in vitro release from lipophilic solutions
in vitro release of ketoprofen from proprietary and extemporaneously manufactured gels
Ngày tải lên :
13/04/2014, 09:25
... entering the skin which include irreversible binding to cutaneous proteins such as keratin, degradation by cutaneous enzymes and partition into subcutaneous fat (36, 39) Many in vitro and in vivo ... molecules, both in vitro and in vivo These methods include in vitro and in vivo delivery of insulin, mannitol, glucose and heparin (17, 80) Phonophoresis may have an additional advantage in the transcutaneous ... may increase skin/vehicle partitioning of the drug and they may increase solvent transport into or across the skin The results of increased penetration may include increased drug solubility in...
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Báo cáo khoa học: Modulation of nitric oxide-mediated metal release from metallothionein by the redox state of glutathione in vitro doc
Ngày tải lên :
07/03/2014, 15:20
... compound(s) being involved in this interaction in living cells and information about this additional factor is needed in order to perform physiologically relevant future in vitro studies and in the interpretation ... binding of NO to GSH in vivo does not obviously prevent NO from interacting with MT2, we have shown that in vitro it suppresses the metal release from metallothioneins This points to an hitherto ... obtained from in vivo experiments on the NO–MT interaction As predicted earlier [31], zinc is more readily released from MTs than cadmium, which is probably a combination of tighter binding of...
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Báo cáo khoa học: Choline increases serum insulin in rat when injected intraperitoneally and augments basal and stimulated aceylcholine release from the rat minced pancreas in vitro pptx
Ngày tải lên :
17/03/2014, 09:20
... on insulin release from minced pancreas To determine if choline elicits insulin release in vitro, minced pancreas was incubated with various concentrations of choline The rate of insulin release ... acetylcholine levels in the pancreas Effect of HC-3 on choline-induced increases in acetylcholine release from the minced pancreas To determine whether choline-induced increases in acetylcholine release are ... blocked the choline-induced increase in insulin (Table 1) Effects of relatively selective antagonists of muscarinic receptors on choline-induced increases in serum insulin To determine the involvement...
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Báo cáo y học: "Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro" ppt
Ngày tải lên :
09/08/2014, 10:22
... following traumatic injury The inhibition by COX inhibitors of PGE2 release following trauma may provide an opportunity for early clinical intervention to reduce cell death from apoptosis Our in vitro ... incorporation of proline into collagenase digestible proteins in human articular chondrocytes: identification of an effector autocrine loop involving insulin-like growth factor I Mol Cell Endocrinol 1996, ... hyaluronic acid in samples of OA cartilage in vitro Non-selective NSAIDs have differing effects on cartilage metabolism Some stimulate, some have no effect, and others – including indomethacin – inhibit...
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In vitro drug release mechanism from cholesteryl ester composed liquid crystalline system
Ngày tải lên :
09/10/2015, 11:18
... diffusion NT Cinnarizine duodenal NT Kossena et al 2004 In vitro Zeroorder; first-order Burrows et al 1994 Cubic Atenolol Melatonin Pindolol Propranolol Pyrimethamine Insulin In vitro NT Sadhale ... administration of cinnarizine loaded into performed cubic phase comprising a monolaurin / lauric acid mixture, resulted in a slow release in the concentration of cinnarizine in plasma compared ... melting point or the transition point, while the temperature at which the true liquid is obtained has been referred to as the clarification point, clearing point, transition point, or melting point...
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Phosphate removal from aqueous solutions using red mud wasted in bauxite Bayer's process
Ngày tải lên :
23/09/2012, 14:47
... removal of phosphates from aqueous solutions [7] Zakharova et al have reported the production of mixed aluminium-iron coagulant from red mud and spent pickling liquor from iron smelting plants [8] Treatment ... for phosphate removal from aqueous solutions are discussed Experimental procedure Red mud was obtained from a bauxite ore refinery in Guinea It was analyzed using Emission Spectral Analyser PGS-2 ... The influence of the raw red mud dose on the PO removal (O-OPh, A-TPPh) In this paper the investigations on red mud wasted from Guinean bauxite and its utilization for phosphate removal from...
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Tài liệu Báo cáo khoa học: Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3¢-end of virus minus-strand RNA docx
Ngày tải lên :
20/02/2014, 01:20
... the minusstrand RNA being at that time unavailable In the present study we investigated the involvement of sequences and ⁄ or structures in RNA synthesis directed in vitro by HCV NS5B by using ... described in [13] (B) Secondary structure of a fragment spanning from nt 229–365 in domain II as described in [14] (C) Secondary structure of domain II, spanning nt 229–416, as described by in [13] ... synthesized in one round of synthesis, we performed RdRp assays in the presence of heparin in order to prevent reinitiation In a first step we determined the heparin concentration needed to prevent reinitiation...
