lessons learned and their relevance to the clinic

Ngày tải lên: 13/02/2014, 12:20

Ngày tải lên: 05/08/2014, 09:46

... and drafted the manuscript UR contributed to the conception and the design of the study TB acquired the data IK contributed to the analysis JK contributed to the intellectual content TG, MB and ... calculate the variance between the groups, i.e the deviation the Fourier approximation of the single groups and the Fourier approximation of the whole data If all groups show the same rhythm then the ... different nycthemeral rhythms, one describing crime rates on d6 and d7, the other on d1 to d5, see Figure for a plot of these two rhythms Now the “whiteness“ of the residuals of the fit of d1 to d5...

Ngày tải lên: 10/08/2014, 09:20

... children and newborns [21,22] To further analyse the specificity and significance of the antibody responses toward the two linear preS1 sequences that have been shown to represent human B cell epitopes ... whereas the N-terminal part is believed to play a major role in mediating virus attachment and entry into hepatocytes [3] Within the preS1 protein, the 21–47 amino acid epitope was shown to mediate ... of several preS1 epitopes, and in particular, the epitope contained within the second half of the hepatocyte binding site localised in the hepatitis B surface protein of the third-generation...

Ngày tải lên: 12/08/2014, 04:21

... narrow and is located closer to the random end than to the ordered end of the complexity scale Compression of an instructive sequence slides the FSC curve towards the right (away from order, towards ... deterioration in the same sense that the mathematical laws of physics transcend the dynamics they model The purpose of biomessages is to produce and manage metabolic biofunctions, including the location, ... on the opposite end of the bi-directional vectorial spectrum of complexity from RSC FSC is usually paradoxically closer to the random end of the complexity scale than the ordered end FSC is the...

Ngày tải lên: 13/08/2014, 23:20

... proven to be the most accurate and can ensure the accuracy and stability of the hybrid method After explaining the combination scheme of the TDFEM and PSTD, some numerical examples are given The ... The hybrid methods TDFEM-PSTD, PSTD-FDTD and FMM-PSTD developed in this thesis improve the accuracy of the traditional PSTD method and preserve the efficiency of the PSTD algorithm They help to ... this thesis In the three hybrid PSTD methods developed in this thesis, only the application of PSTD-FDTD method is extended to the 3D problems The applications of the TDFEM-PSTD method and the...

Ngày tải lên: 11/09/2015, 09:00

... Properties and their Relevance to Utilisation Physical properties of organic liquids The unit of rayl breaks down to: rayl = kg m-2s-1 and these are also the units of the product: density  velocity The ... proportions of toluene and oil and the refractive index plotted as a function of the composition of the mixture there can be extrapolation to obtain a value for the oil alone in the absence of toluene ... magnitude The interested reader can easily confirm that the answer to (a) is an increase to 324 K (51oC) The answer to (b) is an increase to 429K (156oC) 1.2.3 Extension to other organic compounds The...

Ngày tải lên: 09/03/2016, 10:21

... location of 20 methadone clinics including the study clinic and the district where the clinic is located ering in its vicinity than the clinic in the district where they resided As most respondents ... (55.6%) went to the clinic by walking and 30.2% by cycling, so they did not need to pay for their daily trip A minority (14.3%) had to pay for the transportation Using one-way ANOVA, there was no ... methadone clients on one hand, and the utilization of clinic services on the other, as exemplified by the situation in Hong Kong In interpreting the results in the study, there are two unique features...

Ngày tải lên: 11/08/2014, 18:20

... proteinases, and their function suggested to contribute to their allergenicity Thus, a proteinase function of group I allergens could explain the high prevalence of allergic individuals sensitized to these ... the genus Giardia are one of the earliest lineages of eukaryotic cells, and the Giardia protease is the earliest known branch of the cathepsin B family [23] Its phylogeny confirms that the cathepsin ... generated (Fig 1) The identity between Phl p and CP2 of Giardia within comparable regions was 21%, and the combined identity and similarity amounted to 34% The identity between Hol l and CP2 was ...

Ngày tải lên: 08/03/2014, 22:20

... discussion of these themes, he insightfully weaves together positions advanced by the contributors to this volume with respect to the science and policy of acid deposition To further the chemical and biological ... domestic institutions and actors in determining the extent to which CEE governments have been willing and able to bring their power plants into compliance with tough European standards The Czech Republic's ... going to be needed to reduce the levels of lake acidification, but the amounts of reductions, the costs of doing so, the regulatory mechanisms to be used, and the fact that the environmental Lessons...

Ngày tải lên: 16/03/2014, 11:43

... financing and in may cases they gather most of the details of their customers financial strength and of the transaction for the lender In other cases, the foreign buyer may take the lead in pursuing the ... Bank and the lender must approve of the fiscal strength of the borrower and the foreign buyers in order for the guarantee to be put in place There is no maximum limit to these loans and the term ... brother Jim, sister Jenn, and brother-in-law Steve, although all younger, earned their doctorates in their chosen fields before I started Their success inspired me My parents whose wisdom and...

