mouse mammary tumor virus transcriptional control and involvement in tumorigenesis

... sequence could, in turn, result in an altered virus tropism Since, in the initial infection of human cells, we used virus obtained from the GR tumor derived cell line, we sought to determine whether ... and endogenous mouse mammary tumor virus RNA in vivo results in viral recombination and broadens the virus host range J Virol 1994, 68:5019-5026 Golovkina TV, Prakash O, Ross SR: Endogenous mouse ... determine whether such a recombination, altering virus tropism, and possibly enabling infection of human cells, had occurred We examined the newly integrated proviruses in the infected human cells for...

Ngày tải lên: 13/08/2014, 05:22

... classified mouse mammary tumors according to luminal or basal tumor subtypes Many miRNAs found in luminal tumors are expressed during normal mammary development miR-135b, miR-505 and miR-155 ... as indicated in the color key Additional file 3: Figure S3 - double-immunofluorescence staining of mouse samples for basal/myoepithelial and luminal cytokeratins Normal mammary gland and mammary ... microRNAs and EMT in mammary cells and breast cancer J Mammary Gland Biol Neoplasia 2010, 15:213-223 Ma L, Teruya-Feldstein J, Weinberg RA: Tumour invasion and metastasis initiated by microRNA-10b in...

Ngày tải lên: 09/08/2014, 23:20

... classified mouse mammary tumors according to luminal or basal tumor subtypes Many miRNAs found in luminal tumors are expressed during normal mammary development miR-135b, miR-505 and miR-155 ... as indicated in the color key Additional file 3: Figure S3 - double-immunofluorescence staining of mouse samples for basal/myoepithelial and luminal cytokeratins Normal mammary gland and mammary ... microRNAs and EMT in mammary cells and breast cancer J Mammary Gland Biol Neoplasia 2010, 15:213-223 Ma L, Teruya-Feldstein J, Weinberg RA: Tumour invasion and metastasis initiated by microRNA-10b in...

Ngày tải lên: 09/08/2014, 23:20

... with invasive carcinoma of the anal canal, 42 patients matched for TNM-stage and of these 42 patients 10 patients corresponded for age and grading After obtaining informed consent and internal institutional ... approval, clinical outcome was analyzed by reviewing medical records and interviews of patients Pre-treatment staging was performed in all patients and included digital examination, endoluminal ultrasound, ... HIV-infected individuals are confronted with a an increased risk for cancer disease, including anal carcinoma [1-4] Although HAART has favorably influenced the incidence of non-Hodgkin lymphoma and...

Ngày tải lên: 09/08/2014, 10:21

... regulated set and control set The fold change in frequency of each binding site between the regulated and control gene sets is calculated in order to find binding sites that are enriched in the regulated ... participants in a system using differential binding site search To test whether mining of DNA microarray datasets using DBSS can generate novel insights into the key transcription factors operating in ... interface of the potential binding site search Web interface of the potential binding site search (a) Web interface of potential binding site search Gene IDs can be input in the form of either gene...

Ngày tải lên: 14/08/2014, 17:22

... mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher Current printing (last digit): 10 PRINTED ... of spinal and cranial nerves in eupnea and gasping in the adult cat In upper panel, integrated activities of the phrenic nerve (Phr.), ‘‘expiratory’’ intercostal nerve (T10-11 ), and ‘‘inspiratory’’ ... VII VIII IX Introduction Definition and Etiology Control of Breathing in BPD Relationships Between Control of Heart Rate and Respiration Hypoxemia in BPD Respiration During Sleep in BPD Respiratory...

Ngày tải lên: 14/02/2014, 17:20

... changes in the cytoskeleton that may occur during the initial h window of infection We infected RPE cells with K26GFP [27], and stained cells for F-actin, using phalloidin at 30 and h postinfection, ... understand HSV-1 infection of all target cells, including RPE cells, our study provides new starting points for understanding viral pathogenesis in the retina and advancing novel therapies to control ... boxed regions in (b) and (e) are highlighted in (c) and (f) Arrows and arrowheads in (c) and (f) indicate the association of HSV-1 GFP particles with actin-stained rhodamine phalloidin (g, h) Effect...

