models for the function of dynactin in intracellular transport

... card Finally, the respondent indicated how likely they were to experience those barriers in their life by placing them in the specified area of the chart Here, keeping the index cards on the left ... to the nearest road Karnali Highway opened in 2007, and though it is functional only during good weather, it has been instrumental in changing the life of people in the district by integrating ... to the ten themes identified in the life trajectory interviews [45, 46] The 10 themes were written on separate sheets of poster paper, and index cards were developed for the 74 sub-themes For

Ngày tải lên: 14/01/2020, 20:31

... of the work, sam- pling of data, interpretation of the data, and drafting of the arti- cle. JK contributed to the conception of the work, interpretation of the data, revision of the article for ... performed [27] (Table 3). In two populations of the case series included in the meta- analysis, there is no information on the dose in the subgroup of patients with interventions in the abdominal ... placebo. The mean estimated risk of thromboembolism of 6.42% in the eight stud- ies on the prophylaxis of bleeding was within the 95% CI of 1.2% to 31.8% determined for the case series of bleeding therapy.

Ngày tải lên: 13/08/2014, 10:20

... the retaining axial force provided by the myocardial tissues surrounding the artery distally of the cross section x = 0. In the following, we mainly consider the effect of these four forces in ... entrance cone of the bridge; F 2 is the force generated by the drag of the blood in the tun- neled segment; F 3 is due to the pressure pushing in upstream direction in the exit cone of the bridge, ... = 0 in Fig. 3). Since the ves- sel is more or less tethered to the surrounding tissues, the local wall elongations induced by this force generate in turn retaining forces in these tissues. The

Ngày tải lên: 13/08/2014, 16:21

... placebo was administered in a 100 mL bag of normal saline Addition of IV ibuprofen to the bag for dilution did not noticeably affect the volume of the infusion bag, since only a maximum of mL was ... the study to assist in maintaining the blind The study was double-blind with respect to the treatment assignment The patient, Investigator, and sponsor were blinded to the assigned treatment until ... participants in the order they were enrolled, based upon stratification The randomization block size was four The randomization block size was not revealed during the course of the study to assist in maintaining

Ngày tải lên: 13/08/2014, 21:20

... risks, the probability of an event is more appropriately estimated by the cumulative incidence function, which, for the particular event of interest, is a function of the hazards of all the competing ... forest plot representation of the effect The vertical straight line denotes null effect (odds ratio (OR) = 1) The individual points denote the OR for each study and the lines on either side the ... papers of potential interest including review papers The published text of 31 ‘randomized’ clinical trials, including seven abstracts from proceedings of scientific meetings, were further reviewed

Ngày tải lên: 13/08/2014, 21:21

... line. Thereafter, the inbreeding coefficient increased more quickly in the S line than in the C line, as could be expected, but remained moderate: the means in G12 were 0.154 and 0.068 for the ... if the female could be inseminated once instead of twice a week and if the fertility rate could be increased. The aim of the selection experiment was therefore to increase the dura- tion of fertility ... technique for mule duck production. Unfortunately, owing to the short duration of fertility in such intergeneric crossbreeding, the ducks have to be inseminated twice a week in order to maintain the

Ngày tải lên: 14/08/2014, 13:21

... greater than the softening point of the polymer. The designer should consider the softening point of the particular poly- mer used in relation to the expected service temperature. However, for a typical ... that the chemical initiator must be dissolved in the monomer prior to introducing the mixture into the concrete. In a commercial operation of almost any size, this involves storing and handling ... increases in strength are usually not as great as the increases produced by full impreg- nation. The increases in strength are a function of the depth of impregnation and the polymer loading in the

Ngày tải lên: 24/10/2014, 22:11

... leading to severe illness like ovarian cancer, which incidentally is the fourth, most common cancer in Singapore. For the better understanding of the role of xenobiotics in the progression of ... can be applied for solid samples. However they require tedious steps including mincing, shredding, grinding, pulverizing and pressurizing, to render the sample and its components into a non-viscous, ... metals in body fluids plays an important role in the disease diagnostics, since the non-biodegradable nature of most metals makes them of the most insidious pollutants. The monitoring of trace

Ngày tải lên: 10/09/2015, 09:08

... [5-8]. Therefore, determining the level of estrogens in these body fluids would be very important for the study of their roles in the carcinogenesis of ovarian and breast cancer. The role of estrogen ... numbers of clinical samples is required for a better understanding of the role of these compounds in the progression of ovarian cancer. From the results obtained using the µ-SPE technique, we infer ... numbers of clinical samples is required for a better understanding of the role of these compounds in the progression of ovarian cancer From the results obtained using the µ-SPE

Ngày tải lên: 10/09/2015, 09:08

... present in those samples. In a biplot, the length of the lines approximates the variances of the variables. The longer the line, the higher is the variance. Inferring from Figure 3.7, 3-nitroaniline ... carcinogenic forms of those amines. These derivatives stimulate tumors, usually in tissues distance from the site of administration [18]. Cooking of proteinrich foods mainly from animal origin ... important in the view that, the synergic effect of these chemicals could provide significant influence in the malignancy of the tumor. On the other hand, benign samples are greatly scattered in the

