... structure of apo-CRP has not yet been elucidated Therefore, we decided to study the changes in the apo-CRP structure induced by binding of cAMP and DNA by measuring uorescence resonance energy transfer ... revealed that binding of cAMP induces not only changes in the immediate environment of the cAMP-binding site but also far-reaching conformational changes (perturbation of chemical shift of Trp13) ... previously [15] but with one modication After ion-exchange chromatography on Q-Sepharose, the proteins were additionally puried by gel ltration on Sephacryl S-200 HR After this procedure, the proteins...
Ngày tải lên: 20/02/2014, 23:20
... (2003) Kinetic studies of 1115 CRP conformational changes induced by DNA and cAMP 19 20 21 22 23 24 25 26 27 28 29 30 31 cAMP -induced allosteric changes in T127I, S128A and T127I S128A mutants ... for conformational signal transduction in the 1111 CRP conformational changes induced by DNA and cAMP CRP(cAMP)2 complex after binding specic DNA, which occurs from the C-terminal domain to the ... dynamic entity FEBS Journal 272 (2005) 11031116 ê 2005 FEBS M Tworzydo et al CRP conformational changes induced by DNA and cAMP Results Steady-state uorescence quenching studies The uorescence quenching...
Ngày tải lên: 07/03/2014, 16:20
báo cáo hóa học: " A pilot study on pupillary and cardiovascular changes induced by stereoscopic video movies" pptx
... control, the parameters of the pupil were measured after the rest of in the dark room After presentation of movies, they were measured just after presentation in the dark room Then the difference ... movies The CR increased significantly after presentation of two CG movies, and the change was not significant after presentation of the movie R (Tables 1) Because changes in baseline pupil diameters ... Methods, presentation of motion pictures), changes in the CR might be induced by accumulation of the activities in the brain stem possibly due to the unnatural changes in the disparity and/or brightness,...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo khoa học: "Radiation recall pneumonitis induced by chemotherapy after thoracic radiotherapy for lung cancer" potx
... proliferative changes induced by radiotherapy might affect the subsequent pharmacokinetics of the inciting drug [28] Another is that after radiotherapy permanent changes had been induced in stem ... determining the occurrence of RRP The total normal lung volume was defined as the total lung volume minus the primary gross target volume (GTV) and volume of the trachea and main bronchi The following ... radiotherapy, (B) one month after end of radiotherapy, (C) months after end of radiotherapy when RRP took place induced by consolidation chemotherapy, and (D) days after application of systematic...
Ngày tải lên: 09/08/2014, 09:20
báo cáo khoa học: " Transcriptomic changes induced by acute ozone in resistant and sensitive Medicago truncatula accessions" pps
... point (Figure 3) In JE154, the changes in number of induced genes was opposite to that in Jemalong, with maximal induced genes observed early in treatment and fewer changes at the end of ozone treatment ... of changes in gene expression in response to acute ozone treatment using the ozone-sensitive Jemalong and ozone-resistant JE154 accession Time points selected were one, six, and twelve hours after ... ROS burst was observed in Jemalong 12 hours after initiation of treatment (Figure 1) High levels of ROS were maintained in Jemalong up to 24 hours after treatment initiation ROS levels in JE154...
Ngày tải lên: 12/08/2014, 05:20
Báo cáo y học: "Ability of pleth variability index to detect hemodynamic changes induced by passive leg raising in spontaneously breathing volunteer" pps
... automatically and noninvasively detect changes in ventricular preload induced by PLR in spontaneously breathing volunteers • Changes in preload induced by PLR also induced changes in PI However, PI was ... Moreover, it has been demonstrated to decrease significantly after PLR in spontaneously breathing volunteers, Figure Changes in PVI after changes in body position PLR, passive leg raisposition ing; ... than 12.5% [13] increase in CO after PLR Statistical analysis All data are presented as mean ± standard deviation Changes in haemodynamic parameters induced by changes in loading conditions were...
Ngày tải lên: 13/08/2014, 10:20
Báo cáo y học: "Giant liver hemangioma resected by trisectorectomy after efficient volume reduction by transcatheter arterial embolization: a case report" ppt
... patent (Figure 3A-C) Volumetric analysis revealed a tumor volume of 16,880 mL and a left lateral sector volume of 1250 mL Based on the liver function tests, remnant liver volume, and anatomic ... Page of Changes in the laboratory data and tumor volume are summarized in Figure Despite the blood counts becoming normal after TAE, fibrin degradation products (FDP) and D-dimer decreased after ... tumor volume The timing for the radical surgery after TAE is another problem in the management of huge liver hemangioma Considering the vascular recanalization and various complications after...
