... combine the results of these studies in a summary statement Meta-analysis is the method of combining results of multiple studies in a statistically valid manner to determine a summary measure of ... the goals of imaging and the search methodology The chapter is then broken down into the clinical issues Discussion of each issue begins with a brief summary of the literature, including a quantification ... estimation of the value of a research report for guiding clinical practice The method used in this book is derived from that of Kent et al (25) and is shown in Table 2.1 Use of such a grading scheme is...
Ngày tải lên: 30/05/2014, 23:55
Báo cáo hóa học: " Reversal of TMS-induced motor twitch by training is associated with a reduction in excitability of the antagonist muscle" ppt
... amplitude following minutes of training, associated with wrist movement, in direction opposite to that of original TMSinduced twitch Page of motor skill acquisition [14-19], through unmasking of latent ... defined as the muscle opposing the direction of training Resting motor threshold (RMT), defined as the minimum TMS intensity that evoked a MEP of at least 50 μV peak-to-peak amplitude in of 10 ... the training muscles was continuously monitored during practice to provide visual feedback during the experiment and ensure regular contractions during training In this study the antagonist muscle...
Ngày tải lên: 19/06/2014, 08:20
In order to become competent in a foreign language, it is important for language learners not only to acquire new vocabularies and a new set of phonological and syntactic rules but also to learn what Wilson (1986)
... Phước, Tây Ninh thành phố Hồ Chí Minh; ĐBSCL gồm tỉnh Long An, Tiền Giang, An -18- Giang, Kiên Giang, Cà Mau, Sóc Trăng, Bạc Liêu, Đồng Tháp, Bến Tre, Hậu Giang, Vónh Long, Trà Vinh thành phố ... lớn, nước ròng… Nam Bộ vùng đất đa dạng sinh học Khí hậu - thuỷ văn tạo điều kiện cho động thực vật sinh sôi nảy nở, thích hợp cho việc phát triển nguồn sinh vật cạn nước, thuận lợi cho canh tác ... lớn nước Ven biển có rừng ngập mặn rộng lớn Từ Cà Mau đến Kiên Giang có rừng nguyên sinh U Minh Thượng, U Minh Hạ Rừng có nhiều loài động thực vật quý Hình ảnh quen thuộc sân chim, kèo ong, sếu...
Ngày tải lên: 17/04/2013, 16:09
Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx
... involved in the formation of glucuronate Interestingly, vitamin C formation is induced in Gunn rats by phenobarbital [8], an inducer of UGT2s, which is indirect evidence for the involvement of ... presence of ATPMg It is shown below that this is due to loss of the inhibitory effect of ATP-Mg, consequent to the removal of a heat-stable cofactor present in the highspeed supernatant Accordingly, ... the ability of this nucleotide to stimulate UDPglucuronate in ux into microsomes [11] This involves conversion of UDP-glucuronate to UMP in the lumen of the vesicles and exchange of the latter...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... enterotoxin in human intestine and in a human intestinal cell line (Caco-2) J Cell Physiol 156, 138–144 20 Cohen, M.B., Hawkins, J.A & Witte, D.P (1998) Guanylin mRNA expression in human intestine ... desensitization of these receptors GC-A is phosphorylated on six serine and threonine residues present in the protein kinase-like domain in the basal state [2] Mutation of any of these sites to alanine led ... antibody raised to the protein kinase-like domain of GC-C [32] or with GC-C:4D7 antibody preadsorbed with a fusion protein of the kinaselike domain of GC-C and glutathione S-transferase, in blocking...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo Y học: Proteasome-driven turnover of tryptophan hydroxylase is triggered by phosphorylation in RBL2H3 cells, a serotonin producing mast cell line pptx
... 32P-Loading was further continued for 120 in the presence of protein-kinase inhibitors or proteinphosphatase inhibitors Cells were then rinsed with NaCl/Pi and disrupted with 1% NP-40 in 50 mM Tris/HCl ... in the absence of proteasome inhibitors (lane in Fig 1B, 32P vs WB) Inhibition of TPH degradation in the cell-free proteasome system by protein kinase inhibitors We examined the involvement of ... The cells were then disrupted with 1% NP-40 in 50 mM Tris/HCl (pH 7.8) containing the protease inhibitor cocktail (32P): In order to examine 32P-incorporation into proteins, the cell extracts...
