microsphere a novel drug delivery system

Development and evaluation of a novel nanoparticulate delivery system of arsenic sulfides

Ngày tải lên : 11/09/2015, 16:03

... Indigo Naturalis tablets ( 复方青黛片 ) containing realgar, baphicanthus cusia, radix salviae mithiorrhyzae, radix pseudosatellariae, and pulverata levis to treat APL, achieving high CR rates [Huang ... treatment phase Mean age at diagnosis is about 40 years The male to female ratio is balanced [Groopman J and Ellman L, 1979] APL is characterized by rapid accumulation of immature granulocytes called ... asthma, rheumatism, haemorrhoids, cough, and pruritus, and are also prescribed as a health tonic, analgesic, anti-inflammatory agent, and as a treatment for some malignant tumors [Pan B et al., 2004]...

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Development of novel drug delivery system lipid microemulsion of tributyrin

Ngày tải lên : 16/09/2015, 08:30

... Propofol Anaesthetic Astra Zeneca Worldwide Intralipid N A Parenteral Nutrition Pharmacia & Upjohn US and Canada Limethason Dexamethasone Steroid Palmitate Liple Alprostadil Mitsubishi Japan Pharmaceutical ... of Symbols AUC: area under the curve; CL: total clearance; CL/F: appatent total clearance; Cmax: maximal plasma concentration; F: bioavailability; Ka: first-order absorption rate constant; Ke: ... TABLE 1-4 Examples of commercially available injectable lipid submicro-emulsions Trade Name Drug Indication Manufacturer Market Diazemuls Diazepam Sedative Pharmacia & Upjohn Worldwide Diprivan...

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Drug Delivery Systems

Ngày tải lên : 25/10/2013, 08:20

... important to note that the exact period of time for degradation and erosion is not stated exactly because there are competing physical factors that can greatly accelerate or retard biodegradation A ... the ability to control drug release kinetics via changes in surface area of the delivery system For PLGA systems, the relationship between polymer degradation, drug release, and surface area is ... retarded diffusion that accelerates as the PLGA component degrades For example, ReGel has been used to release an anticancer agent, paclitaxel, for approximately 50 days [40] 15.6.7 Peptide-Based...

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Tài liệu Báo cáo khoa học: A novel electron transport system for thermostable CYP175A1 from Thermus thermophilus HB27 doc

Ngày tải lên : 18/02/2014, 08:20

... 277 283 TSIPGVYACGDIVTYPGKLPLIVLGFGEAAIAANHAAAYAN-PALKVNPGHSSEKAAPGT TSIPGVFAAGDVMDHI YRQAITSAGTGCMAALDAERYLD GLADAK TSIPGIFAAGDCTSMWPGFRQVVTAAAMGAVAAYSAYTYLQEKGLYKPKPLTGLK *****::*.** : ... Toyobo (Osaka, Japan) Emulgen 911 was a gift from Kao Chemical (Tokyo, Japan) NADPH, NADH and NADP+ were purchased from Oriental Yeast (Tokyo, Japan) a- Cyano-4-hydroxycinnamic acid was obtained from ... :.:: : * : * NAYTAKAVIIAAGVGAFEPRRIGAPGEREFEGRGVYYAVKSKA-EFQGK-RVLIVGGGDS -EYTCDALIIATGASA -RYLGLPSEEAFKGRGVSACATCDG-FFYRNQKVAVIGGGNT LEVKARTVILAVGSRR -RKLGVPGEAELAGRGVSYCSVCDAPLFKGKDAVVVVGGGDS...

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Chemical Aspects of Drug Delivery Systems pptx

Ngày tải lên : 28/03/2014, 10:20

... Materials and Systems for Drug Delivery and Targeting Table Externally activated drug delivery systems EXTERNAL ACTIVATION FORMULATION SYSTEM MECHANISM FOR DRUG DELIVERY CONTROL HEAT LIPOSOMES CHANGE ... characteristics of the targets, including access and location, as well as the characteristics of any carrier materials incorporated into drug delivery systems 4 DRUG LEAKAGE+ +NON TARGET +METABOLISM ... drug delivery and targeting - route of administration, Figure carrier and target (adaptedfrom Florence4) CARRIER SYSTEMS In many cases, carrier materials are used in particulate forms, and Table...

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THE CHEMISTRY OF DRUG DELIVERY SYSTEMS (hoá học các hệ dẫn truyền thuốc)

Ngày tải lên : 18/04/2014, 15:37

... be achieve, patient and disease GLOBAL DRUG DELIVERY MARKET BY ADMINISTRATION MODE Nasal 2% Ocular 2% Injectable/ Implant 3% Transdermal 8% Inhalation 32% Oral 53% CLASSIFICATION OF DRUG DELIVERY ... first-pass effect of drug cleareance ORAL MUCOSAL ROUTE Classification:  Sublingual delivery  Buccal delivery  Local delivery Sublingual delivery Buccal delivery Surface area: 100 cm2 Local delivery ... SUBLINGUAL AND BUCCAL DELIVERY Sublingual delivery Buccal delivery High permeability Less permeability Higher rate of absorption Low rate of absorption Higher drug bioavailability Low drug bioavailability...

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nanoparticulate drug delivery systems, 2007, p.382

Ngày tải lên : 04/06/2014, 14:47

... Formulation Characteristics 291 Jaspreet K Vasir and Vinod Labhasetwar 19 Gastrointestinal Applications of Nanoparticulate Drug- Delivery Systems 305 Maria Rosa Gasco 20 Nanoparticles as Adjuvant-Vectors ... Jerusalem, Jerusalem, Israel Juan M Irache Department of Pharmacy and Pharmaceutical Technology, University of Navarra, Pamplona, Spain K K Jain Jain PharmaBiotech, Basel, Switzerland Ashwath Jayagopal ... Lukyanov AN, Gao A, Papahadjopoulos B Immunomicelles: targeted pharmaceutical carriers for poorly soluble drugs Proc Natl Acad Sci USA 2003; 100:6039 Kabanov AV, Batrakova EV, Alakhov VY An essential...

