... hand, and on the other by the attitude ofthe speaker towards the message and the addressee "Thus into the domain ofthe organization of utterance pertains all that is connected with the processual ... basic hypotheses, the second of which can conveniently be elaborated in terms of Ong's list ofthe characteristics of an orally-based language The two hypotheses and their respective sub-hypotheses ... aspect of utterance (in contrast to the abstract and static character ofthe other two levels), that is to say, the dynamism ofthe relations between the meanings of individual lexical items in the...
... vitro In these authors’ opinions, such studies obviously represent the next logical step in the unfolding story ofthe modulation ofthe oligomeric structuresof HIV-1 viral enzymes by synthetic ... aminoacid residues at the N- and C-termini of PR contribute close to 75% ofthe total Gibbs energy [15] The importance of this four-stranded b sheet is further emphasized by the fact that all PR ... plasmid (that contains the selection module kPR-lacZ-tet and directs the production ofthe cI-PR fusion protein), cI-PR represses the transcription ofthe reporter genes and the transformants show...
... critical They include the outcome of various studies that the authors have been involved with over a number of years with a variety of partners They also include a study ofthe works of a number of ... means the downfall ofthe corporation you work for Don’t believe us? The printing press nearly killed off one ofthe largest corporations in history – the Catholic Church At the start ofthe sixteenth ... live and work In fact, they are revolutionizing it The outcome of this fact is that the balance of power in the business world is shifting In very short order, the theory ofthe firm is going to...
... suggesting the intimate link between the sugar metabolic pathway and osmolytic homeostasis 1.9 Fate of synthesized sucrose The rate of sucrose synthesis increases with the rate of photosynthesis ... and Ribose (white) (a) Stereo diagram of HoFRK (cyan) and the complex structuresofthe three ribokinase family members, superimposed on the HoFRK model at the catalytic domain 93 2.18 2.19 2.20 ... times of stress 1.7 Sucrose synthesis Most ofthe carbon needed for the production of sucrose originate from triosephosphate molecules produced by the light-independent pathway of photosynthesis,...
... 24 Plots ofthe top 20 regions ofthe varRecM scores for the comparison between samples of HapMap CEU and JPT+CHB 164 Figure 25 Plots ofthe top 20 regions ofthe varRecM scores for the comparison ... regions ofthe varRecM scores for the comparison between samples of SGVP CHS and INS 170 Figure 28 Plots ofthe top 20 regions ofthe varRecM scores for the comparison between samples of SGVP ... with the breakdown of linkage disequilibrium (LD) observed across the population samples based on population coalescent theory101 The resolution of these maps thus depends on the density of the...
... patients), the proportion of MET calls which reflects deficiencies in care may be even higher The present study introduced the novel element of real-time characterization of events by the team at the ... substantial investments of additional resources Moreover, the direct involvement of clinicians in the detection of patient safety and quality -of- care problems likely facilitates the crucial next step ... debriefing flows naturally from the chart review that MET personnel perform to the providing of patient care This methodology does not replace the need for other forms of adverse event detection (such...
... antimicrobial therapy in case of unexpected infiltrates on the CXR; repositioning of tubes in case of malposition of orotracheal tubes (ignoring planned extubations); ultrasound ofthe thorax in case of ... as removal of intravenous lines) The observers were not involved in the daily care ofthe patients, and ICU physicians were not aware of this part ofthe observation As a consequence, the clinical ... look for other infections, and the absence of radiological signs of pulmonary congestion might have resulted in another fluid therapy regimen We did not score for the clinical relevance ofthe unexpected...
... kind of audience? What 27 – THE A Z OFMEDICAL WRITING format? Is there an example ofthe kind of conference report they like (and perhaps one they don’t)? • At the conference, just soak up the ... before – THE A Z OFMEDICAL WRITING the article is written (see brief setting) This should limit the practice of people jumping aboard once all the work has been done The real cause ofthe trouble ... they are there Some of us cannot resist the challenge; but it’s hardly rational behaviour Books, writing of chapters in One ofthe great advantages of multi-authored books is that they meet the...
... questions (if/ whether ) Notes: S + asked ( O) Wanted to know + If/ whether + Wondered S+V Change in adverbs and articles this these here now tomorrow today → that → those → there → then → the following ... store the following day Question: - “what is your name?” the teacher asked me = >The teacher asked (me)what my name was Note: She said, “Are you thirsty, Mary?” She asked Mary if (whether) she ... Compare: (hai vật ngày phát triển song song) Form: Short adj: The adj +er + S+ V, The adj +er + S+ V Long adj: The more +adj + S+ V, The more +adj + S+ V 32 V + preposition be amazed at / be amused...
... cause of offence In these habits we resemble the Aborigines of our country They load their huge pipes with the dried leaves of this plant, and when lighted, they breathe the dark cloud of smoke ... condition ofthe vessels belonging to the membranes ofthe socket, with the condition of which, the state ofthe tooth is closely connected."] Having gone through with an examination ofthe physical ... it capable of giving strength to the weary, vivacity to the stupid, and wisdom to men void of understanding; capable of soothing the sorrows ofthe afflicted, of healing the wounds ofthe spirit,...
