... zero even at the 95% level in Canada, Finland, the Netherlands, Norway, Sweden, Switzerland, the UK and the US Moreover, while in some countries, (including Finland, the UK and the US) residential ... also for these countries the existence of cointegration could not be rejected We therefore specify the VAR models in the level of the variables Nevertheless, we neither impose the number of cointegrating ... to offset the macro economic effects of the collapse of the bubble).2 Of course, it is by no means clear that central banks are better able to judge the appropriate level of asset prices and the...
Ngày tải lên: 24/10/2012, 09:40
... lower than both the wild-type protein and mutants E142O and K133A Thermal analysis of protein unfolding The DSC curves of the wild-type protein and the mutants K133A, E142O, W140A and W140O are ... K133A, W140A and W140O The fluorescence spectra of E142O and K133A are similar to that of the wild-type protein However, the fluorescence in the mutants without tryptophan at 140 (W140A and W140O) ... change in the hydrophobic environment surrounding W140 and thus indicate a change in the overall (tertiary) structure of the protein Figure shows the fluorescence spectra of wild-type SNase and the...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo khoa học: Global shape and pH stability of ovorubin, an oligomeric protein from the eggs of Pomacea canaliculata pot
... structure The high stability of ovorubin oligomers might be due to a shift of the pK of the amino acid residues beyond 12, owing to their involvement in salt bridges At acidic pH, the stability of ovorubin ... giving the best fit to the scattering intensity The resulting dummy atom model represents the shape of the scattering particle To increase the reliability of the results, the final model for the dummy ... comparison with the one obtained at pH 6.0 No preferential loss of signal in the region of any of the aromatic residues was observed, suggesting a global loss of the tertiary structure of ovorubin...
Ngày tải lên: 07/03/2014, 06:20
Báo cáo khoa học: Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis doc
... connected to an increased thermostability of the protein itself, we monitored the thermal unfolding of WT and YQ proCPU-CHis Compared with the WT, the midpoint temperature (Tm) of the protein-unfolding ... demonstrated similar Km values of the native and WT, and the YQ mutant CPU with a synthetic and physiological substrate of CPU There seem to be no major changes in the positioning of the propeptide, as indicated ... instructions Expression of mutant proCPUs in insect cells Determination of the half-life (T1/2) of CPU’s activity The T1 ⁄ of the activity of the best mutants secreted in the supernatant of the cells in...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Local stability identification and the role of key acidic amino acid residues in staphylococcal nuclease unfolding ppt
... capacity (DCp) and difference of DCp of mutant from wild-type (%) were determined and the results for the wild-type protein and 20 mutants are given in Table The DHcal and Tm of the wild-type protein ... 33% lower than that of the wild-type protein The thermodynamic parameters of the glycine sustitution mutants also differed greatly from the wild-type protein The Tm values of these mutants ranged ... calculated based on the description of Privalov and Potekhin [6] residue substitution on the destabilization of secondary structure that leads to the large perturbation of the stability of the protein...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Effects of the G376E and G157D mutations on the stability of yeast enolase – a model for human muscle enolase deficiency pdf
... introduced alanine at these two positions, with the aim of determining whether any of the observed effects were a result of changes in the size and charge of the amino acid at these positions Results ... the conformation of this loop Changes in the conformation of the backbone at this point and changes in the orientation of other side chains, as a result of the introduction of the large charged ... markers of 97, 66, 45, 31, 21 and 14 kDa Lanes and 3, G157D Lanes and 5, G376E Lanes 6, and 8, wild-type Fig Thermal denaturation of wild-type enolase and its variants, as monitored by the CD...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae potx
... addition, the effects of reciprocal mutations of two non-conserved DNA binding site residues (VsEndA, Q69N and K71N; VcEndA, N69Q and N71K) on the kinetics, thermostability and salt dependence of these ... 4A,D) The results of the present study show that the Km values are strongly affected by the NaCl concentration, similar to the surface charge of the enzyme The higher positive charge of VsEndA therefore ... mutations are not in the immediate vicinity of the active site situated at the bottom of the positively charged pocket, but are still likely to affect the shape, stability and charge of the DNA binding...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx
... in the range 15) 60 C The results of the analysis of these curves using the linear extrapolation model (LEM) are shown in Tables and and Fig 4AC There is a slight temperature dependence of the ... the interaction of the 4Â-PP group with the polypeptide backbone and its effect on the stability of holo-ACP The average major conformation of the holo-ACP NMR structure was analyzed for ligandprotein ... regulated The differences in stability between the two proteins (as indicated by the values of DGwater, Cm and Tg) hence arise from the changes in the surface of the protein because of the interactions...
