mathematical thinking and learning

... generated and expanded in vitro, might tip the balance and allow a true curative action in animal models of T1D [12], and much work is now directed to this area [20] Two recent studies in T1D and experimental ... withdrawal of anti-TNF-α [19] and thus, despite the dampening of joint inflammation and the reinstatement of fully functional CD4+CD25+ Treg, RA is still not cured These strands of evidence seem to ... series of studies in RA and other chronic autoimmune joint inflammatory diseases such as juvenile idiopathic arthritis and spondyloarthropathies, in which phenotype, distribution and functional studies...

Ngày tải lên: 09/08/2014, 06:23

... well-known risk factor for knee OA, and to a lesser degree for hip OA and hand OA, and probably acts through a change in load distribution in the knee [72], and systemic and local inflammatory cytokines ... specific subgroup of hand OA with worse clinical and structural outcomes The ESCISIT task force [36] postulated that erosive hand OA targets interphalangial joints in the hand and shows radiographic ... component in erosive hand OA However, to date, only a few small pilot studies have specifically targeted erosive hand OA [37] Examples Rozendaal and colleagues [33] defined beforehand a subgroup analysis...

Ngày tải lên: 12/08/2014, 15:22

... Biology and Medical Modelling 2006, 3:34 describe a computer simulation model that follows the formation and destruction of red blood cells (RBC) When standard assumptions about red cell formation and ... and RDW-CV% remain long after the folate level has returned to normal There may be no other method for detecting recent folate deficiency and hence no gold standard to calculate sensitivity and ... detecting deficiencies in iron and folate does not supplant standard measures of serum iron and folate, but rather provides a useful tool in regions where anaemia is prevalent and resources limited Technical...

Ngày tải lên: 13/08/2014, 23:20

... 559 and 1233 patients in the routine clinic database were recorded for severe bacteria pneumonia (81.8% and 96.4%, respectively), herpes zoster (83.3% and 88.8%), oral candidiasis (55.9% and ... (12.2% and 12.2%), Cryptococcus meningitis (+12.5% and 12.5%), and Kaposi’s sarcoma (+16.7% and +150%) Although the same number of patients was identified with Cryptococcus meningitis and Kaposi’s ... analysis BC, PS and TM participated in its design and coordination, and provided comments on the manuscript PJE conceived the study, participated in its design and coordination, and drafted the...

Ngày tải lên: 20/06/2014, 08:20

... the conceptually similar terms machine learning and pattern recognition rank sixth and twelfth among the top rising terms There are social, geographic, and linguistic forces that inuence lexical ... between C and k is twice as great in year y as it is atemporally, the decision rule is passed The generator G k is considered perturbed in year y and k is added to ModifyList(y) In the training and ... phenomena in which words and phrases are coined or take on new meanings (Bauer, 1994; Jeffers and Lehiste, 1979) Below we describe an application in document clustering and point toward a theoretical...

Ngày tải lên: 08/03/2014, 04:22

... between ANES and Leading Text Searchable LEAD document processing software consists of a 500-statement PL1 program and a 23rule sentence and paragraph boundary recognition grammar, and operates ... type (general news, which includes standard news articles, graphics, editorials, LEAD=BODY, letters/Q&A columns, and music and book reviews; lists; newsbriefs; and television program transcripts) ... rating and assigning attributes to the 2,727 test corpus documents and LEADs I would also like to thank Breck Baldwin, Afsar Parhizgar, David Schmeer and Paul Zhang for their comments and suggestions...

Ngày tải lên: 17/03/2014, 07:20

... threshold and expanding treatment coverage may be an urgent next step in China to control both AIDS and non-AIDS related mortality and morbidity Most patients still present with late disease, and fewer ... development, expanding HIV testing and treatment, discovering and developing new ARV drugs, optimizing the ART delivery system, and improving therapy for non-AIDS related conditions and coinfections ... NRTIs (ABC, ddI, d4T, 3TC, TDF, and AZT), NNRTIs (EFV and NVP), and one boosted PI (LVP/r) In addition, three drugs - raltegravir (integrase inhibitor), darunavir (PI), and etravirine (NNRTI) are...

Ngày tải lên: 10/08/2014, 05:21

... http://www.jeccr.com/content/30/1/30 PCR Amplification and sequencing The two codons of KRAS (12 and 13) and two exons of EGFR (19 and 21) were amplified by PCR using the following forward and reverse primers: exon of ... Diagnosis and Therapy Center of Lung Cancer, Tianjin 300060, China Authors’ contributions ZZ, CW and BS designed the study; LS and QZ performed experiments; LS and HL analyzed data and prepared ... discordance in KRAS and EGFR gene status between primary tumors and corresponding metastases was 24% and 28% in 25 patients with NSCLC, respectively [24] Schmid et al reported that the KRAS and EGFR gene...

Ngày tải lên: 10/08/2014, 10:21

... biết, Nxb Hà Nội Tiếng Anh 13 Adam McCarty (2001), Vietnam in ASEAN, Regional Intergration Process and Challenges, Hanoi 14 Damien J Neven (2000), Evaluating the effects of non-tariff barriers, University ... APEC Study Centre-Monash University (2003), European Unilateralism-Environmental Trade Barriers and the Rising Threat to Prosperity through Trade Website 16 http://www.census.gov/foreign-trade/statistics/index.html ... http:/thietbiphantichmoitruong.wordpress.com/2011/04/08/rao-can-moi-truongquan-trac-moi-truong-lien-tuc 43 http://environment-safety.com/courses/EnvManagement/envStandards.htm 44.http://vea.gov.vn/vn/khoahoccongnghe/nhanxanh/gioithieunhansinthai/Pages 45 http://www.census.gov/foreign-trade...

