mri studies of the rehydration of intact cereal grains

... interspersed by a stimulus which deviated from the standard in the intensity of the first component and the glide direction of the second constituent The number of distinct MMN components elicited by ... 56]; these findings further support the concept of the P3 as a proxy for some element of stimulus evaluation time Evidence has accumulated describing the P300 as a cognitive routine supporting the ... and the N2b Data indicate that the P300 is involved not only in processes of working memory, but may interact with the N2b in the control of motor response to external cues Through the use of...

Ngày tải lên: 02/11/2012, 11:08

... cancelled before they ever get completed Further results indicate 52.7% of projects will cost 189% of their original estimates The cost of these failures and overruns are just the tip of the proverbial ... draw rm conclusions If we ask whether the introduction of a knowledge management system improves the quality of software, only one of the studies, from the Software Engineering Laboratory gives ... with these studies is that they are mostly lessons learned reports That is, it is the same people who have initiated the programs that evaluate them Another problem is the rather limited number of...

Ngày tải lên: 16/01/2014, 16:33

... conclusion can be made based on the lack of thermal shifts when only the bases were added, whereas the addition of PRPP led to a significant thermal shift Kinetic studies of PRTFDC1 showed that this ... product of PRPP from the crystallization solution ing 81 compounds of substrates, products and regulators of other enzymes in the human nucleotide metabolism (Table S1) The library can then be ... interacts with both O6 and N7 (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in coordinating...

Ngày tải lên: 15/02/2014, 01:20

... Here, we report the results of the structural studies of the pantoate-bound form of the N-terminal domain of E coli PS (nPS) The structure and substrate-binding interactions of E coli nPS have ... well as of the alleviation of this inhibition by another substrate of the enzyme, ATP, are presented [8,9] Results Solution properties of the N-terminal domain of PS, the C-terminal domain of PS, ... regions of the Ramachandran map [32,33] Comparison of the monomer of the substrate-free form of E coli PS [13] with the monomers of nPS in the pantoate-bound form at full occupancy indicates that the...

Ngày tải lên: 16/02/2014, 09:20

... move against the war and restricted the global trade in oil export This is still known as the Arab oil embargo.8, 9) The idea of saving energy spread throughout in the world as a result of this incident ... issue from the 1960s to early 1970s in Japan On this basis, the committee on sick house syndrome (SHS) by the Ministry of Health, Labour, and Welfare of Japan announced the guideline value of formaldehyde ... habitation The cause of the disease onset relates to a house, symptoms occur within the house, symptoms are less serious or disappear when the patient is away from the house, and when the patient...

Ngày tải lên: 17/02/2014, 22:20

... targeting to the microsomes requires the cotranslational insertion of the newly synthesized protein into the microsomal membrane, where the N-terminal hydrophobic signal sequence of the protein ... localization of intact CYP2E1 in yeast cells Because of the existing ambiguity in the literature on the nature and extent of CYP2E1 import into mitochondria, we first established the relative purity of ... the activation of cryptic mitochondria-targeting signal at the 33–44 positions of CYP1A1 [4,8,9] This endoprotease was unable to cleave the N-termini of CYP2E1 and CYP2B1 [6,12] In the case of...

Ngày tải lên: 18/02/2014, 16:20

... set of control data was obtained in the absence of the protein The data set obtained in the absence of the protein was then subtracted from the corresponding data set obtained in the presence of ... performed in the absence of the ligand The control data set obtained in the absence of the ligand was subtracted from the corresponding data set obtained in the presence of the ligand The Kd values ... subtracting the control titration data in the absence of the enzymes from the titration data in the presence of the enzymes The results of the equilibrium binding studies showed that, in comparison...

Ngày tải lên: 19/02/2014, 00:20

... phosphorylation of the wild-type Relative phosphorylation expressed as a relation of the percentage of dThd phosphorylation of the corresponding mutant is given in parentheses The substrate concentration ... illustrating the binding of the feedback inhibitor dTTP and the position of Mg2+ in the active site Mg ion that coordinates the phosphates of dTTP (Fig 3) Discussion Mutation of residues in the active site ... not show any activity must therefore be a consequence of the reactivity of the functional group and further support the hypothesis that E52 acts as an initiating base in the reaction R105 mutations...

Ngày tải lên: 19/02/2014, 02:20

... reflect the mechanism of Ca2+ switching involving the alternative binding of the C-terminal region of TnI to actin or TnC in a Ca2+dependent manner [17,19] On the other hand, the inhibitory effect of ... exhibited a band near the origin and at the middle of the gel, respectively The bands corresponding to the free rabbit or Akazara scallop TnC were found in the middle to bottom of the gels (indicated ... to the fragments in the presence (d) or absence (s) of Ca2+ The measurements were performed at 15 °C The results were expressed as a percentage of the ATPase activity obtained in the absence of...

Ngày tải lên: 20/02/2014, 01:20

... sort of stopper which closed the round aperture in the roof of the Pantheon The Pantheon stands at one corner of the Region of Pigna, and a connection between the Region, the Pantheon and the ... force, the Consulship or the Presidency of the Senate Jordan, the brother of the antipope Anacletus, obtained the office, and the violent death of the next Pope, Lucius the Second, was one of the ... that the Cenci had built themselves a fortified palace on the foundations of a part of the Theatre of Balbus, between the greater Theatre of Marcellus, then held by the Savelli, and the often...

