hormone responsible for increasing blood glucose levels
Báo cáo khoa học: Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast docx
Ngày tải lên :
14/03/2014, 23:20
... body via the bloodstream for supply to body cells Hormones, such as insulin, control the uptake, storage and consumption of glucose in human bodies [1] The level of glucose in the human blood is ... the human blood glucose reference level (the daily lowest level before breakfast) is maintained within a range of approximately 3.9–6.1 mm [2] Glucose levels rise briefly after meals for an hour ... diabetic patients, normal regulation of blood glucose levels is disrupted for various reasons, resulting in a generally prolonged high concentration of glucose in the blood [3] The fission yeast Schizosaccharomyces...
- 17
- 271
- 0
Flavor enhancement as a tool for increasing pleasantness and intakeof a snack product among the elderly
Ngày tải lên :
03/04/2013, 21:06
... given different information on the samples for the home-use One group in both age cohorts was informed about the organic quality of the sample and another group received information about the ... presence of health-related information Since the effects of information were negligible, and not relevant enough for this study, the data were pooled together over the information conditions Home-use ... effects tested were aroma concentration of the sample (two levels) and the session (two levels, before and after the home-use) Age group (two levels) was used as a between-subject factor These statistical...
- 10
- 599
- 1
Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt
Ngày tải lên :
14/02/2014, 08:20
... Virginia: 2008 For product and ordering information: World Wide Web: http://www.usgs.gov/pubprod Telephone: 1-888-ASK-USGS For more information on the USGS the Federal source for science about ... and others (in press) Hormones Four common natural and synthetic hormones were targeted in this study Extracts selected for hormone analysis required derivatization of the hormones to facilitate ... individual samples designated for processing for agricultural pesticides, hormones, pharmaceuticals, and the YES assay The procedures used for preparing SPMD samples for analysis were similar to previously...
- 24
- 865
- 0
Tài liệu Báo cáo khoa học: Identification of two late acyltransferase genes responsible for lipid A biosynthesis in Moraxella catarrhalis doc
Ngày tải lên :
18/02/2014, 14:20
... LpxM is responsible for the addition of a secondary myristate (C14:0) chain at the 3¢-position of lipid A [36,37] In H influenzae, the htrB (lpxL) gene product was shown to be responsible for the ... were responsible for the addition of secondary laurate (C12:0) chains at the 2-position and 2¢-position of lipid A [29,38] Our results showed that the lpxX gene product in O35E was responsible for ... methanolic m HCl at 80 °C for 18 h The FAMEs were recovered into the organic phase by three-fold extraction with 50% NaCl ⁄ chloroform (1 : v ⁄ v) A new volume of chloroform was used for each of the three...
- 14
- 674
- 0
Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
Ngày tải lên :
18/02/2014, 18:20
... unequivocally inform on the orientation of the sites, only their affinity for interaction with drugs The data presented here suggest that the ABCG2R482G isoform undergoes the following sequence of conformational ... cause the conformational alteration (reviewed in [27,28]) The low-affinity conformation of drug binding sites in ABC multidrug efflux pumps is assumed to correspond to the outward-facing conformation ... the capacity for substrate interaction is considerably reduced The potency for vanadate trapping to reduce [3H]daunomycin binding to ABCG2R482G was 21.3 ± 3.3 mm of nucleotide Therefore, the data...
- 9
- 564
- 0
Tài liệu Báo cáo khoa học: Functional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase Investigations of the putative catalytic glutamate–arginine pair and of residues responsible for substrate specificity docx
Ngày tải lên :
19/02/2014, 02:20
... an almost 2000-fold decrease in the kcat value for dThd, and a 270-fold decrease for dCyd The Km value was increased sevenfold for dThd and 49-fold for dCyd The large decrease in kcat value indicates ... the catalytic rate For the E52D mutant the Km value was approximately the same as for the wild-type with dThd, whereas kcat was 20 000 times lower This was also the scenario for the E52H mutant ... and BVDU Km for AraC was increased 59-fold, but this was less pronounced than the increase of 106-fold for dCyd Vmax was fairly unchanged compared with the wild-type The Km value for BVDU was...
- 10
- 504
- 0
Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
Ngày tải lên :
19/02/2014, 16:20
... pathways for 3-hydroxyanthralinic acid differs from that in the pathway for 4-amino3-hydroxybenzoic acid The N-terminal amino acid sequence of the purified enzyme did not show significant levels ... Enlargement of the original plots shown in (B) present in cell extracts of succinate /glucose- grown cells; therefore, the synthesis of the enzyme was inducible Table shows a summary of a typical ... carboxyl group, which is a 3-ketoacid As shown in Fig 1(A), compound III in the keto form possibly releases CO2 Crawford et al and Nozaki et al have reported that protocatechuate 2,3-dioxygenase and...