Ngày tải lên: 06/02/2014, 20:27

... youth-friendly services, and policy dialogue and advocacy School and livelihood opportunities complement and reinforce these approaches Table Effective YRH Program and Policy Actions Program and Policy Action ... feels, and can in relation to healthy development and HIV/AIDS-related prevention • Focuses on risks that are most common to the learning group and with responses that are appropriate and targeted ... broader situation assessment • Has training and continuous support of teachers and other service providers • Uses multiple and participatory learning activities and strategies • Involves the wider community...

Ngày tải lên: 14/02/2014, 14:20

... includes electrical machinery and equipment and parts thereof; sound recorders and reproducers, television image and sound recorders and reproducers, and parts and accessories of such articles ... Emirates, Qatar, and Bahrain), Australia, Iceland, Norway, Switzerland, and the Southern African Customs Union (which includes South Africa, Botswana, Lesotho, Namibia, and Swaziland) In May 2012, ... credit and liquidity, and merchandise trade and current account surpluses “Unbalanced development” was described as economic disparities between rural and urban areas, regions of the country, and...

Ngày tải lên: 20/02/2014, 20:20

... Integration Center, and was conducted within RAND Arroyo Center’s Force Development and Technology Program RAND Arroyo Center, part of the RAND Corporation, is a federally funded research and development ... and those resources redeployed to focus on COIN and SSTRO Some of the trajectories explored in this study, namely “Expanding Scope” and “Chronic Insurgencies,” might imply considerable size and ... theater- and longer-term specific knowledge of areas and cultures; language skills; unconventional warfare and counterterrorism capabilities; tactical to strategic IO integration and development; and...

Ngày tải lên: 06/03/2014, 20:20

... 1998 and 2001 are taken from Zhang and Liang (2006); Data for Vietnam are adapted from Nguyen Thi Kim Anh and Pham Thi Hoang Oanh (2007) for 1998, 2001 and 2004, and are estimated for 2007 and ... purposes, see Fforde and de Vylder (1996), Nguyen Duc-Tho and Bandara (1994), Nguyen Tri Hung (1999), Vo Tri Thanh et al (2000), Pham Do Chi and Le Viet Duc (2003), Vo Dai Luoc (2004), and Pham Xuan ... one-half of the width of the band Historical data show, however, that it tended to increase slowly and sometimes did not increase at all Allowable trading band The trading band, within which commercial...

Ngày tải lên: 07/03/2014, 18:20

... Psychological and modifiable Sociodemographic and somewhat modifiable Biological and not modifiable Figure A gender and health model that exemplifies how health education researchers and practitioners ... examined to better understand gender and its relation to health At the conceptual level, it is argued that gender is a multidetermined construct and needs to be conceptualized and measured as such ... furthering science, understanding etiology, and testing promising interventions Gendered Selves To understand the possible causal role that gendered psychological and social attributes may play...

Ngày tải lên: 14/03/2014, 21:20

... terms on those accounts In addition to lenders, potential landlords and employers may review credit histories and/ or credit scores Landlords may so to determine if potential tenants are likely ... state legislatures and insurance commissions Thus, a consumer’ credit record and corresponding credit score can determine access s and pricing for the most fundamental financial and consumer services ... insurers, landlords, utility companies, and employers, who review the credit information in consumers’credit reports to make decisions about extending and pricing credit, offering and pricing...

Ngày tải lên: 15/03/2014, 07:20

... between TM helices and and between TM helices and provide noncovalent interactions with sites on the NBD These latter two linker regions, called intracellular loops and (ICL1 and ICL2) can both ... of cross-linking data and ligand docking, chiefly because of the NBD–TMD reverse domain order, the lack of conserved structural motifs ICD2 and ICD3, and shorter TMD helices and low sequence identity ... pair of motions to align the NBDs, thus forming the nucleotide sandwich dimer, and a concomitant retraction of TM1 and TM2 from TM3 and TM6, generating an outward facing configuration of the TMDs...

Ngày tải lên: 22/03/2014, 21:20

... organisms and organelles Some eukaryotes (land plants and various protists) use the multicomponent System I [also called the cytochrome c maturation (Ccm) system], and others (animals, fungi, and many ... in ball and stick representation, as are the methionine and histidine side chains that coordinate the heme iron, and the cysteine side chain that forms a thioether bond between heme and protein ... (actually AAQCH) heme-binding motif, and the sulfur of Met91 The ˚ heme iron–ligand distances were restrained to A (his˚ (methionine), and the model fits well tidine) and 2.3 A with these values The...

Ngày tải lên: 23/03/2014, 04:21

... monetary, and industrial policies; on the quality and quantity of human resources; on progress in science and technology; and on the global economy through trade and capital flows Andrew F Krepinevich, ... pursue science and innovation, and build capabilities and alliances to pursue interests shared with other countries and peoples; • the United States seeks an international order and cooperation ... winners and losers”; and • imbalances in trade and capital flows were largely self correcting (foreign exchange rates determined by capital markets and appropriate government fiscal and monetary...

Ngày tải lên: 23/03/2014, 21:20

... like meal preparation and cleaning; life management such as shopping, money management, and medication management; and transportation The services include hands-on and stand-by or supervisory ... long-term care policy— financing, delivery, and workforce and identifies some of the major demographic and policy trends that will affect the demand for, and supply of, long-term care in the future ... nursing and supervised custodial care, and “home care,” which includes personal services like bathing, dressing, and toileting as well as housework such as meal preparation and laundry WHO NEEDS AND...

Ngày tải lên: 28/03/2014, 17:20