Ngày tải lên: 10/09/2015, 09:09

... min-1 and 5˚C min-1 to 320˚C (hold for 10 min). µL of the sample was injected into the GC-MS in splitless mode and the total GC-MS analysis time was 55.00 min. SIM mode employed for the set of ... using the response factor for a group congener with the same number of chlorine atoms. This is the first research work of its kind to be carried out and the method showed good linearity of the ... efficiency. Moreover for complex body fluids, it is probable that the dilution reduced the extent of interferences by the protein (clogging on the membrane) and the low viscosity of the matrix that

Ngày tải lên: 10/09/2015, 09:09

... environmental exposure [1-3]. The number of elements of interest has increased in the recent decade, not only the trace metals but the heavy metals as well. The study of the role of the trace elements has ... emphasized in the search for the possible causes of cancer. The International Agency for Research on Cancer has proposed trace elements for their carcinogenesis [4, 5]. Some of them or their compounds ... fluids. The excess levels of trace elements observed in the malignant tumor samples could either be a cause or a consequence of ovarian cancer. Regarding their role in the initiation or promotion of

Ngày tải lên: 10/09/2015, 09:09

... withdrawn into the GC syringe and the needle of the syringe was inserted into hollow fibre to about 0.2 cm of the tip of the syringe needle was covered by it. The hollow fibre was then dipped into the ... (the rest was discarded). Using the same syringe, µL of BSTFA was withdrawn, making the total volume in the GC syringe µL. The entire µL was injected into the GC-MS for injection port derivatiztion ... retained in the injection port for min). Since the injection port is heated to high temperature (300ºC) and pressurized, the holding time of would allow the estrogens and BSTFA to react. The MS interface

Ngày tải lên: 10/09/2015, 09:09

... silver staining, silver ions bind to the proteins in the gel, and are reduced to metallic silver, causing the protein bands in the gel to be visualized [21]. This method forms the basis of the Silver ... amino acids in their core. Being anionic, SDS has a negative charge over a wide pH range. Therefore, mixing the proteins in a biological sample with SDS will result in proteins having the form ... molecular mass of polypeptides. The speed of migration is dependent on the size of the ‘pores’ in the gel mesh which is in turn determined by the percentage of acrylamide present in the gel. The polyacrylamide

Ngày tải lên: 10/09/2015, 09:09

... The formation of cortical domains 1.3 Cortical domains are required for asymmetric events in the early embryo 1.3.1 The control of spindle positioning during the first mitotic division of the ... proteins are present in the NB cortex and could thus be more directly involved in the targeting or tethering of cell- fate determinants to the basal cortex Interestingly, Lgl binds ... Pins At the same time, the carboxyl terminus of Insc, containing the predicted a-helices, binds to the carboxyl terminus of Staufen (Tio et al., 1999) Insc is necessary for the asymmetric

Ngày tải lên: 15/09/2015, 17:11

... particular software implementation of a computer networking protocol suite The terms are often used interchangeably Strictly speaking, the suite is the definition of the protocols, and the stack is the ... Describe the structure of a network, including the devices and media that are necessary for successful communications Explain the function of protocols in network communications Explain the advantages ... networks 19 The Internet – A Network of Networks ISPs (Internet Service Providers) Often also TSPs Connect their customers to the Internet The Internet – ISPs connected to other ISPs 20 The Internet...

Ngày tải lên: 01/04/2014, 12:20

... Furthermore, the stochastic approach intrinsically takes account of the reduction in selection intensity as compared with the theory, of the relationships between mates and inbreeding induced in the offspring ... controlling the selected trait, in order to check the effect of linkage on the prediction of genetic variance over time in the FFM The effect of linkage was not studied in the model of Chevalet, ... elements for such a modelling In the second part, the hypothesis of an infinite number of loci controlling the selected trait was shown to be very important: similar prediction of RVI’ with L infinitesimal...

Ngày tải lên: 09/08/2014, 18:22

... 14 Effect of cooling milk on the growth of bacteria Conn[42] is inclined to regard temperature of more significance in determining the keeping quality than the original infection of the milk itself ... themselves and their excreta taint the air will often result in the absorption of these odors by the milk to such an extent as to seriously affect the flavor The custom of straining the milk in the barn ... stirring up of the same increases the number of organisms to be found in the air (Fig 11) Thus, the feeding of dry fodder and the bedding of animals with straw adds greatly to the germ life floating...

Ngày tải lên: 16/02/2014, 22:20

... regulation INCOSAI XVII asked the Working Group to examine whether further guidance on the new forms of partnership – including issues arising when the state is a minority shareholder in private businesses ... 2: Risks facing the SAI F examining the process and the results G identifying worthwhile lessons H following up their work 17 Part 2: Risks facing the SAI F Examining the process and the results ... reporting (The Role of the State as a Minority Shareholder in Privatised Businesses; paper by the Office of the Auditor General of Norway, June 2000) In Hungary the partnership agreement enables the...

Ngày tải lên: 18/02/2014, 05:20

... activity of BsArb43B Furthermore, to determine whether the role of the calcium is structural, thermal shift assays were performed to determine the Tm of the protein in the presence and absence of the ... distribution of BsArb43B in the proximity of the active site Arabinotriose in the binding cleft is represented using sticks (B) Detailed view of the binding cleft with arabinotriose (C) Details of the ... arabinohexose [15], this loop makes the reducing end of the carbohydrate chain bend towards the solvent, probably optimizing binding of the carbohydrate chain in the cleft, and resulting in trioses...

Ngày tải lên: 15/03/2014, 23:20