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Tài liệu Báo cáo khoa học: Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins pdf
Ngày tải lên :
20/02/2014, 23:20
... bovine serum (FBS, hyClone, Utah, USA) containing 100 UÆmL)1 penicillin/streptomycin and mM L-glutamine at 37 °C under 5% CO2 The JAr and Jeg3 cell lines (ATCC) were maintained in Dulbecco’s minimum ... scanning microscopy Immunofluorescence was performed on choriocarcinoma cells (24 h in DMEM containing 10% FBS, 1% glutamine and 1% penicillin/streptomycin) and CHO cells (HAM’s F12 medium containing ... Cells were seeded in 6-well trays and incubated in F12K (BeWo) and DMEM (JAr and Jeg3) containing 10% lipoproteindeficient serum (open symbols) or in medium containing lipoproteindeficient serum...
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Tài liệu Báo cáo khoa học: Analyzing changes of chromatin-bound replication proteins occurring in response to and after release from a hypoxic block of replicon initiation in T24 cells pptx
Ngày tải lên :
21/02/2014, 00:20
... strong incorporation of [3H]Thd into growing daughter strands occurs, preferentially sedimenting in the first third of the gradient and attributable to short chains originating from newly initiated ... entering S-phase in succession Separating a cell fraction containing DNA bound proteins Entire replicative SV40 minichromosomes bearing functionally bound replication proteins can be eluted from ... chromatin cannot be eluted from isolated nuclei Interrupting the continuity of the DNA (e.g by suitable endonucleases) yields elutable chromatin fragments preferably originating from regions far from...
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Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt
Ngày tải lên :
18/03/2014, 01:20
... of kinase are limited in plants [17–21] The Ca2+/CaM kinase isolated from maize roots has been shown to be involved in gravitropism [19] and the Ca2+/ CaM kinase isolated from lily anthers binds ... with some DNA binding protein Antibodies alone showed no interaction with DNA We could not determine the direct binding of the purified kinase with DNA as we could not obtain the kinase preparation ... be an in vitro substrate for the PsCCaMK, the effect of phosphorylation on its DNAbinding property was tested The protein was in vitro phosphorylated using cold ATP and used for DNA binding studies...
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Báo cáo khoa học: The mitochondrial permeability transition from in vitro artifact to disease target ppt
Ngày tải lên :
30/03/2014, 11:20
... to identifying the signaling pathways linking myocardial protection to PTP inhibition, which may involve protein kinase Ce [217] and mitogen-activated protein kinase kinase [218] An integrated ... caused by the inhibition of calcineurin Lack of involvement of calcineurin had already been suggested by the findings (a) that the immunosuppressant FK506 (which inhibits calcineurin) failed to ... Overexpression of mitogen-activated protein kinase kinase in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo J Biol Chem 280, 669– 676...
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Báo cáo " Isomeranzin against Herpes simplex virus in vitro from Clausena heptaphylla (Roxb.) W. & ARN.: Isolation, structure and biological assay " potx
Ngày tải lên :
03/04/2014, 15:20
... to trace chemicals remaining from the extraction process, or from the compound itself is uncertain When the compound was dissolved in ethyl acetate, it was effective against both viruses, albeit ... cells were about 40% destroyed At this point in time viral growth had only been observed in cells treated with DMSO and infected with HSV-1 However, in other solvents with 1mg/ml compound, the ... spectacular effects against either virus in Vero cells, 0.5 mg/ml compound in 5% ethyl acetate or 0.25 mg/ml compound in 2.5% ethyl acetate generally provided about 40% protection from both HSV-1 and...
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báo cáo hóa học:" Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro" pdf
Ngày tải lên :
18/06/2014, 15:20
... Missouri, USA) for 90 minutes in CO2 incubator, at 37°C, in the dark After that, cells were washed in PBS 1× and cultured protected from light Stained stem cells were used in co-cultures of DMD ... tissue in vivo may differ from the observed in vitro Conclusion Our findings showed that umbilical cord blood CD34+ stem cells have the potential to interact with dystrophic muscle cells restoring ... were kept in an incubator at 37°C and 5% CO2 Myoblasts from DMD and DMB affected patients were obtained from biceps biopsies They were implanted into 25 cm2 plastic culture flasks (Corning, New...
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Báo cáo sinh học: "In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2" pot
Ngày tải lên :
18/06/2014, 19:20
... fixed in buffered formalin and embedded in paraffin a, b: Staining with H&E c, d: Specific brown staining of apoptotic cells by anti-caspase Ab e, f: In situ end-labeling (ISEL); black staining ... were washed and incubated with 2’, 5’diaminobenzidine (DAB, Vector Laboratories, Burlingame, CA) followed by counterstaining with hematoxylin Caspase staining was performed using an Ab specific ... (reviewed in [25] and [1]) In mouse systems, ex vivo transduction of chemokines into tumor cells has provided potent tumor vaccines inducing tumor rejection, which was mediated by infiltrating T...
