mechanism of aging dependent growth arrest by the membrane barrier
Báo cáo khóa học: Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using fluorescence spectroscopy pptx
Ngày tải lên :
07/03/2014, 15:20
... Recently, the resolution of the 3D structure of the AC exotoxin of B anthracis and of its complex with CaM led to the proposal of a different CaM -dependent regulatory mechanism, in which two large ... a direct exploitation of the structural results of the former to explain the mechanism of CaM activation of the latter Crystallization and resolution of the 3D structures of AC and AC–CaM, which ... Brownian rotation of the fluorescent nucleotide Fig Binding of Ant-dATP to AC (d) and AC–CaM (m) The degree of binding of the ligand was calculated from the value of the amplitude of the long lifetime,...
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Báo cáo lâm nghiệp: "Seasonal changes of plant hydraulics, water relations and growth of Aesculus hippocastanum seedlings infested by the leafminer Cameraria ohridella" ppt
Ngày tải lên :
08/08/2014, 00:21
... hydraulic properties of the roots, as indicated by the relative constancy of root hydraulic resistance (Rroot) A detailed analysis of seasonal changes of the hydraulic resistance of different shoot ... absence of borderline effects of mines on the photosynthetic apparatus of still green parts of the leaf blade We note, however, that due to this effect, the impact 104 F Raimondo et al of the ... Cameraria ohridella: a tale of two cities, Entomol Exp Appl 107 (2003) 25–37 [6] Jackson R.V., Bach C.E., Effects of herbivory on growth and survival of seedlings of a rainforest tree, Alphitonia...
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Báo cáo y học: " Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest" pptx
Ngày tải lên :
14/08/2014, 08:21
... suppressing IC261-induced growth arrest 16 17 Results inhibitory activity Click here data file hits cal analysis, andIC261-induced shRNAs used Growth of for file shRNAs of all growth arrest in this study, ... time of each cell line is shown in parentheses (c) Inhibition of HT1080 cell growth by independent shRNA clones that bind to different regions of CSNK1E mRNA (d) The knockdown efficiency of each ... three isoforms of PERIOD proteins and two isoforms of CRYPTOCHROME proteins, which are encoded by PER1, PER2, PER3, CRY1 and CRY2 genes, respectively In order to define the role of each isoform...
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Tài liệu Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway doc
Ngày tải lên :
16/02/2014, 09:20
... inhibition of Bcl-xL ⁄ Bcl-2 functions independently of PPARgamma Cancer Res 65, 1561–1569 41 Jin S, Zhai B, Qiu Z, Wu J, Lane MD & Liao K (2000) c-Crk, a substrate of the insulin-like growth factor-1 ... plots of PI staining are shown in Fig S1 GW9662 is an antagonist of PPARc, and irreversibly inhibits PPARc activity [28] During induction of 3T3-L1 adipocyte differentiation, the presence of GW9662 ... analysis of GW9662 inhibition of adipocyte apoptosis AO ⁄ EB, apoptosis measured by AO ⁄ EB staining; Hoe ⁄ B.F, apoptosis measured by Hoechst 33258 staining Results are means ± SDs of three independent...
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Tài liệu Báo cáo khoa học: Modulation of the enzymatic efficiency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx
Ngày tải lên :
18/02/2014, 17:20
... due to NADPH oxidation after the addition of 370 nm of enzyme The higher concentration of enzyme was necessary because of the low NADPH oxidase activity of FNR All kinetic experiments were performed ... geometry of the tyrosine stacked on the si-face of the flavin in FNRs [12] The single point energies of the flavin–tyrosine system in different conformations were calculated The arrangement of lumiflavin ... interaction of the NADP+ nicotinamide with the flavin is considerably disturbed, probably as a result of changes introduced by the mutations in the environment of the prosthetic group As a result of the...
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Tài liệu Báo cáo khoa học: Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles pptx
Ngày tải lên :
19/02/2014, 05:20
... molecular mechanism of action of those two classes of substituted benzoheterocycles, the kinetic parameters of inhibition were measured Compounds 1c and 2b were chosen as being representative of each ... inhibitors, a molecular model of the methyltetrahydrofolate-binding domain of the rat liver MetS was constructed In the absence of a high-resolution structure of the methyltetrahydrofolate-binding site ... Figure shows the superimposed structures of DHPS and 5-methyltetrahydrofolate The model of the methyltetrahydrofolate-binding site of MetS with one molecule of the substrate included was further...