Ngày tải lên: 16/03/2014, 10:20
Role of an electrolyte and substrate on the stability of porous silicon
... cmÀ2) Decay of PL intensity is a good indication of the stability of porous silicon particularly of the surface bond configurations [3,16] In Fig 4(A), decay of the PL intensity at the peak wavelength ... The photochemical etching method with H2O2 solution does not generate a toxic material unlike in the case of HNO3 [11] Moreover, the addition of H2O2 to the etching mixture raises the pH of the ... structure of PS leads to an enormous increase in surface area and the presence of large number of unpaired bonds at the surface which alter the surface recombination rates and consequently the PL...
Ngày tải lên: 16/03/2014, 15:19
Báo cáo khoa học: Analysis of the stability of the spermadhesin PSP-I ⁄ PSP-II heterodimer Effects of Zn 2+ and acidic pH pdf
... [24], and the C1s protease of the C1 complex of complement [25] Thus, the Trp band can be regarded as a characteristic fingerprint of the native fold of PSP-I and PSP-II The near-UV CD spectra of the ... reversed by the addition of EDTA to the sample (Fig 2A) On the other hand, no significant decrease in the heterodimer stability was observed in the presence of mm CaCl2 (Table 1), emphasizing the specificity ... Thus, the dissociation of the PSP-I ⁄ PSP-II heterodimer in the female genital tract may be of physiological significance It may be of relevance for the regulation of the duration and magnitude of...
Ngày tải lên: 23/03/2014, 15:21
Báo cáo khoa học: Role of the surface charges D72 and K8 in the function and structural stability of the cytochrome c6 from Nostoc sp. PCC 7119 potx
... neutralization of the effect of the mutation D72K on the protein’s global charge was not sufficient to fully reverse the negative effect on the stability of cyt c6 The apparent stability of the mutants ... residues K8 and D72 are located near the crossing region of the helices, and the Nx atom of K8 is found ˚ at a distance of 6.2 A from the nearest side-chain oxygen of D72 Taking the functionally and ... electrostatic interactions of the side-chain of D72 that contribute to the stability of cyt c6 are at least partially local, and that the adverse effects of the mutations D72K and D72N cannot be entirely...
Ngày tải lên: 30/03/2014, 20:20
regional business cycle and real estate cycle analysis and the role of federal governments in regional stability
... (1982), and Cambell and Mankiw (1987) assume the stationarity of the rst log difference of the real GDP and emphasize on the usage of ARIMA models in an attempt to estimate the long-term trend of ... well as the U.S on aggregate exhibited distinct downturn of the real estate cycle between the third quarter of 2006 and the rst quarter of 2007 Finally we found that the state level economic and ... proximity from the economically dominant states plays quite a signi cant role in the formation of the business cycle patterns of the former group of states The business cycle patterns of the major...
Ngày tải lên: 03/06/2014, 02:10
Báo cáo hóa học: " Comment on “on the stability of quadratic double centralizers and quadratic multipliers: a fixed point approach” [Bodaghi et al., j. inequal. appl. 2011, article id 957541 (2011)]" pot
... stability of the quadratic functional equation Since then, the stability problems of various functional equation have been extensively investigated by a number of authors [8-20] Stability of quadratic ... Park et al Journal of Inequalities and Applications 2011, 2011:104 http://www.journalofinequalitiesandapplications.com/content/2011/1/104 Page of By (2.6), the right-hand side of the above inequality ... (3:8) for all a, b ∈ A and λ ∈ T Letting b = in (3.8), we have T(la) = l2T(a), for all a, b ∈ A and λ ∈ T Now, it follows from the proof of Theorem 2.1 and the continuity f and j that T is ℂ-linear...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: " Research Article On the Stability of Quadratic Double Centralizers and Quadratic Multipliers: A Fixed Point Approach" potx
... “On the stability of the linear functional equation,” Proceedings of the National Academy of Sciences of the United States of America, vol 27, pp 222–224, 1941 Th M Rassias, “On the stability of ... A Baker, The stability of the cosine equation,” Proceedings of the American Mathematical Society, vol 80, no 3, pp 411–416, 1980 15 M Eshaghi Gordji and A Bodaghi, “On the stability of quadratic ... A and λ ∈ T Letting b in 3.14 , we have L λa λ2 L a , for all a, b ∈ A and λ ∈ T Now, it follows from the proof of Theorem 2.1 and continuity of f and φ that T is C-linear If we substitute c and...