Ngày tải lên: 11/08/2014, 03:21
Báo cáo y học: "Giant liver hemangioma resected by trisectorectomy after efficient volume reduction by transcatheter arterial embolization: a case repor" pps
... patent (Figure 3A-C) Volumetric analysis revealed a tumor volume of 16,880 mL and a left lateral sector volume of 1250 mL Based on the liver function tests, remnant liver volume, and anatomic ... Page of Changes in the laboratory data and tumor volume are summarized in Figure Despite the blood counts becoming normal after TAE, fibrin degradation products (FDP) and D-dimer decreased after ... tumor volume The timing for the radical surgery after TAE is another problem in the management of huge liver hemangioma Considering the vascular recanalization and various complications after...
Ngày tải lên: 11/08/2014, 07:20
Báo cáo y học: "Changes in stroke volume induced by passive leg raising in spontaneously breathing patients: comparison between echocardiography and Vigileo™/FloTrac™ device" docx
... 30 40 PLR -induced changes in SV-TTE (%) Relation between PLR -induced changes in SV-TTE and SV-Flotrac SV-Flotrac Relation between passive leg raising (PLR) -induced changes in stroke volume measured ... between changes in SV-TTE and changes in SV-FloTrac The correlation between PLR -induced changes in SV-TTE and SV-Flotrac was r2 = 0.56 (P < 0.0001) and the correlation between VE -induced changes ... baseline were sub-normal and PLR induced significant changes in SVR only in Rs Figure 100 Sensitivity (%) 80 60 40 PLR -induced changes in SV-TTE PLR -induced changes in SV-FloTrac 20 0 20 40 60...
Ngày tải lên: 13/08/2014, 20:21
báo cáo hóa học:" Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood " pot
... P27) 1.9 interferon -induced protein 35 5.0 Interferon -induced protein 44, p44 8.4 interferon -induced protein 44-like 2.2 interferon induced with helicase C domain 4.8 interferon -induced protein with ... gene responses into four categories: genes that are induced early and once induced are induced throughout the trial period, genes transiently induced, those that appear late and down regulated ... interferon -induced protein with tetratricopeptide repeats 1.8 interferon -induced protein with tetratricopeptide repeats 1.7 interferon induced transmembrane protein (9–27) 2.0 interferon induced...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Non-monotonic changes in clonogenic cell survival induced by disulphonated aluminum phthalocyanine photodynamic treatment in a human glioma cell line" pot
... generally shrink and are associated with changes in cytoskeletal structure, which is reflected in the alterations of light scatter Therefore, treatment induced changes in forward and side scatter ... delay), and would, thus, include modifications induced by the late repair and death processes Also stress -induced premature senescence (SIPS), after sub-lethal oxidative damage [47,48], could ... Apoptosis Detection and analysis of photodynamically induced apoptosis was performed by studying the morphological features, DNA content and changes in cell size, cytoskeleton structure associated...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo khoa học: " Changes of gastrointestinal argyrophil endocrine cells in the osteoporotic SD rats induced by ovariectomy" ppt
... and osteoporosis induced by ovariectomy or post-menopause is directly related to some endocrine system especially to estrogen [19,20] The purpose of this study is to observe the changes of regional ... endocrine cells in a postmenopausal osteoporotic rat induced by ovariectomy In this study, each part of GI tract is sampled at 10th week after ovariectomy or sham-operation Material and Methods ... quantity analyses After phlebotomy, each region of GI tract, fundus, pylorus, duodenum, jejunum, ileum, cecum, colon and rectum was collected from all experimental animals at 10th week after ovariectomy...
Ngày tải lên: 07/08/2014, 17:23
Báo cáo khoa học: "Changes in dry weight and nitrogen partitioning induced by elevated CO depend on soil nutrient 2 availability in sweet chestnut (Castanea sativa Mill)" ppt
... chestnut stand; it consisted of the upper 15 cm organic layer of forest soil sifted and homogenized after litter removal The main soil characteristics were as follows: ; apparent density: 1.5 g.cm ... pot) Total leaf per tree was computed by length (L) and width (W) of all leaves (S L x W x 0.65) After leaf fall, all dead leaves were collected and weighed Later, in January, the plants were dug ... leaf) nitrogen content is mentioned in table II because the analyses were performed in winter, after leaf fall and nitrogen redistribution to other plant parts The analysis made on a few green...
Ngày tải lên: 08/08/2014, 23:22
Báo cáo y học: " Near fatal posterior reversible encephalopathy syndrome complicating chronic liver failure and treated by induced hypothermia and dialysis: a case report" pps
... currently listed for liver transplantation Discussion We believe that this is the first documented case of PRES associated with cirrhosis as well as the first report of induced hypothermia for ... was considered contraindicated Moderate induced hypothermia has been shown to reduce cerebral edema following cardiac arrest and in patients with acute liver failure [15,16] The mechanisms by ... hypothermia in the prevention of brain edema in acute liver failure: mechanisms and clinical prospects Metab Brain Dis 2002, 17(4):445-451 The Hypothermia after Cardiac Arrest Study Group: Mild therapeutic...
