multiscale modeling approach for studying mdh catalyzed methanol oxidation
Organ Transplantation doc
Ngày tải lên :
28/03/2014, 10:20
... administration of alemtuzumab, and it is therefore reserved for special circumstances in a select group of transplant recipients for induction immunosuppression or for the treatment of rejection episodes ... mentioned earlier, CTLA-4 has a high affinity for CD80/86 and therefore prevents the CD80/86-CD28 interaction required for costimulation, raising the threshold for activation of T cells, effectively ... HTA HUS IBMIR ICAM-1 forced expiratory flow 25–75% forced expiratory volume in second future liver remnant functional residual capacity focal segmental glomerulosclerosis forced vital capacity...
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ABC of heart failure History and epidemiology - part 1 potx
Ngày tải lên :
10/08/2014, 15:20
... studies, with the use of scores for clinical features determined from history and examination, and in most cases chest radiography, to define heart failure The Task Force on Heart Failure of the ... Study Diagnostic criteria Hillingdon heart failure study (west London) Clinical (for example, shortness of breath, effort intolerance, fluid retention), radiographic, and echocardiographic Clinical ... prescription data for loop diuretics and examination of the general practice notes of a sample of these patients, to determine the number who fulfilled predetermined criteria for heart failure...
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ABC of heart failure History and epidemiology - part 3 doc
Ngày tải lên :
10/08/2014, 15:20
... sparing diuretics Omit (or reduce) diuretics for 24 hours before first dose Advise patient to sit or lie down for 2-4 hours after first dose Start low doses (for example, captopril 6.25 mg twice daily, ... mortality Carvedilol superior to placebo for morbidity and mortality Bisoprolol superior to placebo for morbidity and mortality Metoprolol superior to placebo for morbidity and mortality Placebo groups ... exercise capacity Indeed, cardiac cachexia is an independent risk factor for mortality in patients with chronic heart failure A formal nutritional assessment should thus be considered in those patients...
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ABC of heart failure History and epidemiology - part 4 ppt
Ngày tải lên :
10/08/2014, 15:20
... no predisposing factors for heart failure for example, previous myocardial infarction, angina, hypertension, and diabetes mellitus Requiring general practitioners to perform electrocardiography ... and valvar heart disease x Arrhythmias for example, atrial fibrillation x Secondary causes for example, thyroid disease x Severe left ventricular impairment for example, ejection fraction < 20% ... myocardial infarction, sustained cardiac arrhythmias (for example, atrial fibrillation or ventricular tachycardia), or mechanical problems (for example, acute papillary muscle rupture or postinfarction...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 1 potx
Ngày tải lên :
11/08/2014, 15:20
... now confronted with large numbers of terminally ill patients for whom conventional therapies for heart failure have been exhausted and for whom repeated hospital visits are necessary There now is ... for angina or for congestive heart failure (CHF)? -\¥liat, if any, improvement m EF can be documented objectively? -What is the long-terai survival after !ow-EF CABG? Coronary Arteiy Bypass for ... appropriate guidelines for patient selection'.' The Yale Experience At Yale University, we have taken an aggressive approach by widely applying mvocardial levascularization for patients with advanced...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 2 pdf
Ngày tải lên :
11/08/2014, 15:20
... transplantation can reasonably be considered for patients with advanced ischemic cardiomyopathy Figure presents the survi\'al information from Luciani"s series in graphic form It must be borne in mind that ... (0.2 to 3.0%) at any given time is too low to account for the impairment of cardiac performance seen in heart failure Nonetheless, myocardial remodeling is initially compensatory but finally myocardial ... and actin " Therefore, * alterations in myosin light chain in heart failure may be of functional consequence for contractile activation.^'' Furthermore, an abnormal troponin-T isoform (12) is produced...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 3 doc
Ngày tải lên :
11/08/2014, 15:20
... radionuclide angiography before and after aortic valve replacement in 93 consecutive patients with chronic aortic regurgitation: open circles; patients who died before their 6-month re-evaluation ... fracUons before and after surgery (From; Bonow RO, Dodd JT, Maron BJ, et al: Long-term serial changes in left ventricular function and reversal of ventricular dilatation after valve replacement for ... whatever diastoiie dimeiisioii is achieveii at vvecks IS likely to be maintained for the next or 6: years,'' Tiierefore the eaily postoperative dclerminations are of irnportaiit prognostic significance...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 4 pot
Ngày tải lên :
11/08/2014, 15:20
... comfort and in a more favourable condition for surgery and perhaps most importantly to the larger majority of patients for whom transplantation is not an option Adjunctive Outpatient Therapies for ... al Importance of collateral circulation for prevention of left ventricular aneurysm formation in acute myocardial infarction Circulation 1989;79:791-6 Forman MB, Collins HW, Kopelman HA, et al ... ventricular dysfunction becomes 'end-stage' ^"* Approach to the Patient Referred for Cardiac Transplantation •fhe most common diagnosis in adults referred for transplantation is dilated heart failure,...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 5 pot
Ngày tải lên :
11/08/2014, 15:20
... Candidate for Cardiac Transplantation 81 acceptability have been 50-70% of predicted forced vital capacity- and forced expired volume Cessation of smoking is generally required by most programs for ... intracardiac tumours are rare indications for fransplantation Contraindications to Cardiac Transplantation Evaluation for transplantation includes a careful search for any non-cardiac condition that ... demonstrated indications for transplantation, in practice it is often more efficient to perform it simultaneously Furthermore, in patients who initially appear too well for fransplantation, but...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 6 potx