Ngày tải lên: 08/03/2014, 16:20
Mobil 1 is original equipment in some of the world’s finest vehicles, including potx
... wheelbearing grease in the landing gear, leading to bearing failure ExxonMobil devised a way of synthesizing grease that retained its lubricating characteristics over a wider range of temperatures ... tolerance and improved machining of today’s engines, the traditional concept of “break -in is not as critical However, if the engine rebuilder is using older machining equipment or lower-quality ... on engine parts to prevent metal-to-metal contact, Mobil has a high viscosity index and resists being squeezed out of the contact area between metal surfaces by maintaining its viscosity This helps...
Ngày tải lên: 08/03/2014, 19:20
To Cut or Not to Cut? That is the (Central Bank’s) Question In Search of the Neutral Interest Rate in Latin America pdf
... has maintained financial intermediation in Reais, it has created a system of unusually short duration financial contracts The legacy of indexation to the overnight interest rate has created institutional ... accommodative and envisions a pickup in economic growth—though somewhat slower in this cycle, reflecting the effect of rising non-performing loans on the transmission of monetary policy to lending rates ... currency mismatches by forcing the banking sector to internalize the currency risk As it was recently used in Brazil and Peru, this is achieved by equalizing the rates of return of credit in different...
Ngày tải lên: 15/03/2014, 14:20
Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc
... TAgPuPuT [19] It is interesting that the )10 sequence is located inside the iron box of desA (nucleotides 7–12 of the iron box), explaining the regulation of desA expression by binding of DmdR1 to ... in humans Initial work on the biosynthesis of desferrioxamine B in S pilosus indicated that the first step in the desferrioxamine biosynthesis is the decarboxylation of lysine by a lysine decarboxylase ... palindromic region, which contains the repressor-binding site, is boxed, and the ribosome-binding site is underlined The ATG is shown in bold letters The reported transcription start site of...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: RCAN1-1L is overexpressed in neurons of Alzheimer’s disease patients pot
... localization of these isoforms in the brain In order to try to understand how these isoforms may differ, we examined the expression of the isoforms known to be transcribed in brain tissue, isoforms ... rigorously tested Discussion RCAN1 has been shown to bind to and inhibit the serine–threonine protein phosphatase calcineurin [5] The brain is an especially interesting organ in which to examine RCAN1 ... changes in the brains of mice lacking calcineurin A alpha J Neurochem 68, 1668– 1678 1724 14 Goto S, Matsukado Y, Mihara Y, Inoue N & Miyamoto E (1986) The distribution of calcineurin in rat brain...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: Knock-out of the chloroplast-encoded PSI-J subunit of photosystem I in Nicotiana tabacum PSI-J is required for efficient electron transfer and stable accumulation of photosystem I pot
... Cyt c6 and was explained by a displacement of this domain Thus, PSI-J does not appear to participate directly in binding of Pc or Cyt c6, but plays a role in maintaining a precise recognition site ... marinus (PROMA)] Amino-acid residues involved in Chl binding [W (Trp), E (Glu) and H (His)] are indicated with green arrows Note that the histidine residue is only conserved in cyanobacteria, in ... values were obtained using chemical oxidation and reduction of P700 (data not shown) This clearly indicates an % 20% reduction in P700 in plants lacking PSI-J To investigate this by an independent...
