heart rate variability molecular mechanisms and clinical implications

... heart rate variability Cardiol Clin 1992, 10: 487-498 36 Stein PK: Assessing heart rate variability from real-world Holter reports Card Electrophysiol Rev 2002, 6:239-244 37 Malik M: Heart rate variability ... spectral analysis of heart rate variability J Hypertens 1988, 6:711-717 Mussalo H, Vanninen E, Ikaheimo R, Laitinen T, Laakso M, Lansimies E, Hartikainen J: Heart rate variability and its determinants ... of heart rate Hypertension 1993, 21: 236-247 Guzzetti S, Mezzetti S, Magatelli R, Porta A, De Angelis G, Rovelli G, Malliani A: Linear and non-linear 24 h heart rate variability in chronic heart...

Ngày tải lên: 13/08/2014, 19:20

... between change in heart rate and autonomic nervous system activity was proposed by Akselrod et al [12], who suggested that the low-frequency component of the change in heart rate reflects the ... measured the heart rate of test subjects as a time series while they were experiencing a driving simulator that combined a motion base and an immersive VR system We used the heart rate to infer ... 0.46 None Yes "Yes" including "childhood" and "occasionally" in Table (no sign and 3500-ms interval conditions) at phases 4, and 10 at p < 0.1, and 5, 6, 7, and at p < 0.05 It also revealed a significant...

Ngày tải lên: 19/06/2014, 10:20

... tsunami survivors [8] and had seven years of experience in using a polygraph to record heart rate variability and respiration (i) Autonomic and respiratory variables Heart rate variability was assessed ... them and hence were not added The absence of change in the heart rate variability may be related to the yoga program and the yoga breathing techniques in particular The breath rate and heart variability ... Society of Cardiology and the North American Society of Pacing and Electrophysiology: Heart rate variability standards of measurement, physiological interpretation and clinical use Circulation...

Ngày tải lên: 11/08/2014, 16:22

... et al 2003c) found N-RAS and K-RAS mutations, respectively, in 17% and 6% of tumors, whereas Kuehl and Shaughnessy found N-RAS and K-RAS mutations, respectively, in 14% and 17% of tumors (personal ... the following specific aims: a) Describe the landscape and clinical relevance of genomic complexity using aCGH Rationale and Hypothesis Current understanding of MM genetics is hampered by inadequacies ... accrued, we can then try to understand the molecular mechanism(s) underlying HRD MM and the potential molecular heterogeneity within HRD MM In addition, the origin and evolution of genetic abnormalities...

Ngày tải lên: 11/09/2015, 09:58

... consumption, heart rate, and heart rate variability in men Heart 2002; 88(6): 641-2 338 Ryan SM, Goldberger AL, Pincus SM, Mietus J, Lipsitz LA Gender- and age-related differences in heart rate dynamics: ... 2002; 22(5): 408-14 172 Kamath MV and Fallen EL Correction of heart rate variability signal for ectopics and missing beats In: Malik M, Camm AJ eds Heart rate variability Armonk, N.J.; Futura ... Cohen RJ Analysis of long term heart rate variability: methods, 1/f scaling and implications Comput Cardiol 1988; 14: 419-22 341 Sayers BM Analysis of heart rate variability Ergonomics 1973; 16(1):...

Ngày tải lên: 15/09/2015, 17:10

... systems for the computation and derivation of HRV, and for rejection and replacement of ectopic beats and other artifacts, may lead to variations in the HRV data generated from the same ECG recordings ... Nevrokard and F-EXTRACT HRV systems, the Bland-Altman technique (Bland JM and Altman DG, 2003, 1999) was performed using Prism 4.03 for Windows (GraphPad Software Inc., San Diego, CA, USA) The Bland-Altman ... display the Bland-Altman plots of absolute and percent differences, respectively, in the frequency-domain HRV variables, LF and HF power, normalized LF and HF power, total power and LF/HF ratio...

Ngày tải lên: 15/09/2015, 17:11

... showed the baseline foetal heart rate (fHR) as 60-70 bpm Clinical application of non-invasive foetal ECG 132 Figure 8-2: The foetal heart rate (fHR) and maternal heart rate (mHR) as displayed by ... normal and ectopic beats and thus gave an accurate measure of the true fHR The case history highlights the usefulness of non-invasive fECG in the determination of foetal heart rate and ECG and its ... intervals, and automated computation of foetal HRV parameters as well as graphical visualization of the foetal HRV power spectra Heart rate variability of healthy foetuses 153 CHAPTER 10 HEART RATE VARIABILITY...

Ngày tải lên: 15/09/2015, 17:11

... in both time and frequency domains The time domain indices measured were the mean foetal heart rate, mean RR interval, SDNN, rMSSD and pNN27 Mean heart rate is the mean foetal heart rate measured ... strip, (b) foetal and maternal heart rate traces, and (c) averaged foetal ECG complex recorded by FEMO M= maternal QRS complex; F= foetal QRS complex; Subscripts o and t = onset and termination ... ECG signal; MF’ and MF’’- 1st and 2nd derivatives containing both maternal and foetal ECG signals; F’ and F’’- Foetal ECG signals after subtraction of M from MF’ and MF’’ Materials and methods 89...

