neoglyco and neopeptide albumins for cell specific delivery of drugs to chronically diseased livers
Báo cáo y học: "Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation" pps
Ngày tải lên :
09/08/2014, 08:22
... fibroblasts and by endothelial cells (identified by von Willebrand factor staining) Page of 10 (page number not for citation purposes) Figure Autocrine activation of cortisol and the regulation of fibroblast ... dendritic cells [38], synoviocytes [39], and lymphocytes [40] Each of these different cell types appears to utilize 11β-HSD1 to atten- Figure cytokines Induction of 11β-HSD1 expression is specific for ... response to cytokine treatment Instead, striking variations in expression were observed for the enzyme 11β-HSD1, which exhibited cell- specific and cytokine -specific variations in expression and activity...
- 10
- 438
- 0
Báo cáo khoa hoc:" Biodegradable Nanoparticles are Excellent Vehicle for Site Directed in-vivo Delivery of Drugs and Vaccines" pptx
Ngày tải lên :
11/08/2014, 08:20
... drugs will get attached specifically to the tumor cells This will facilitate delivery of drugs only to the cells (tumor cells) expressing receptor and not the normal healthy cells In the pretargeting ... vaccines and drugs can be delivered into the body using nanoparticulate carriers and a number of routes of delivery NPs can be used to safely and reliably deliver hydrophilic drugs, hydrophobic drugs, ... number of biomolecules, drugs, genes and vaccines to the site of interest in-vivo During the 1980’s and 1990’s several drug delivery systems were developed to improve the efficiency of drugs and...
- 34
- 269
- 0
báo cáo khoa học: " Cell-specific expression of tryptophan decarboxylase and 10-hydroxygeraniol oxidoreductase, key genes involved in camptothecin biosynthesis in Camptotheca acuminata Decne (Nyssaceae)" ppt
Ngày tải lên :
12/08/2014, 03:21
... bp of the coding sequence and 219 bp of 3' UTR for a total of 245 bp and to 152 bp of the 5' UTR and the codon of the starting Met, for a total of 155 bp for Ca-TDC1 and Ca-TDC2, respectively ... chlorenchyma cells, yet differently from that which was found for Ca-TDC and 2, it extended to the entire mesophyll and was not restricted to specific groups of cells The different localization of Ca-HGO ... sections of leaves (B and C) and primary body of the stem (E and F), treated with Ca-TDC antisense (B and E) and sense (C and F) digoxigenin-labelled probes The square in the bottom right corner of...
- 10
- 197
- 0
Engineering scaffold and soluble cues for cell instruction
Ngày tải lên :
09/09/2015, 10:19
... provides a myriad of cues to direct organization of cellular 16 cytoskeleton, cell signaling, and function Through the study and understanding of cellECM interactions, the design of cell- instructive ... considerations To generate hydrogels scaffolds for 3D cell cultures, the hydrogels should ideally be both promoting of cellular activities and customizable to meet specific requirements of the study To bridge ... engineering Cells are harvested from donor and expanded in vitro to generate more cells These cells can then be combined with scaffolds and growth factors to form engineered tissues for implantation...
- 167
- 302
- 0
Development of hybrid promoters and viral vectors for improved gene delivery to the central nervous system
Ngày tải lên :
16/09/2015, 08:30
... applications, and were rarely used for 12 Chapter Introduction gene delivery to the CNS because of their poor in vivo performance Non-viral and viral vectors are therefore commonly used for gene delivery ... promoter and the vector, need to be optimized and combined specially for each particular application 1.2 Gene delivery to the CNS Gene delivery to the CNS, especially the brain, is drawing more and ... difficulty of gene delivery In sight of these considerations, special attention has to be paid to the gene delivery system, especially to the safety issue which is related to the vector and the...
- 138
- 340
- 0
Tài liệu Báo cáo " Effecting of medium composition on biomass and ginsenoside production in cell suspension culture of Panax vietnamensis Ha et Grushv " doc
Ngày tải lên :
12/02/2014, 10:20
... concentration of sucrose for cell growth was between 30 and 50 g/L and upto 70 g/L sucrose inhibited cell growth, while the ginsenoside content showed a steady increase with sucrose concentration of upto ... concentration of mM with nitrate alone or a (NO3 -)/(NH4 +) ratio of 2:1 In this paper, we established cell suspension culture of ginseng cell and some attempts have been made to increase biomass and ginsenoside ... health foods, drinks and cosmetics The ginseng culture has continued to attract considerable research and development effort in recent years and scientists seek to understand and optimize the culture...
- 6
- 624
- 1
Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx
Ngày tải lên :
07/03/2014, 21:20
... receptor is capable of ligand binding More surprising is the apparent differential ligand affinity of the C1 and C2 extracellular domains Expression of C1 led to the apparent sequestration of BMP-like ... decapentaplegic (DPP), screw and a third BMP ligand Gbb appear to share a common set of receptors that include the type II receptor punt and the type I receptors thick veins and saxophone (reviewed ... receptors [21] A more general phylogenetic tree was generated using a conserved kinase cytoplasmic protein sequence of all four C gigas receptors together with selected protostome and deuterostome...
- 17
- 508
- 0
Báo cáo khoa học: Optimization of an Escherichia coli system for cell-free synthesis of selectively 15N-labelled proteins for rapid analysis by NMR spectroscopy pdf
Ngày tải lên :
16/03/2014, 18:20
... concentrations of 87 and 175 lgÆmL)1 worked equally well for PpiB and hCypA Proteins produced and stored in the reaction mixture appeared to be stable with respect to proteolysis After two months of storage ... polymerase Prior to the preparation of 15N-labelled samples of hCypA and analysis by NMR spectroscopy, the performance of the cell- free expression system was explored with respect to a number of parameters ... proteolysis and mass spectrometry) to remain predominantly N-formylated due to saturation of the activity of peptide deformylase (D Mouradov and T Huber, unpublished data) In the present case of hCypA,...
