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micrornas transforming growth factor beta1 and tissue fibrosis

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báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot

Hóa học - Dầu khí

... steatohepatitis and 36 with chronic hepatitis C. All had a biopsy-proven diagnosis.Measurements: Serum concentrations of transforming growth factor- beta1 and ferritin.Results: High concentrations of transforming ... (NASH) and also of the severityof fibrosis in NASH. J Gastroenterol 2007, 42:573-82.16. Khan R, Sheppard R: Fibrosis in heart disease: understandingthe role of transforming growth factor- beta1 ... values and similar in the three groups (P = 0.9), also when adjusted for gender (P = 0.5) and age (P = 0.3).Conclusion: No difference between serum concentrations of transforming growth factor- beta1...
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Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx

Báo cáo khoa học

... the data and helped to draft the manuscript. YAobtained consent from patients and collected the samples and patient data for the study, and participated in the coordinationof the study and writing ... articleActivation of transforming growth factor- β1 and early atherosclerosis in systemic lupus erythematosusMichelle Jackson1, Yasmeen Ahmad2, Ian N Bruce2, Beatrice Coupes1 and Paul EC Brenchley11Renal ... calculated low-density lipoprotein levels and increasedcarotid IMT, and may contribute to the development of earlyatherosclerosis.Introduction Transforming growth factor (TGF)-β1 is the most potent...
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Báo cáo y học: "β Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases" potx

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... additional factors and/ or cofactors thatsecondarily contribute to their function and that maybecome prevalent in the absence of TGF-β and/ or if TGF-βis dysregulated. The identification and intersection ... CD4+CD25+regulatory T cells canmediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J ExpMed 2002, 196:237-246.12. Chen W, Jin W, Hardegen ... infections and autoimmune diseases. Theirmode of suppression is contact-dependent, antigen-nonspecific and involves a nonredundant contribution from the cytokine transforming growth factor (TGF)-β....
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Báo cáo y học: " Aging, osteoarthritis and transforming growth factor-β signaling in cartilage" pps

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... this disease,which includes pathophysiology and joint stability includingbiomechanics. The balance between anabolic morphogens and growth factors and catabolic cytokines is at the crux of the ... and 7). TheCommentaryAging, osteoarthritis and transforming growth factor- ββsignalingin cartilageA Hari ReddiLawrence J Ellison Center for Tissue Regeneration, University of California, ... cells and extra-cellular matrix by anabolic morphogens and catabolic cyto-kines [1]. The aim of this commentary is to place in context arecent article in this journal of anabolic growth factor, ...
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Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot

Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot

Báo cáo khoa học

... & Colicelli J (2008) Integration of transforming growth factor beta and RAS signalingsilences a RAB5 guanine nucleotide exchange factor and enhances growth factor- directed cell migration.Mol ... during transforming growth factor- beta-induced smooth muscle differentiation. J BiolChem 281, 1765–1770.143 Deaton RA, Su C, Valencia TG & Grant SR (2005) Transforming growth factor- beta1- induced ... PRK2 and p38 MAPK and the transcriptionalupregulation of smooth muscle-specific genes such asa-SMA, SM-MHC and SM-22a via the cooperation ofserum response factor, GATA and myosin enhancerfactor...
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Báo cáo khoa học: Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor–factor VIIa–factor Xa–tissue factor pathway inhibitor pptx

Báo cáo khoa học: Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor–factor VIIa–factor Xa–tissue factor pathway inhibitor pptx

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... 270) Ó FEBS 2003 Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor factor VIIa factor Xa tissue factor pathway inhibitorKarin Carlsson1, Per-Ola ... formation between factor VIIa (FVIIa) and itscofactor tissue factor (TF) triggers blood coagulation. TheTF–FVIIa complex activates factor X (FX) to factor Xa(FXa) and factor IX (FIX) to factor IXa ... complexbetween factor VIIa (FVIIa) and its cofactor, tissue factor (TF). TF–FVIIa is inhibited by tissue factor pathwayinhibitor (TFPI) in two steps: first TFPI is bound to theactive site of factor...
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Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc

Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc

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... lipopolysaccharide-inducedtumour necrosis factor- a production by transforming growth factor- b1Tarnjit K. Khera1, Andrew D. Dick1,2 and Lindsay B. Nicholson1,21 Department of Cellular and Molecular Medicine, ... anti-inflammatorycytokine transforming growth factor- b1 (TGF-b1) ofthe proinflammatory cytokine TNF-a via the inductionof FXR1 is the focus of this article.TGF-b1, a member of the large transforming growth factor- b ... of interferon-gamma (IFN-gamma), IL-10,IL-12 and transforming growth factor- beta (TGF-beta) mRNA in synovial fluid cells from patients inthe early and late phases of rheumatoid arthritis(RA)....
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Báo cáo y học: Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-b ppt

Báo cáo y học: Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-b ppt

Báo cáo khoa học

... arylhydrocarbonreceptor expression by transforming growth factor- b1. Mol.Pharmacol. 59, 716 724.22. Doăhr, O. & Abel, J. (1997) Transforming growth factor- beta 1coregulates mRNA expression ... Nature 394, 909–913.28. Roberts, A.B. & Sporn, M.B. (1990) The transforming growth factor- bs. In Peptide Growth Factors and Their Receptors I (Sporn,M.B. & Roberts, A.B., eds), pp. 419–472. ... W. (1998)Identification and functional characterization of a Smad bindingelement (SBE) in the JunB promoter that acts as a transforming growth factor- beta, activin, and bone morphogenetic protein-inducible...
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transforming growth factor-beta protocols

transforming growth factor-beta protocols

Sinh học

... 142: Transforming Growth Factor- ` ProtocolsEdited by: P. H. Howe â Humana Press Inc., Totowa, NJDetection of TGF-` in Body Fluids and TissuesAndrew H. LimperIntroduction Transforming growth ... D., Moses, H. L., and Holley, R. W. (1984) Growth inhibitor from BSC-1 cells closely related to platelet type ` transforming growth factor. Science 226, 705–707.41. Kojima, S. and Rifkin, D. B. ... the cellular receptor for transforming growth factor type `. Biochemistry 25,3083–3091.3. Massagué, J. (1987) Identification of receptors for type-` transforming growth factor. Methods Enzymol....
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báo cáo hóa học: " Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised" potx

Hóa học - Dầu khí

... proliferator-activatedreceptor γ ; TGF-β1, transforming growth factor β1, TZD,thiazolidinedione.Competing interestsGary Landreth received a honorarium for a talk given toTakeda North America in 2003, and received fundingfrom ... westernblots and development of the morphometric method toquantitate microglia activation; GL and MH organized and paid for the synthesis and delivery of the chow con-taining pioglitazone and ibuprofen. ... patho-genesis and effects on the ageing and Alzheimer brain. NeurolRes 2003, 25:611-616.44. Wyss-Coray T, Lin C, Sanan DA, Mucke L, Masliah E: Chronic over-production of transforming growth factor...
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báo cáo hóa học:

báo cáo hóa học: " Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients" pot

Toán học

... Prabhakar†, Chandrika Abburi, Neel K Sharma and Akshay Anand*AbstractBackground: We have earlier shown that protein levels of vascular endothelial growth factor- A (VEGF-A) and chemokine ligand-2 (CCL2) ... endothelial growth factor- A (VEGF-A) is adimeric secreted polypeptide that was discovered first inthe VEGF family which also includes placental growth factor (PLGF), VEGF-B, VEGF-C, VEGF-D and VEGF-E.VEGF-A ... endothelial growth factor mRNA and downregulates its expression. J Neurosci 2007, 30:7929-38.16. Lambrechts D, Storkebaum E, Morimoto M, Del-Favero J, Desmet F,Marklund SL, Wyns S, Thijs V, Andersson...
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Báo cáo y học: "Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees" potx

Báo cáo khoa học

... AF:Cloning and sequence analysis of simian transforming growth factor- beta cDNA. DNA 1987, 6:239-244.5. Miller DA, Pelton RW, Derynck R, Moses HL: Transforming growth factor- beta. A family of growth ... problems and prospects.Cell Regulat 1990, 1:875-882.2. Roberts AB, Sporn MB: Physiological actions and clinicalapplications of transforming growth factor- beta (TGF-beta). Growth Factors 1993, ... Transforming growth factor- beta. Mul-tiple actions and potential clinical applications. JAMA 1989,262:938-941.7. Beck SL, Chen TL, Mikalauski P, Ammann AJ: Recombinanthuman transforming growth...
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