micrornas transforming growth factor beta1 and tissue fibrosis
báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot
... steatohepatitis and 36 with chronic hepatitis C. All had a biopsy-proven diagnosis. Measurements: Serum concentrations of transforming growth factor- beta1 and ferritin. Results: High concentrations of transforming ... (NASH) and also of the severity of fibrosis in NASH. J Gastroenterol 2007, 42:573-82. 16. Khan R, Sheppard R: Fibrosis in heart disease: understanding the role of transforming growth factor- beta 1 ... values and similar in the three groups (P = 0.9), also when adjusted for gender (P = 0.5) and age (P = 0.3). Conclusion: No difference between serum concentrations of transforming growth factor- beta1...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx
... the data and helped to draft the manuscript. YA obtained consent from patients and collected the samples and patient data for the study, and participated in the coordination of the study and writing ... article Activation of transforming growth factor- β 1 and early atherosclerosis in systemic lupus erythematosus Michelle Jackson 1 , Yasmeen Ahmad 2 , Ian N Bruce 2 , Beatrice Coupes 1 and Paul EC Brenchley 1 1 Renal ... calculated low-density lipoprotein levels and increased carotid IMT, and may contribute to the development of early atherosclerosis. Introduction Transforming growth factor (TGF)-β 1 is the most potent...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "β Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases" potx
... additional factors and/ or cofactors that secondarily contribute to their function and that may become prevalent in the absence of TGF-β and/ or if TGF-β is dysregulated. The identification and intersection ... CD4 + CD25 + regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J Exp Med 2002, 196:237-246. 12. Chen W, Jin W, Hardegen ... infections and autoimmune diseases. Their mode of suppression is contact-dependent, antigen-nonspecific and involves a nonredundant contribution from the cytokine transforming growth factor (TGF)-β....
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: " Aging, osteoarthritis and transforming growth factor-β signaling in cartilage" pps
... this disease, which includes pathophysiology and joint stability including biomechanics. The balance between anabolic morphogens and growth factors and catabolic cytokines is at the crux of the ... and 7). The Commentary Aging, osteoarthritis and transforming growth factor- ββ signaling in cartilage A Hari Reddi Lawrence J Ellison Center for Tissue Regeneration, University of California, ... cells and extra- cellular matrix by anabolic morphogens and catabolic cyto- kines [1]. The aim of this commentary is to place in context a recent article in this journal of anabolic growth factor, ...
Ngày tải lên: 09/08/2014, 07:20
Association between transforming growth factor b1 polymorphisms and atrial fibrillation in essential hypertensive subjects pptx
Ngày tải lên: 10/08/2014, 05:21
báo cáo khoa học: " Effects of enamel matrix derivative and transforming growth factor-b1 on human osteoblastic cells" pot
Ngày tải lên: 11/08/2014, 20:21
Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot
... & Colicelli J (2008) Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor- directed cell migration. Mol ... during transforming growth factor- beta-induced smooth muscle differentiation. J Biol Chem 281, 1765–1770. 143 Deaton RA, Su C, Valencia TG & Grant SR (2005) Transforming growth factor- beta1- induced ... PRK2 and p38 MAPK and the transcriptional upregulation of smooth muscle-specific genes such as a-SMA, SM-MHC and SM-22a via the cooperation of serum response factor, GATA and myosin enhancer factor...
Ngày tải lên: 07/03/2014, 01:20
Báo cáo khoa học: Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor–factor VIIa–factor Xa–tissue factor pathway inhibitor pptx
... 270) Ó FEBS 2003 Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor factor VIIa factor Xa tissue factor pathway inhibitor Karin Carlsson 1 , Per-Ola ... formation between factor VIIa (FVIIa) and its cofactor tissue factor (TF) triggers blood coagulation. The TF–FVIIa complex activates factor X (FX) to factor Xa (FXa) and factor IX (FIX) to factor IXa ... complex between factor VIIa (FVIIa) and its cofactor, tissue factor (TF). TF–FVIIa is inhibited by tissue factor pathway inhibitor (TFPI) in two steps: first TFPI is bound to the active site of factor...
