integrative therapies in chronic pulmonary conditions

... G, Guérin C: Six-month outcome in acute kidney injury requiring renal replacement therapy in the ICU: a multicentre prospective study Intensive Care Med 2009, in press Whitcomb DC: Clinical practice: ... patient group in particular may benefit from a structured rehabilitation programme continuing after hospital discharge Competing interests The authors declare that they have no competing interests ... a multicentre observational study examining the relationship between the amount of energy and protein administered during ICU stay and clinical outcomes in critically ill patients, and the extent...

Ngày tải lên: 13/08/2014, 19:20

... as the followings: 50-80% - appropriate; > 80 inappropriate; < 50% - inappropriate [1, 2, 3] Wind speed: Wind spreads radiate heat on the surface of human skin In the hot season, wind makes the ... m/s - inappropriate Rainfall: Rainfall affects directly on tourism activities such as swimming, surfing, water-skiing, sailboat, airdrop or parachute jump sports Sometime heavy rain (daily rainfall ... the term “Highland” is known as mountainous regions in Vietnam, including mountainous regions in the North and Central highland The term “Lowland” is defined as deltas, hilly areas and coastal...

Ngày tải lên: 14/03/2014, 15:20

... thư vú - adenoca, lymphoma): chữa Cytoxan, Vincristine, Prednisone Rituximab Hè 2006 bà than ngứa, nghi lymphoma trở lại , CAT scan PET's xác nhận clinical impression - bà bị rheumatoid arthritis ... function tests) thấy bilirubin tăng : 2.1 CAT scan cuả bụng negative, thế, giải thích Bilirubin tăng (bệnh nhân Gilbert's syndrome), gửi sang gastroenterologist xin làm ERCP tức (Endoscopic Retrograde ... melanoma, and non-melanoma; phải đối diện với biến chứng non-malignant: thí dụ pulmonary fibrosis (biết rõ truờng hợp dùng bleomycin chẳng hạn testicular cancer) (hoặc hồi xưa: CHOP-Bleo) cardiovasc,...

Ngày tải lên: 13/07/2014, 22:20

... baseline (Baseline Dyspnea Index) in order to answer questions regarding the TDI [28] Therefore, we used the MMRC scale which is a traditional instrument included in the BODE index [20] In multiple ... weight in kg/(height in m)2] was calculated Smoking history was obtained by patient interview using standardized instruments at baseline and smoking cessation by self report during patients’ contacts ... follow-up This finding reinforces the impact of exacerbation in clinical outcomes; exacerbations of COPD indicate clinical instability and progression of the disease and are associated with increased...

Ngày tải lên: 11/08/2014, 23:22

... study conducted in a Veterans Administration (VA) hospital A previous publication described how the original data was obtained [17] First, investigators identified patients with any inpatient or ... is self-administered and includes 50 items in three components: symptoms, activity, and impact on daily life [21] The SGRQ scores range from to 100, with indicating no impairment in the quality ... comorbid conditions that might have been captured by the generic measure had a role in this finding This study had some limitations The sample size used in our analyses may have yielded insufficient...

Ngày tải lên: 12/08/2014, 01:22

... in healthy individuals [18,19] In COPD, the abdominal muscles are frequently recruited even during resting breathing [20] When walking to exhaustion, inspiratory work of breathing in COPD rises ... case in normal subjects, in whom the distinction into inspiratory and expiratory is not absolute During exercise, at least in normal subjects, the expiratory muscles act as accessory muscles of inspiration ... exercise in subjects cycling having first undergone an expiratory muscle fatiguing protocol, than following an equivalent exercise duration when not first fatigued [36] Interestingly, in that...

Ngày tải lên: 12/08/2014, 11:20

... concentrations of pro-inflammatory cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-8 (IL-8), and tumour necrosis factor-alpha (TNFalpha) were measured using quantitative ... Jansen HM, Lutter R: Persisting Haemophilus influenzae strains induce lower levels of interleukin-6 and interleukin-8 in H292 lung epithelial cells than nonpersisting strains Eur Respir J 1997, 10:2319-2326 ... Schering Pharma We thank Marta Pulido, MD, for providing an outline for this manuscript and support in editing and journal styling Bayer Schering Pharma was the source of funding for medical writing...

