... hemorrhage J Cereb Blood Flow Metab 2001, 21:804-810 92 Reeves BC, Murphy GJ: Increased mortality, morbidity, and cost associated with red blood cell transfusion. .. of cell- free hemoglobin, ... about 0.5 g/dl per day [9-12]. The etiology of ICU-acquired anemia is multifactorial. Systemic inflammation reduces red CBF: cerebral blood flow; C a O 2 : arterial oxygen content; CMRO 2 : cerebral ... justified. Emerging data indicates that stored blood has important differences from patients' own blood. A number of changes occur over time as RBCs are being stored; some of these alterations could
Ngày tải lên: 13/08/2014, 16:21
... transfusions is con- sidered a relevant, important goal in cardiac surgery. During cardiac operations under CPB, two concurrent events, namely blood loss and red blood cell dilution due to pos ... (≤6 units) blood product exposure and reduced long-term survival [3]. As the risk of transfusion-asso- ciated adverse outcomes may depend on the amount of transfusion [4], reduction of blood transfusions ... RESEARC H ARTIC LE Open Access Intra-operative intravenous fluid restriction reduces perioperative red blood cell transfusion in elective cardiac surgery, especially in transfusion-prone patients:
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries" potx
... Facts about blood and blood banking [http:// www.aabb.org/Content/About _Blood/ Facts_About _Blood_ and _Blood_ Banking ] Ho J, Sibbald WJ, Chin-Yee IH: Effects of storage on efficacy of red cell transfusion: ... Stored packed red blood cells contain a procoagulant phospholipid reducible by leukodepletion filters and washing Transfus Apher Sci 2008, 38(2):141-147 Sweeney J, Kouttab N, Kurtis J: Stored red ... triphosphate in red blood cells during storage Transfusion 2008, 48(6):1081-1089 Tsai AG, Cabrales P, Intaglietta M: Microvascular perfusion upon exchange transfusion with stored red blood cells in
Ngày tải lên: 13/08/2014, 19:20
Báo cáo y học: "Duration of red blood cell storage and outcomes in pediatric cardiac surgery: an association found for pump prime blood" doc
... storage of the red blood cells they received. The newer blood group included patients who received only red blood cells stored for less than or equal to four days and the older blood group included ... intraoperative red blood cell transfusions to prime the circuit and oxygenator and to replace blood lost during surgery. The purpose of this study was to investigate the influence of red blood cell storage ... newer blood and 17.1% of the patients receiving older blood (P = 0.027). After adjusting for other possible confounding variables, red blood cell storage time remained an independent predictor
Ngày tải lên: 13/08/2014, 20:21
Báo cáo y học: "Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition" docx
... Abstract Background: Cell simulation, which aims to predict the complex and dynamic behavior of living cells, is becoming a valuable tool. In silico models of human red blood cell (RBC) metabolism ... metabolism in human red blood cells. J Theor Biol 1996, 179:329-368. 13. Ni TC, Savageau MA: Application of biochemical systems the- ory to metabolism in human red blood cells. Signal propaga- ... dynamics in the human red cell. Part III – Metabolic reaction rates. J Theor Biol 1990, 142:41-68. 11. Joshi A, Palsson BØ: Metabolic dynamics in the human red cell. Part IV – Data prediction and some
Ngày tải lên: 13/08/2014, 22:22
Báo cáo y học: "Red blood cell transfusion in patients with subarachnoid hemorrhage: a multidisciplinary North American survey" doc
... Anemia and red blood cell transfusion in neurocritical care. Crit Care 2009, 13:R89. 5. Smith MJ, Stiefel MF, Magge S, Frangos S, Bloom S, Gracias V, Le Roux PD: Packed red blood cell transfusion ... cerebral oxygena- tion when red blood cell (RBC) transfusions are us ed to raise Hb levels in anemic SAH patients, particularly when oxygen delivery and cerebral perfusion are reduced [4-7]. Several ... RESEARCH Open Access Red blood cell transfusion in patients with subarachnoid hemorrhage: a multidisciplinary North American
Ngày tải lên: 14/08/2014, 07:21
Effect of red blood cell aggregation on arteriolar cell free layer formation and its physiological functions
... EFFECT OF RED BLOOD CELL AGGREGATION ON ARTERIOLAR CELL- FREE LAYER FORMATION AND ITS PHYSIOLOGICAL FUNCTIONS ONG PENG KAI NATIONAL UNIVERSITY OF SINGAPORE 2011 EFFECT OF RED BLOOD CELL AGGREGATION ... rheological factors such as red blood cell aggregation and flow rate 1.3 Cell- free layer formation in microvessels It has been long established that red blood cells flowing in a narrow ... migration of the cells to the center of the tube in a process known as red blood cell axial migration (40, 58, 103, 140) Axial migration of the red blood cell is induced by...
