imaging the dynamics of mammalian neocortical population activity in vivo

... of nitrate of leaf NR activity of nodulafed plants Administration of mM NaN0 to 11 mo old nodulated plants did not increase leaf NR activity, whereas the 10 mM NaN0 dose induced high enzyme activity ... activity decreased in the previous leaf and the highest enzyme activity was found again in the new leaf (Fig 2) When the nitrate supply was withdrawn, the enzyme activity recovered its minimum value ... NR activity (6-9 nmol N02-mg- measured in vivo in the leaves of young nitrogen-deficient R pseudoacacia; its role is unknown, but its decrease, concomitant with the advent of the N activity, indicates...

Ngày tải lên: 09/08/2014, 04:20

... said the midwife, meaning the father (3 – 4) 24 After this, the point of view changes to the father of the child The switch from the narrator to other points of view is rather rapid and confusing ... the theme of child abuse in Shadow Theatre The study of the selected novels reveal that the strategies of lexical borrowings, code-switching, code-mixing and the use of different levels of SingaporeMalayan ... trapped in the teachings of Buddha Although Mr K.’s love for the sounds of the storm and the waves connect him to Hung, who hears the passion in the muezzin’s call and the sound of rain in his mind,...

Ngày tải lên: 16/09/2015, 08:30

... resistant strains appeared frequently in European vineyards Since the discontinuation of the use of benzimidazoles to control B cinerea in 1975, the frequency of MBC-resistant strains decreased ... and efficacy of the reaction was calculated Melting temperature of the product was determined by dissociation of DNA during heating resulting in a reduction of the fluorescence signal The first ... active ingredient introduced to the market INTRODUCTION The aims of the present study were as follows: - Determination of the influence of resistance management strategies for benzimidazoles on populations...

Ngày tải lên: 19/11/2015, 15:46

... represents the inertial filling in of dips and knocking out of bumps on the ‘bare’ surface caused by rolling grains flowing over the top The λρ(|h x | − tan α) term represents the tendency of flowing grains ... evolves under the in uence of two distinct types of mechanism Firstly, the impact of a constant flux of saltating grains knocks grains out of the ‘bare’ surface, causing them to hop along the ripple ... revealed the same trend 11.4.2 Homing in on the physics: a discussion of smoothing in Case B We focus in this section on the physics of the equations and the results In the regime of continuous...

Ngày tải lên: 01/11/2013, 08:20

... choose the following method of mitigating the problem of changing sample composition: Instead of the exposure levels Xi (t), we investigate the change in the exposure of the same bank, as stated in ... investigate the determinants of the banks’ exposure to interest rate risk They find that the belonging to certain banking groups, the banks’ size, their earnings and balance composition, and the ... positions in their banking book Our dataset concerning the Basel interest rate coefficient consists of two sources: the notifications in the event that the losses exceed 20% of the own funds, and the information...

Ngày tải lên: 16/02/2014, 06:20

... avoid treating their networks of relationships as if they were a web of zero-sum games—repeatedly trading off the interests of one stakeholder in favor of the interests of another We further recommend ... further actions This is not the first foray into the topic of trust by either organization Since its founding in 2004, the Institute has made trust the overarching theme of its work, which includes ... Professor of Business Administration Darden School of Business, University of Virginia Jared Harris Assistant Professor of Business Administration Darden School of Business, University of Virginia...

Ngày tải lên: 18/02/2014, 00:20

... Thus, integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling Similarly, sensing of glutamine-induced hepatocyte swelling by integrins feeds into ... Osmosensing and signaling in mammalian cell function F Schliess et al [7] On the other hand, hyperosmotic shrinkage prevents insulin-induced hepatocyte swelling and proteolysis inhibition, indicating ... swelling [12,13], insulin-induced hepatocyte swelling is registrated by the integrin system, leading to a Src-dependent activation of the p38-type MAPK and thereby inhibition of 5800 autophagic...

Ngày tải lên: 18/02/2014, 16:20

... capacity to fund their own retirement but the overall increase in assets and income masks increasing inequities While the incomes of those older people in the top 25 per cent of the income distribution ... (Mackinnon et al in press) Lifelong learning The increasing numbers of older people offer a growing market for education and training Lifelong learning is important, not only for staving off cognitive ... increasing number of older women are in the workforce, which may blur the traditional division of labour where the wife runs the home, considering it ‘her domain’, and resents the intrusion of...

Ngày tải lên: 05/03/2014, 18:20

... for the small values in residue 2, which agrees with the expected exibility of the N-terminal region of the protein The difference of S2 values in the presence and absence of solute are shown in ... changes in the dynamic properties of the protein rather than by changing the structure of the protein itself In fact, protein function depends vitally on its structure and dynamics; if a stabilizing ... in which the dynamics of a protein are investigated in different conditions invariably nd increases in correlation times upon ligand binding which are interpreted in the light of the higher mass...

Ngày tải lên: 07/03/2014, 21:20

... could then be cleaved to yield the desired modules This suggests that the CUB2 domain might have a chaperoning role in the folding of the CCP1 By contrast, interdependence of the two CCP modules in ... present in duplicate copies within the C1 complex, forming a tetramer Both the autoactivation of C1r and the activation of C1s require large-scale movements of the different domains of the proteases ... of a tyrosine in strand C of CCP4 in place of an asparagine in C1r CCP2 (N379), and based on the results of the present perturbation study, we suggest that the inter-CCP flexibility in C1r is...