Ngày tải lên: 11/08/2014, 17:21
Báo cáo y học: "Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines" doc
... tissue, DEX was added either two days before or two days after injury + cytokine treatment to test whether DEX could protect and/ or rescue changes in cartilage matrix metabolism caused by injury ... macroscopic tissue changes in human cartilage disks were similar (elliptical appearance) to those described previously using our human cartilage injury model and scoring system [36] After injury, ... biosynthesis induced by subsequent cytokine treatment, bovine cartilage disks (10 disks from a separate animal) were either pre-treated with DEX for two days or incubated in medium alone Afterwards,...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo khoa học: " Effects of volume resuscitation on splanchnic perfusion in canine model of severe sepsis induced by live Escherichia coli infusio" pdf
... large -volume crystalloid infusion fails to restore gut mucosal blood flow and PCO2 gap in animals challenged with infusion of live bacteria Hence, we evaluated the impact of this early volume ... between gastric mucosal and arterial PCO2 Experimental protocol After surgical preparation, animals were allowed to stabilize for 30 After baseline measurements (0 min), an infusion of E coli at ... changes Treated animals exhibited only a partial increase in mesenteric blood flow Fluid infusion was unable to restore the other regional variables PCO2 gap began to increase progressively after...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo khoa học: "Changes in aortic blood flow induced by passive leg raising predict fluid responsiveness in critically ill patients" ppsx
... this PLR maneuver induced ABF changes that were similar in magnitude to that observed after a VE of 250 ml This agrees with a previous study that showed a 300 ml shift in blood volume towards the ... In responders, the PLR -induced increase in ABF was similar to that induced by a 250 ml VE (16% (10 to 21%) versus 20% (1 to 30%), p = 0.15) The most discriminant value of changes in ABF that was ... http://ccforum.com/content/10/5/R132 Figure Figure Relationship between changes in ABF induced by PLR and VE AbbreVE viations: ABF = aortic blood flow; PLR = passive leg raising; VE = volume expansion Results are expressed as...
Ngày tải lên: 13/08/2014, 03:20
Báo cáo khoa học: "Effect of positive end-expiratory pressure and tidal volume on lung injury induced by alveolar instability" ppsx
... instillation of Tween (Baseline), after endotracheal instillation of Tween (Post-Tween), and every 30 thereafter for 180 minutes PEEP, positive end-expiratory pressure; Vt, tidal volume Microatelectasis ... ventilator -induced lung injury: a perspective J Appl Physiol 2000, 89:1645-1655 The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes ... of the lowest PEEP (5 cmH2O) with the highest tidal volume (15 cc/kg; Table and Figure 2b; also see Additional file 2) For any given tidal volume following Tween instillation, higher levels of...
Ngày tải lên: 13/08/2014, 03:20
Changes in cholesterol metabolome after kainate induced neurodegeneration
... Chapter 2.1 Changes in cholesterol biosynthesis after KA -induced neurodegeneration 53 Chapter 2.1 Changes in cholesterol biosynthesis after KA -induced neurodegeneration 2.1.1 ... following chapters 87 Chapter 2.2 Changes in cholesterol oxidation after KA -induced neurodegeneration 88 Chapter 2.2 Changes in cholesterol oxidation after KA -induced neurodegeneration Introduction ... damage upon KA -induced excitotoxicity Thus, this portion of study was performed to explicate the changes of these COPs in the hippocampus after KA -induced excitotoxicity 90 Chapter 2.2 Changes in...
Ngày tải lên: 10/09/2015, 08:32
Báo cáo y học: "Emulsified Isoflurane Preconditioning Reduces Lung Injury Induced By Hepatic Ischemia/Reperfusion in Rats"
... the lung Lung injury induced by hepatic I/R is thought of as a result of liver- derived TNF-α In fact, blockade of TNF-α by antibody neutralization greatly reduced hepatic I/R induced lung inflammatory ... 2007; 39: 361-364 Peralta C, Prats N, Xaus C et al Protective effect of liver ischemic preconditioning on liver and lung injury induced by hepatic ischemia-reperfusion in the rat Hepatology 1999; ... inhibits lipopolysaccharide induced acute lung injury in rats Inflamm Res 2005; 54: 133-137 Hato S, Urakami A, Yamano T et al Attenuation of liver and lung injury after hepatic ischemia and reperfusion...
Ngày tải lên: 25/10/2012, 11:00