Ngày tải lên: 20/02/2014, 09:20

... established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... illustrates the overall saddle shape of the dimeric structure and the key heparin-binding residues in the N-terminal domain held coordinately by the two subunits on the top of the hollow (Fig 1A) The ... peak of wild-type LPL The LPL in the eluate was detected by Western blot with LPL polyclonal antibody 7640 The fraction number of the high-affinity peak was the same for the wild type and the WW...

Ngày tải lên: 21/02/2014, 15:20

... sunshine of the evening, the noise of the streets, the looks of the crowd, the great minster rising half-finished in the midst of the town by the Rhine, the cries and noise and chipping of the masons; ... attending to the business of factory or counting-house under the orders of the father of the family, and to the economy of the house-under the superintendence of the mother; a manner of living at ... him the "Morte d'Arthur" of the ladies and knights of Arthur's court; of the quest of the Grail by spotless knights who were bastards and fathers of bastards; of the intrigues of Tristram of Lyoness...

Ngày tải lên: 21/02/2014, 21:20

... with the idea that these are qualities of the translations that are independent of each other Fluency was judged directly by the assessors, while adequacy was meant to assess the content of the ... gold-standard Yet, the assessments of the two aspects were often the same—readability/fluency of the sentence is important for understanding the sentence Only after the assessor has understood the sentence ... analyze the association of the features that we described above and fluency Note that the purpose of the analysis is not feature selection—all features will be used in the later experiments Rather, the...

Ngày tải lên: 22/02/2014, 02:20

... exchange (2% of the isomerization rate) of the methyl group of IPP and the (Z)-methyl group of DMAPP, and an even slower exchange (0.5% of the isomerization rate) of the olefinic hydrogen of DMAPP corresponding ... for the observed very slow exchange of the HA-hydrogen of IPP In both cases, scrambling of the label takes place within the IPP pool and the error is then transcribed into the DMAPP pool by the ... concentrations of the tritiated compound, the relative transfer of 14C-label from the cyclodiphosphate pool is always in excess of the value calculated from the original molar concentration of the two...

Ngày tải lên: 22/02/2014, 07:20

... a sample of 439.1 Table summarizes the sociodemographic and psychological characteristics of the sample at the time of the first interview The majority of the sample was White (83%; the remainder ... in the composition of social networks over time could alter the relative availability and efficiency of different types of support because of changes in the availability of certain types of ties ... may change (e.g., according to the social convoy model), both theories lead us to the hypotheses that the quality of support in networks of older adults remain the same or actually increase over...

Ngày tải lên: 06/03/2014, 15:20

... regions of the state On the other hand, only a small fraction of those claiming the tax credit take advantage of the low-interest loan Furthermore, the property-tax exemption complements the tax-credit ... marketplace The oil crises of the 1970s, the deregulation of electricity and gas markets, the ebb and flow of various conflicts in the Middle East, Y2K fears, air-quality concerns, the recognition of ... industry The purpose of the study is to assess the degree to which some of the current financialincentive programs are encouraging the installation of renewable energy systems and to clarify the key...

Ngày tải lên: 06/03/2014, 19:20

... interpretation of the data suggests that the indicated basic region of ic3 of the D2 receptor and acidic region of the C-tail of the D1 receptor might be involved in the interactions between the two ... co-expressed with the appropriate a subunit of the G protein and not in the other case Although there is discussion in the literature concerning the possibilities of photoconversion of YFP into a ... either the genetic variant of dopamine D1 (D1MUT) or the D2R3 genetic variant of the dopamine D2 receptor was present in the sample, there was no visible energy transfer, despite the presence of...

Ngày tải lên: 07/03/2014, 03:20

... interpretation of the origin of the static quenching However, judging from the binding stoichiometry together with the shape of the binding curves (Fig 3), it is safe to conclude that the quenching ... tting parameters The adequacy of the analyses was determined from the reduced weighted sum of squares of residuals, and visual inspection of the distribution of weighted residuals The general expression ... Nevertheless, the R(2/3) value in the complex with 1DR is in excellent agreement with the distance measured between the Cb atoms of both residues in the structural model of RepA [2] based on the...

Ngày tải lên: 07/03/2014, 04:20

... characteristic of the structure of the native epitope in Me2SO is the presence of a large number of electrostatic interactions, especially in the central region of the peptide The side chain of Arg78 ... perpendicular to the plane defined by the backbone of the peptide The origin of this structural orientation in Me2SO is also the strong electrostatic interactions of the side chain of Arg78 with the side ... our studies of the epitope of MBP therefore we may conclude that the conformation of epitopes of the integral protein must be affected by posttranslational modifications Docking calculations of the...

Ngày tải lên: 07/03/2014, 16:20

... of their crystal structure of Pisum sativum PSI, in which the loop of PSI-G is suggested to face the stroma The amount of PSI-G in the transformed knock-out line does not reach the level of the ... topology where the loop is in the thylakoid lumen, and the N-and C-termini face the stroma, opposite to that of PSI-K On the other hand, the second scenario implies a stromal loop, like that of PSI-K, ... integration of the subunit into the PSI complex A protein band smaller that the tagged versions of PSI-G is present in the lanes with the loop-tagged PSI, but is also seen faintly in the lanes with the...

Ngày tải lên: 07/03/2014, 21:20