lost on the moon activity answers
Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
Ngày tải lên :
19/02/2014, 12:20
... proposed for the binding of the SRL to the
active site of RTA in which the principal difference lies in the
conformation of the second ÔGÕ in the target GAGA motif
in the 28S rRNA substrate. In one model, ... of RTA resulted in different effects on the
activity of RTA. Whereas, one had no effect on the activity
of the enzyme (R258A), others reduced activity by one
(R213A, R258D, R48A) or by two (R213D) ... hydrogen bonds to be formed between the
base G
4
and the sidechain of Asn122. In the second model
(Fig. 1B) the structure of the hexanucelotide is, on the
whole, unchanged and the majority of the interactions...
- 10
- 616
- 0
Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt
Ngày tải lên :
21/02/2014, 03:20
... to the iron(III) of Fe(ToCPP)
and Fe(ToCPP))13G10
The second part of our results concerns the binding of
imidazole d erivatives on the iron of Fe(ToCPP) either alone
in solution or inside the ... this
inhibition was due to the binding of the imidazole ligand
on the iron atom. In addition, measurement of the kinetic
parameters for the oxidation of ABTS by H
2
O
2
catalyzed by
Fe(ToCPP))13G10 in the ... (Table 1). The bind-
ing of the ®rst CN
±
ligand to the iron was thus more easy in
the hydrophobic binding pocket of the antibody than the
binding of the second one, most probably because of the
steric...
- 11
- 470
- 0
Tài liệu The Influence of Human Activity on the Environment ppt
Ngày tải lên :
26/01/2014, 10:20
... rise.
ã This leads to disruption of
the weather patterns eg
drought, floods
ã Some weeds may thrive on
the extra carbon dioxide
while other plants are killed
Biological Control of Pests
ã This ... from the
water
ã This means the fish
suffocate and die
ã This process is called
Eutrophication
ã Raw sewage pumped into
rivers has the same
effect
The Influence of Human Activity on the ... cars and power stations produces
carbon dioxide, sulphur dioxide and other greenhouse
gases
ã carbon dioxide traps heat in
the atmosphere and causes
the temperature of the
earth to rise.
ã...
- 23
- 690
- 0
Báo cáo khoa học: Effect of annealing time of an ice crystal on the activity of type III antifreeze protein pdf
Ngày tải lên :
07/03/2014, 05:20
... that the TH value
reflects the fraction of ice-bound AFPs on the flat ice
plane. Indeed, TH increases in proportion with the
total concentration of nfeAFP8, as can be seen in
Fig. 3A. The fraction ... AFP based on the
‘adsorption–inhibition’ model [3,4]. (A) A
convex ice front is created after primary
binding of type III AFP onto the flat ice
plane. (B) Overgrowth of the convex ice
front, giving ... value. (C) Possible
secondary ice binding of type III AFP onto
the convex ice front during the annealing
period (2–3 h). (D) AFPs bound onto the
convex ice front narrow the growth area
(dashed...
- 8
- 520
- 0
Báo cáo khoa học: Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases pot
Ngày tải lên :
22/03/2014, 16:20
... inhibition potency on
the polymerase function; and (c) the K-61 analogue
showed a fourfold reduction in its RDDP activity inhi-
bition potency. By contrast, when the AQ derivatives
were tested on the ... similar conformation (RMS 0.57), on
the other hand, in the crystal reported by Pata et al. [30]
the NNRTI binding pocket most closely resembles the
RT unliganded conformation. Therefore, the AQ ... steric modifications occur. The binding mode
of K-49 in the Y181C RT is different, and the contribu-
tion of the p–p stacking interaction is lost. Furthermore,
the low number of good contacts with...
- 14
- 425
- 0
Báo cáo khoa học: Effect of heliquinomycin on the activity of human minichromosome maintenance 4/6/7 helicase pdf
Ngày tải lên :
23/03/2014, 04:21
... both the ini-
tiation and elongation of DNA replication [13], and
these proteins migrate on the genome together with the
replication forks [14,15]. One of the intricacies related
to the function ... solution (0.4 lL) containing or lacking
heliquinomycin was added to the reaction mixture. The final con-
centrations of heliquinomycin added to the reaction mixture are
indicated at the top. The ... DNA was considered to be
100% in the control reaction mixture lacking heliquinomycin, and
the proportions in the mixtures containing heliquinomycin were cal-
culated in relation to the control...