- 7
- 613
- 1
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
Ngày tải lên :
22/02/2014, 04:20
... Italy (Molise region) Eight goats were used, as well as two bucks, for peripheral blood (15–30 mL), which was subsequently used for DNA extraction Casein preparation Whole casein was prepared by ... EDTA-anticoagulated peripheral blood samples, as described previously [23,24] Oligonucleotides Intronic primers used either for amplification from genomic DNA or for sequencing of amplified DNA ... buffer For genotype as1-CasM, using the amplified created restriction site (ACRS)-PCR procedure [26], experimental conditions are essentially the same as those mentioned before except for the...
- 11
- 568
- 0
Báo cáo khoa học: Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase pdf
Ngày tải lên :
07/03/2014, 00:20
... isoforms from rat (for GIRK3, the human sequence is shown) Transmembrane regions (TM1, TM2) and pore helix (P) are marked The N-terminal part that was used for G1 N-T, the region that was used for ... determinant responsible for PKA phosphorylation in vitro Previous studies had shown that the GIRK1 subunit, but not the GIRK4 subunit, isolated from bovine atrium, represented a prominent target for ... been To identify the structural determinants that are responsible for phosphorylation of GIRK1 by PKA, fusion proteins comprising truncated forms of the cytosolic parts of GIRK1 and the glutathione...
- 9
- 403
- 0
Báo cáo khoa học: Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase l isoform pdf
Ngày tải lên :
07/03/2014, 17:20
... nuclear localization for the mSMOl isoform (Fig 4) Taken together, these results consistently substantiate the hypothesis that these two structural regions are mandatory for the nuclear localization ... SDS ⁄ PAGE was performed according to the method of Laemmli [20] Expression of mSMOa, mSMOl and mSMOlD isoforms in murine neuroblastoma N18TG2 cells All experiments were performed using a pool ... neuroblastoma cell line, N18TG2, to investigate its subcellular localization Augmented transcript levels for each recombinant protein were detected in transiently transfected neuroblastoma cells, using...
- 8
- 413
- 0
Báo cáo Y học: Identification and characterization of a new gene from Variovorax paradoxus Iso1 encoding N -acyl-D-amino acid amidohydrolase responsible for D-amino acid production pdf
Ngày tải lên :
08/03/2014, 16:20
... strain Iso1 was V paradoxus For example, the stain Isol was positive for catalase, oxidase and nitrate reduction but negative of hydrolysis for gelatin and starch Therefore, according to all above ... and incubated at 37 °C overnight The transformants were screened for enzyme activity by adding to each well 10 lL mgÆmL)1 lysozyme and incubating at 37 °C for 30 This was followed by the addition ... measurements were performed at various temperatures for 20 The highest activity was taken as 100% (B) Thermostability of purified enzyme The purified enzyme was preincubation for 30 at various temperatures...
- 11
- 656
- 0
Báo cáo khoa học: The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi potx
Ngày tải lên :
14/03/2014, 22:20
... performed for days in the dark at 22 °C For large-scale DNA preparation, 250-mL Erlenmeyer flasks containing 50 mL of medium were inoculated with 108 conidia and incubated for days at 30 °C before ... conidia and incubated at 30 °C in the dark for days When indicated, the dish was illuminated under 25 WÆm)2 for different times before mycelia filtration For carotenoid analysis of the strains used ... Deutsche Forschungsgemeinschaft (DFG) (Grant AL892-1-4) We are indebted to P Beyer for valuable discussions and to D Maier and D Scherzinger for skillful technical help We are grateful to J Weidner for...
- 13
- 427
- 0
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
Ngày tải lên :
16/03/2014, 04:20
... scale) for IC50 calculation The Km for carnitine was obtained by assaying mitochondria in the presence of increasing carnitine concentrations: 50–1500 lm for pig CPTIB, and 50–2000 lm for human ... sequence as being responsible for the peculiar kinetic characteristics of this enzyme, acting as a negative determinant for malonyl-CoA sensitivity Asp17 may account, at least in part, for the high ... the single amino acid variation observed between pig and human (Asp17 for human and Glu17 for pig) might be responsible for the kinetic characteristics of both CPT1B enzymes Consequently, we...
- 9
- 550
- 0
Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
Ngày tải lên :
17/03/2014, 10:20
... 3JHNHa, and u vs w plots, Fig S2) imply a conformational preference for an extended structure The unambiguous conformational preference for helical structure for the C-terminal 10-peptide is manifested ... values for a-helix structure, while w angles for Leu14 and Arg16 are considerably close to the range of values for 310 helix Additionally, Leu14 possess a u torsion angle almost typical for the ... the short and medium range NOEs observed for the backbone and CaH protons Sequential HN–HN connectivities for stretches up to two amino acids were observed for residues 6–13, 14–19, 20–28, 29–31,...
- 11
- 515
- 0