Ngày tải lên: 12/08/2014, 11:21

... COPD stages [10] In contrast, an inverse association between higher levels of circulating inflammation-sensitive proteins, including CRP, interleukin (IL)-6 and alpha-1 antitrypsin (A1AT), and ... walked in minutes (m) Distance walked in minutes (m) 1000 800 600 400 200 0 r=-0.137 p = 0.019 800 600 400 200 log CRP 1000 r=-0.174 p = 0.003 Distance walked in minutes (m) Distance walked in minutes ... ageing rate and longevity FEBS Lett 2005, 579:2035-2039 Ben-Zaken Cohen S, Paré PD, Man SFP, Sin DD: The growing burden of chronic obstructive pulmonary disease and lung cancer in women Examining...

Ngày tải lên: 12/08/2014, 11:22

... to inhaled corticosteroids prior to screening † Data missing for four patients in ACCLAIM/COPD I (two each in the aclidinium and placebo arms) BMI: body mass index; COPD: chronic obstructive pulmonary ... Garcia GE, Ferrer P: Safety and pharmacokinetics of single doses of aclidinium bromide, a novel long-acting, inhaled antimuscarinic, in healthy subjects Int J Clin Pharmacol Ther 2009, 47:460-468 Chanez ... approved the final version prior to submission Competing interests PWJ has received fees from a number of pharmaceutical companies, including Almirall, for speaking at meetings and for consulting and...

Ngày tải lên: 12/08/2014, 13:22

... immunohistochemical staining G), Hematoxylin and Eosin (HE) staining; H), Single staining for a-SMA; I), Single staining for CD31; J), Double staining for CD31 and a-SMA; the magnification was 200× ... staining was DAPI G-J), Immunohistochemical staining of endarterectomized tissue The neointimal layer of distal vascular wall tissues was assessed by immunohistochemical staining G), Hematoxylin ... standard hematoxylin and eosin (H & E) staining was performed The CD31 antibody was used to stain endarterectomized tissue, together with aSMA to stain transitional cells aSMA staining (blue) was...

Ngày tải lên: 12/08/2014, 14:20

... 30-minute periods of cycling exercises, walking, and inspiratory muscle training each The cycling protocol consisted of intervals of one minute loaded cycling (aimed at 140% of a patient’s initial ... and one minute unloaded cycling, during 30 minutes [14] Inspiratory muscle training was performed on an inspiratory threshold device at an interval basis (two minutes of loaded breathing, followed ... group) Oxygen was used during training to maintain arterial oxygen saturation >90% NIPPV In the NIPPV + PR group, patients were instituted on nocturnal bilevel NIPPV Noninvasive ventilation was...

Ngày tải lên: 12/08/2014, 14:20

... Longitudinal average Wheezing Baseline Longitudinal average Nighttime Symptom Scores Difficulty breathing Baseline Longitudinal average Coughing Baseline Longitudinal average Wheezing Baseline Longitudinal ... was encouraging and in keeping with the findings reported in the larger series of BMD measurements made in US participants in the TORCH study [26] As in that report and in the INSPIRE study http://respiratory-research.com/content/9/1/73 ... greater in ex-smokers (those who quit smoking ≥ 10 months before baseline) than in those who continued smoking Mean changes in cigarette use during treatment were low (< cigarettes/day) in all...

Ngày tải lên: 12/08/2014, 14:20

... difference in the results obtained In addition it was possible in most patients to correlate their reports of exacerbations with the medical notes relating to clinic attendances in the intervening year ... exacerbators Decline in QMVC in this cohort was not associated with disease severity, having frequent exacerbations or corticosteroid treatment Change in fat free mass during follow up Decline in FFM was ... follow up, decline in fat free mass was independently associated with more marked gas trapping, a higher FFM at baseline and use of maintenance oral corticosteroids, whereas FFM increased in patients...