Ngày tải lên: 10/09/2015, 15:52
Effects of red blood cell aggregation, hematocrit and tube diameter on wall shear stress in microtubes
... EFFECTS OF RED BLOOD CELL AGGREGATION, HEMATOCRIT AND TUBE DIAMETER ON WALL SHEAR STRESS IN MICROTUBES YANG SHIHONG NATIONAL UNIVERSITY OF SINGAPORE 2010 EFFECTS OF RED BLOOD CELL AGGREGATION, ... (September 2007- present) • Conducted research on blood rheology in microcirculation, including red blood cell aggregation, hematocrit, plasma viscosity and blood viscosity and tube diameter • Supervised ... of ID 50 µm in non-aggregating blood suspended in PBS, normal aggregating blood and disease aggregating blood 27 Figure Comparison of relative WSS of blood samples at 40% Hct in microtube
Ngày tải lên: 05/10/2015, 18:59
Novel Insights in the Regulation of Phosphatidylserine Exposure in Human Red Blood Cell
... Exposure in Red Cells 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 Kucherenko YV, Bernhardt I: Natural antioxidants improve red blood cell “survival” in non-leukoreduced blood samples Cell Physiol ... kinase Cα and P-type Ca2+ channel Cav2.1 in red blood cell calcium signalling Cell Physiol Biochem 2013;32:883-891 Kaestner L: Channelizing the red blood cell: molecular biology competes with patch-clamp ... human red blood cells depending on cell age Cell Physiol Biochem 2016;38:1376-1390 Wesseling MC, Wagner-Britz L, Boukhdoud F, Asanidze S, Nguyen DB, Kaestner L, Bernhardt I: Measurements of intracellular
Ngày tải lên: 16/12/2017, 16:43
Red blood cell distribution width and platelet counts are independent prognostic factors and improve the predictive ability of IPI score in diffuse large B-cell lymphoma patients
... myeloid lines such as myeloid derived suppressor cells (MDSCs), macrophages and dendritic cells (DCs), as well as the reduction of mature red blood cells and platelets [44] But the exact function ... pPCL: Primary plasma cell leukemia; RCHOP: Rituximab versus cyclophosphamide, doxorubicin, vincristine and prednisolone; RDW: Red blood distribution width; WBC: White blood cell count Acknowledgements ... 10.1080/2162402 Open Access Red blood cell distribution width and platelet counts are independent prognostic factors and improve the predictive ability of IPI score in diffuse large B -cell lymphoma patients
Ngày tải lên: 17/06/2020, 19:07
Packed red blood cell transfusion associates with acute kidney injury after transcatheter aortic valve replacement
... aortic valve replacement Packed red blood cell transfusion has been associated with morbidity and mortality after cardiac surgery We hypothesized that packed red blood cell transfusion independently ... Reynolds H, Azarov I, et al Nitric oxide scavenging by red blood cell microparticles and cell- free hemoglobin as a mechanism for the red cell storage lesion Circulation 2011;124(4):465–76 37 Haase ... packed red blood cell, ICU intensive care unit Merchant et al BMC Anesthesiology (2019) 19:99 Page of 10 Fig Number of patients with post TAVR acute kidney injury (AKI) stratified by packed red blood
Ngày tải lên: 13/01/2022, 01:52
gender disparities in red blood cell transfusion in elective surgery a post hoc multicentre cohort study
... differences between men and women being eliminated ▪ Perioperative blood loss, including the so-called hidden blood loss, and red blood cell volume transfused were precisely calculated ▪ Owing to the ... differences in the transfusion-related modifiable risk factors such as anaemia, blood loss and transfusion of red blood cells (triad of adverse outcome) ▪ Comparing absolute transfusion-related data ... own blood by reducing the above-mentioned transfusion-related risk factors— anaemia, blood loss and red blood cell (RBC) transfusion—with the ultimate goal of improving the patient’s outcome and
Ngày tải lên: 04/12/2022, 10:34
BASAL CELL CARCINOMA pdf
... cell 20 Basal Cell Carcinoma cycle, arresting irregularly growing cells via G1 / G2 transition of the cell cycle... developed to recognize normal squamous epithelium and squamous cell ... basal cell carcinomas (BCC) While it has not been fully clarified which primary cell gives rise to basal cell carcinomas it is supposed that BCCs arise from interfollicular basal cells, ... squamous cell carcinomas in the head-neck-region Fig 3 Immunoreactive scores (IRS, cf 144, 145) of expression of CD44v6, E48 and U36 in basal cell carcinomas (mean values) 26 Basal Cell
Ngày tải lên: 27/06/2014, 10:20