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báo cáo hóa học:" Airborne particulate matter PM2.5 from Mexico City affects the generation of reactive oxygen species by blood neutrophils from asthmatics: an in vitro approach" docx
Ngày tải lên :
20/06/2014, 00:20
... (ROS) induce chemical and structural changes on human insulin in vitro, including alterations in its immunoreactivity Frontiers in bioscience 2005, 10:838-843 Olivares-Corichi IM, Ceballos G, Medina-Santillán ... asthma triggers including viral infections and air pollutants may activate the production of ROS, thus resulting in inflammation in addition to the asthmatic symptoms [26] The maintenance of basal ... Federal 2000–2006 Molina LT, Molina MJ: Cleaning the air: a comparative overview In Air Quality in the Mexico Megacity An integrated Assessment Edited by: Molina LT, Molina MJ Kluwer Netherlands:...
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báo cáo hóa học:" In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2" pptx
Ngày tải lên :
20/06/2014, 03:20
... fixed in buffered formalin and embedded in paraffin a, b: Staining with H&E c, d: Specific brown staining of apoptotic cells by anti-caspase Ab e, f: In situ end-labeling (ISEL); black staining ... were washed and incubated with 2’, 5’diaminobenzidine (DAB, Vector Laboratories, Burlingame, CA) followed by counterstaining with hematoxylin Caspase staining was performed using an Ab specific ... (reviewed in [25] and [1]) In mouse systems, ex vivo transduction of chemokines into tumor cells has provided potent tumor vaccines inducing tumor rejection, which was mediated by infiltrating T...
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Báo cáo khoa học: "Effect of β -mercaptoethanol or epidermal growth factor supplementation on in vitro maturation of canine oocytes collected from dogs with different stages of the estrus cycle" ppsx
Ngày tải lên :
07/08/2014, 18:20
... classification in canine oocytes stained after in vitro maturation Classification Description Germinal vesicle (GV) Germinal vesicle (nuclear envelope) still intact; scattered chromatin Germinal vesicle ... compound, to culture medium can increase the cysteinmediated GSH synthesis in bovine embryo produced in vitro Similarly, addition of β-ME increased intracellular GSH in mouse lymphocytes [37] It ... canine oocytes for use of in vitro experiment Glutathione (GSH) is the major non-protein sulfydryl compound present in mammalian cells Multiple actions have been described for GSH, including increasing...
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Báo cáo khoa học: "In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood" ppt
Ngày tải lên :
07/08/2014, 18:21
... ,etahpsohp lorecylg -β fo detsisnoc taht muidem noitcudni cinegoetso na desu ew ,sCSM eht morf noitaitnereffid cinegoetso ecudni oT laitnetop cinegoetso tibihxe sCSM doolb droC )A2 giF( nitnemiv dna ... ecnanetniam eht dna euqinhcet reporp eht ,erutluc yramirp ot gnilpmas morf emit eht taht thguoht saw tI ]72,22[ srotinegorp citeiopotameah rof esac eht sa emas eht ,srotinegorp lamyhcnesem ni ... ladiobuc wohs ton did sCSM BCU eht ,sCSM worram enob ekilnu ,revewoH )4 giF( )gniniats assoK-noV yb deifitnedi( laitnetop cinegoetso evah sCSM taht gnitseggus ,etitapayxordyh demrof sCSM BCU ehT enosahtemaxed...
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Báo cáo khoa học: "Suppressive effect of culture supernatant of erythrocytes and serum from dogs infected with Babesia gibsoni on the morphological maturation of canine reticulocytes in vitro" pdf
Ngày tải lên :
07/08/2014, 20:23
... setycoluciter eninac fo noitarutam eht dedrater yltnacifingis setycorhtyre fo tnatanrepus erutluc dna mures detcefni inosbig B oviv ni inosbig B ortiv nI inosbig B inosbig B ,inosbig B ortiv ni inosbig ... setycoluciter eninac fo noitarutam eht no snoitcarf rieht dna htiw detcefni sgod morf mures fo tceffe ehT t p p inosbig B inosbig B inosbig B inosbig B inosbig B ortiv ni giF setycoluciter eninac fo ... setycoluciter eninaC p ortiv ni inosbig B setycoluciter eninac fo noitarutam eht no htiw detcefni setycorhtyre fo tnatanrepus erutluc eht fo tceffE inosbig B htiw detcefni yllacinorhc sgod morf...
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Báo cáo sinh học: "In vitro activities of 18 antimicrobial agents against Staphylococcus aureus isolates from the Institut Pasteur of Madagascar" doc
Ngày tải lên :
08/08/2014, 19:20
... Penicillin Erythromycin Lincomycin Pristinamycin Kanamycin Tobramycin Gentamicin Ciprofloxacin Tetracyclin Minocyclin Trimethoprim-sulfamethoxazole Rifampicin Fusidic acid Chloramphenicol Fosfomycin ... France The following 18 antibiotics were tested: oxacillin, penicillin, erythromycin, lincomycin, pristinamycin, vancomycin, teicoplanin, ciprofloxacin, tetracycline, minocycline, trimethoprim-sulfamethoxazole, ... S I S R I KAN: kanamycin, TOB: tobramycin, GEN: gentamycin, TCY: tetracycline, MNO:minocyclin, ERY: erythromycin, LIN: lincomycin, PRI: pristiniamycin, CIP: ciprofloxacin, SXT: Trimethoprim-sulfamethoxazole,...
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