Ngày tải lên: 18/02/2014, 14:20

... be obtained by installing corrosion spools in the pipeline itself These spools can be installed, for example, before and after inhibitor injection points 22 Advances in Corrosion Control and Materials ... contained in this publication The proceedings are opened by two keynote papers from leading experts in the understanding and control of Corrosion in Oil and Gas Production: Dr S D Kapusta, Shell International, ... chemical products, reducing costs and increasing confidence in corrosion control and, thus, safety Resistance of carbon steels to sulfide stress cracking in H2S-containing environments is critical...

Ngày tải lên: 02/04/2014, 15:46

... Immunohistochemical stain c Hemotoxylin and eosin stain ing nuclear vacuolization and cell shrinkage (Figure 4B C) To identify cell infiltrates in a moribund mouse, brain sections were immunostained using anti-CD3 ... collected in North Carolina and passaged once in mouse brain and three times in Vero cells LACV/human/ 1978 was isolated from post-mortem brain tissue collected in Wisconsin and passaged once in mouse ... brain, and spinal cord Respiratory tissue, including lung and nasal turbinates, contained virus following inoculation with 100 or LD50 beginning on days and 2, respectively CNS infection appeared...

Ngày tải lên: 20/06/2014, 01:20

... May 19 May 19 May 19 May June June 10 June 23 June Swine Swine Swine Swine Swine Swine Swine Swine Swine Swine Swine Swine Swine Bovine Swine Swine + + + + + + + + + + + + + + + a Date of Outreak ... FMD viruses from pig and cattle herds located in Anseong, Yongin, Jincheon and Pyoungteak counties of two provinces FMD virus isolated from swine clinical samples showed cytopathic effect in IB-RS-2 ... sixth and ninth day of incubation IFA using FMDV specific Mab was performed to confirm that the isolated virus was FMDV (Fig 1) A total of 15 virus isolates was obtained in this study and the viruses...

Ngày tải lên: 07/08/2014, 18:21

... sesurivaynub woh :stsinogatna norefretni dna tfihs cinegitna ,tfird cinegitnA MR ttoillE ,F rebeW 32 67-17 ,7 ,9991 loiborciM sdnerT sdoporhtra yb noissimsnart suriv ni srotpecer dna noitingoceR F kliW ... ,WD yelsaeB ,H iN ,T nomoloS 02 366-456 ,64 ,2991 gyH deM porT J mA aidnI nrehtuos ni sitilahpecne esenapaJ fo ygoloimedipe eht ni rotcaf a sa snrettap gnideef doolb otiuqsoM RT inaM ,A ananajaG ... laremehpe enivoB SB igeN ,S idnaN 41 631-721 ,21 ,2791 )oykoT( Q htlaeH minA tsnI ltaN stelgip nrobllits fo niarb eht morf suriv AND gnitanitulggameh a dna suriv sitilahpecne esenapaJ fo noitalosI...

Ngày tải lên: 07/08/2014, 20:23

... Quantification of pine and competing vegetation response to VC and fertilization applied singly or in combination is a necessary step in understanding the primary resource limitation to pine growth In the ... Studies installed on NCSFNC member company land holdings c 2602, 3901 and 4001 were thinned prior to establishment d Standard error e The hexazinone was ineffective so the imazapyr actually controlled ... research examining VC and fertilization when applied individually Pines have consistently exhibited positive growth responses to control of both herbaceous and woody competing vegetation during the...

Ngày tải lên: 08/08/2014, 01:21

... (hyperintense signal) in the cingulate gyri, insula, and temporal lobes (arrows) FLAIR (C + D; coronal view) sequences: hyperintense swollen cortex and subcortical white matter (arrows) in the ... approved the final manuscript Authors' information G.J and B.M are attending physicians in the department of hematology and oncology of the University of Ulm P.S is attending physician in the department ... transplantation: incidence and clinical significance J Infect Dis 2006, 193:68-79 Volin L, Lautenschlager I, Juvonen E, Nihtinen A, Anttila VJ, Ruutu T: Human herpesvirus antigenaemia in allogeneic...

