molecular knudsen and surface diffusion in pores
Tài liệu Báo cáo khoa học: Tachykinin-related peptide precursors in two cockroach species Molecular cloning and peptide expression in brain neurons and intestine docx
... from both brain and intestine in L maderae [14,15] The finding that N-terminally extended TKRPs are predominantly expressed only in the gut and not in the brain are in line with findings of enrichment ... receptors and invertebrate tachykinins: a review Zool Sci 20, 533–549 Pennefather, JN, Lecci A, Candenas ML, Patak E, Pinto FM & Maggi CA (2004) Tachykinins and tachykinin receptors: a growing family ... efficacy in processing of two N-terminally extended TKRPs in the brain and intestine, respectively This could result in the gut-specific accumulation of such peptides, whereas in the brain cleavage...
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Báo cáo khoa học: Molecular structures and functional relationships in clostridial neurotoxins potx
... single chain molecule The position of the binding domain of E could be obtained by rotating the binding domain of A or B about the linker region connecting the translocation and binding domains ... binding domain of BoNT ⁄ B The HCN domain has lectin binding motif and the HCC domain contains a b-trefoil fold which provides binding pockets for the receptors (1281–1314) at the C-terminus ... doxorubicin to find a potential inhibitor Unfortunately, this study has not been continued Recently, interest in the binding domain has gained momentum because the binding sites (both gangliosides and...
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Báo cáo khoa hoc:" A review on SNP and other types of molecular markers and their use in animal genetics" ppt
... families for genotyping, selecting recombination events in recurrent backcrosses, using advanced intercross lines (AIL) or performing linkage disequilibrium and haplotype-based studies in outbread populations ... just using SNPs in animal genetics 277 standard oligonucleotides in combination (in addition to restriction enzymes in the case of AFLPs), considerably reducing the effort and consumables, and therefore ... alternative 6.3 Fine QTL mapping, candidate genes and complex traits Several approaches can be taken for fine QTL mapping, such as increasing the number of meiosis events by increasing the size and/ or the...
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Báo cáo y học: "nstitute for Molecular Bioscience and ARC Centre in Bioinformatics" pptx
... ectodomain Ptpre U36758 + Ligand binding ectodomain Ptprg AK144283 + Ligand binding ectodomain Ptprs AK159320 + Ligand binding ectodomain Ptpro U37466 + Ligand binding ectodomain Rps6kc1 BC058403 + ... 2C, C-terminal Prkx AK039088 + Protein kinase c terminal domain(IPR000961) Ptpn21 D83072 + Band4.1/Ferm Ptprb AF157628 + Ligand binding ectodomain Ptprd BC025145 + Ligand binding ectodomain Ptpre ... nine novel isoforms: seven secreted forms (Epha1 in bladder, Epha7 in brain, Flt3 in spinal cord, Ptprd in hypothalamus, Ptprg in brain, eye, white fat, and lung, Ptpro in brain, and Ptprs in...
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Molecular diagnosis and mutation characterization in thalassemias
... within intervening sequence (IVS 2) and in their 3’ non-coding region Each α-globin genes contains three exons, separating by two introns, or intervening sequences They encode identical proteins, ... PTC-containing β-globin gene in cytoplasm and nucleus in the global presence of translation 111 Figure 4-11 The relative expression level of PTC-containing β-globin gene in cytoplasm and nucleus in ... nonsense mutations and chain termination mutations [9] In α-thalassemias, the defective α-globin chain synthesis cause β-globin chain in excess in RBC The degree of imbalanced globin chain synthesis...
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BORON AND PHOSPHORUS DIFFUSION IN SILICON INTERSTITIAL, VACANCY AND COMBINATION MECHANISMS
... pre-exponential, D0 , and diffusion coefficient, D, of B and P in silicon at zero pressure We also compare the calculated results for diffusion of B and P in silicon with the experimental data and the different ... self-interstitials, the impurity interstitial may the knock a silicon lattice atom into a self-interstitial position (Fig.1) Fig Vacancy, interstitial and combination machanisms For all diffusion ... 4.21 Using the experiment data for Si and impurities B and P (Table and Table2), and our theory in Section 2, we the obtain the values of activation energies Q, pre-exponential factor D0 of B and...
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BORON AND PHOSPHORUS DIFFUSION IN SILICON PRESSURE DEPENDENCE
... A) 3.79 4.21 BORON AND PHOSPHORUS DIFFUSION IN SILICON 157 Using the potential parameters for Si and impurities B and P (Tables and 2), and our theory in Section II, we obtain the values of the ... saddle point in its migration path In interpreting atomistic calculations and experiments in the past, the assumption has been made almost universally that, V m , is negligible [10] In the present ... volume changes are shown schematically in Fig Fig.1 Schematic volume changes (see dashed lines) upon point defect formation and migration for simple vacancy and interstitialcy mechanisms The formation...
