measurement techniques for red blood cell deformability recent advances

... aOR adjusted for point.bOR adjusted for year cOR adjusted for g/dl CI, confidence interval; ICU, intensive care unit; LOD, Logistic Organ Dysfunction; OR, odds ratio; RBC, red blood cell One of ... ventilation Whether efforts to limit blood transfusion in the ICU just delay administration of RBC to the post-ICU period is unclear In addition, although predictive factors for the need for RBC transfusion ... intensive care unit; LOD, Logistic Organ Dysfunction; RBC, red blood cell; SAPS, Simplified Acute Physiology Score Page of (page number not for citation purposes) We examined the characteristics...

Ngày tải lên: 13/08/2014, 03:20

... older blood group received RBCs that had been stored for a median of six days, which was significantly longer than patients in the newer blood group, who received blood that had been stored for ... composite morbidity was about 50% higher for patients receiving RBCs stored for 14 days than for patients receiving RBCs stored for one day Page of 12 (page number not for citation purposes) Critical ... the red cell membrane during conventional blood preservation Semin Hematol 1989, 26:307-312 Leal-Noval SR, Jara López I: Do multiple blood transfusions predispose for a higher rate of non -blood- related...

Ngày tải lên: 13/08/2014, 20:21

... BFJ: Decreased red blood cell deformability and impaired oxygen utilization during human sepsis Am Surg 1993, 59:65-68 37 Baskurt OK, Gelmont D, Meiselman HJ: Red blood cell deformability in ... Medical Center with waiver of written informed consent (# 09-953) Red blood cell transfusion characteristics Packed red blood cell units were obtained from the blood bank (St John’s Mercy Medical ... for individual patients from before and after transfusion A Recovery slopes for individual patients from before and after transfusion for full sample B NIRVO2 for individual patients from before...

Ngày tải lên: 20/06/2014, 22:20

... red cell concentrates during storage is prevented by prestorage white cell reduction Transfusion 1997, 37:678-684 Anniss AM, Sparrow RL: Storage duration and white blood cell content of red blood ... McIntyre LA, Fowler RA: Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients CMAJ 2008, 178:49-57 90 Dodd RY: Current risk for transfusion transmitted ... M, Boyce NW: Appropriateness of red blood cell transfusion in Australasian intensive care practice Med J Aust 2002, 177:548-551 Scharte M, Fink MP: Red blood cell physiology in critical illness...

Ngày tải lên: 20/06/2014, 23:20

... Blood Group Antigens 92 ABO Blood Group 92 Rh Blood Group 97 P Blood Group 98 Lutheran Blood Group 99 Kell Blood Group 99 Lewis Blood Group 100 Duffy Blood Group 101 Kidd Blood Group 102 LW Blood ... 38 Red Cell Morphology and Shape Change 38 Red Cell Deformability 40 Membrane Transport and Permeability 41 V VI Contents 3.1 3.2 3.2.1 3.2.2 3.2.2.1 3.2.2.2 Stereotactic Structure of Red Cell ... Red Cell Membrane Proteins 349 Red Cell Membrane Lipids 350 Red Cell Deformability 350 Biophysical characteristics 352 Membrane Transport 355 Ultrastructure of Red Cell Membranes In Situ 358 Protein...

Ngày tải lên: 29/06/2014, 11:20

Ngày tải lên: 07/08/2014, 18:21

... blood transfusions is considered a relevant, important goal in cardiac surgery During cardiac operations under CPB, two concurrent events, namely blood loss and red blood cell dilution due to positive ... Anesthesiologists Special Task Force on Blood Transfusion, Spiess BD, ShoreLesserson L, Stafford-Smith M, Mazer CD, Bennett-Guerrero E, Hill SE, Body S: Perioperative blood transfusion and blood conservation ... drop and need for allogeneic blood Hemodilution has been identified as a major factor influencing the decision to transfuse Likewise, several variables associated with total red cell mass, such...

Ngày tải lên: 10/08/2014, 10:20

... of (page number not for citation purposes) Critical Care Vol 11 No Zilberberg et al Key messages • • • Allogeneic red blood cell transfusion is an independent risk factor for the development ... Germain M, Goldman M, Toye B, Leukoreduction Study Investigators, et al.: Clinical outcomes following institution of the Canadian universal reduction program for red blood transfusions JAMA 2003, ... adjusting for time at risk for the outcome event was further conducted to determine independent risk factors for ARDS Adjusted odds ratios (ORs) of developing ARDS were calculated for the presence...

Ngày tải lên: 13/08/2014, 03:21

... storage on red blood cell rheological properties J Surg Res 2002, 102:6-12 Tsai AG, Cabrales P, Intaglietta M: Microvascular perfusion upon exchange transfusion with stored red blood cells in norTransfusion ... unreasonable to transfuse red cells in certain patients with critical noncardiac end-organ ischemia whose Hb levels are as high as 10 g/dl" [111] Funding was recently secured in the UK for a multi-center ... = red blood cell; RCT = randomized controlled trial; WFNS = World Federation of Neurological Surgeons score Page 14 of 22 (page number not for citation purposes) Available online http://ccforum.com/content/13/3/R89...