Ngày tải lên: 12/08/2014, 15:20

... staining in the both alveolar wall and alveolar Figure Lung sections stained for elastin, versican and elastin binding protein Lung sections stained for elastin, versican and elastin binding ... Figure Relationship between elastin binding protein and elastin Relationship between elastin binding protein and elastin Relationship between EBP immuno-staining intensities for alveolar wall (a) ... elastin receptor: a galactosidase-binding protein Science 1988, 239:1539-1541 Mecham RP, Whitehouse L, Hay M, Hinek A, Sheetz MP: Ligand affinity of the 67-kDa elastin/laminin binding protein is...

Ngày tải lên: 12/08/2014, 15:21

... containing 1% penicillin, 1% streptomycin, and 1% gentamycin at 37°C in 5% carbon dioxide/air for 16 hours Tissue was then either stimulated with 100 ng/ml LPS (Sigma-Aldrich, UK) or maintained in ... cytokines most reportedly elevated in COPD patients during exacerbations Figure of Severity COPD influences cytokine release Severity of COPD influences cytokine release Using the GOLD guidelines ... the accumulating evidence of extra pulmonary manifestations in COPD including cachexia and systemic inflammation which are observed in severe COPD patients In our model of acute inflammation...

Ngày tải lên: 12/08/2014, 15:21

... changes include an increase in mitochondrial number, increased muscle capillarization, and an increase in muscle oxidative enzyme activity After intense training the proportion of type I fibers increases, ... alone is not usually successful in increasing lean body mass in patients with COPD In one study [67] an increase in the creatine phosphate/ creatine phosphate + creatine ratio (measured from quadriceps ... [18] In one study [16], phosphofructokinase (a glycolytic enzyme that is involved in anaerobic metabolism) was significantly increased in patients with COPD, but this finding was not confirmed in...

Ngày tải lên: 12/08/2014, 18:20

... airways), which may be insufficient to obtain a full view Fourth, remodelling in COPD may itself generate and maintain an inflammatory process, independent of cigarette smoking [25] In order to elucidate ... underlying macrophage infiltration, which is part of the ongoing inflammatory process in COPD This is important to realise when investigating the inflammatory and remodelling processes in smokers and ... obstruction in COPD, suggesting that cumulative smoking induces chronic inflammation with subsequent sequelae of airway obstruction Our results indicate that inflammatory effects of current smoking may...

Ngày tải lên: 12/08/2014, 18:21

... in particular no significant effect on arterial blood gases The rationale behind this study was based on the findings that angiotensin converting enzyme and angiotensin II are both involved in ... Studies of pulmonary hypertension I Pulmonary circulatory dynamics in patients with pulmonary emphysema at rest J Clin Invest 1953, 32(2):130-7 Heath D: Remodeling of the pulmonary vasculature in hypoxic ... Danilov SM, Stenmark KR: Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension J Clin Invest 1995, 96(4):1823-33 Kiely...

Ngày tải lên: 12/08/2014, 18:22

... to maintain a constant Pappl, a change in any one of its determinants (Pmus or Paw) must be met by an opposite change in the other In clinical terms, this means that, for instance, increasing ... MV including NIV, and to a shorter ICU stay compared to standard physician-driven weaning [32] Cycling In PS mode, the transition from inspiration to expiration, known as cycling, occurs when instantaneous ... Consequences of delayed cycling PEEPi, intrinsic positive end-expiratory pressure Figure Mathematical modeling of the inspiratory instantaneous flow-time curve for progressively increasing levels of airway...

Ngày tải lên: 13/08/2014, 03:20

... monitored in an intensive care unit setting and, if there is no improvement in gas exchange or vital signs within the first to hours, intubation should be planned with no delay in the best conditions ... combined with FBO in COPD with hypercapnic encephalopathy) in the most challenging patients Abbreviations COPD, chronic obstructive pulmonary disease; FBO, fibreoptic bronchoscopy; NPPV, noninvasive ... 2007, 11:210 Evans TW: International Consensus Conferences in Intensive Care Medicine: non-invasive positive pressure ventilation in acute respiratory failure Organised jointly by the American...

Ngày tải lên: 13/08/2014, 20:22