... arrows). (C–E) Staining of sPLA 2 -V in three active RA tissues. In all cases, intense staining of the granulation tissue in the sublining interstitium was evident. Staining of the granulation tissue ... v) bovine serum albumin (for blocking) containing 0.1% (w ⁄ v) saponin (for permeabilization) in NaCl ⁄ P i for 1 h, with anti-sPLA 2 and anti-COX-2 1 h in NaCl ⁄ P i con- taining 1% albumin (1 ... sublining region showed intense staining (Cd, orange arrowheads). Although cartilage chondrocytes were negative, fibroblasts in ltrating into the cartilage were intensely stained (Eb). sPLA2s in...
Ngày tải lên: 19/02/2014, 16:20
... patients contain increased concentrations of sev- eral chemokines, such as interleukin (IL)-8) ⁄ CXCL8, interferon-c (IFN-c)-inducible protein-10 ⁄ CXCL10, monokine induced by interferon-c ⁄ ... involved in the joint degrada- tion process in RA. Thus, MCP-4 ⁄ CCL13 might have roles not only in the proliferation of synovial cells but also in the invasion of synovial cells, resulting in ... (1998) Chemokines ) chemotactic cytokines that mediate in ammation. N Engl J Med 338, 436–445. 6 Koch AE (2005) Chemokines and their receptors in rheumatoid arthritis: future targets? Arthritis...
Ngày tải lên: 16/03/2014, 05:20
Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf
... and IFN-c. (B) Chemokines expressed in the joint recruit leukocytes into the joints. In addition to functioning in cell trafficking, several chemokines have other biological abilities. Chemokines stimulate FLS ... Leonard EJ, Inoue K & Kashiwazaki S (1993) Monocyte chemoattractant protein-1 (MCP-1) in inflammatory joint diseases and its involvement in the cytokine network of rheumatoid synovium. Clin Immunol ... Ruth JH, Volin MV, Haines GK 3rd, Woodruff DC, Katschke KJ Jr, Woods JM, Park CC, Morel JC & Koch AE (2001) Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced...
Ngày tải lên: 18/02/2014, 18:20
Rheumatoid arthritis - The management of rheumatoid arthritis in adults doc
... take part in existing educational activities, including self-management programmes. NICE clinical guideline 79 – Rheumatoid arthritis 4 Introduction Rheumatoid arthritis (RA) is an inflammatory ... characteristics to inform their decisions for individual patients. NICE clinical guideline 79 Rheumatoid arthritis: The management of rheumatoid arthritis in adults Ordering information You ... guideline 79 – Rheumatoid arthritis 15 or adding an NSAID or COX-2 inhibitor (with a PPI) if pain relief is ineffective or insufficient. 1.4.4.6 If NSAIDs or COX-2 inhibitors are not providing...
Ngày tải lên: 08/03/2014, 14:20
IMAGING AND RADIOANALYTICAL TECHNIQUES IN INTERDISCIPLINARY RESEARCH -FUNDAMENTALS AND CUTTING EDGE APPLICATIONS potx
... resonance imaging machine [16]. Imaging and Radioanalytical Techniques in Interdisciplinary Research - Fundamentals and Cutting Edge Applications 42 Imaging and Radioanalytical Techniques in Interdisciplinary ... (P-32) in rats [7]. The major development of scintigraphic imaging started with the invention of the gamma camera by Anger in 1956 [1]. In parallel, positron imaging was developed. Both imaging ... system used. In two dimensional PET imaging, only lines of response lying within a specified imaging plane are considered (Figure 8, b). The lines of response are then organized into sets of...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis pdf
... Firestein GS (1991) Cytokines in chronic in ammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte–macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis ... signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis. Arthri- tis Rheum 43, 2501–2512. 24 Harris ED Jr (1990) Rheumatoid ... MLN51 GM-CSF WB MLN51 GM-CSF A B C E D MLN51 β -actin β -actin β -actin β -actin β -actin β -actin β -actin β -actin – + – + α -amanitin WB RT-PCR CHX GM-CSF – + – + MLN51 MLN51...
Ngày tải lên: 23/03/2014, 07:20
Computational intelligence in medical imaging techniques and applications
... Evolutionary Computing and Its Use in Medical Imaging 35 3 2 1 Before spinning 3 2 1 After spinning FIGURE 2.9: SUS selection. These effects are overcome using stochastic universal selection ... but instead of using a single pointer, N equally spaced pointers are used for a population of N individuals, and the wheel is spun only once (Figure 2.9). Instead of using the fitness of an individual ... generation rank i : rank of individual i within the population in a generation N: number of individuals within population So, instead of using the raw fitness to determine the proportion for an individual, the...
Ngày tải lên: 29/04/2014, 09:47
báo cáo hóa học:" Septic arthritis in patients with rheumatoid arthritis Abdulaziz Al-Ahaideb" doc
Ngày tải lên: 20/06/2014, 01:20
Special Imaging Techniques
... of a fingerprint, (a), contains ridges that are many pixels wide. The skeletonized version, (b), contains ridges only a single pixel wide. a. Original fingerprint b. Skeletonized fingerprint islands ... Processing436 larger, as shown in Fig. 25-9b. However, the signal is becoming larger faster than the noise, resulting in an overall improvement in the SNR. Don't be confused into thinking that ... understood in the domain where the information is encoded. For instance, audio signals should be dealt with in the frequency domain, while image signals should be handled in the spatial domain. In spite...
Ngày tải lên: 13/09/2012, 09:50
Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
... safety-related conditions including hospitalized infections, myocardial infarction, stroke, gastrointestinal perforation, gastrointestinal bleeding, and fractures [5-14]. In validation studies, ... RA: rheumatoid arthritis; Se: sensitivity; Sp: specificity; VARA: Veterans Affairs Rheumatoid Arthritis Registry; VHA: Veterans Health Administration. Competing interests corresponding performance ... with clinical trials methodology where patients who do not adhere to the study protocol, including continuing to take the medication, are generally excluded from continuing to participate in the...
Ngày tải lên: 25/10/2012, 10:45
596 THE USE OF RELATIONSHIP MARKETING TECHNIQUES IN HIGHER EDUCATION A CASE STUDY
... tin tư liệ u. - 22 - 1.3. Kinh nghiệm về chiến lược Marketing du lịch của các nước 1.3.1. Chương trình chiến lược Marketing du lịch hiện đại: Qua thời gian, quan điểm của Marketing ... 11 1.3 Kinh nghiệm về chiến lược Marketing du lịch của các nước 12 1.3.1 Chương trình chiến lược Marketing du lịch hiện đại 12 1.3.2 Kinh nghiệm thực hiện chiến lược Marketing du lịch ... lược Marketing không có yếu tố tình cảm sẽ không hiệu quả. BỘ GIÁO DỤC & ĐÀO TẠO TRƯỜNG ĐẠI HỌC KINH TẾ THÀNH PHỐ HỒ CHI MINH LÊ MẠNH HÀ ĐỊNH HƯỚNG CHIẾN LƯỢC MARKETING DU...
Ngày tải lên: 08/04/2013, 17:02
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