james stein estimator as an empirical bayes estimator

Báo cáo y học: " Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays" pot

Báo cáo y học: " Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays" pot

... bias, fk describes the effect associated with these covariates, and ei,k captures the error term, which we assume to be a random normal variable with mean and constant variance Further, we assume ... step and demonstrate important practical implications Across datasets from multiple laboratories and by different methods of validation, CRLMM is just as, and in many cases more, accurate than ... genotype call and calculate a confidence measure for any given pair (sense and antisense) of observed log-ratios: Mi,j,+ and Mi,j,- Notice that these M values can come from any study, and we will...

Ngày tải lên: 14/08/2014, 08:21

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C++ - I/O Streams as an Introduction to Objects and Classes

C++ - I/O Streams as an Introduction to Objects and Classes

... Chapter I/O Streams as an Introduction to Objects and Classes Copyright © 2007 Pearson Education, Inc Publishing as Pearson Addison-Wesley Overview 6.1 Streams and Basic File I/O 6.2 Tools ... data permanently! Data output to a file lasts after the program ends An input file can be used over and over  No typing of data again and again for testing Create a data file or read an output ... Initializing a stream means connecting it to a file The value of the stream variable can be thought of as the file it is connected to Can have its value changed  Changing a stream value means disconnecting...

Ngày tải lên: 12/09/2012, 22:49

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The relationship between default risk and interest rates: An empirical study research insight

The relationship between default risk and interest rates: An empirical study research insight

... period as EDF was computed The classical logistic regression model was specified as following: For additional details on the EDF model and its performance, see Crosbie and Bohn (2004), Dwyer and ... between the changes in 3-month Treasury bill yield, the changes in term structure slope (defined as the difference between 30-year and 3-month Treasury bond yields), and the changes in yield ... find insignificant positive correlations between changes in corporate bond yields (maturity less than or equal to years) and changes in treasury yield slope10y-2y ; and insignificant negative correlations...

Ngày tải lên: 26/10/2012, 11:21

17 737 0
USING BRAND AS AN EFFECTIVE WEAPON TO COMPETE IN THE MARKET: A CASE STUDY OF NHAT LINH COMPANY

USING BRAND AS AN EFFECTIVE WEAPON TO COMPETE IN THE MARKET: A CASE STUDY OF NHAT LINH COMPANY

... the brand -as- product, brand -as- organization, brand -as- person, and brand -as- symbol • Brand identity structure includes a core, extended and proposition identity A brand identity is to brand strategy ... offer quality assurance and reduce risks • Brands help self-expression • Brands offer friendship and pleasure 2.3.2 A brand is more than a product Brand is more than a product Branding is about ... Company with the assistance of his young brother, the Company’s Vice Director When asking about the soul and other attributes of LiOA brand name such as brand identity, brand personality and brand...

Ngày tải lên: 13/04/2013, 10:29

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THE INFORMAL SECTOR IN SOLID WASTE MANAGEMENT IN DEVELOPING COUNTRIES SUSTAINABILITY EFFECTS OF FORMALISATION CONSIDERING HO CHI MINH CITY – VIETNAM AS AN EXAMPLE

THE INFORMAL SECTOR IN SOLID WASTE MANAGEMENT IN DEVELOPING COUNTRIES SUSTAINABILITY EFFECTS OF FORMALISATION CONSIDERING HO CHI MINH CITY – VIETNAM AS AN EXAMPLE

... by the value of the waste, and in the second place by their ease of extraction, handling and transport Paper, metals and plastics, sorted out as early as possible in the waste chain, therefore ... I.1 Background Human activity has always created and will always create waste In big cities around the world Solid Waste Management (SWM) is an especially important and complex task for the municipalities ... collection, transport, transfer, processing and disposal of solid wastes The growing demand for service caused by rapid, unplanned urban growth and rising waste generation rates can often only...

Ngày tải lên: 24/08/2013, 18:48

112 594 5
The phenomenon of evaporative cooling from a humid surface as an alternative method for air-conditioning

The phenomenon of evaporative cooling from a humid surface as an alternative method for air-conditioning

... economic solution than installing an only system In 1986, Anderson tested an air conditioning system using a direct and an indirect evaporative cooler combined with an expansion battery, and compared ... material, another device mainly made of wet textile band has been designed, manufactured and characterised It is basically a cotton band of 25 cm width and 1600 cm length, disposed in a plasticized ... developed by the ASHRAE has cast doubt on this supposing, making more interesting the idea of considering and analyzing the use of these devices Another disadvantage is the water consumption associated...