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USE OF HEALTH AND NURSING CARE BY THE ELDERLY pptx
Ngày tải lên :
05/03/2014, 18:20
... Survey Use of health care The aim of this section is to analyse the current use of health care services by the elderly and the determinants of this utilisation Indicators for the use of health ... hospital, the length of hospital stay of inpatients, the frequency of contacts with a doctor (general practitioner or medical specialist) and consultations of a dentist The partition of inpatient care ... number of admissions is different from the number of discharges (Table 9) The number of admissions during one year is usually higher than the number of discharges (with the exception of Denmark)...
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American Negro Slavery A Survey of the Supply, Employment and Control of Negro Labor as Determined by the Plantation Regime docx
Ngày tải lên :
08/03/2014, 00:20
... for each leg of the voyage, and for leakage of ten per cent of the rum and five per cent of the molasses, and after charging off the whole cost of the ship's outfit and one-third of her original ... the Countess of Lincoln, in Alex Young, Chronicles of the First Planters of Massachusetts Boy (Boston, 1846), p 312.] [Footnote 3: _Records of the Court of Assistants of the Colony of Massachusetts ... south side of the island where an abundance of savannahs facilitated tillage; but the development of sugar culture proved slow by reason of the paucity of slaves and the unfamiliarity of the settlers...
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Báo cáo Y học: Mechanism of 1,4-dehydrogenation catalyzed by a fatty acid (1,4)-desaturase of Calendula officinalis pptx
Ngày tải lên :
08/03/2014, 09:20
... tosylate of 2-octyn-1-ol to give [8,82H2]-1 after semihydrogenation and methyl esterification of the intermediate diyne In a similar manner, dec-9-ynoic acid was C-alkylated with the tosylate of [1,1-2H2]-2-octyn-1-ol ... with a plasmid (pYJ) comprised of the pYES2 vector Fig Generic mechanistic scheme showing the stepwise removal of hydrogens in fatty acid (1,2)-desaturation Structure of the putative diiron oxidizing ... (100 mgÆL)1) was administered to cultures (50 mL) of the pYJ/DTY10a2 strain of S cerevisiae incubated at 20 °C for days to permit relatively rapid growth and then at 15 °C for a further days to...
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Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc
Ngày tải lên :
08/03/2014, 09:20
... SecB dependency of the targeting of mutant prePhoE By the substitution of an a-helix-promoting residue (Leu, Ala or Cys) for the helix-breaking Gly)10 of the signal sequence of PhoE, the a-helix ... overloading of the SRP pathway The re-routing of (G-10L)prePhoE to the Sec translocon via the SRP instead of the SecB pathway could be explained by the increased hydrophobicity of the hydrophobic core of ... accumulation of truncated forms of outer -membrane PhoE protein of Escherichia coli K-12 J Mol Biol 189, 449–455 31 Bosch, D., de Boer, P., Bitter, W & Tommassen, J (1989) The role of the positively...
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Synthesis and photoluminescence property of silicon carbon nanowires synthesized by the thermal evaporation method
Ngày tải lên :
16/03/2014, 15:21
... nanowires (Fig 5b) The presence of peaks demonstrates that the nanowires are composed of Si, C and small amount of O It is found that the molecular ratio of Si/C/O of the nanowires is about 3:2:2, ... is supported by the Creative Research Group of National Science Foundation of China (Grant no 50721003), the Foundation of the Ministry of Education of China for Returned Scholars (Grant no 2005383) ... With regard to energetic consideration, the formation of stacking faults during the growth of SiC nanowires is favorable due to the contribution of stacking faults themselves with lower energy By...
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Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx
Ngày tải lên :
24/03/2014, 00:21
... incomplete picture of the ligand binding domain of AhR and of its interactions with PCDDs It should also be emphasized that the LBD is part of a much larger protein and some features of the Ah receptor ... helix, which shows a Ê translational displacement of A that allows the accommodation of the heme cofactor (Fig 1C) [12] The hydrophobic core of the three domains is generally well conserved, ... transducing regions of PYP and FixL are thus located at the opposite ends of the Fig Schematic representation of the HERG (A), PYP (B), and FixL (C) PAS domains displaying the high degree of structural...
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The Management of Community-Acquired Pneumonia in Infants and Children Older Than 3 Months of Age: Clinical Practice Guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America pot
Ngày tải lên :
28/03/2014, 09:20
... Strength of Recommendations and Quality of Evidence Strength of recommendation Clarity of balance between and quality of evidence desirable and undesirable effects Methodologic quality of supporting ... time of initial evaluation The presence of significant comorbid conditions is also a risk factor for the development of pneumonia; the presence of pneumonia often results in a worsening of the ... Diseases Society of America (IDSA) guidelines, which included a systematic weighting of the quality of the evidence and the grade of the recommendation [3] (Table 1) A detailed description of the methods,...