Ngày tải lên :
11/08/2014, 15:20
... of 3.6 years and 4.5 years for single and double lung, respectively For adult transplantation, there is a Significant diflcircncc companng lung transplantation performed from 1988 tliixtugli ... have intermediate survival rates Registry -oflnt 'I Soc for Heart
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 7 docx
Ngày tải lên :
11/08/2014, 15:20
... techniques arc available; pcrcutaneously (for support needed for < hrs) or via a graft sutured to the femoral arterv' or the ascending aorta (for support needed for days) The catheter is then advanced ... vanety of devices are available for supporting the failing circulation and can be classified into those used for short-term support (hours to days) and those used for longer term support (days ... Hemopump is best suited for short-term support and is thus mainly indicated for supporting patients with acute reversible myocardial dysfunction It has been successfully used for acute cardiac failure...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 9 doc
Ngày tải lên :
11/08/2014, 15:20
... diagnosis of only 1.7 years for males and 3.2 years for females Heart failure ultimately results in a slow, painfiil and costly death Therapies For centuries, therapies for this disease have been ... valve replacement for intnnsic mitral leaflet patliolog>' A De Vega tricuspid annuloplasty was performed in 33 (58%) patients and one patient required a Cosgrove-Edwai'ds ring for 4+ tricuspid ... impact of heart failure in the United States: time for a different approach J Heart Lung Transplant I994;13:S107-12 Clark AL, Coats \J New evidence for improved survival in chronic heart failure...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 10 pot
Ngày tải lên :
11/08/2014, 15:20
... supply 4) no requirement for immune suppression 5) a reduced cost for medication and 6) an improved quality of life, ' '* Another potential application for fiiture devices is for myocardial recovery ... eliminating the need for diaphragmatic perforation and extension of the incision into the abdominal area However, to achieve the goal of intrathoracic implantation, significant efforts dedicated to ... support, fiiture devices will need to be adaptive for this application While the potential for recovery of ventricular fiinction is an exciting prospect for the field of circulaton support, it is in...
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Báo cáo y học: " Isolated left ventricular non-compaction as an unusual cause of heart failure: a case report" pdf
Ngày tải lên :
11/08/2014, 21:22
... the Consultant responsible for the patient Both authors have drafted, read and approved the manuscript Consent Written informed consent was obtained from the patient for publication of this case ... ventricle Echocardiography remains the reference standard for the diagnosis of IVNC [5] Jenni and colleagues identified four criteria for the diagnosis of IVNC by echocardiography [5] A thick, ... of left ventricular myocardial compaction, although the trigger for this phenomenon is not yet known Both familial and sporadic forms of IVNC have been described and although no causative gene...
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Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"
Ngày tải lên :
05/11/2012, 11:32
... pairwise comparison was performed with a paired t-test Correlation was performed by linear regression analysis Analyses were performed using the software package “SPSS for Windows 12.0.1“ 335 quantify ... time = 101905xHR-1.23; r = 0.97, p < 0.001 for normal subjects, 187663xHR-1.38; r = 0.92 for IDCM-na patients; p < 0.001 and 174925xHR-1.38; r = 0.90 for IDCM-LBBB patients; p < 0.001 The regression ... flotation right heart catheter Resting measurements were obtained twice, once 15 before and again immediately before the exercise Peak and mean pulmonary arterial pressure (MPA) as well as mean...
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Management of chronic heart failure pptx
Ngày tải lên :
08/03/2014, 14:20
... Foundation provides a telephone information service for those seeking information on heart health issues Also provide a range of written materials offering advice and information to CHD patients and ... yet evidence for a class effect in aldosterone receptor antagonists Eplerenone can be substituted for spironolactone in patients who develop gynaecomastia The EPHESUS study, performed in post ... death and hospital admissions for heart failure when added to standard treatment (which included ACE inhibitors, ARBs, beta-blockers for at least three months before randomisation, digoxin, spironolactone,...
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báo cáo hóa học:" Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure" pot
Ngày tải lên :
18/06/2014, 15:20
... software The kits for NTproBNP (fmol/ml) were purchased from ALPCO Diagnostics, Salem, New Hampshire; for IL-6 (pg/ml) and TNFα (pg/ ml) from Assay Designs Inc., Ann Arbor, Michigan; and for sFas (pg/ml) ... Fas triggers apoptosis, whereas soluble Fas (sFas) competes with membrane-bound Fas for ligand binding, therefore reducing apoptotic signaling Procedures All treatments including milrinone dosing ... remaining in place for drug initiation and monitoring as per standard care Exclusion criteria included exposure to intravenous inotropic support within month and inability to give written informed consent...
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Báo cáo hóa học: "Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion" doc
Ngày tải lên :
18/06/2014, 16:20
... solution for patients with end-stage ICM ineligible for transplant or for those wishing to avoid immunosuppression [10] Use of axialflow LVADs in large cohorts of patients deemed unsuitable for transplantation ... experience We challenged this hybrid approach in two severely symptomatic patients suffering from ICM who were hospitalized due to recurrent pulmonary oedema on minimal effort requiring intermittent inotropic ... considered ineligible for heart transplantation due to severe co-morbidities Autologous BMSCs were collected from bilateral anterior iliac crests during the same anaesthetic for device implantation...
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