Ngày tải lên: 05/09/2013, 16:10

28 653 0
ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

... Finance , 60, 11291166 Hovakimian, A., Opler, T., and Titman, S (2001) The debt-equity choice Journal of Financial and quantitive analysis, 36, 1-24 Huang, G., & Song, F (2006) The determinants ... 75-109 Lang, Ofek and Stulz RM Leverage, investment and firm growth J Finance Econ 1996; vol 40, p 3-29 Leland, Hayne and David Pyle, 1977, Information asymmetrics, financial structure, and financial ... leverage and fixed assets in small and medium firms (Daskalakis and Psillaki, 2009) and in less developed economies (Joever, 2006) The proxy used in this study to measure the value of tangible assets...

Ngày tải lên: 09/09/2013, 23:46

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ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

... (2012), An Annual report is a report created annually that provides an analysis and assessment of the trends of the past year An annual report can help one to understand the strengths and weaknesses ... bank boards and bank performance (measure by Tobin’s Q) at 10% significant level Board size (logTotalAsset) and Leverage (Debt/Total assets ratio) was negative and significant at 1% significant ... financial performance To measure firm financial performance, accounting-based and market-based calculations are used And date will be gotten from annual report of bank 2.5.1 Financial performance The...

Ngày tải lên: 09/09/2013, 23:50

51 547 0
Evaluation of employees’ job satisfaction and role of gender difference   an empirical study at airline industry in iran

Evaluation of employees’ job satisfaction and role of gender difference an empirical study at airline industry in iran

... Behavior and Management Boston: Kent Publishing Company Locke, E A (1968) Toward a theory of task motivation and incentives Organizational behavior and human performance, 3(2), 157-189 Luthans, F ... employees were asked to participate in the survey and the questionnaires were handed over to them manually and by Email Questionnaire formally classified as standard instrument for measuring employees‟ ... mean value from 1-2.33 as low satisfaction, mean value between 2.34 -3.67 as medium level of satisfaction and the means over 3.67 as high satisfaction Table shows the result of descriptive analysis...

Ngày tải lên: 11/09/2013, 11:44

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Tài liệu Understanding the Internet as an Infrastructure docx

Tài liệu Understanding the Internet as an Infrastructure docx

... but are rendered as HTML to allow them to operate correctly in any HTML-compliant browser Microsoft has also extended many of the standard HTML controls as well, allowing you to manipulate them ... optimize throughput and Web site maintainability Microsoft has also added the following features: • Enhanced page design and layout using Master Pages, Themes, and Web Parts You can use Master Pages ... things, such as display a page of data from a database; mixing application code and HTML caused readability and maintenance issues; and performance was not always what it could be because Active Server...

Ngày tải lên: 15/12/2013, 00:15

4 355 0
Tài liệu Impact of Government Policies and Investment Agreements on FDI Inflows to Developing Countries: An Empirical Evidence doc

Tài liệu Impact of Government Policies and Investment Agreements on FDI Inflows to Developing Countries: An Empirical Evidence doc

... FDI inflows and found them to be important determinants in the 1990s decade [e.g., Gastanaga, Nugent and Pashmova (1998), Taylor (2000), Chakrabarti (2001) and Asiedu (2002)] Globerman and Shapiro ... inflows between Asia and Pacific is biased heavily towards the Asian countries The average annual inflow into Asian countries in the 1980s was around 97 per cent, this further increased to around ... principles (NBIP) and investment area agreement (AIA) reached by Association of Southeast Asian Nations (ASEAN) These are captured by a dummy variable for the country’s membership of ASEAN and APEC We...

Ngày tải lên: 17/12/2013, 05:15

41 510 1
Tài liệu 27 Robust Speech Processing as an Inverse Problem docx

Tài liệu 27 Robust Speech Processing as an Inverse Problem docx

... cepstral mean subtraction (CMS) [6] If the mismatch is caused by both channel and random noise, the testing vector is translated as well as shrunk The shrinkage is measured by αjj and the translation ... operator, and V AR[] and COV [] represent the variance and covariance operators, respectively As can be seen from Eq (27.60), the diagonal entries αjj are the weighted covariance of the model and the ... channel and (b) Gaussian white noise the key to the problem is to find feature sets that are invariant1 to the changes of transmission channel and environmental noise Liftered cepstrum [9] and...