... tumour ofthe eye, a remarkable swelling ofthe upper lip, and painful tumours ofthe joints ofthe fingers, much relieved; but the medicine was left off, on account of its violent effects on the ... predilection in favour ofthe medicine: but I cannot advise them to this step, for I am certain they would then close the book, with much higher notions ofthe efficacy ofthe plant than what they would ... afforded me, in perfecting some ofthe cases, and in communicating the events of others The ages ofthe patients are not always exact, nor would the labour of making them so have been repaid by any...
... ofthe structure are not seen on the map, probably owing to disorder of these regions The overall geometry ofthe model according to the procheck program [21] is of good quality, with 95.4% of ... to elucidate the mechanism ofthe elevated thermostability of TtAKb In this article, we describe the crystal structuresof TtAKb in two forms, Thr-bound and Thr-free, and discuss the regulatory ... regulatory mechanism of Thr and the structural features responsible for the high thermostability of TtAKb Results and Discussion Model quality The crystal structure ofthe Thr-bound form of TtAKb ˚ (TtAKb-Thr)...
... tumour ofthe eye, a remarkable swelling ofthe upper lip, and painful tumours ofthe joints ofthe fingers, much relieved; but the medicine was left off, on account of its violent effects on the ... predilection in favour ofthe medicine: but I cannot advise them to this step, for I am certain they would then close the book, with much higher notions ofthe efficacy ofthe plant than what they would ... afforded me, in perfecting some ofthe cases, and in communicating the events of others The ages ofthe patients are not always exact, nor would the labour of making them so have been repaid by any...
... determinant As the C3a ion is at m/z 690, this excludes the possibility ofthe other Fuc being at the Gal next to the subterminal GlcNAc The position ofthe second Fuc 3-linked to the internal ... analysis ofthe branching patterns and blood group determinants with low (picomole) amounts ofthe underivatized oligosaccharides The significant aspects of this strategy are the combined use of CID ... downfield from the Fuc IX H5 proton For TFiLNO, the same temperature would have resulted in total overlap ofthe H2O signal with the Fuc X and XI H5 protons Therefore the temperature of 27 °C was...
... for the understanding ofthe genetics of this significant food-borne pathogen We therefore elucidated thestructuresof these major cell surface carbohydrates to make functional analysis ofthe ... placed the sole a-D-Gal sidebranch at O-2 ofthe unit with the anomeric at d 4.99, which has to belong to the sole 2-substituted unit, that being the 2,3-disubstituted Gal in the backbone The other ... observation in the linkage analysis that the 6-O-Me-Hep was a terminal unit The fragment ion at 382 arose from the loss of both the 6-O-Me-Hep and GalNAc, which then lead to the loss of Rib with...
... form ofthe enzyme runs along the axis ofthe b-propeller through the whole domain and is only blocked by Cys236 in the area ofthe subsite )1 binding the fructose molecule A number ofstructures ... inside of it, which resembles the shape of a fishtrap The active site is located at the bottom ofthe axial funnel created by the interblade loops and the loops between b-strand 2–3 of each blade The ... results of MS of recombinant b-fructofuranosidase are close to the theoretical value ofthe molecular mass A peak of molecular ion at m ⁄ z = 58 879 Da was observed on the MALDITOF mass spectrum The...
... about to create In short, the concept ofthe physician as a professional in the intellectual and moral senses ofthe term and therefore the concept ofthe profession of medicine in its intellectual ... History of Medicine, the University of Michigan, the University of Pittsburgh, the Cleveland Clinic, the New York Consortium for the History of Medicine at the New York Academy of Medicine, and the ... before him there was no professional medical ethics worthy ofthe name in the English language; after him there was The history of English-language medical ethics and therefore history of medicine,...
... employed and the presentation ofthe material in this publication not imply the expression of any opinion whatsoever on the part ofthe World Health Organization concerning the legal status of any ... manifestations of pain Young children usually use the simple words that they learn from their parents to express pain (such as “ouch”) and may point to the part of their body in which they feel the pain The ... display none ofthe expected cues They may deny their pain for fear of more painful treatment, for example, they may be fearful of injections Absence of these signs does not mean absence of pain and...
... sequenced Of these, 10 clones were found to encode the LC2 and LC1 subunits Others were found to encode other variants ofthe C-lectin-like venom proteins The amino acid sequences of both subunits ... HC, the light chains appear to confer the substrate specificities of RVV-X [12] Collectively, the primary sequences ofthe three subunits of RVV-X (Figs and 5) suggest the possible presence of ... systemic haemorrhage in mice These results emphasize the importance ofthe rapid homing of RVV-X into microvessels to exert its effect The glycan structuresof a number of venom glycoproteins have...
... PDmut On the other hand, stacking at the AC(6–7) step in the DNA strand of PDwt is retained during the entire simulation in spite ofthe large movement of C7 (Fig 2A) This occurs due to the coordinated ... efficacy ofthe designed PNA to down-regulate the gene expression ofthe mutated allelle, while sustaining the transcription ofthe wild-type allele [29,29a] The present investigation is the first ... also text) despite the fluctuations Complete loss of stacking interaction is seldom seen (A) ofthe amino group of C7 with A6 (Fig 4B) or through the overlap ofthe six-member ring of C7 with A6 (Fig...