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Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering
... depth-averaged model in a nonorthogonal curvilinear coordinates for prediction of flow pattern in meandering channel with 60o and 90o bend, and also with compound meandering channel In this study, ... in computational cost while maintaining the accuracy when applied to flow in a channel with linear or almost linear bottom/bed But indeed, in many cases, water flows over very irregular bed surfaces ... coordinates for predicting sea level, currents in estuarine and shelf water (Muin and Spaulding 1996) Ye and McCorquodale (1997) developed a depth-averaged model in a non-orthogonal curvilinear system...
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Tài liệu Báo cáo khoa học: Influence of modulated structural dynamics on the kinetics of a-chymotrypsin catalysis Insights through chemical glycosylation, molecular dynamics and domain motion analysis pptx
... rigid domains [domain (residues 1119) and domain (residues 151245)] linked by an interdomain hinge (residues 120150) Interestingly, the connection between the two domains and the hinge appears ... a-CT including both the spectra of the undeuterated and completely deuterated protein H D exchange kinetics were determined by following the decrease in the absorbance of the amide II band (N-H, ... the glycans to the protein surface via the lysine e-amino groups at pH and above (Table 1) The resulting conjugates are heterogeneous mixtures of noncrosslinked single protein species characterized...
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Simple Molecular Orbitals - Sigma and Pi Bonds in Molecules pot
... found in organic chemistry In these drawings a simple line indicates a bond in the plane of the paper, a wedged line indicates a bond coming out in front of the page and a dashed line indicates ... fill into our molecular orbital diagram and that would force us to fill in the bonding sigma MO and the anti-bonding sigma-star MO What we gain in the bonding sigma MO, we lose in the anti-bonding ... simple lines to indicate bonds in the plane of the page, wedges to indicate bonds extending in front of the page and dashed lines to indicate bonds extending behind the page Possible 3D drawings...
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Báo cáo khoa học: Molecular cloning and characterization of methylenedioxy bridge-forming enzymes involved in stylopine biosynthesis in Eschscholzia californica doc
... (S)-cheilanthifoline, not (S)-nandinine [7,30,31] If we assume that (S)-nandinine is produced in E californica, there may be no need for a catalyst from (S)-nandinine to (S)-stylopine However, nandinine could ... (S)-nandinine from (S)-scoulerine in vitro; indeed, CYP719A3 converted (S)-scoulerine to (S)-nandinine with high affinity (Km ¼ 0.54 lm) (Fig 6) Previous reports have shown that (S)-stylopine is ... CYP719A2, and CYP719A3 was all the highest in root, and sanguinarine is found exclusively in root (data not shown), root is likely the main organ for the biosynthesis and storage of sanguinarine in...
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Báo cáo khoa học: Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis docx
... Oncogenes and Related Genes Shanghai Cancer Institute, Shanghai, China Smith RK, Carroll PM, Allard JD & Simon MA (2000) MASK, a large ankyrin repeat and KH domain-containing protein involved in Drosophila ... variant A Fig Interaction of Vpr and VBARP proteins in vitro and in vivo (A) In vitro translated 35S-labeled VBARP-His isoforms were incubated with Vpr or Nef and immunoprecipitated using a-His (lanes ... ankyrin repeat proteins, using the consensus established by Kohl et al [10] and Mosavi et al [11], which contains ankyrin repeats from over 4000 proteins, indicated that the ankyrin repeat domains...
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Báo cáo Y học: Molecular cloning and characterization of isomultiflorenol synthase, a new triterpene synthase from Luffa cylindrica, involved in biosynthesis of bryonolic acid ppt
... A., Inoue, K., Hiraoka, N., Ikeshiro, Y., Kushiro, T., Shibuya, M & Ebizuka, Y (2001) Cloning and characterization of a cDNA encoding b-amyrin synthase involved in glycyrrhizin and soyasaponin ... into pBluescript SK(–) (Stratagene) by in vivo excision, and was sequenced in both strands by the dideoxy chaintermination method using a model 373A DNA sequencer (PE Biosystems) Nucleotide and ... Ebizuka, Y (1998) Molecular cloning of cDNA from Panax ginseng The isogene that encodes b-amyrin synthase In Towards Natural Medicine Research in the 21st Century, Excerpta Medica International Congress...