Ngày tải lên: 25/12/2013, 06:16

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Tài liệu Module 13: Using Excel as an OLAP Client docx

Tài liệu Module 13: Using Excel as an OLAP Client docx

... at least one measure to the Data Items area—a PivotTable must have at least one data item You can place more than one dimension in the page, row, and column regions You can pivot page, row, and ... capabilities that enhance the ability to manage the data and organization of a PivotTable report The following are additional capabilities that enhance the ability to manage the data and organization of ... reproduced or transmitted in any form or by any means, electronic or mechanical, for any purpose, without the express written permission of Microsoft Corporation If, however, your only means of access...

Ngày tải lên: 18/01/2014, 05:20

38 319 0
Tài liệu Configuring Linux as an NIS Client ppt

Tài liệu Configuring Linux as an NIS Client ppt

... be the easiest way Step At this point, the Linux system should be setup to run as an NIS client If this system was connecting to an actual NIS server, the ypwhich and ypcat hosts commands could ... be erased unless the system is configured to run this command every time the system boots up There are many methods that can be used to force a Linux system to run commands upon startup Many of ... The ypbind daemon performs two functions, the master and the slave functions The master process handles requests for information from the NIS server and the slave process checks the bindings - IT...

Ngày tải lên: 18/01/2014, 05:20

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Tài liệu FOCUS ON DATA XMLPULL AS AN ALTERNATIVE TO DOM & SAX doc

Tài liệu FOCUS ON DATA XMLPULL AS AN ALTERNATIVE TO DOM & SAX doc

... occupy more than one code unit—it can be multi-byte) All three encodings can display any Unicode character, and each has its own advantages and disadvantages depending on what’s important in a particular ... New Roman, and Courier New—are Unicode compliant However, that doesn’t mean they can display any Unicode character They are fine for English and most Central and Eastern European languages For ... session cannot exist without an underlying request As a result, it seems natural to conclude that our static HTTPRequest class should yield, on demand, an instance of an HTTPSession class by means...

Ngày tải lên: 24/01/2014, 14:20

63 497 1
Tài liệu Báo cáo khoa học: Multi-targeted activity of maslinic acid as an antimalarial natural compound pdf

Tài liệu Báo cáo khoa học: Multi-targeted activity of maslinic acid as an antimalarial natural compound pdf

... [12,31] To ascertain the inhibition range of MA on the different P falciparum protease classes, in vitro enzymatic assays were performed encompassing cysteine, aspartic, serine and metalloproteases ... the aspartic protease catalytic class, was previously reported [12] Accordingly, an additional inhibition assay was performed using P falciparum protein extracts and including cathepsin D (an aspartic ... reported antioxidant [4,5], vasorelaxation [6] and anti-tumoural [7,8] activities, MA has been shown to specifically inhibit glycogen phosphorylase [9,10] and protein tyrosine phosphatase 1B [11],...

Ngày tải lên: 14/02/2014, 14:20

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Tài liệu Cancer as an evolutionary and ecological process pptx

Tài liệu Cancer as an evolutionary and ecological process pptx

... Conclusions and future directions To understand cancer, we need to understand and measure the population dynamics and evolutionary parameters of neoplasms These measurements provide biomarkers that can ... (Sinauer Associates Inc., Sunderland, Massachusetts, 1998) 91 Paszek, M J et al Tensional homeostasis and the malignant phenotype Cancer Cell 8, 241–254 (2005) 92 Vaupel, P & Mayer, A Hypoxia and anemia: ... between organs There is some evidence that polyploidy in plants, and perhaps aneuploidy in neoplasms, is associated with an ability to invade new environments98, perhaps owing to an increased opportunity...

Ngày tải lên: 15/02/2014, 05:20

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Tài liệu An Empirical Decomposition of Risk and Liquidity in Nominal and Inflation- Indexed Government Bonds pptx

Tài liệu An Empirical Decomposition of Risk and Liquidity in Nominal and Inflation- Indexed Government Bonds pptx

... the crisis financing a long position in TIPS was about 40 basis more expensive than financing a long position in nominal Treasury bonds, but this cost differential rose to more than 120 basis points ... the demand for nominal and real bonds 25 References Acharya, Viral V., and Lasse Heje Pedersen, 2005, "Asset Pricing with Liquidity Risk", Journal of Finance, 77:375—410 Anderson, Nicola and John ... Forward Rates”, American Economic Review 77, 680-692 Fleckenstein, Matthias, Francis A Longstaff, and Hanno Lustig, 2010, "Why does the Treasury Issue TIPS? The TIPS-Treasury Bond Puzzle", NBER...

Ngày tải lên: 16/02/2014, 02:20

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