mathematical modelling of tissue invasion

... model of the urea cycle was previously written by one of us (P W Kuchel) [10], but aspects of channelling and the effects of subcompartmentation of the cycle were not explored Hence, the aims of ... Simulating the effect of the addition of mM unlabelled arginine on the distribution of radioactivity in cytoplasmic intermediates of the urea cycle As the pattern of distribution of radioactivity ... effect on this labelling pattern of the addition of a 1-mM excess of arginine From a modelling point of view, this was accomplished by creating a separate ÔpoolÕ of exogenous arginine (called ÔargQÕ...

Ngày tải lên: 08/03/2014, 08:20

... studies on mathematical modelling of diffusion of factors, modelling of tortuosity due to extra cellular geometry and imaging studies of long range profiles of morphogens are highlighted Chapter details ... percentage of neurosphere forming units (NFUs; number of neurospheres/total number of cells) present in a cell population derived from neurosphere culture is a measure of the number of NSCs present ... no aggregation x List of Symbols Cellular doubling time of 20 hours t, cumulative time of culture , fraction of initially seeded dividing cells, 0.01412 N0, number of initially seeded cells...

Ngày tải lên: 10/11/2015, 12:28

... interest and meaningful suggestions of Professor T.-Y Na and Dr D A S Rees, the reviewers of this work Secondly, the formatting of this book and the preparation of the figures were performed by ... radius of cylinder or sphere, or major axis of elliptical cylinder, or body curvature, or amplitude of surface wave radius of core region reactant transversal heat dispersion constant amplitude of ... corresponding to the theory of hydrostatic equilibrium This leads to the process of the redistribution of the density which takes on the character of a continuous mutual substitution of fluid elements...

Ngày tải lên: 01/04/2014, 10:51

... undertook modelling of these data to understand better the transmission dynamics of the 1918 influenza pandemic in New Zealand Methods Data The population of the Featherston Military Camp was that of ... proportion of the population susceptible (Pis) Proportion of infected cases who develop symptoms (Pids) Infectivity of asymptomatic/infectivity of symptomatic people (Infas) Proportion of symptomatic ... mathe- Page of (page number not for citation purposes) Theoretical Biology and Medical Modelling 2006, 3:38 matical model (GS, MR) GS did most of the drafting of the first draft of the manuscript...

Ngày tải lên: 13/08/2014, 16:21

... (a) The ACF of {εI (n)} and that of {φI (n)} in Star Wars IV (b) The ACF of {εP (n)} and that of {φP (n)} in The Silence of 1 the Lambs 125 63 The ACF of {A3 (ε)} ... the base layer of the spatially scalable The Silence of the Lambs coded at different Q 118 57 The mean sizes of P and B-frames of each GOP given the size of the corresponding ... as a function of enhancement rate RE (neither of which requires any information from the base layer) The big advantage of using DE instead of D is that the statistical properties of DCT residue/coefficients...

Ngày tải lên: 06/11/2012, 10:45

... the light of the work of Kihara, of Waldmann, of Grad and of Hirschfelder, Curtiss and Bird A few minor changes of notation have been made; these are set out at the end of the list of symbols ... the sum of the products of corresponding components of w and w' In particular, w: w is the sum of the squares of the components of w, and U: U = From these definitions it follows that each of the ... direction of finding approximate solutions of the Boltzmann equation in regions having a thickness of the order of a mean free-path These new solutions were, of course, beyond the reach of the methods...

Ngày tải lên: 13/02/2014, 23:20

... formation of an alkaline phosphatase frame-shift mutant Hypophosphatasia is an inborn error of metabolism characterized by defective mineralization of hard tissues and reduced levels of tissue nonspecific ... assembly of TNSALP in the endoplasmic reticulum (ER), resulting in the loss of functional TNSALP from the cell surface [10–14] Deletion of T at position 1559 of the cDNA [TNSALP (1559delT)] of the ... concerted action of nucleoside triphosphate pyrophosphohydolase and TNSALP regulates local concentration of inorganic pyrophosphate at the site of mineralization, which, as a poison of hydroxyapatite...

Ngày tải lên: 19/02/2014, 17:20

... lexical feature type is larger than that of part -of- speech feature type, and the predictive information quantity of partof-speech feature type is larger than that of the constituent label feature type ... headword of the node In the following, the units of PIQ are bits z Conclusion Among the feature types in the same structural position of the parsing tree, the predictive information quantity of lexical ... a number of interesting conclusions on the predictive power of various feature types and feature type combinations, which is expected to provide reliable reference for the modelling of probabilistic...

Ngày tải lên: 20/02/2014, 18:20

... artefact of recombinant production because a similar low rate of substitution of recombinant perlecan domain V correlated well with a comparable low rate of modi®cation of two tissue forms of perlecan ... levels of laminin c1 chains in EDTA/detergent extracts of various mouse tissues The content of b1 chains in these extracts exceeded the content of b2 by a factor of 5±20 The relative amounts of b2 ... 20%) of such inhibition assays [36], in most cases in good agreement with the sum of b1 and b2 chains It served therefore as an internal control for the quality of the data Tissue extracts of mice...