Ngày tải lên: 21/06/2014, 05:20
ONE PARAMETER FAMILY OF LINEAR DIFFERENCE EQUATIONS AND THE STABILITY PROBLEM FOR THE NUMERICAL pdf
... to the number of roots of the characteristic polynomial inside the unit circle and the number of conditions at the end of the interval of integration is equal to the number of roots outside the ... In the discrete case it essentially states that the number of initial conditions should be equal to the number of roots of the characteristic polynomial inside the unit circle and, of course, the ... necessarily to the stability of the zero solution of the same equation It is known that the well-conditioning of a linear boundary value problem, either continuous or discrete, is related to the so called...
Ngày tải lên: 23/06/2014, 00:20
Báo cáo toán học: "The Central Exponent and Asymptotic Stability of Linear Differential Algebraic Equations of Index 1" pdf
... can use the restriction of X(t, τ ) to V instead of X in the above formula) Now we will derive some properties of the central exponent of linear DAE of index and of its corresponding ODE Theorem ... C-function of im P (t) of (3.11) Thus, C-classes R of (2.1) and RUimP of the invariant subspace im P of the solution space of (3.11) coincide Suppose that xδ (t) is a solution of the perturbed ... DAE of index and the matrices A(t), B(t), A−1 , P (t) are bounded on R+ Then the central exponent Ωx of (2.1) is smaller than or equal to the central exponent Ωu of the corresponding ODE of (2.1)...
Ngày tải lên: 06/08/2014, 05:20
Báo cáo lâm nghiệp: "Production potential and ecological stability of mixed forest stands in uplands – VI. A beech/larch stand on a mesotrophic site of the Křtiny Training Forest Enterprise" pot
... related to the frequency of previous measurements Within the analysis of the hypothesis of the dependence of dieback of subdominant trees standard parameters of differences between upper and lower ... the proportion of larch slightly decreased, nevertheless, the species has taken up steadily 35% of the reduced stand area in the last 20 years On the other hand, the proportion of the second main ... At an age of 51 years, the stand with the proportion of beech and larch 80 and 20%, respectively, had the total growing stock of 430 m3/ha With the proportion of beech and larch 60 and 40%, respectively,...
Ngày tải lên: 07/08/2014, 03:22
In vitro studies on the color stability and masking ability of composite cores and the influence of posts and cores on the shades of all ceramic systems
... The translucency of composite materials is affected by such factors as the particle size and content of the filler used, the refractive indexes of the fillers and the matrix and the pigment they ... dimensional stability, radiopacity, handling properties and esthetics of the restorations One of the most important considerations in the selection of filler is the optical characteristics of the composite ... associated with the wavelengths of the light observed Chroma describes the degree or amount of 21 hue present or the intensity of the color Value is the proportion of black and white in the hue and distinguishes...
Ngày tải lên: 09/10/2015, 11:24
Cambridge.University.Press.Gender.Race.and.the.Writing.of.Empire.Public.Discourse.and.the.Boer.War.Sep.1999.pdf
... the food stocks, and the mood of the garrison The tactics of the Daily Mail captured the attention of the nation; the newspaper dramatized the situation of the town by emphasizing the danger that ... examine both the role of the press in the formation of public opinion about imperialism and the role of the press in the formation of the concept of public opinion itself Mafeking Night marks the powerful ... powerful beginning of the New Journalism at the same time as it marks the beginning of the end of the New Imperialism The coincidence of these occasions arises from the nature of the South African...
Ngày tải lên: 21/09/2012, 10:54
Cambridge.University.Press.War.and.the.Law.of.Nations.A.General.History.Sep.2005.pdf
... of individual, hand-to-hand combat Grand strategy, on the other hand, remained the preserve of Tiw.11 In India, too, much the same phenomenon was apparent in the role of Indra, the chief of the ... the mainstream of legal analysis, largely as a result of the crumbling of older conceptions of legitimacy and the rise of new aspirations for democracy and the self-determination of peoples The ... testimony both to the warlike character of the Greeks and to their feeling of cultural unity, the cities of the Amphictyonic League of Delphi agreed that, in the event of war, the combatant states...
Ngày tải lên: 21/09/2012, 11:02