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Báo cáo sinh học: "Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma" doc

Ngày tải lên : 18/06/2014, 19:20

... of apoptosis Cancer Gene Ther 2010, 17:212-222 Morikawa T, Sugiyama A, Kume H, Ota S, Kashima T, Tomita K, Kitamura T, Kodama T, Fukayama M, Aburatani H: Identification of Toll-like receptor as ... physic-chemical properties (size and charge) of each separate material, including PCFC-g-PEI and FA-PEAs, as well as the FA-PEAs: pVHL complexes Because PCFC-g-PEI and FA-PEAs are amphiphilic ... cationic HPEI nanogel was conjugated by 2-kD PEI and heparin Heparin is a biodegradable negative polysaccharide with many carboxylic groups, and PEI is a cationic polymer with many primary amine...

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Báo cáo hóa học: " Nanotechnology-based drug delivery systems" pdf

Ngày tải lên : 20/06/2014, 00:20

... Polyalkylcyanoacrylates (PACA) nanoparticles have been used as a carrier for targeting antileishmanial drugs into macrophages This nanomaterial did not induce interleukin-1 release by macrophages ... of the encapsulated therapeutic agent nanomaterials Polylactic/glycolic acid (PLGA) and polylactic acid (PLA) based nanoparticles have been formulated to encapsulate dexamethasone, a glucocorticoid ... potential pharmaceutical targets in many human and animal diseases Although macrophages are capable of killing most of the microbes, many microorganisms (Toxoplasma gondii, Leishmania sp, Mycobacterium...

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báo cáo hóa học: " Reduced inclination of cervical spine in a novel notebook screen system - implications for rehabilitation" docx

Ngày tải lên : 20/06/2014, 00:20

... performed the analysis and interpretation of the data MFS, SU, KV, SM, BK: Participation in the analysis of data, revision of the manuscript All authors read and approved the final manuscript Received: ... musculoskeletal disease a global perspective Clinical rheumatology 2006, 25:778-781 Kambin P, Abda S, Kurpicki F: Intradiskal pressure and volume recording: evaluation of normal and abnormal cervical disks ... results a photo digital overlay Figure Study set-up The workstation with adjustable ergonomic chair and desk as well as the adaptable protractor are displayed Gender influence on cervical inclination...

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báo cáo hóa học:" Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma" pot

Ngày tải lên : 20/06/2014, 03:20

... of apoptosis Cancer Gene Ther 2010, 17:212-222 Morikawa T, Sugiyama A, Kume H, Ota S, Kashima T, Tomita K, Kitamura T, Kodama T, Fukayama M, Aburatani H: Identification of Toll-like receptor as ... physic-chemical properties (size and charge) of each separate material, including PCFC-g-PEI and FA-PEAs, as well as the FA-PEAs: pVHL complexes Because PCFC-g-PEI and FA-PEAs are amphiphilic ... cationic HPEI nanogel was conjugated by 2-kD PEI and heparin Heparin is a biodegradable negative polysaccharide with many carboxylic groups, and PEI is a cationic polymer with many primary amine...

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Báo cáo hóa học: " The application of carbon nanotubes in target drug delivery systems for cancer therapies" docx

Ngày tải lên : 20/06/2014, 22:20

... Allen BL, Conroy J, Volkov Vlasova Y, Belikova NA, Yanamala N, Kapralov A, Tyurina YY, Shi J, Kisin ER, Murray AR, Franks J, Stolz D, Gou P, Klein-Seetharaman J, Fadeel B, Star A, Shvedova AA: ... M, Yamamoto M, Hashiba M, Mizuguchi Y, Lee BW, Kuroda E, Shimada M, Wang WN, Yamamoto K, Fujita K, Endoh S, Uchida K, Kobayashi N, Mizuno K, Inada M, Tao H, Nakazato T, Nakanishi J, Tanaka I: ... Solubilization of single-wall carbon nanotubes by supramolecular encapsulation of helical amylose J Am Chem Soc 2003, 125:4426-4427 Numata M, Asai M, Kaneko K, Bae AH, Hasegawa T, Sakurai K, Shinkai...

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Báo cáo hóa học: " Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Leve" pptx

Ngày tải lên : 22/06/2014, 00:20

... alginate as drug reservoir embedded into the platform Among polymers, alginate has several unique properties that have allowed it to be used as a matrix for the entrapment and/or delivery of a variety ... pure argon as sputtering gas) CNT Array: Properties, Imaging and Coating Alginate Thin Film Design, Production and Characterization Vertically aligned CNT arrays were provided from NanoLab, Inc ... behaviour at the neuronal interface Finally, CNT-based interfaces, as demonstrated, could be used for controlled drug delivery: any bioactive factor could be released in a spatially and temporally...

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Báo cáo y học: "Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations" ppt

Ngày tải lên : 09/08/2014, 06:23

... the ELISA experiments and participated in analysis of data CA performed the statistical analysis and the clinical associations AS participated in the analysis and interpretation of data and in ... study, participated in its design and coordination, and drafted the manuscript All authors read and approved the final manuscript Acknowledgements An association between serum AECAs and psychosis ... Psychiatric Association; 1994 14 Margutti P, Delunardo F, Sorice M, Valesini G, Alessandri C, Capoano R, Profumo E, Siracusano A, Salvati B, Rigano R, et al.: Screening of a HUAEC cDNA library...

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