Ngày tải lên: 16/03/2014, 11:20
Neither of the children is interested in learning pptx
... đứa bọn trẻ - is interested in learning” – thích học Cấu trúc từ “to be interested in + Ving” = “to be fond of + V-ing” = “to be keen on + Ving” – thích, hứng thú làm việc Ở “learning” danh động ... thêm chi tiết từ đó) Neither of the children is interested in learning 2 Các bạn di chuột vào cụm từ để biết chức cụm câu: Neither of the children is interested in learning 3 Tại câu lại dịch vậy? ... “neither of ” động từ chia số hay số nhiều Ví dụ: “Neither of the children is (are) interested in learning” Không đứa bọn trẻ thích học • Các hình thức liên quan khác - Sau “neither of đại từ...
Ngày tải lên: 20/03/2014, 00:20
Báo cáo khoa học: The pivotal regulator GlnB of Escherichia coli is engaged in subtle and context-dependent control potx
... glnK is not expressed in this medium Closed circles depict WCH15 grown in the presence of the indicated concentration of IPTG; the black line is a result of a linear regression calculation of the ... transduction in vivo Statements like this protein is or is not involved not sufce if subtlety of regulation is the issue The relative extents to which the various proteins control signal transduction in ... importance of GlnB, the cascade must be studied in a wild-type chromosomal background Although helpful, a deletion strain missing one of the proteins operating in the cascade will not yield denitive information...
Ngày tải lên: 23/03/2014, 04:21
Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... levels of hDlg protein in the human epithelial cell line HeLa We report a strong decrease in hDlg protein, although this event is independent of its phosphorylation state Moreover, this hDlg ... activation of caspase being stronger and sustained over time In addition, the length of activation of caspase is similar to the time course of hDlg degradation, indicating that this caspase may ... any of the experimental conditions described (Fig 2E), which is consistent with the lack of hDlg degradation observed in this cell line The low percentage of HEK293 cells undergoing apoptosis...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: Hydrogen bond residue positioning in the 599–611 loop of thimet oligopeptidase is required for substrate selection pdf
... possible role of this residue in catalysis in more detail Discussion A major finding of this study is that the bradykinin analogue mcaBk can still be cleaved efficiently after 5612 removal of the Tyr ... intermediate via hydrogen bond donation This role is similar to that of other amino acid residues in peptidases, such as His231 in thermolysin [17,18] However, modeling suggests that Tyr612 of ... fitting domains I and II to the structure of DcP The identification of the appropriate clipping points was aided by using the Alternate Domain Fit tool from the suite of tools within the swiss-pdbviewer...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
... sialidase often interrupts binding In particular, an arginine residue within the first Ig domain is a key aminoacid residue for binding to SIA [2] Comparison of the N-terminal Ig-like domain (Ig-D1) of ... siglec-10 protein The binding of SHP-1, however, was missing from the Y667F mutant indicating this to be the preferred tyrosine for interaction with SHP-1 SHP-2 binding, however, was only diminished by ... the sialoadhesin family of I-type lectins Sialic acid linkage and substructure requirements for binding of myelinassociated glycoprotein, Schwann cell myelin protein, and sialoadhesin J Biol Chem...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo khoa học: The GxxxG motif of the transmembrane domain of subunit e is involved in the dimerization/oligomerization of the yeast ATP synthase complex in the mitochondrial membrane doc
... membrane-spanning segment of the b-subunit (subunit 4) and (b) inter-ATP synthase cross-linking with a bis-maleimide reagent and involving a cysteine residue introduced into the C-terminal part of subunit ... NEM instead of CuCl2 Cross-linking conditions are described in the experimental procedure After dissociation of samples with SDS in the presence of 20 mM of NEM, aliquots (30 lg of protein) were ... devoid of Cys28 (not shown), thus indicating the involvement of Cys28 in the formation of the adduct The 21.4-kDa band corresponded to a homodimer of subunit e resulting from the formation of a disulfide...
Ngày tải lên: 31/03/2014, 01:20