Báo cáo y học: "Daily rhythm of cerebral blood flow velocity" pdf
... consequence of the fall in the overall reduced metabolic level [8,10,11] and reduced cognitive processing [12]. Additionally, the reduced physical activity [13], reduced body temperature, and the ... the investigator (DAC) monitored the quality of the recordings. The recordings were scored by RQS and DAC. Blood pressure, heart rate, and end-tidal CO2 An automated blood pressure cuff was placed ... ultrasonography is predicated on a theory that involves the measurement of moving objects when combined with radar. When the instrument emits the sound wave, it is reflected by the blood cells that are
Ngày tải lên: 10/08/2014, 09:20
báo cáo khoa học: " Inorganic phosphate nanorods are a novel fluorescent label in cell biology" pdf
... control apoptosis has been induced in cells using camptothecin (~2.5 mM) for 4 h of incubation (Fig. 9(A-A2)). The red- colored (TMR red- stained nuclei) apoptotic cells (Fig. 9A) were visualized under ... delivery Cell culture experiments HUVEC and 786-O cells were cultured at 105 cells/2 ml in six well plates for ~24 h at 37°C and 5% CO2 in EBM and DMEM complete media For investigating the cellular ... of apoptosis of cells using annexin-FTIC-PI, Bio Vision, USA, catalog # K101-100) Cell viability for another set of cells was determined through staining with trypan blue and cells were counted
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: "Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: refinement of the requirements for SARS coronavirus cell entry" pdf
... domain to mediate cell cell fusion or pore formation Capacity of S proteins with mutations in the aromatic domain to mediate cell cell fusion or pore formation Cell cell fusion of 293T cells expressing ... shown by exchange of intracellular dyes, unable to transfer spontaneously from one cell to another Full cell cell Full cell cell fusion, as shown by exchange of intracellular dyes, unable to transfer ... one cell to another Double staining of a cell indicated full cell cell fusion Pore formation does not result in dye exchange L cells expressing ACE2 were stained green by CMFDA and 293T cells
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: "Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes" pdf
... highly in AF cells and NP cells when compared with AC cells, when assessed using qRT-PCR In contrast, the microarray data showed AQP1 at lower levels in AF cells compared with the other two cell types, ... cells (P < 0.0001) In addition, T was expressed in all three human cell types (Figure 5a) with expression significantly higher in NP cells when compared with both AC cells (P = 0.02) and AF cells ... annulus fibrosus (AF) cells and NP and articular cartilage (AC) cells (P < 0.05) † statistical significance between AF cells and AC cells (P < 0.05) compared with normal NP cells (P = 0.0002, P
Ngày tải lên: 12/08/2014, 11:23
Báo cáo y học: "Nuclear import of Avian Sarcoma Virus integrase is facilitated by host cell factors" pdf
... fusion proteins shared any of the cytosolic components that are required for import of GST-TAg or GST-U1A. For these studies, a competitor thioredoxin fusion protein was prepared that included ... digitonin-permea-bilized HeLa cellsFigure 3 Nuclear import of GST-NLS substrates in digitonin- permeabilized HeLa cells. GST-NLS fusion proteins were incubated in digitonin permeabilized HeLa cells for 30 min ... right. The lower value for import of GST-IN (201–236) compared to GST-IN (1–286) reflects the fact that a larger percentage of cells had whole cell staining (in which nuclear import could not be assessed)
Ngày tải lên: 13/08/2014, 05:21
Tài liệu Báo cáo khoa học: Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay docx
... hemagglutination assay [4], where the ability of a given virus to bind to and agglutinate red blood cells (RBCs) is measured. In the case of influenza, for example, the hemagglu- tination assay takes advantage ... 1699–1712 ª 2011 The Authors Journal compilation ª 2011 FEBS Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay Udayanath Aich 1 , ... glycans from different cell types would permit generation of different glycan fractions from these cell types where each fraction would be characterized in terms of the predominance of a specific...
Ngày tải lên: 14/02/2014, 19:20
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