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Poisoning the Well: How the EPA is Ignoring Atrazine Contamination in Surface and Drinking Water in the Central United States pot
... Widespread Atrazine Contamination and Inadequate Regulation and Monitoring NRDC analyzed in combination for the first time—the results of surface water and drinking water monitoring required by ... eliminate the use of atrazine and control weeds while reducing their use of other dangerous chemicals Poisoning the Well: How the EPA is Ignoring Atrazine Contamination in Surface and Drinking ... Poisoning the Well: How the EPA is Ignoring Atrazine Contamination in Surface and Drinking Water in the Central United States An Atrazine Primer Atrazine is a selective herbicide...
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Báo cáo khoa học: The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties ) comparative modeling to probe the molecular basis pdf
... replacing the existing gene and giving strain FI9078 Strains FI9078 and MG1363 were grown in a L or L fermenter in chemically defined medium [31] containing 1% (w ⁄ v) glucose, at 30 °C and pH ... showing rifampicin, streptomycin and erythromycin resistance PCR and Southern blotting proved that the inactivated ldh gene from strain FI7851, marked by erythromycin resistance, had crossed into ... directly involved in catalysis are identical in the two enzymes, and NADH binding is ensured 5930 A-C A-D Fig Comparison between the interfacial surfaces of the LDH and LDHB monomers at pH and pH...
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City clusters in China: air and surface water pollution ppt
... resources and analysis of supply and demand trends in China Beijing, China: China Water and Power Press Liu CM and He XW 1996 Strategies for sustainable water resources development in China in the ... development in China Beijing, China: China Water and Power Press Qian ZY and Zhang GD (Eds) 2001 Strategic study on sustainable water resources development in China Beijing, China: China Water and Power ... Concentrations of tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT) in surface waters of the main rivers and seas in mainland China Sampling locations: (1) Dalian new shipyard; (2) Qinghuangdao coast;...
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Báo cáo khóa học: Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships ppt
... mis-sense sequence variations, in addition to in uencing protein biogenesis, also may affect the splicing efficiency by interfering with binding sites for splice modulating factors [19] Although the ... reflected in the profile of acyl-carnitines in blood and in patient cells metabolizing long-chain fatty acids [27] Not surprisingly, the severe metabolic block results in profound energy deficiency and ... folding of the variant protein is compromised Inspection of the molecular structure surrounding position 304 in the mature MCAD protein [41] indicated that the lysine at position 304 is in close...
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Liquid-Gas Relative Permeabilities in Fractures: Effectsof Flow Structures, Phase Transformation and Surface Roughness pot
... Permeabilities in Fractures: Effects of Flow Structures, Phase Transformation and Surface Roughness Chih-Ying Chen June 2005 Stanford Geothermal Program Interdisciplinary Research in Engineering and Earth ... homogeneous bubble train containing long air bubbles in a cylindrical capillary tube 102 5.2 Schematic of motion of a homogeneous bubble train containing long vapor bubbles in a cylindrical capillary ... blocking and unblocking by the other phase in the case of rough-walled fracture at small flow rates Diomampo [2001] also observed localized channel flow undergoing continuous breaking and reforming...
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Báo cáo khoa học: Molecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans docx
... serine-threonine protein kinases that includes vertebrate oxidative-responsive (OSR1) and proline-alanine-rich Ste20-related kinase (PASK; also known as SPAK) [32] GCK-VI kinases are expressed in ... Using a yeast two-hybrid screen, we identified WNK-1 as a protein that physically interacts with GCK-3 [12] WNK protein kinases are serine ⁄ threonine protein kinases that lack a conserved lysine ... suggesting that it may be involved in discriminating osmotic from other stimuli that activate OSM-9 and ⁄ or OCR-2 Although more work is needed to understand if and how OSM-9, OCR-2, ODR-3 and OSM-10...
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cell cycle control mechanisms and protocols methods in molecular biology - tim humphrey, gavin brooks
... cell cycle proteins including G1 cyclins (Cln1 and Cln2), Cdk inhibitors The Budding and Fission Yeasts 11 (Sic1, Far1, and Rum1), and replication proteins (Cdc6 and Cdc18; reviewed in ref 55) SCF ... the checkpoint sliding clamp, comprising Rad17, Ddc1, and Mec3 in S cerevisiae (Rad1, Rad9, and Hus1 in S pombe) (136–138) Both the checkpoint loading complex and the checkpoint sliding clamp ... proteins involved in the spindle checkpoint are also conserved in plants (40), including MAD2 In maize, MAD2 is abundant at kinetochores during early mitosis but is barely detectable at kinetochores...
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