linking inflammation to prostate cancer

... are known to suffer from lack of sensitivity (Cosnier and Holzinger, 2011) To enhance sensitivity, carbon nanotubes (CNTs) were frequently reported (Wohlstadter et al., 2003; Wang, 2005) to increase ... indicator with high sensitivity, ca 85 pM Very few works were related to label-free and reagentless biosensors Okuno et al (2007) described a label-free and reagentless immunosensor for prostate- specific ... immersed into 500 μL of a solution containing 150 mM EDC+300 mM NHS at 37 1C for h to activate the carboxyl group Then, electrodes were washed with distilled water and immersed into 500 μL of...

Ngày tải lên: 02/07/2014, 14:14

... immunohistochemistry (IHC) to stain for major histocompatibility complex (MHC) proteins in cervical tissue (Table 4) MHC class I molecules present endogenous antigens (cytoplasmic proteins) to cytotoxic ... ability to produce and secrete the inflammatory cytokine TNF- (Sakuishi, Apetoh et al 2010) At later time points of the persistent infection, the cells also fail to produce IFN- and lose their cytotoxic ... hypothesized to lead to HPV incidence, persistence, and progression to cervical precancer and cancer (Castle and Giuliano 2003) Studies that directly evaluate womens immune response to HPV infection...

Ngày tải lên: 07/03/2014, 20:20

... consultant to Algeta ASA Received: 17 January 2011 Accepted: June 2011 Published: June 2011 References Prostate cancer - UK incidence statistics [http://info.cancerresearchuk.org/ cancerstats/types /prostate/ incidence/#geog] ... shown increased diagnostic accuracy compared to 99mTc-MDP planar and/or single-photon emission computed tomography (SPECT) imaging in prostate and other cancers [13-18] PET also offers the inherent ... this method has not been used to monitor the treatment effects in bone metastases The purpose of this pilot study was to demonstrate the early treatment response to radium-223 ( 223 Ra)-chloride...

Ngày tải lên: 21/06/2014, 02:20

... prostate cancer interest in prostate cancer prevention has come to the forefront The Selenium and Vitamin E Cancer Prevention Trial (SELECT) is the largest chemoprevention trial in prostate cancer ... limiting the toxicity to adjacent organs New systemic and vaccine therapies have most recently emerged as effective approaches to advanced disease Prostate cancer screening Prostate cancer screening ... Alberto Pérez-Rozos Chapter 17 Paradigm Shift in the Concept of Hormonal Milieu of Prostate Cancer Tsutomu Nishiyama Chapter 18 The Role of Cancer Stem Cells and MicroRNAs in Human Prostate Cancer...

Ngày tải lên: 27/06/2014, 17:20

... EA: Local recurrence of prostate cancer in rectal submucosa after transrectal needle biopsy and radical prostatectomy Urology 2005, 66:881 Lane Z, Epstein JI, Ayub S, Netto GJ: Prostatic adenocarcinoma ... metastatic prostate cancer Eur Arch Otorhinolaryngol 2006, 263(9):872-874 Gallee MP, Visser-de Jong E, van der Korput JA, van der Kwast TH, ten Kate FJ, Schroeder FH, Trapman J: Variation of prostate- specific ... different tumour growth patterns present in prostatectomy specimens Urol Res 1990, 18(3):181-187 Murray SK, Breau RH, Guha AK, Gupta R: Spread of prostate carcinoma to the perirectal lymph node basin:...

Ngày tải lên: 09/08/2014, 01:24

... bowel toxicity Thus, total Page of doses to lymph nodes are generally limited to below 60 Gy In the current study we could demonstrate that total doses to metastatic lymph nodes of up to 66,6 ... according to The Artificial Neural Networks in Prostate Cancer Project (ANNs in CaP; http://www.prostatecalculator.org) In case of pelvic lymph node irradiation, all pelvic lymph nodes up to the ... intermediate to high risk primary or recurrent prostate cancer received FEC - PET/CT planned radiotherapy with escalated boost doses to PET/CT positive lymph node sites Doses to lymph nodes of up to 66,6...