- 10
- 538
- 0
Báo cáo khoa học: Effect of magnesium ions on the activity of the cytosolic NADH/cytochrome c electron transport system pptx
Ngày tải lên :
23/03/2014, 06:20
... Fig. 1 on the oxidation of exo-
genous NADH as the expression of the activity of
the complete system.
Discussion
The data presented provide new insights into the role
of magnesium ions in the permeability ... provides direct evidence that, in
these latter conditions, the addition of magnesium
mimics the results obtained with the addition of
cyto-c, the only difference being that the potential
is lower and ... mitochondria, activates the oxida-
tion of extramitochondrial NADH and the generation of a membrane
potential, both linked to the activity of the cytosolic NADH/cyto-c electron
transport pathway. The...
- 12
- 441
- 0
Báo cáo khoa học: The ‘pair of sugar tongs’ site on the non-catalytic domain C of barley a-amylase participates in substrate binding and activity potx
Ngày tải lên :
23/03/2014, 07:20
... agreement with the
reduced DMA of the AMY1 Y380A ‘sugar tongs’
mutant, these effects may stem from allosteric regula-
tion.
The mutational analysis of the ‘sugar tongs’ in barley
AMY1 explored the role ... This
is the first demonstration of a function for a C domain
from the large GH clan-H. The work contributes to the
unraveling of the molecular basis of multivalent
enzyme–polysaccharide interactions. ... connects b5 and a5 of the catalytic (b ⁄ a)
8
-barrel
at the end of the aglycon-binding area of the active site
cleft. Earlier, significant deviation was found in this
region between the backbone...
- 13
- 385
- 0
Báo cáo khoa học: The antibiotic activity of cationic linear amphipathic peptides: lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes doc
Ngày tải lên :
23/03/2014, 17:21
... by
spreading on agar plates cells treated for 2 h with different
peptide concentrations. The minimal lethal concentration
was defined as the lowest peptide concentration capable of
killing 99% of the cells ... No activity at concentrations £ 100 l
M
.
Ó FEBS 2003 Antibacterial activity of LK peptides (Eur. J. Biochem. 270) 2209
of action based upon the invasion of the outer membrane
leaflet by the ... flat orientation should thus be considered the
most stable one for LK peptides, even if other orientations
are possible (see below). As suggested by the ÔcarpetÕ model,
aggregation on the membrane...
- 11
- 330
- 0
Báo cáo khoa học: On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus pptx
Ngày tải lên :
28/03/2014, 23:20
... molecular
interface in the case of the former helicase. Further-
more, the absence of the S259 OH group in the
mutated viral enzyme prevents the formation of one
hydrogen bond with bananin, accounting for the
reduced ... accession number AY304495) on fetal rhesus
monkey kidney cell line FRhK-4 in the presence of
high concentrations of this adamantine derivative. The
half maximal effective concentration of bananin on
these ... protein, only second-
ary structure predictions can be obtained, limiting a
detailed structural interpretation of the functional roles
of A68V and R124W mutations. blast analysis on the
19 complete...
- 7
- 352
- 0
Báo cáo khoa học: Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4 doc
Ngày tải lên :
31/03/2014, 09:20
... tryptophanyl substitution at position 16 on the
biological activity was confirmed for the native GGN4.
Consistent with the results of the C-terminally truncated
GGN4, the D16W substitution in the native GGN4 ... contrast,
neither the D16F nor K15W substitution of the D
24)37
GGN4 allowed such a dramatic recovery of activity. In
addition, the D16W substitution of the native GGN4
significantly enhanced the ... that the D16W substitution of D
24)37
GGN4 contributed to the restoration of the antimicrobial
activity, at least by changing its structure.
In order to elucidate the structure-function relationship
of...
- 8
- 447
- 0
