metastatic small cell carcinoma of the lung symptoms

... view of the small cell carcinoma showing hyperchromatic nuclei, nuclear moulding and clumping of the nuclear chromatin keeping with a neuroendocrine carcinoma of small cell type In the absence of ... therefore it is unclear whether her family history of lung cancer had a causative role either Figure hyperchromatic view ing of the showing4 nuclear chromatin of the small cell carcinoma High-power ... nature of the disease Therapeutic modalities are determined by the location and extent of disease Chemotherapy remains the treatment of choice The role of radiotherapy and sur- Page of (page number...

Ngày tải lên: 09/08/2014, 07:21

... contrast, most of the other studies based their analyses on patients with BC or large cell carcinoma Conclusions Although there is a low incidence of basaloid squamous cell carcinoma of the lung, it ... that were in line with the diagnostic criteria of basaloid squamous cell carcinoma of the lung, and were reclassified as basaloid squamous cell carcinoma Consequently, a total of 120 pathological ... http://www.cardiothoracicsurgery.org/content/6/1/10 Page of Figure The actual survival time of basaloid squamous cell carcinoma and PDSC patients in stage I and stage II, p = 0.145 Discussion Basaloid squamous cell carcinoma of the lung as...

Ngày tải lên: 10/08/2014, 09:23

... Abbreviations NSCLC: non -small cell lung carcinoma; LCNEC: large cell neuroendocrine carcinoma; LCC: large cell carcinoma; SCLC: small cell lung carcinoma; CSC: cancer stem cell; LC: liquid chromatography; ... expression of AL1A1 in lung cancer cell lines, especially in AC cell lines Page 11 of 13 compared to LCC and SCLC cell lines [22-24] To our knowledge, however, this is the first report of the statistically ... common characteristics of LCNEC and SCLC The preferential expression of the cancer stem cell markers in LCNEC over SCLC suggests that the mechanism of increasing the extent of malignancy in LCNEC...

Ngày tải lên: 10/08/2014, 09:22

... were performed The histogenesis of MCC is controversial Possible cells of origin include the epidermal Merkel cell, a dermal Merkel cell equivalent, a neural-crest-derived cell of the amine precursor ... very helpful MCC from other forms of cancer, such as sebaceous cyst, small cell lung cancer (SCLC) and lymphoma, small cell melanoma Each of these cancers has a unique profile as defined by special ... Management of Merkel cell carcinoma Expert Rev Anticancer Ther 2001, 1:441-445 14 Meeuwissen JA, Bourne RG, Kearsley JH: The importance of postoperative radiation therapy in the treatment of Merkel cell...

Ngày tải lên: 09/08/2014, 01:24

... Considering these findings in addition to the characteristics of CDC similar to those of urothelial cancer, chemotherapy is the currently favored approach for patients with metastatic CDC In the case ... as one of the most powerful agents against metastatic RCC [8], and showed a partial response to this drug Recently, the favorable clinical activity of sunitinib against non-clear cell carcinomas, ... treated with sunitinib rather than systemic chemotherapy, considering her poor performance status After courses of sunitinib therapy with 37,5 mg daily schedule, metastases to the lungs and left rib...

Ngày tải lên: 09/08/2014, 02:20

... Extrapelvic spread of squamous cell carcinoma (SCC) of the cervix to the small bowel is rare with only reported cases in the English literature since 1981(PubMed, Medline) We report the case of a 49-year-old ... comprehensive review of the published cases of small bowel metastases from squamous cell carcinoma (SCC) of the cervix in the English literature since 1981 including details of : i) reference #, ... sites of such occurrences are the liver, lungs, and bone marrow The gastrointestinal tract is involved in approximately 8% of patients with carcinoma of the cervix; these being commonly found in the...

Ngày tải lên: 09/08/2014, 02:21

... from the pluripotential surface epithelium of the ovary and from cells with urothelial potential, rather than from a benign or proliferative Brenner tumor precursor The metastatic pathways of the ... urothelial carcinoma of the bladder and ovarian transitional cell carcinoma Arch Pathol Lab Med 2005, 129:194-9 Shen K, Lang J, Guo L: Overexpression of p53 in transitional cell carcinoma of the ... Molecular profile of advanced stage transitional cell carcinoma of the ovary Am J Obstet Gynecol 1997, 177:120-5 Shen K, Lang J, Guo L: Overexpression of C-erbB3 in transitional cell carcinoma of the...

