Ngày tải lên: 05/09/2013, 09:38
... morphogenic transition. Background Proteolytic processing in vaccinia virus (VV) plays an important role in morphogenic transitions during the virus replication cycle. To date, six VV-encoded, proteolyt- ically processed proteins have ... A10L protein is required for the correct organization of the nucleocomplex within the IVs [7,8]. L4R, a DNA binding protein, plays an essential role in virus replication, being involved in an early ... virus infectivity, but not for core protein process- ing or for INV and EEV formation. Virol 1994, 202:294-304. 10. Wilcock D, Smith GL: Vaccinia virions lacking core protein VP8are deficient in...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " Vaccinia virus A12L protein and its AG/A proteolysis play an important role in viral morphogenic transition" pdf
... protein during VV mor- phogenic transitions and regulation of A12L proteolysis. Conclusion By demonstrating that A12L protein and its cleavage at an N-terminal AG/A play an important role in viral ... fetal calf serum (FCS, Invitrogen), 2 mM glutamine (Invitrogen), and 10 mM gentamicin sul- fate (Invitrogen) at 37°C in a 95% humidified atmos- phere containing 5% CO 2 . For infection of the conditional ... virus infectivity, but not for core protein process- ing or for INV and EEV formation. Virol 1994, 202:294-304. 10. Wilcock D, Smith GL: Vaccinia virions lacking core protein VP8are deficient in...
Ngày tải lên: 20/06/2014, 01:20
Effective Presentations- Dilek Tokay Presentations play an important role in both docx
Ngày tải lên: 28/06/2014, 12:20
Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... polysaccharides, in particular pectin. Two types of arabinogalactan side chains are present in pectin. Type I consists of a chain of b-1,4 linked D -galactopyranose linkages, while type II contains a backbone ... demonstrates the important role of GALA in the degradation of both linear and L -arabinose-substituted galactan side chains of pectin. This is in agreement with a previous study in which the synergy ... The increase in expression levels of galA in the CREA mutant, indicates that at least one of the detected putative CREA binding sites in the promoter of galA is functional. Hydrolysis of arabinogalactans...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx
... mutant ALP I s, two amino acid residues in the C-terminal region were found to play important roles in maintaining stability in highly alkaline conditions. The double muta- tions prolonged the ... of the main chain at Asp266 was bound to amino groups of main chain of Tyr269 and Ala270 by hydrogen bonds. The interactions should maintain the structure of the C-terminal region. In the wild-type ... alkalinity than N263D-Sendai. The mutations at these positions in Sendai should promote instability of the surface region. As the C region of Sendai also would play an important role in restraining...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: NtKTI1, a Kunitz trypsin inhibitor with antifungal activity from Nicotiana tabacum, plays an important role in tobacco’s defense response pot
... obtained from the Internet. A phylogenetic tree was constructed online using the default settings of the web-based alignment tool multa- lin (http://multalin.toulouse.inra.fr/multalin/multalin.html) [59]. Acknowledgements This ... classified into nonspecific and class-specific superfamilies, and the latter was sub- categorized into several families, including serine, cys- teine, aspartic and metalloproteinase inhibitors [11]. Serine ... and Thaumatin-like inhibitors [12]. Kunitz PIs are single-chain polypeptides of around 20 kDa with low cysteine content, generally with four cysteine residues arranged into two intra-chain disul- fide...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo Y học: Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? ppt
... [46]). The sequences of the C-termini of Mnk1 and Mnk2a are similar and contain sequences for MAPK binding. Small differences within these sequences play a role in determining the specificity for ERK ... mammals and insects (at least in Drosophila) – eIF4E is a phosphoprotein. It is phosphor- ylated by the MAP-kinase signal-integrating kinases Mnk1 and Mnk2, at a single site in vivo,Ser209inmammals,which lies ... defect is in cell size rather than cell number. These findings convincingly indicate a role for phosphorylation of eIF4E in cell and organismal physiology. Interestingly, reduction in cell and...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo khoa học: Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis pdf
... sequestering Beclin 1 away from hVps34 [4]. Beclin 1 forms a dimer in solu- tion via its coiled-coil domain both in vivo and in vitro [49]. Viral Bcl-2 binds independently to two sites on the Beclin ... hydrophobic C-terminal mem- brane-spanning domain [58–60]. In contrast, inactive Bax is a cytosolic monomeric protein, because its C-terminal anchor domain is internalized within a hydrophobic ... well-characterized apop- tosis guards, appear to be important factors in autophagy, inhibiting Beclin 1-mediated autophagy by binding to Beclin 1. In addition, Beclin 1, Bcl-2 and Bcl-xL can cooperate with...