Ngày tải lên: 13/08/2014, 16:21

... Research, Hartford Hospital 21 Page 10 of 11 (page number not for citation purposes) AAAB: Facts about blood and blood banking [http:// www.aabb.org/Content/About _Blood/ Facts_About _Blood_ and _Blood_ Banking ... Stored packed red blood cells contain a procoagulant phospholipid reducible by leukodepletion filters and washing Transfus Apher Sci 2008, 38(2):141-147 Sweeney J, Kouttab N, Kurtis J: Stored red ... triphosphate in red blood cells during storage Transfusion 2008, 48(6):1081-1089 Tsai AG, Cabrales P, Intaglietta M: Microvascular perfusion upon exchange transfusion with stored red blood cells in...

Ngày tải lên: 13/08/2014, 19:20

... 14 15 16 17 18 19 20 21 22 Tinmouth AT, McIntyre LA, Fowler RA: Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients CMAJ 2008, 178:49-57 ... Cite this article as: Mukhopadhyay et al., The use of a blood conservation device to reduce red blood cell transfusion requirements: a before and after study Critical Care 2010, 14:R7 ... PRBC: packed red blood cell; RRT: renal replacement therapy; TACO: transfusion-associated circulatory overload; TRALI: transfusion-related acute lung injury; VAMP: Venous Arterial blood Management...

Ngày tải lên: 13/08/2014, 20:21

... E -Cell 2: Multi-platform E -Cell simulation system Bioinformatics 2003, 19:1727-1729 Takahashi K, Kaizu K, Hu B, Tomita M: A multi-algorithm, multitimescale method for cell simulation Bioinformatics ... application to metabolism in human red blood cells J Theor Biol 1996, 179:329-368 Ni TC, Savageau MA: Application of biochemical systems theory to metabolism in human red blood cells Signal propagation ... dynamics in the human red cell Part III – Metabolic reaction rates J Theor Biol 1990, 142:41-68 Joshi A, Palsson BØ: Metabolic dynamics in the human red cell Part IV – Data prediction and some model...

Ngày tải lên: 13/08/2014, 22:22

... DA: Anemia and red blood cell transfusion in neurocritical care Crit Care 2009, 13:R89 Smith MJ, Stiefel MF, Magge S, Frangos S, Bloom S, Gracias V, Le Roux PD: Packed red blood cell transfusion ... therapeutic rationale for the avoidance of anemia in patients with brain injury [4] Physiological studies have demonstrated improvements in cerebral oxygenation when red blood cell (RBC) transfusions ... MN: Red blood cell transfusion increases cerebral oxygen delivery in anemic patients with subarachnoid hemorrhage Stroke 2009, 40:3039-3044 Kramer et al Critical Care 2011, 15:R30 http://ccforum.com/content/15/1/R30...

Ngày tải lên: 14/08/2014, 07:21

Ngày tải lên: 13/11/2014, 10:36

... between the extents of red blood cell aggregation for human red blood cells suspended in 70 kDa dextran and in autologous plasma 15 Figure 1.6: Aggregates formation in blood of healthy human ... In microcirculatory blood flow, whether or not red blood cell aggregates can form in the flow stream also depends on the magnitude of shear forces acting on the red blood cells in their flow ... heterogeneity of red blood cells distribution in the network by triggering the effects of red blood cell screening (103) and plasma skimming (53, 122) shown in Fig 1.10 CELL SCREENING Cell- cell interactions...

Ngày tải lên: 10/09/2015, 15:52

... Hematocrit (Hct) is the ratio of the volume of red blood cells (RBCs) to the total blood volume Hct is well known to be a major rheological determinant of blood viscosity and flow resistance [32-34] ... simulates the polycythemia disease 2.3 Cell- free layer 2.3.1 Cell- free layer formation One of the major hemodynamic features in microcirculation is the cell- free layer formation between RBC core and ... leads to a decrease in blood viscosity Secondly, the presence of cellfree layer in microvessels or microtubes contributes to a lower blood viscosity than blood samples with uniform radial distributions...

Ngày tải lên: 05/10/2015, 18:59

... technique) More recently, a multicentre study compared multiple techniques with oesophageal Doppler [10] Patients from three different intensive care units underwent paired cardiac output measurements ... regarding the velocity profile is that all red blood cells are moving at approximately the same speed The cross-sectional area of the descending aorta can be measured at the bedside by using transoesophageal ... It is therefore mandatory to recheck the signal quality, on a systematic basis, before acquiring and interpreting Doppler-derived data Failure to reposition the probe before each measurement...

Ngày tải lên: 12/08/2014, 18:21

... resolution and accuracy of quantitative EBIC for the extraction of SRV for solar cells vii viii Advanced Electron-Beam Based Techniques for Solar Cell Characterization List of Figures Figure ... 100 pF xi xii Advanced Electron-Beam Based Techniques for Solar Cell Characterization The values assigned for each parameter are typical for solar cells with a sample size of about cm2 ... solar cell This suggests that the performance of solar cells could be further improved - times if different concepts are used to produce a “third generation” of high-performance cells [15, 16] For...

Ngày tải lên: 09/09/2015, 11:08

... Phosphatidylserine exposure of stored red blood cells 103 4.5.7 Membrane redox activity of young and old red blood cells 105 4.5.8 Surface structure of young and old red blood cells 105 Discussion ... of young and old red blood cells 100 4.5.4 Determination of Ca2+ content in young and old red blood cells 100 4.5.5 Phosphatidylserine exposure of young and old red blood cells 101 4.5.6 ... Ca2+ content in sickle red blood cells 57 4.1.5 Investigation of Ca2+ uptake in sheep red blood cells 60 4.2 Investigation of phosphatidylserine exposure in red blood cells 63 4.2.1 Phosphatidylserine...

Ngày tải lên: 15/11/2015, 12:54