Ngày tải lên: 09/08/2014, 03:22

... consent of the patient or her next of kin for publication could not be obtained A copy of the waiver of consent from the Research Ethics Office, University of Saskatchewan, has been submitted to the ... and an open wedge left lung biopsy Pathological examination of the left lung biopsy confirmed the presence of neoplastic sheets of cells classically distributed along the septal vessels, perivascular, ... distant, extrapelvic sites such as the lungs, para-aortic lymph nodes, and bones occur in the advanced stages of the cancer [2,7] Metastases to the lung comprise up to 3% of cervical cancer treatment...

Ngày tải lên: 09/08/2014, 03:23

... the size of the tumor The slightly hyperintense area in the head of the pancreas had diameters of barely 2.4 × 1.1 cm, with a small (1.0 cm) residual precaval lymph node (Figure 4) There had ... curative resection of an ACC Comparison of the histology of the biopsy and the surgical specimen showed large differences, because after chemotherapy there were necrotic areas, and the vital tumor ... chemotherapy was given to the patient Altogether, the patient was treated with cycles of 5-FU monotherapy (220 mg/m2/d); treatment occurred over eight weeks with a break of two weeks per cycle There...

Ngày tải lên: 09/08/2014, 04:21

... and the negativity for TTF-1 are important in the differential diagnosis from small cell neuroendocrine lung carcinoma [25-27] The monotonous nature of the dermal round cell infiltrate and the ... [6-8] Therapeutic options depend on the stage of the disease at the time of presentation whereas the most important prognostic factor is the absence of nodal involvement [34] Surgery remains the ... Trascription Factor – and cytokeratin 20 aids the distinction of small cell carcinoma from Merkel cell carcinoma, but not pulmonary from extrapulmonary small cell carcinomas Arch Pathol Lab Med 2001,...

Ngày tải lên: 09/08/2014, 07:21

... kidney Clear -cell carcinoma of the breast, resembling clear -cell carClear -cell carcinoma of the breast, resembling clear -cell carcinoma of the kidney The lobular arrangement and the fine vascular ... Mackenzie DH: Clear -cell carcinoma of the lung J Pathol Bact 1964, 87:25-27 Seo I, Tomich CE, Hull MT, Warfel KA: Clear cell carcinoma of the larynx: a variant of mucoepidermoid carcinoma Ann Otol ... Conclusion Clear cell neoplasms arise throughout the body The vacuolated cytoplasm in many of these tumors can be attributed to large quantities of glycogen, as in clear cell carcinomas of the vagina,...

Ngày tải lên: 09/08/2014, 07:21

... Squamous Cell Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their outcome Aust N Z J Surg 1992, 62:697-701 Ames FC, Hickey RC: Squamous cell carcinoma of the skin of the ... number of lymph node metastasis was the presence of previous lesions on the skin of 22 patients with lymph node metastasis over the time pre- The 24 cases of amputations (42.1%) also reflected the ... factor for development of lymph node metastasis, the presence of scar or ulcers previously in the area of the tumor This was observed also in other studies [10,18] The association of UV damage and...

Ngày tải lên: 09/08/2014, 07:21

... glassy cell display large the cervix: the undifferentiated, Glassycells carcinoma of nuclei with prominent nucleoli and Glassy cell carcinoma of the cervix: the undifferentiated, glassy cells ... with the patient, who nevertheless decided to undergo only strict follow-up procedures The patient was then followed with gyneco- Here, we report the case of a stage IB1 cervical glassy cell carcinoma ... study and collected the clinical data MP participated in the design of the study and collected the clinical data AC carried out the histopathological evaluation GS conceived of the study, and participated...