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Báo cáo khoa học: The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p ppt
Ngày tải lên :
30/03/2014, 04:20
... Fig 1, deletion of OXA1 decreased the rate of formation of all aminoglycerophospholipids The rate of PtdSer synthesis decreased to 80%, the rate of PtdEtn formation to 70% and that of PtdCho synthesis ... cardiolipin Mean values of at least three independent measurements and standard deviations (SD) are shown Phosphatidylethanolamine of yeast mitochondria Deletion of OXA1 affects the rate of PtdEtn synthesis ... mutants of MBA1, which encodes a component involved in the Oxa1p -dependent export of mitochondrially encoded proteins into the IMM [17], and YME1, which encodes an intermembrane spacelocated ATP-dependent...
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Báo cáo hóa học: " The use of RNA-dependent RNA polymerase for the taxonomic assignment of Picorna-like viruses (order Picornavirales) infecting Apis mellifera L. populations" pptx
Ngày tải lên :
20/06/2014, 01:20
... evolution of these honeybee viruses in the context of the order Picornavirales Methods Validation of RdRp oligonucleotide probes Multiple amino acid and nucleotide sequences of the RNA -dependent ... existing in other parts of the genomes of these viruses have contributed to their pathological characteristics, for example the specificity of KV to brain tissues, and the ability of DWV and VDV to ... AAM47569 AAM47570 AAM47571 4) The end of domain V and the start of domain VI show the greatest region of amino acid variability in these viruses, with each of the viruses having unique amino acid...
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Báo cáo hóa học: " Research Article Space-Varying Iterative Restoration of Diffuse Optical Tomograms Reconstructed by the Photon Average Trajectories Method" ppt
Ngày tải lên :
22/06/2014, 23:20
... boundary of a circular object at equal step angles Our investigations [11–15] show that by choosing the optimal values of the time-gating delay of receivers, the length of the middle segment of the ... solution of the time -dependent diffusion equation for the instantaneous point source with the use of the FEM method The time-gating delays of the receivers were chosen so that the lengths of the ... use of the invariant PSF The crosses in the figure mark the real positions of the centers of inhomogeneities It is obvious that an application of the spatially invariant model leads to a shift of...
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Báo cáo lâm nghiệp: "Discrimination of coated carbide tools wear by the features extracted from parallel force and noise level" potx
Ngày tải lên :
08/08/2014, 01:22
... forces of dynamometer that was held on the table of the NC machine Turning was performed by the corner of the cutting edge along the edge of the disk (work material) with depth of cut of mm The ... feasibility of techniques of pattern recognition using the cutting sound for the discrimination of the various stages of edge wear was clarified [7] Another study revealed that behavior of acoustic ... the corner of the cutting edge in the speed of 0.05 mm/rev When the cutting tools finished one pass of cutting (cutting from bottom face to top face of the disk with cutting length of about 500...
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báo cáo khoa học: " Insight into the early steps of root hair formation revealed by the procuste1 cellulose synthase mutant of Arabidopsis thaliana" doc
Ngày tải lên :
12/08/2014, 05:20
... bulging phenotype of prc1-1 is at least partially independent of ethylene whereas the restoration of hair formation in rhd6-1 by prc1-1 is ethylene dependent (Fig 7K, L) Is restoration of root hairs ... whole of the outer face of some prc1-1 trichoblasts Nevertheless, constitutive expression of the activated GTP-bound form of Rop2 and Rop4 results in bulging of epidermal cells reminiscent of the ... initiation of root hairs [12] Cellulose is a major structural component of cell walls comprising chains of β-1,4-linked glucosyl residues which are assembled into microfibrils The arrangement of the...
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The common errors in using some skinds of nouns in english made by the eleventh grade student at nguyen trai hight school, thai binh
Ngày tải lên :
16/07/2015, 08:06
... assistant secretary of state two assistant secretaries of state 14 a woman-doctor three women-doctors a doctor of philosophy two doctors of philosophy maid of honor maids of honor I.3.3.1 Pluralize ... some mistakes in using some kinds of nouns With the aim of helping learners of English to overcome some difficulties in using some kinds of nouns, and with the aim of making the nouns to be more ... word in the subject of a clause, the object of a verb, or the object of a preposition I.2.2 Functions I.2.2.1 Subject of a verb Elephants eat grass Noun plays as a subject of a verb The animal...
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