... understanding of informed consent and the risks and benefits of the medical intervention[87] Following a validated systematic process minimizes physi- cian bias and standardizes the measurement of ... cultural competency and patient-centered training into the curriculum Such abilities are not innate, but rather, they can and should be continually refined and improved In the context of these matters, ... Euthanasia is, however, legal in some countries, including the Netherlands and Switzerland Interestingly, many individuals support widespread legalization of both euthanasia and physician-assisted...
Ngày tải lên: 13/08/2014, 23:20
... Conclusions, including the results of the November 2001 Workshop Management Framework - Introd uced Marine Pests Management capabilities and approaches APEC and the MRCWG have a role in liaising with ... Within APEC little is known on the introduction of marine pests Little practical information on measures to prevent introductions Lack of knowledge in what individual countries are doing ... NACA to enhance the effectiveness of existing instruments within APEC Institutional arrangements for managing the marine environment is fragmented in most economies Baseline surveys to identify...
Ngày tải lên: 28/10/2013, 11:15
Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered Vol 45 / No RR-4 MMWR and the vaccinee’s age at the time of vaccination ... resurgence in the incidence of TB occurred in the United States and included increases in the number of TB cases among adults and children and outbreaks of multidrug-resistant TB (MDR-TB) involving ... Control and Prevention The role of BCG vaccine in the prevention and control of tuberculosis in the United States: a joint statement by the Advisory Council for the Elimination of Tuberculosis and the...
Ngày tải lên: 15/02/2014, 13:20
Tài liệu Trends in the Fees and expenses of Mutual Funds, 2010 pptx
... basis points of the 11 basis-point decline in the average expense ratio of funds of funds over the period (labeled in Figure 13 as “Fall in expense ratios of individual funds”) By definition, the ... inflation by taking the fee breakpoints available in 2010 and multiplying by the Consumer Price Index in December 2000 and dividing by the Consumer Price Index in December 2010 The front-end ... endowments, and other institutional investors investing for their own accounts, rather than on behalf of retail investors Stock Funds The average fees and expenses paid by stock fund investors declined...
Ngày tải lên: 19/02/2014, 15:20
Tài liệu Trends in the Expenses and Fees of Mutual Funds, 2011 ppt
... declined in 2011 owing to declines in the expense ratios of individual funds, an increase in the demand for index funds, and a continuing shift by investors in both actively managed and index ... percentage of the assets that the financial professional manages for an investor, rather than as a percent of the dollars initially invested Over time, brokers and other financial professionals ... collects the 12b-1 fee, passing the bulk of it to the financial professionals serving fund investors Alternatively, investors may pay the professional an asset-based fee directly In such cases, the...
Ngày tải lên: 19/02/2014, 15:20
Tài liệu Rubber plantation performance in the Northeast and East of Thailand in relation to environmental conditions docx
... On the other hand, in the far Northeast, along the Mekong River, over 2030 mm is received annually Variation in the average amount of rainfall is therefore notable in the Northeast During the ... in Thailand, and the University of Helsinki This study was also a joint undertaking in the long series of academic collaboration between the universities of Kasetsart and Helsinki 1.2 Scope and ... Research Institute of Thailand (RRIT) and the Office of the Rubber Replanting Aid Fund (ORRAF) The RRIT works under the Department of Agriculture (Ministry of Agriculture and Cooperatives), and its...
Ngày tải lên: 21/02/2014, 04:20
Tài liệu recent trends in the law and policy of bioenergy production promotion and use docx
Ngày tải lên: 21/02/2014, 05:20
Tài liệu ‘Unheard voices’: listening to Refugees and Asylum seekers in the planning and delivery of mental health service provision in London. pptx
... ONE is the INTRODUCTION This includes an outline of the CONTEXT and main themes, the motivation and purpose of the study - the why and how PART TWO is THE REASEARCH - METHODOLOGY and FINDINGS PART ... component in the integration process: The first step towards the integration of refugees must be to identify and help with their most pressing needs Finding and settling them into safe and appropriate ... couples There is a lot of pressure on the couple relationship…Children become more dominant because they learn the language and the mother and the father lose their roles The boundaries and the hierarchies...
