is the maximal rate of inactivation (min)1), and Kd is the apparent dissociation constant of the E:SDTG complex From the data shown in Fig 2, Kd values of 107.9 ± 2.1 lM and 224.5...
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Báo cáo khoa học: Structure and function of human a-lactalbumin made lethal to tumor cells (HAMLET)-type complexes pptx
Ngày tải lên :
29/03/2014, 21:20
... ago and since then the HAMLET field has widened in scope, acquiring new members and enriching our understanding of the basic principles underlying protein self-assembly and acquisition of new functionality ... radii of HAMLET (Rh = 26.9 A), which is intermediate of the hydrodynamic radii of the acidic molten globule state of a-lactalbumin ˚ (Rh = 20.9 A) and the theoretically extreme expansion state of ... describing the form and function of novel complexes such as HAMLET and ELOA, we have provided new evidence that a loss of native structure can endow proteins and their complexes with distinct and beneficial...
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Báo cáo khoa học: "Comparison between the structure and function of chloroplasts at different levels of willow canopy during a growing season" ppsx
Ngày tải lên :
09/08/2014, 03:24
... 2A) and between the ratio of the length of appressed to non-appressed thylakoid membranes and photon fluence rate (Fig 2B) This suggests that, in the canopy, acclimation of the thylakoid structure ... below 1.4 (Fig B) The leaves examined from levels and were physiologically young and the rates of C0 uptake recorded were from intermediate to high (Fig 2A) The ratio of the length of appressed to ... a lower rate of C0 uptake and an appressed/non-appressed membrane ratio of about In the present study, a tion was found between negative correla- N P and the ratio of the length of appressed...
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Báo cáo y học: " The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells" potx
Ngày tải lên :
13/08/2014, 13:20
... Background The liver sinusoids are lined by endothelial cells that have a unique structure and function essential for hepatic and systemic homeostasis Much of our understanding of the biology of the ... IM and BS conceived of the study IM carried out most of the experimental work and the writing AW and DGL participated in the determination of fenestration parameters, statistical analysis and ... static culture systems where the levels of oxygen have not been an issue Production of reactive oxygen and nitrogen species There was little expression of NO during the first 48 h of culture at...
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Báo cáo y học: "A comparative approach for the investigation of biological information processing: An examination of the structure and function of computer hard drives and DNA" doc
Ngày tải lên :
13/08/2014, 16:20
... drive (CHD) and operating system This descriptive framework is established via comparative analysis between the architecture and function of the CHD and the structure and function of eukaryotic ... the organization of these components The initial implication of this situation leads to the traditional concept of the unit of Page 20 of 29 D’Onofrio and An Theoretical Biology and Medical Modelling ... logical structures representing the organization of informational content/data of the system that is imprinted via the low-level formatting of the storage medium device The goal of this level of organization...
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Structure and function of methyltransferases from antibiotic resistance bacteroides of human intestine and a study on nm ng with cam
Ngày tải lên :
10/09/2015, 08:38
... central nervous system, the head, the neck, the chest, the abdomen, the pelvis, the skin, and the soft tissues) get infected by Bacteriodes, they can cause or exacerbate abscesses and other infections ... in the ubiquinone biosynthesis pathway The objective of this study is to understand the structure and function of these two MTases through the following experimental approaches1 To clone the ... determine the Apo and complex structures of these proteins with ligands (AdoMet/SAM and AdoHcy/SAH) using X-ray crystallography Structure function analysis to understand the role of these enzymes...
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ANALYSIS FOR STRUCTURE AND FUNCTION OF AN ECOSYSTEM HUMAN IMPACTS, CONSEQUENCES AND SOLUTIONS
Ngày tải lên :
28/05/2016, 09:28
... this area and gases from vehicles on Le Duan road HUMAN IMPACTS - CONSEQUENCES SOLUTIONS Increasing the number of wastebasket Planning the rubbish dumps and quick transporting the waste as ... penalties) for the restaurant and visitors to keep the park green, clean and beautiful CONCLUSIONS Plant species on peninsula are quite diverse People are having huge impacts on the formation and development ... Location Biotics and abiotics Energy and material flow Human impacts, consequences and solutions Conclusion LOCATION Thong Nhat Park Peninsula : 1200 m2 Including : mainland, lake, plants,...
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Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
Ngày tải lên :
14/02/2014, 18:20
... Hence, the maintenance of a condensed chromatin structure throughout the entire body of a gene may rely on the combined actions of Set3 at the 5¢ end and Set2 at the 3¢ end In yeast the cycle of ... cycle of transcription commences with the recruitment of transcription factors and co-factors bound at the promoter, which modify the local chromatin structure and enable the assembly of the pre-initiation ... bp intervals The lighter colour shades depict the bottom half of the nucleosome, and the exploded view below the octamer depicts the arrangement of the histones contacting 73 bp of DNA within...
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Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
Ngày tải lên :
19/02/2014, 07:20
... functions, and topological features retain functionality and phylogeny However, the nature of the connections between these factors needs to be understood at the level of the protein domain The ... compares the studied network with randomized versions of it with the same size and degree distribution The so-called Z-score quantifies the difference between the studied network and an ensemble of randomized ... relation to the function and structure of TFs from available information From a structural point of view, the overabundance of self-interactions is associated with a majority group of 55% of basic...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
Ngày tải lên :
19/02/2014, 12:20
... of the mature enzyme and by the ÔflapÕ The anchorage of the prosegment and of part of the N-terminus in the active site cleft is made by ionic interactions established between Lys11/Tyr13 of the ... other by three disulfide bridges A unique feature of the PSI is the swap of the N- and C-terminal portions of the saposin-like domain, where the C-terminal portion of one saposin is linked to the ... representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain, blue; C-terminal domain, red) (C) Model structure of the PSI domain of cardosin A based on the crystal structure...
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Tài liệu Báo cáo khoa học: Complete subunit sequences, structure and evolution of the 6 · 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata pptx
Ngày tải lên :
20/02/2014, 11:20
... oligonucleotides primers and the T3 vector primer The sequences were obtained after the cloning of the PCR products into the pCR4-TOPO TA vector (Invitrogen) The · 6-mer hemocyanin of S coleoptrata ... SDS/PAGE and in 2D PAGE (Figs and 2; Table 1) The N-terminal amino acid sequences (see above) allow the assignment of the HcA clone to the major sequence of the upper hemocyanin band in the SDS/PAGE ... regions and the entire 3¢ untranslated regions The standard polyadenylation signals (AATAAA) and the poly(A)-tails of different lengths are present in each clone The open reading frames of the five...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt
Ngày tải lên :
06/03/2014, 09:22
... injection of 100 lg of curdlan) and the primers listed in Table S1 The forward primer, corresponding to nucleotides 774–786 of the cDNA, also contained an NcoI restriction site The reverse primer, ... markers are indicated on the left of Spatzle-C108 (Fig 8A) Analysis of tryptic peptides ¨ from these bands by MS ⁄ MS and mascot software identified them as attacin-1, lysozyme, and cecropinA ⁄ B (Table ... yet in other insect species Although it is clear that Drosophila Spatzle acts as ¨ the ligand of the Toll receptor in two important physiological pathways [16,36], the functions of other homologs,...
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