Ngày tải lên: 28/03/2014, 23:20
dorsey lopes - important concepts in signal processing, image processing and data compression
... focused on integrating speech recognition and natural language processing to allow spoken language interaction with a naval resource management system. Training air traffic controllers Training ... occurs, including both before and after the recording process as Chapter- 1 Audio Signal Processing Audio signal processing, sometimes referred to as audio processing, is the intentional ... point in the processing a decision is made about which image points or regions of the image are relevant for further processing. Examples are o Selection of a specific set of interest points...
Ngày tải lên: 05/06/2014, 11:40
báo cáo khoa học: " Do mitochondria play a role in remodelling lace plant leaves during programmed cell death?" pps
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: "Pro/con debate: Octreotide has an important role in the treatment of gastrointestinal bleeding of unknown origin" pptx
Ngày tải lên: 12/08/2014, 23:24
Báo cáo y học: "Migration events play significant role in genetic differentiation: A microsatellite-based study on Sikkim settlers" ppt
Ngày tải lên: 14/08/2014, 14:21
Tài liệu A Comparative Analysis of Individual Communication Processes in Small docx
... composition to explain whether individuals exhibit similar or different communication behaviors (i.e., turn-taking and speaking time duration) in small-group decision-making meetings. The findings of the ... cross-cultural communication in examining whether and how individuals communicate differently or similarly in intra- and cross-cultural situations. 14 Proceedings of the 2003 Association for Business Communication ... with people possessing differing levels of English -language proficiency (assuming English is a world business language) . Working in culturally diverse groups differs from working in culturally homogeneous...
Ngày tải lên: 09/12/2013, 16:15
Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... 14.635 lmolặmin )1 ặmg protein )1 . The inset in (A) repre- sents the linear transformation of the curve. (B) Mg 2+ dependency was determined as described in (A) in the presence of increasing concen- trations ... the hydrolysis of inorganic pyrophosphate (PP i ) into inorganic ortho-phosphate (P i ), are widely distributed among living cells. The enzymes play an important role in energy metabolism, providing a thermodynamic ... provide information concerning the kinetics and properties of the enzyme. More strikingly, we show a novel role of the PPase enzyme in the development and molting process of A. suum larvae in vitro. Materials...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Trigger factor interacts with the signal peptide of nascent Tat substrates but does not play a critical role in Tat-mediated export pptx
... Identification of a twin-arginine leader-binding protein. Mol. Microbiol. 40, 323–331. 14. Papish, A.L., Ladne r, C.L. & Turner, R .J. (2003) T he twin- arginine leade r-binding protein, DmsD, interacts ... translocation. TF has been suggested to play a regulatory role in controlling t he entry of secretory proteins in distinct targeting/translocation pathways [ 6,8]. Photo-crosslink ing experiments revealed contacts ... with puromycin or puromycin in a Ôhigh saltÕ buffer after translation but prior to c rosslinking. Both t reatments diminished crosslinking to TF (Fig. 1B, lane 5 a nd 6), indicating that association...
Ngày tải lên: 07/03/2014, 16:20
accounting ethics and its important role for reduction of accounting fraud an empirical study in hanoi
... and misusing insider information. We also know that the accounting fraud lead to diminish the integrity and reliability of accounting and financial information. And accounting fraud originally ... http://hubpages.com http://accountinghelponline.com /role- of-ethics -in- accounting http://www.accountingelite.com/accounting-tips/accounting-fraud-definition-and- examples-free-accounting-fraud-article/ Hiếu ... actions. In fact, conflicts of interest may exist even if there is no harm behavior. In additional, the conflict of interest also contains agency problems and insider trading in business. In real...
Ngày tải lên: 13/03/2014, 14:20
Báo cáo khoa học: Nuclear aggregates of polyamines are supramolecular structures that play a crucial role in genomic DNA protection and conformation potx
... single polyamines, mainly spermine, can modulate the DNA-binding properties of proteins, either increas- ing or diminishing their affinity for DNA [42]. This ability, to modulate the DNA-binding ... rings (i.e. two spermines, two spermidines and two putrescines) linked by phosphate groups (Fig. 3C). We predicted 6-polyamine rings in the structure as (a) 3-polyamine rings are likely to require ... DNA molecules migrating into the gel. We first tested DNA degradation by DNase I upon incubation with increasing concentrations of single polyamines, starting from a concentration of 1 lm polyamines, which...
Ngày tải lên: 23/03/2014, 15:20
Báo cáo khoa học: "Lexical Selection in the Process of Language Generation" ppt
... non-propositional meaning of the input text. The task of a natural language generator is, in some sense, the opposite task of rendering an unambiguous meaning in a natural language. The main task here ... approach differs from this effort in two important repsects. First, in Rubinoff's system the output of TEXT serves as the input to MUMBLE, resulting in a cascaded process. We propose a distributed ... section, focus is an im- portant factor in the generation of discourse anaphors. In this section we demonstrate that focus plays an important role in selecting non-discourse items as well. Suppose...
Ngày tải lên: 24/03/2014, 02:20