Ngày tải lên: 24/02/2014, 18:20
Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf
... (disordered in the ligand-free state in YbgJ) In the absence of the ligand, the lid part is separated from the active site, which leads to a more open active site Upon the binding of ligand in the acyl-enzyme ... conformations of the regions at 100-105 and 303-309 aa in the N form, and we investigated the following points First, these areas are not involved in any contacts with other molecules in crystals in all the ... basis of their crystal structures and the conserved amino acid residues (aa) of their active sites, these glutaminases are classified into a large group of bacterial penicillin-binding proteins and...
Ngày tải lên: 06/03/2014, 09:22
Gentle Measures in the Management and Training of the Young docx
... upon the piazza with blocks and other playthings, and finally had gone into the house, leaving all the things on the floor of the piazza, instead of putting them away in their places, as they ... had been enjoined upon them as, for example, when they left the door open in coming in or going out, in the winter; or interrupted their mother when she was reading, instead of standing quietly ... in accomplishing the result, and in a manner altogether more agreeable to both parties The third will make the work of forming the habit of obedience on the part of the mother, and of acquiring...
Ngày tải lên: 06/03/2014, 20:20
Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt
... shown in Fig 1B, the distance between the two termini of the inserted Ca2+-binding sites in the model structure of the EF-hand of STIM1 is within ˚ 15 A Accordingly, a total of six glycine linkers ... Ca2+-coordinating loop positions and was introduced to perturb the Ca2+-binding ability of the grafted EF-hand of STIM1 (B) Modelled structure of the engineered protein with the grafted EF-hand Ca2+-binding ... EF-hand motif in STIM1 is occupied by Ca2+ Removing the proposed Ca2+-coordinating residues in positions and of the EF-hand motif significantly compromised the metal-binding capability of the engineered...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx
... timescale in both of the free modules Thus, these loops are strong candidates for binding sites of other complement and ⁄ or regulatory proteins The large insertion between E and F strands in C1r ... strands B and C, known as the ‘hypervariable loop‘, D and E, E and F, F and G, and G and H are particularly tolerant of longer insertions [19] In multimodular proteins, however, insertions in the ... of a tyrosine in strand C of CCP4 in place of an asparagine in C1r CCP2 (N379), and based on the results of the present perturbation study, we suggest that the inter-CCP flexibility in C1r is...
Ngày tải lên: 15/03/2014, 23:20
Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt
... ung th in vitro, thấy quercetin làm thoái giáng đột biến p53 - protein, làm ngừng chu kỳ tế bào giai đoạn G1 , ức chế tyrosin - kinase, ngăn chặn hoạt tính protein - ras In vitro, quercetin ức ... Curcumin có nhiều ảnh hởng đến sinh lý bệnh học tế bào ung th: in vitro, curcumin làm ngừng chu kỳ tế bào u, thúc đẩy chết theo chơng trình (apoptosis) Tuy nghiên cứu hạn chế, nhng thấy curcumin ... bào khác nhau, thấy quercetin làm tăng hiệu lực điều trị cisplatin, adriamycin, busulfan, cyclophosphamid làm tế bào ung th giảm đề kháng với gemcitabin topotecan Bromelain Là hỗn hợp protease chứa...
Ngày tải lên: 20/03/2014, 03:20
Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc
... group in the a position of the fatty acyl residues The signals that correspond to the resonance of the methine proton of the a carbon (d) and that of the carbon bearing the methyl group near the ... unknown, and the specific roles of the various members of the DIM family, e.g DIM A and DIM B, in these functions have never been investigated The recent developments in our understanding of the biosynthetic ... obtained for four mice, indicating that fewer than 50 bacteria of the PMM56 mutant strain were present in the spleen of these mice For the determination of the number of PMM56 bacteria present in...