Ngày tải lên: 03/06/2014, 02:14

... features and their correlation CLL subsets with distinct BCR features and their correlation with prognosis Question marks in parenthesis indicate data that has to be confirmed by further investigations ... CLL, or only to the cases expressing the same IGHV genes but without the same stereotyped BCR [89,92] Among the few M clusters that are shared by the majority/ totality of the datasets, there are ... occurring via the surface B cell receptor (BCR) and dependent on specific molecular features of the BCR itself and/ or on the presence of the BCR-associated molecule ZAP-70, or via other non-BCR-dependent...

Ngày tải lên: 18/06/2014, 15:20

... up to the labor inspectorate, the insurance scheme and/ or specialists in occupational medicine, to clarify the work-relatedness of the cancer case or disease and to determine to what extent the ... exposure history a Work- and exposure history The only way to identify the possible causes of a given case of cancer is to identify and to (semi)quantify workand environmental exposure in the past, ... trying to hurt the workplace of concern In Norway only a handful of work-related cancers, e.g a few mesotheliomas and nickel-related cancers, were notified to the labor inspectorate prior to the...

Ngày tải lên: 20/06/2014, 00:20

... co-editorship of Anke, Ihnat and Stoeppler, followed by action by the publisher to ask former members of the Editorial Advisory Board and a few new ones for participation and by the editors to discuss ... Elements and Their Compounds in the Environment Edited by E Merian (†), M Anke, M Ihnat and M Stoeppler Elements and their Compounds in the Environment 2nd Edition Edited ... Symbols and definitions), some general tabulated information, and an Index The editors wish to thank all contributing authors for their careful work and for compliance with the general editorial...

Ngày tải lên: 03/07/2014, 16:08

... according to their respective rating The good lots (good and moderate classes) produced the best %FSPC and the poor lots (poor and low classes) yielded the lowest %FSPC Comparing the viability ... (fig 3B) Also, the addition of 10B to the concentrations of PEG further lowered the proportion of Class grains but only at the higher levels of PEG For the 10P10B and 20P10B media, there was no ... Jett and Frampton, 1990) and conductivity (Webber and Bonnet-Masimbert, 1989) response The effect of preconditioning pollen by hydration or in vitro assay response and, therefore, in and the correlation...

Ngày tải lên: 08/08/2014, 23:22

... mouse IgG and IgM rheumatoid factor, not seen in the TTP KO mice The inflammatory bowel disease was severe and universal and affected both the colon and the terminal ileum in some cases The hemizygous ... in the TNF-α transcript for any of the three family members to bind to, whereas in the TTP KO mice the other two family members could bind to the TNF-α ARE and decrease its stability As the other ... positions of the zinc finger protein–RNA complexes are indicated by the bracket to the right of the gel, and the position of the free probe (FP) is also indicated The bands present in the gel in...

Ngày tải lên: 09/08/2014, 01:24

... from cotton and analyze their expression in different tissues to help define their physiological roles We also present an analysis of the consequences of over-expressing cotton GhCPS1, and in ... activity To test whether the identified GhCPSs have enzymatic activity, the genes were cloned into pYES2 vector and transformed into host strain YPH499 In addition to the authentic GhCPS2 sequence, ... 17:0 CFA and 19:0 CFA were calculated as a percentage of the total fatty acids The values represent the mean and standard deviation of three replicates and show high similarities to the published...

Ngày tải lên: 11/08/2014, 11:20

... of switching to ST and pharmaceutical nicotine and potential willingness to switch in the future, as well as to partially assess the informational barriers to switching Methods The research team ... the common beliefs and misperceptions about tobacco and nicotine that are reported in the literature or that we have observed in our experience as educators To assess the stated willingness to ... http://www.harmreductionjournal.com/content/6/1/14 and could be used without anyone noticing, with one reducing the health risks by 99% and the other by 50% The subjects were never told that the "hypothetical" 99%reduction...

Ngày tải lên: 11/08/2014, 18:20

... cingulate [29] and via the reticular activating system to the sensory cortex [30,31] The sensory cortex then directs information directly to the amygdala, or via the hippocampus and then to the amygdala ... projects to the lateral hypothalamus to mediate the activation of sympathetic component of the ANS [36]; projections to the dorsal motor nucleus of the vagus are involved in the activation of the ... project to association cortices, such as the parieto-temporo-occipital and prefrontal, and then to the transitional cortex, including entorhinal, parahippocampal and perirhinal areas of the limbic...

Ngày tải lên: 13/08/2014, 14:20

... which the LTR is active 3) The PHSC is notoriously difficult to transduce with oncogenic retroviral vectors and the protocol used was designed to enhance transduction by using multiple cytokines to ... with the vector However, the enhancing properties of the HIV-1 LTR in the presence and absence of Tat needs to be carefully defined in order to test the assumption that the HIV-1 LTR lacks the ... activates, the erythropoietin receptor resulting in massive erythroid proliferation and splenomegaly [34] However, p55 does not bind to the active site of the Epo receptor and the Epo receptor is...

Ngày tải lên: 14/08/2014, 19:22