Ngày tải lên: 09/08/2014, 09:20

... later he went on to have external beam radiotherapy to his prostate (80 Gy in 39 fractions over weeks), achieving a good response without any side effects or symptoms Repeat CT prior to removal of ... into the pelvis to exclude small bowel from the pelvis to prevent injury from post-operative radiotherapy[8] Sugarbaker described covering the implant with a mesh which was sutured to the peritoneum ... or the abdomen to prevent radiation injury to small bowel (Table 1) All of these were inserted at open laparotomy Lasser first described its use prior to radiotherapy for rectal cancer [9] Many...

Ngày tải lên: 09/08/2014, 09:20

... (ANNs) are attractive analytical tools in medicine due to their ability to learn from historical examples, analyze non-linear data and being able to generalize a model to independent data ANNs are ... obtained and allowed to coagulate before being centrifuged and stored at -80°C until analysis Free and total PSA were assayed by the fluoroimmunonometric AutoDELFIA ProStatus™ PSA Free/Total kit (PerkinElmer ... controversies in the treatment of high-risk prostate cancer Curr Opin Urol 2008, 18:263-268 Barry MJ: Screening for prostate cancer the controversy that refuses to die N Engl J Med 2009, 360:1351-1354...

Ngày tải lên: 09/08/2014, 09:20

... radiation (64 to 66 Gy); or post high dose rate brachytherapy (50.4 Gy) Also collected were total beam time, total MUs per course and acute rectal toxicities as per the RTOG criteria [4] up to six weeks ... In our audit, 30 prostate cancer patients treated radically with RA by one radiation oncologist were found to be treated with acceptable toxicity In re-planning eight prostate cancer patients ... according to PTV coverage and the dose constraints for IM as detailed in Table Indication for radiotherapy, total beam times, monitor units and acute rectal toxicity of the first 30 prostate patients...

Ngày tải lên: 09/08/2014, 09:21

... appears prudent to minimize all factors that might contribute to non -cancer mortality in these patients Even if PMRT should be considered as just one of the potential factors contributing to cardiac ... Prostate Cancer Trialist Group: Bicalutamide ('Casodex') 150 mg as adjuvant to radiotherapy in patients with localised or locally advanced prostate cancer: results from the randomised Early Prostate ... skin and the outer contour of the heart and used the data from Table to estimate the heart dose The same methods were used to examine the first 17 patients with prostate cancer who were treated...

Ngày tải lên: 09/08/2014, 09:22

... modulated radiation therapy (IMRT) following prostatectomy: more favorable acute genitourinary toxicity profile compared to primary IMRT for prostate cancer Int J Radiat Oncol Biol Phys 49(2):465-72 ... possible factors related to acute toxicity, it was observed that a patient's personal history of systemic arterial hypertension was a significant risk factor for Grade or higher GI acute toxicity ... Table 4: Acute and late gastro-intestinal (GI) and genito-urinary (GU) toxicities profiles: Pre-treatment Acute Late GI RTOG G1 RTOG G2 RTOG G3 RTOG G4/G5 GU GI GU GI GU (2.4 %) 19 (15.2%) 54 (43.2%)...

Ngày tải lên: 09/08/2014, 10:21

... prostate cancer are more likely to have their death attributed to prostate cancer In this study, this bias could lead to overestimation of survival from non -cancer causes in men treated for prostate ... incidence of non -prostate cancer mortality unadjusted and adjusted for prostate cancer mortality Deaths from prostate cancer are a competing cause of mortality with non -prostate cancer deaths Figure ... prostate cancer survival censors deaths from non -prostate cancer and men who are still alive at the end of the study period The K-M non -prostate cancer survival censors deaths from prostate cancer...

Ngày tải lên: 09/08/2014, 10:21

... membrane localizations (Figure 2F to 2G and 2K to 2L), while Gli transcription factors were predominantly detected in the nucleus and cytoplasm (Figure 2H to 2J and 2M to 2O) Moreover, Hh signaling ... populations of prostate cancer cells (Figure 3A; (d)), similar to that observed in human prostate cancers [20] Hedgehog overexpression promoted P63+ basal/stem cell hyperplasia toward malignant ... overexpression P63+ basal/stem cells were transformed into AR+ or ARcancer cells but rarely into ChgA+ neuroendocrine cancer cells Conventional human prostate cancer cells include malignant cells of luminal,...