Ngày tải lên: 21/02/2014, 03:20

... the process of model validation Owing to problems of observational undersampling of marine systems data are often insufficient when used for model validation Validation of models often amounts ... at modelling of the yearly cycle of nutrients and plankton in a simplified boxlike system, that may serve as a crude first order description of a part of a marine system, such as a sub-basin of ... total loss of phytoplankton fraction of Lp recycled in the upper box fraction of Lp sinking down into the lower box loss of zooplankton fraction of Lz recycled in the upper box fraction of Lz sinking...

Ngày tải lên: 06/03/2014, 18:21

... outputs of the submodels are aggregated by taking a weighted average of them The working point model defines the degree of membership of each model, which equals the weight of the submodel /19/ 12 MODELLING ... Dynamic simulation Dynamic fuzzy modelling can be performed based on state-space modelling, input-output modelling or semi-mechanistic modelling Input-output models are often used when models are built ... the old value of the simulated variable and the current value of the control variable are used as inputs and the new value of the simulated variable as an output In dynamic modelling of the linguistic...

Ngày tải lên: 08/03/2014, 23:20

... full recovery of plastic deformation [8, 9] I NTRODUCTION 1.3 Molecular background Independent of the stress level or amount of deformation involved, the origin of the deformation of polymer materials ... mechanism in the range of temperatures and strain rates of interest A linear dependence of yield stress as a function of log strain rate can be observed over a large interval of strain rates and ... P (1940) A study of polymers III Technique of mechanical tests of vulcanizates of rubber and plastics Rubber Chem Tech., 13, 904–917 Haward, R.N (1942) Extension and rupture of cellulose acetate...

Ngày tải lên: 09/03/2014, 00:20

... cardinal of the set of & for L is bounded by 2card(d(L))( d ( L ) is a n automaton f o r L ) proof A word of V, ( n 1) is a suffix of a word of L A set V, can be represented by a set of states of ... The Mathematical Foundation of Informatics This page intentionally left blank The Mathematical Mathematicalal a al Foundation of Informatics I Proceedings of the Conference 25 ... the number of neighbors of i, it is equal to N i , Proeesses Every process of the distributed systems executes the same code The program consists of a set of variables and a finite set of rules...

Ngày tải lên: 15/03/2014, 12:20

... potent use of this method, and validation of its efficiency, is in the modelling of the effect of impurities upon morphology of crystallites, a recent successful example being the work of Fleming ... characterisation of any hypothetical zeolite must therefore include an analysis of framework topology and of the types of building unit present, as well as some estimate of the thermodynamic stability of the ... structural modelling and the new and exciting field of simulations of zeolite surfaces The next three chapters focus on the modelling of sorbed molecules in zeolites Chapter describes the state -of- the-art...

Ngày tải lên: 15/03/2014, 18:20

... defective osteogenesis with various degree of failure in mineralization of hard tissues such as bone and tooth [1–3] Various mutations in the human tissue- nonspecific alkaline phosphatase (TNSALP, ... forms of the wild-type, which migrates on the SDS gel as the 66 kDa or 80 kDa form To address the question of whether the replacement of arginine at position 433 affects the catalytic function of ... amount of the 80 kDa noncross-linked form, over a wide range of expression conditions (Fig 4) Induction of TNSALP(R433C) was found to be regulated tightly, as no band was observed in the absence of...

Ngày tải lên: 16/03/2014, 12:20

... levels of crabp1b transcripts may be below the level of sensi3566 tivity of detection by the technique of tissue section in situ hybridization Discussion The differentiation and development of primary ... cord and ventral part of anterior myotomes (Fig 5H,J,L) Tissue- specific distribution of crabp1a and crabp1b mRNA in adult zebrafish Fig Comparison of the syntenic relationship of the zebrafish crabp1 ... single product corresponding to the position of the 7-methyl G cap of the mature crabp1a mRNA (data not shown) Alignment of the nucleotide sequence of the cloned 5¢-RLMRACE product with the genomic...

Ngày tải lên: 16/03/2014, 22:20

... course of the N/V stress shift, and can thus be seen as possible sources of the diachronic dynamics of N/V pairs.5 This type of assumption is necessary for any hypothesis about the sources of a ... Table lists which of Models 1–5 show each of the desired properties (from §3.2), corresponding to aspects of the observed diachronic dynamics of N/V pair stress Based on this set of models, we are ... (αt+1 , βt+1 ) Dynamical systems We develop and analyze models of populations of language learners in the mathematical framework of (discrete) dynamical systems (DS) (Niyogi and Berwick, 1995;...

Ngày tải lên: 17/03/2014, 00:20

Ngày tải lên: 17/03/2014, 14:03

Ngày tải lên: 17/03/2014, 14:36

... ingredients of cosmological models solely because of the role of the Higgs mechanism in electroweak unification Most accounts of the formation of cosmic strings offer only a heuristic explanation of the ... the evolution of the string network is driven principally by the gradual radiative decay of closed loops of string which break off from the network as a result of self-intersections of long (horizon-sized) ... the basis of the Nambu equations of motion, and anti-rigid if the correction terms act to enhance the curvature of the world sheet Numerical simulation of the collapse of a circular loop of string...

Ngày tải lên: 17/03/2014, 14:48