Ngày tải lên: 17/03/2014, 03:20
Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc
... lipopolysaccharide-induced tumour necrosis factor- a production by transforming growth factor- b1 Tarnjit K. Khera 1 , Andrew D. Dick 1,2 and Lindsay B. Nicholson 1,2 1 Department of Cellular and Molecular Medicine, ... anti-inflammatory cytokine transforming growth factor- b1 (TGF-b1) of the proinflammatory cytokine TNF-a via the induction of FXR1 is the focus of this article. TGF-b1, a member of the large transforming growth factor- b ... of interferon-gamma (IFN-gamma), IL-10, IL-12 and transforming growth factor- beta (TGF- beta) mRNA in synovial fluid cells from patients in the early and late phases of rheumatoid arthritis (RA)....
Ngày tải lên: 22/03/2014, 21:21
Báo cáo y học: Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-b ppt
... arylhydrocarbon receptor expression by transforming growth factor- b 1 . Mol. Pharmacol. 59, 716 724. 22. Do ă hr, O. & Abel, J. (1997) Transforming growth factor- beta 1 coregulates mRNA expression ... Nature 394, 909–913. 28. Roberts, A.B. & Sporn, M.B. (1990) The transforming growth factor- bs. In Peptide Growth Factors and Their Receptors I (Sporn, M.B. & Roberts, A.B., eds), pp. 419–472. ... W. (1998) Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor- beta, activin, and bone morphogenetic protein- inducible...
Ngày tải lên: 31/03/2014, 23:20
transforming growth factor-beta protocols
... 142: Transforming Growth Factor- ` Protocols Edited by: P. H. Howe â Humana Press Inc., Totowa, NJ Detection of TGF-` in Body Fluids and Tissues Andrew H. Limper Introduction Transforming growth ... D., Moses, H. L., and Holley, R. W. (1984) Growth inhibitor from BSC-1 cells closely related to platelet type ` transforming growth factor. Science 226, 705–707. 41. Kojima, S. and Rifkin, D. B. ... the cellular receptor for transforming growth factor type `. Biochemistry 25, 3083–3091. 3. Massagué, J. (1987) Identification of receptors for type-` transforming growth factor. Methods Enzymol....
Ngày tải lên: 11/04/2014, 07:14
báo cáo hóa học: " Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised" potx
... proliferator-activated receptor γ ; TGF-β1, transforming growth factor β1, TZD, thiazolidinedione. Competing interests Gary Landreth received a honorarium for a talk given to Takeda North America in 2003, and received funding from ... western blots and development of the morphometric method to quantitate microglia activation; GL and MH organized and paid for the synthesis and delivery of the chow con- taining pioglitazone and ibuprofen. ... patho- genesis and effects on the ageing and Alzheimer brain. Neurol Res 2003, 25:611-616. 44. Wyss-Coray T, Lin C, Sanan DA, Mucke L, Masliah E: Chronic over- production of transforming growth factor...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients" pot
... Prabhakar † , Chandrika Abburi, Neel K Sharma and Akshay Anand * Abstract Background: We have earlier shown that protein levels of vascular endothelial growth factor- A (VEGF-A) and chemokine ligand-2 (CCL2) ... endothelial growth factor- A (VEGF-A) is a dimeric secreted polypeptide that was discovered first in the VEGF family which also includes placental growth factor (PLGF), VEGF-B, VEGF-C, VEGF-D and VEGF-E. VEGF-A ... endothelial growth factor mRNA and downregulates its expression. J Neurosci 2007, 30:7929-38. 16. Lambrechts D, Storkebaum E, Morimoto M, Del-Favero J, Desmet F, Marklund SL, Wyns S, Thijs V, Andersson...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees" potx
... AF: Cloning and sequence analysis of simian transforming growth factor- beta cDNA. DNA 1987, 6:239-244. 5. Miller DA, Pelton RW, Derynck R, Moses HL: Transforming growth factor- beta. A family of growth ... problems and prospects. Cell Regulat 1990, 1:875-882. 2. Roberts AB, Sporn MB: Physiological actions and clinical applications of transforming growth factor- beta (TGF-beta). Growth Factors 1993, ... Transforming growth factor- beta. Mul- tiple actions and potential clinical applications. JAMA 1989, 262:938-941. 7. Beck SL, Chen TL, Mikalauski P, Ammann AJ: Recombinant human transforming growth...
Ngày tải lên: 09/08/2014, 01:21