Ngày tải lên: 12/08/2014, 04:21

... (hyperintense signal) in the cingulate gyri, insula, and temporal lobes (arrows) FLAIR (C + D; coronal view) sequences: hyperintense swollen cortex and subcortical white matter (arrows) in the ... approved the final manuscript Authors' information G.J and B.M are attending physicians in the department of hematology and oncology of the University of Ulm P.S is attending physician in the department ... transplantation: incidence and clinical significance J Infect Dis 2006, 193:68-79 Volin L, Lautenschlager I, Juvonen E, Nihtinen A, Anttila VJ, Ruutu T: Human herpesvirus antigenaemia in allogeneic...

Ngày tải lên: 12/08/2014, 04:22

... Patel V: The multitasking clinician; Decision-making and cognitive demand during and after team handoffs in emergency care International Journal of Medical Informatics 2007 in press Sampson R, ... entertain several global workspaces simultaneously, and thus raise overall action capacity while reducing, but not eliminating, inattentional blindness, although introducing failures involving miscommunication ... input and a receiver of output, but as a vehicle of thought the individual and the environment should be viewed as dynamically interacting, resulting in cognitive performance and learning Increasingly,...

Ngày tải lên: 13/08/2014, 16:21

... 9p, 6q and 5q corresponding to inactivation of TP53, RB (retinoblastoma 1), AXIN1 (axis inhibition protein 1), CDKN2A (cyclin-dependent kinase inhibitor 2A, also named p16), IGF2R (insulin-like ... of a tumor suppressor gene in solid tumors, LOH in a particular chromosomal region in a tumor may indicate the presence of a tumor suppressor gene that contributes to the tumor In HCC, tumor ... liver and liver tumors obtained from DEN-treated C3H/HeJ mice It is upregulated in both mouse and human HCC Using this mouse model, CRG-L2 was detected in 69% (311/453) of the 32-week tumors examined...

Ngày tải lên: 11/09/2015, 16:07

... these findings to true hyphal growth remains unclear 1.3.4 Septin ring and morphological control Besides the polarization of actin cables and patches in the budding yeast, septin ring, consisting ... cells, indicating that in C albicans budding from random positions is not favored In a certain perspective, it is an interesting finding because the polarized growth from random positions during ... mother cell and growing bud (Longtine and Bi, 2003) Septin ring is composed of an evolutionarily conserved family of proteins known as septins including Cdc3, Cdc10, Cdc11, and Cdc12 Septins are...

Ngày tải lên: 16/09/2015, 15:55

... factors affecting L2 motivation maintaining is parents Parents can be considered as the most important in increasing and maintaining student motivation in L2 learning According to Wlodkowski and Jaynes ... MOTIVATION IN LANGUAGE LEARNING 15 STUDIES INTO PARENTAL ATTITUDES AND INVOLVEMENT IN CHILDREN’S LANGUAGE LEARNING20 Parental attitudes in children’s language learning 20 Parental involvement in children’s ... attitudes and involvement as perceived by students 47 4.2 PARENTAL ATTITUDES AND INVOLVEMENT IN CHILDREN’S ENGLISH LEARNING JUDGED BY PARENTS 52 4.3 PARENTAL ATTITUDES AND INVOLVEMENT IN CHILDREN’S...

Ngày tải lên: 06/06/2016, 06:42

... improvement in FBS or glycated hemoglobin, but in the control group, the insulin sensitivity decreased and the fasting insulin and insulin resistance increased, which shows a protective effect in our intervention ... Instrument Ltd, United Kingdom HOMA Calculator ver 2.2 (University of Oxford) by analyzing the two parameters fasting glucose and fasting insulin: insulin sensitivity (%S) and HOMA (insulin resistance), ... hour fasting period from each subject for biochemical parameters, including fasting glucose, lipid profile, fasting insulin, HbA1C, hsCRP and total antioxidant capacity (TAC) at baseline and at...

Ngày tải lên: 22/07/2016, 08:43

... polyprotein from VV inhibits cellular and viral protein synthesis in RL+/+ and in RL-/- infected cells Expression Expression of HCV polyprotein from VV inhibits cellular and viral protein synthesis in ... cellular and viral protein synthesis in cells expressing HCV polyprotein Time-course analysis of cellular and viral protein synthesis in cells expressing HCV polyprotein A: BSC40 cells infected ... polyprotein from VV inhibits cellular and viral protein synthesis in the hepatic cell line HepG2 Figure Expression of HCV polyprotein from VV inhibits cellular and viral protein synthesis in the...

Ngày tải lên: 19/06/2014, 08:20