- 10
- 481
- 0
Báo cáo " Effects of macro elements on biomass and ginsenoside production in cell suspension culture of Ngoc Linh ginseng " docx
Ngày tải lên :
28/03/2014, 10:20
... Results and discussion Effects of macro elements on biomass and ginsenoside production Table and Figure show how growth and yield of ginseng cell were affected by the concentrations of macro ... 1.5, and 2.0) of MgSO4 were more favorable for both cell biomass growth and ginsenoside accumulation, as seen by the highest cell biomass DW (10.4 g) and ginsenoside content (5.5 mg/g DW) Cell ... Concentration of macro-element Fig Growth yield of ginseng cell was affected by concentration of macro elements Values are the quotient of the root dry weight after weeks of culture and the cell dry...
- 5
- 568
- 0
Research Gaps and Measurement Challenges for Studying the Influence of New Media on Adolescent Sexual Health docx
Ngày tải lên :
30/03/2014, 05:20
... health and media use, and program developers This research was conducted in RAND Health, a division of the RAND Corporation A profile of RAND Health, abstracts of its publications, and ordering information ... theories were either too broad to provide these kinds of specific predictions (for example, the Theory of Reasoned Action) or were too specific to account for the variety of predictions that could ... in the area of new media use and its links to adolescent sexual health and (2) to discuss measurement and design issues with an eye to the development of valid and reliable measures of adolescent...
- 13
- 414
- 0
Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt
Ngày tải lên :
18/06/2014, 19:20
... of H9c2 Cells For the protective effect of combined pretreatment of PEP-1-SOD1 and PEP-1-CAT on H9c2 cells, cells were pretreated with or without PEP-1-SOD1 (2 μM) for h or PEP-1-CAT (2 μM) for ... 5) (B) Effect of PEP-1SOD1 and PEP-1-CAT on apoptosis of H9c2 cells under hypoxia-reoxygenation injury H9c2 cells were pretreated with PEP-1-CAT for h and/ or PEP-1-SOD1 for h The cells were then ... the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and cTnT are reliable indicators of myocardium injury [12,27] MDA can be detected at a very early time of an injury, and is...
- 11
- 349
- 0
Báo cáo hóa học: " EQ-5D visual analog scale and utility index values in individuals with diabetes and at risk for diabetes: Findings from the Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD)" potx
Ngày tải lên :
18/06/2014, 22:20
... a value of and dead a value of For this study, U.S population weights were used to convert to an EQ-5D index score [14] Statistical analysis For each group (type diabetes, high risk and low risk), ... (3.18 for VAS score and 0.009 for index score; p = 0.008) reported higher EQ-5D scores The model F statistic was 94.0 for VAS score and 83.6 for index score, and the model r-square was 0.16 for ... Dimensions; *p < 0.001 for comparison with type diabetes; ^ p < 0.0001 for comparison of high risk to low risk Page of (page number not for citation purposes) Health and Quality of Life Outcomes 2008,...
- 7
- 611
- 1
Báo cáo khoa học nông nghiệp " POST HARVEST MANAGEMENT AND NEW APPROACH FOR SUPPLY CHAIN SYSTEM OF CABBAGE AND WATER MELON " doc
Ngày tải lên :
21/06/2014, 04:20
... sample for cabbage, and total fruits per total sample for water melon III Result and discussion 3.1.Supply chain mapping for cabbage and water melon After harvesting, cabbage and water melon are often ... other and willing to work together to define common objectives, share risks and benefits and make the relationship work - Proper handling and temperature management, speed in delivery to next ... stakeholders A new approach for modern supply chain could be proposed to apply for cabbage and water melon to meet market requirement and consumer demand for higher food quality and safety: - Supply...
- 5
- 412
- 1
Báo cáo vật lý: "PREPARATION OF SELENIUM-DOPED ACTIVATED CARBON AND ITS UTILIZATION FOR IMPROVING THE QUALITY OF USED COCONUT OIL" pps
Ngày tải lên :
07/08/2014, 14:20
... temperature for 24 h, thus forming a mixture of the oil and blonde Separation between the oil and blonde was performed by centrifugation at 2000 rpm for 15 The fresh coconut oil of 2.28 l was ... MAC for 15 to 105 min.27 In addition, the propagation step leads to the formation of peroxide and hydroperoxide which are unstable, reactive Preparation of Selenium-Doped Activated Carbon 18 and ... financial support and all the facilities Special thanks are devoted to Professor Bahruddin Saad (Deputy Dean Research and Graduate Studies, School of Chemical Sciences) and Dato’ Professor Muhammad...
- 11
- 386
- 0
Báo cáo toán học: "Products of all elements in a loop and a framework for non-associative analogues of the Hall-Paige conjecture" potx
Ngày tải lên :
07/08/2014, 21:21
... combinatorial nature of the problem and generalizes more naturally to the concepts of k-plexes and regular k-plexes For H ⊆ Q and k 1, let P k (H) be the set of elements in Q that admit factorizations ... generalization of the D´nes-Hermann e theorem and provide an elementary proof of a weak form of the Hall-Paige conjecture We begin with a minimal background on the theories of latin squares and loops ... The history of Theorem 1.1 dates back at least to a result of Paige from 1951 in which he proves (1) =⇒ (3) [15] In 1955 Hall and Paige proved that for all finite groups (1) =⇒ (2) and that for solvable,...
- 15
- 298
- 0