Ngày tải lên: 10/08/2014, 05:21

... 23.75% Pre- and post-treatment median total testosterone levels are shown in Figure 2B In contrast to the total serum testosterone levels, the PSA to testosterone ratio decreased in all the patients, ... for localized prostate cancer Technol Cancer Res Treat 2009, 8:387-392 Katz AJ, Santoro M, Ashley R, Diblasio F, Witten M: Stereotactic body radiotherapy for organ-confined prostate cancer BMC Urol ... localized prostate cancer In our study, we observed a small decline (23.75%) in total testosterone levels after SBRT treatment consistent with that reported by others [36] and similar to that seen...

Ngày tải lên: 10/08/2014, 21:23

... be taken not to disseminate cancer cells to the peritoneum during laparoscopic radical prostatectomy Introduction Peritoneal dissemination with no further metastases of prostate cancer is very ... peritoneal dissemination due to laparoscopic radical prostatectomy Case Presentation: A 59-year-old Japanese man underwent laparoscopic radical prostatectomy for clinical T2bN0M0 prostate cancer, ... peritoneal carcinomatosis in prostate cancer] Aktuelle Urol 2007, 38(5):408-409 Zagouri F, Papaefthimiou M, Chalazonitis AN, Antoniou N, Dimopoulos MA, Bamias A: Prostate cancer with metastasis to...

Ngày tải lên: 10/08/2014, 23:22

... laboratory techniques were still in their infancy Short term cell cultures of cancer tissues were difficult to perform and procedures varied from laboratory to laboratory However, the cancer ... growth factors, i.e their cell receptors as cancer biomarkers to develop new targeted anticancer drugs with better tumor response However, tumor concentrations of growth factor receptors not reliably ... are used to test tumor response to cancer drug therapy Tumor References Colorectal cancer Paraskeva C et al [9], Park J-G et al [10], Whitehead [11] Testicular Cancer Pera MF [12] Skin cancer Parkinson...

Ngày tải lên: 25/10/2012, 11:10

... factor, which leads to cell cycle arrest for DNA repair or apoptotic cell death [41] Both mice and humans harboring germ line inactivating mutations in one p53 allele are highly susceptible to cancer: ... Population attributable risks of esophageal and gastric cancers J Natl Cancer Inst 2003;95:1404-1413 DeMarini DM: Genotoxicity of tobacco smoke and tobacco smoke condensate: A review Mutat Res 2004;567:447-474 ... susceptibility to esophageal cancer, even when stratified by subgroup This finding is perhaps not surprising, because the functional evidence to support the role of GSTP1 Ile105Val as an esophageal cancer...

Ngày tải lên: 25/10/2012, 11:40

... tumor recurrence rates after anatomical radical retropubic prostatectomy for prostate cancer J Urol 1994; 152: 1837-1842 Walsh PC The status of radical prostatectomy in the United States in 1993: ... transport into prostate cancer cells J Pept Sci 2009; 15: 235-241 Ehemann V, Sykora J, Vera-Delgado J, Lange A, and Otto HF Flow cytometric detection of spontaneous apoptosis in human breast cancer ... resolution flow cytometry is an appropriate tool not restricted to the monitoring of the therapeutic effect DNA aneuploidy, as determined with high-resolution flow cytometry, has been shown to be an excellent...

Ngày tải lên: 26/10/2012, 09:48

... childhood asthma could thus be to focus on factors aiding children with asthma to getting better over the years The aim of this study was to analyze possible factors related to the outcome in an Asthma ... diagnosis up to the age of seven, at the age of ten were reported to never have had asthma? The analysis was directed towards possible salutogenetic factors aiding children with asthma to recover ... attention has also been directed towards protective factors In allergic disorders this research has been focused upon factors that could enhance the development of tolerance to allergens which were previously...

Ngày tải lên: 26/10/2012, 09:48

... doctor may advise a prostate biopsy (see section, "How Is Prostate Cancer Diagnosed?") to find out if you have cancer Some doctors may consider using newer types of PSA tests (discussed below) to ... used The DRE can also be used once a man is known to have prostate cancer to try to determine if it may have spread to nearby tissues and to detect cancer that has come back after treatment Transrectal ... cryosurgery Signs and Symptoms of Prostate Cancer Early prostate cancer usually causes no symptoms and is most often found by a PSA test and/or DRE Some advanced prostate cancers can slow or weaken...

Ngày tải lên: 24/12/2013, 21:15