Ngày tải lên: 23/03/2014, 09:20
Báo cáo khoa học: A steady-state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor-1 in the absence and presence of vitronectin ppt
... binding of TM by thrombin Binding of the carboxy-terminal part of the reactive center loop of PAI-1 in the small cleft formed by the 60-loop and VR1 loop can be envisioned The kinetics of the interaction ... PAI-1/VN complexes, suggests the involvement of the chondroitin sulphate of rl-TM in the binding of PAI-1/VN Indeed, both in the absence and presence of PAI-1, the interaction of rl-TM with immobilized ... Pro37 and Gln38 are involved in the binding of TM to thrombin [27,31] These residues therefore comprise the most likely overlapping binding site for TM and PAI-1 on thrombin, as they are also of...
Ngày tải lên: 23/03/2014, 17:21
UPDATES IN THE DIAGNOSIS AND TREATMENT OF VASCULITIS pot
... and prolonged survival of patients with AASV, it has its drawbacks; the worst being life-threat‐ ening infections early in the course of the disease and risk of malignancy in late stages of the ... activation of innate immunity Elevated levels of inflammatory cytokines are usually detectable in the serum and affected tissues in these diseases 15 16 Updates in the Diagnosis and Treatment of Vasculitis ... bind IgA with higher affinity [155] These findings suggest, that TNF-α could be involved in the accumulation of granulocytes and endothelial sequestration of IgA as seen in affected tissues in...
Ngày tải lên: 30/03/2014, 00:20
Updates in the Diagnosis and Treatment of Vasculitis Edited by Lazaros I. Sakkas and Christina Katsiari pptx
... use of the work must explicitly identify the original source Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the ... and prolonged survival of patients with AASV, it has its drawbacks; the worst being life-threat‐ ening infections early in the course of the disease and risk of malignancy in late stages of the ... activation of innate immunity Elevated levels of inflammatory cytokines are usually detectable in the serum and affected tissues in these diseases 15 16 Updates in the Diagnosis and Treatment of Vasculitis...
Ngày tải lên: 30/03/2014, 18:20
Updates in the Understanding and Management of Thyroid Cancer Edited by Thomas J. Fahey doc
... significant change in the incidence of MTC and anaplastic cancer Table shows that the increase in the incidence of PTC was the result of an increased incidence of both MPTC and papillary measuring more ... questions to be in mind; firstly, the increase in thyroid cancer incidence in our area has happened equally in the incidence of MPTC and in the incidence of PTC greater than cm.; secondly, there has ... cancer and fits with the hypothesis of an apparent increase in thyroid cancer incidence Any interpretation of reports of the incidence of papillary thyroid carcinoma must take into account the remarkably...
Ngày tải lên: 30/03/2014, 22:20
believing by faith an essay in the epistemology and ethics of religious belief may 2007
... truth in their practical reasoning will then in uence their action and the decision-theoretic apparatus using the notion of expected utility is a way of making precise the operation of this in uence ... of beliefs dependent on the acceptance of certain framing principles, in the sense that the evidential justifiability of any belief in the framework depends on accepting the truth of those principles ... rejecting belief in omniGod excludes any kind of continuing theistic commitment Yet believers could reject classical theism as an inadequate theory of the nature of God as revealed in the theistic...
Ngày tải lên: 11/06/2014, 05:31
báo cáo hóa học: " Managing variability in the summary and comparison of gait data" pot
... are the aligned curves Note particularly the alignment of the large valley at pre-swing and the peak in swing phase The right column of Figure indicates that the differences in the mean and standard ... for the uncontaminated data Indeed, the actual value of the bootstrap constant initially decreases, likely to counter the accompanying sharp increase in the standard deviation bands In other ... outlier detection and its associated issues altogether, and in the presence of noisy data, which often result from spatio-temporal recordings and parameterizations of kinematic and kinetic curves,...
Ngày tải lên: 19/06/2014, 10:20