Ngày tải lên: 15/03/2014, 23:20

... subdomain 1, where the spin probe is attached, is not directly involved in the intermonomer cross-link, because one of the cross-linking sites is occupied by the spin probe, therefore, the rigidity ... complexes the motion of the probe is less restricted relative to the strong binding state and there is no difference between the two weak binding complexes In the case of cross-linked F-actin, the ... study, the interaction of ATP and S1 with actin during activation of myosin S1 ATPase using caged ATP did not produce an increase in rotational motion in the environment of the Cys374 site of actin...

Ngày tải lên: 16/03/2014, 13:20

... derivatives thereof, while maintaining the hydrophobicity of the binding site To test the effect of the mutations on the specificity for phenylacetylated substrates, the steady-state kinetic parameters ... more insight into the structural features underlying the kinetic properties of these enzymes The reduced amidase activity of bF24A in uences the factor a, a key parameter for the synthesis of antibiotics ... applicability in the synthesis of other antibiotics First the factor a was determined by measuring the steady-state kinetic parameters of bF24A for the hydrolysis of other relevant synthetic acyl...

Ngày tải lên: 17/03/2014, 23:20

... from the gut to the liver in CMR in the postprandial phase In this study, we investigated the effects of CMR on NF-jB activation in macrophages and determined whether these are modulated by the ... is in uenced by the fatty acid composition of the particles Phosphorylation of p65–NF-jB plays a critical role in regulating its transcriptional activity To further investigate the effects of the ... degradation of IjBa, thus allowing translocation of NF-jB to the nucleus [20] To determine whether modulation of IjBa serine phosphorylation status plays a part in mediating the inhibitory effects of...

Ngày tải lên: 23/03/2014, 04:20

... [48] In this study, we showed that the lack of five amino acids (LECLQ) in the D region of EcR did not affect the ligand– receptor binding, the heterodimerization of EcR and USP, or the binding of ... determined at the step of their binding to the EcR–USP complex 4100 C Minakuchi et al (Eur J Biochem 270) Ó FEBS 2003 Fig Binding of ponasterone A (PoA) to the inherent receptor proteins in the ... [25,27–29,50] As shown in Fig 7, the binding activity (pIC50) is highly correlated with the molting hormonal activity (pEC50), indicating that the strength of the hormonal activity of ecdysone agonists...

Ngày tải lên: 23/03/2014, 21:20

... be shopping online or reading email We report on these and other findings in the following sections We first survey the related work in section We then describe the characteristics of the incentivised ... behavior in section Next we concentrate on the various aspects of the recommendation success from the viewpoint of the sender and the recipient of the recommendation in section The timing and the ... models of adoption we discuss The Dynamics of Viral Marketing next Most of the previous research on the flow of information and in uence through the networks has been done in the context of epidemiology...

Ngày tải lên: 29/03/2014, 23:20

... amplification In vitro conversion of recombinant PrP or PrPC in the absence of PrPSc An alternative strategy for the de novo generation of PrPSc in vitro involves the conversion of PrPC or rPrP in the ... where the physical properties of PrPres are expected to mimic that of PrPSc seeds, conversions in the absence of PrPSc pose uncertainty regarding the conformation of the final products of the reaction ... which occurs on the pathway of conversion from the cellular isoform of the prion protein (PrPC) to the disease-associated isoform of the prion protein (PrPSc) Yet-unidentified cellular cofactors may...

Ngày tải lên: 30/03/2014, 09:20

... cope with devastation in the inner city, the size of the problem dwarfs the size of the response Initiatives like these often prompt observers to wonder if the purpose of the program is to provide ... history of unjust treatment of persons of color Then, beginning in the mid-1970s, in a more conservative political climate, the government began to take back these hard-won gains 30 The Dynamics of ... 39 origins in the late nineteenth century, the twin pressures of containment and change have made social work, like the welfare state, an arena of struggle Reflecting the mandates of the profession...

Ngày tải lên: 11/06/2014, 10:17

... JNHT]), the introduction of archaeology at the University of the West Indies in 1987, and improvements in the training of Jamaican archaeologists The past decade has seen increased interest in Jamaican ... decade The second article, “Taíno Settlement of the Kingston Area”, reports on a survey of eighteen sites in Kingston The authors examine the findings of two pilot studies, an examination of the ... ACKNOWLEDGEMENTS Introduction IN JAMAICA, THE indigenous population is still being referred to as the Arawaks, despite the adoption of the term Taínos to distinguish the native population of the Greater...

Ngày tải lên: 11/06/2014, 12:49

... by using this method One is the level of fishing effort (FMSY ), which is associated with overfishing, or the process of taking out more than the MSY level of harvest The other is the size of the ... of change and interactions that occur at different levels of analysis, including the economics of the fishing industry, the politics of domestic agenda setting, and the relations of international ... changes in the status quo However, it cannot provide unambiguous evidence regarding the role of a regime in maintaining species or stocks of individual species in a healthy condition The range of...

Ngày tải lên: 11/06/2014, 13:22