Ngày tải lên: 09/08/2014, 07:21

... patches of squamous cells can be found in adenocarcinoma of the breast and from metastasis of squamous cell carcinoma of an origin somewhere else The etiology and pathogenesis of squamous cell carcinoma ... squamous cell carcinoma when the malignant cells are all of the squamous cell type, there is no relation with the skin and if there is no indication for a primary location somewhere else in the body ... aspiration (FNA) of the swelling was taken The pathology report confirmed the presence of a malignancy The pathologist described atypical epithelial cells with polymorphism of the nucleoli, and the conclusion...

Ngày tải lên: 09/08/2014, 07:22

... Reviewed charts, gathered data, and drafted the manuscript M.G.H.: Aided in the design of the study, helped draft the manuscript D.W.L.: Aided in the design of the study, helped draft the manuscript ... the growing body of data supporting the use of IMRT with SIB for anal cancer Regional control was excellent, despite the common use of low doses per fraction Limitations of our data include the ... after the diagnosis of anal cancer; the patient was disease free at the time of death The second patient died of sepsis associated with metastatic anal cancer 10 months after diagnosis The third...

Ngày tải lên: 09/08/2014, 09:21

... radiative therapy of carcinoma of the prostate A report on 15 years of experience Radiology 1973, 106:407-418 Kastendieck H, Altenahr E: The squamous cell carcinoma of the prostate as an example of ... cell carcinoma of the prostate: presentation of a case and review of the literature Actas Urol Esp 1997, 21:931-935 Ulloa SA, Iturregui JR, Amezquita M, Ortiz VN: Squamous cell carcinoma of the ... variants of adenocarcinoma and other carcinomas of prostate: pathologic criteria and clinical significance Mod Pathol 1997, 10:612-619 Mott LJ: Squamous cell carcinoma of the prostate Report of cases...

Ngày tải lên: 09/08/2014, 10:21

... KS, SH, KI did the assistant of the operation NM diagnosed h the pathology of this case TS was the professor of the surgical science and had a guide All authors read and approved the final manuscript ... included among carcinomas of salivary-gland types along with adenoid cystic carcinoma according to the WHO histological classification of lung cancer MEC is characterized by a mixture of mucusproducing, ... of the tumor Figure Chest radiography revealed a mass shadow in the left lower lung field tumor had a keratin profile of CK7 (+), CK20 (-), and CK5/6 (+), and was determined to be a primary lung...

Ngày tải lên: 10/08/2014, 09:22

... M: Myoepithelioma of the lung: report of two cases and review of the literature Lung Cancer 1998, 20:47-56 18 Masuya D, Haba R, Huang CL, Yokomise H: Myoepithelial carcinoma of the lung Eur J ... Epithelialmyoepithelial carcinoma of the lung A case report and review of the literature Arch Pathol Lab Med 2003, 127:e177-180 Cagirici U, Sayiner A, Inci I, Veral A: Myoepithelioma of the lung ... Epithelial-myoepithelial carcinomas of the bronchus Am J Surg Pathol 2001, 25:1508-1514 Cho KJ, el-Naggar AK, Ordonez NG, Luna MA, Austin J, Batsakis JG: Epithelial-myoepithelial carcinoma of...

Ngày tải lên: 10/08/2014, 09:23

... on the dorsum of the nose: the lesion bled spontaneously at the examination and biopsy confirmed the diagnosis of basal cell carcinoma of the skin Our patient refused the surgical excision of the ... metastases to the nose dorsum [5] In the case that we present, the histological type of the skin lesion as a basal cell carcinoma and the long survival after the local control of both tumors ... two principal points of discussion; the first one concerns the relationship between the skin and cervical tumors, and the second one concerns the origin of the neuroendocrine metastatic disease...

Ngày tải lên: 10/08/2014, 23:20

... drinkers Sequence analysis of exon 10 of the CHK2 gene was performed for all patients However, none of the patients showed the presence of the 1100delC variant Discussion None of the investigated 91 ... patients, they did not detect any truncating mutation Therefore, we were able to confirm these results Nevertheless, they found the missense I157T mutation in 4.1% of the cases In this study, the incidence ... compliance with the Helsinki Declaration This study was reviewed and approved by the ethics committee of the University of Düsseldorf Sequencing of the CHK2 exon 10 including the 1100delC variant...

Ngày tải lên: 11/08/2014, 07:21