Ngày tải lên: 15/09/2015, 17:11

... HRV………………………………………………… 52 Clinical application of heart rate variability ………………………… 53 Table of Contents Chapter v Heart rate variability in the foetus………………………… 57 Development of the foetal heart rate ……………………………… ... ST segment and T wave- Animal studies……………………… 26 Foetal ST segment and T wave- Human studies……………………… 31 Chapter Heart rate variability …………………………………… 35 Definition of heart rate variability ………………………………… ... 6-5a Foetal heart rates from scalp and abdominal electrodes … …… 89 Figure 6-5b Foetal ECG complexes from scalp and abdominal electrodes … 90 Figure 6-6 Raw ECG strip, heart rates and averaged...

Ngày tải lên: 15/09/2015, 17:11

... MOLECULAR MECHANISMS AND BIOLOGICAL EFFECTS Edited by Volodymyr Lushchak and Halyna M Semchyshyn Oxidative Stress Molecular Mechanisms and Biological Effects Edited by Volodymyr Lushchak and ... Semchyshyn and Volodymyr I Lushchak Chapter Oxidative and Nitrosative Stresses: Their Role in Health and Disease in Man and Birds 47 Hillar Klandorf and Knox Van Dyke Chapter Nitric Oxide Synthase and ... and carbohydrates as compared with nucleic acids, oxidative catabolism of lipids, amino acids and Interplay Between Oxidative and Carbonyl Stresses: Molecular Mechanisms, Biological Effects and...

Ngày tải lên: 12/02/2014, 16:20

... neutral and acidic pH conditions by a variety of spectroscopic (i.e CD, fluorescence and second-derivative UV absorption) and biochemical (i.e limited proteolysis and ligand binding) techniques, and ... comparative analysis of Ngb and Mb may be used to better define the relationships between these two globins and to obtain a better understanding of the molecular features and biological function of ... ligands, both the ferrous and ferric forms of Ngb are hexacoordinated, with the proximal His64 being the endogenous ligand Therefore, Ngb ligand binding requires the displacement of the intramolecular...

Ngày tải lên: 07/03/2014, 02:20

... volume book Thus, Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences offers only an up-to-date and authoritative review of the major scientific and clinical aspects of the overlapping ... chapters Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences, edited by Christos S Mantzoros, MD is a very welcome addition to the Nutrition and Health Series and fully exemplifies ... conclusion, Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences, edited by Christos S Mantzoros, MD provides health professionals in many areas of research and practice with...

Ngày tải lên: 22/03/2014, 19:20

... segments of the heart and their respective functions in every heart cycle phase Fig 12 Diagnosable heart segments with their functions and their relations to heart cycle phases on ECG and RHEO Conclusion ... the coordinated operation of the heart and the associated blood vessels Knowing their ratios and considering the actual anatomic and functional status of the heart and the blood vessels in every ... CARDIOVASCULAR SYSTEM – PHYSIOLOGY, DIAGNOSTICS AND CLINICAL IMPLICATIONS Edited by David C Gaze The Cardiovascular System – Physiology, Diagnostics and Clinical Implications Edited by David C Gaze Published...

Ngày tải lên: 28/03/2014, 09:20

... along the way: my parents, Kay and Toshi, my teachers, and my husband, Rusty And to Mr William T Comfort, Jr., and the John A Hartford Foundation, whose kindness and interest in this project were ... age, and there are tissue-specific differences in the observed mutational rate (liver has a higher mutation rate than brain) and in the spectrum of mutations Chromosomal Instability and Aging Mechanisms ... diseases and animal models in terms of their ability to illuminate the relationship between chromosomal instability and aging II DNA DAMAGE AND REPAIR The spontaneous mutation rate is low and differs...

Ngày tải lên: 29/03/2014, 08:20

... expands these vessels [18] Surfactant is inactivated commensurately with the magnitude of tidal volume and duration of ventilation during ventilation of excised lungs [19-21] It was demonstrated ... PEEP during ventilation with a moderately increased VT *p < 0.05; **p < 0.01 vs ZEEP and the same VT Used with permission From Dreyfuss and Saumon [33] blebbing and interstitial edema [29] This ... lung injury; and 3) studies modulating hormonal and metabolic pathways: inhibition of the renin-angiotensin system [92,93] and pretreatment with atorvastatin or simvastatin [94,95] Clinical relevance...

Ngày tải lên: 21/06/2014, 01:20

... Analysis and Processing: A Comprehensive Reference, Elsevier, Oxford, UK, 2003 [18] P Novak and V Novak, “Time/frequency mapping of the heart rate, blood pressure and respiratory signals,” Medical and ... for both fc (t) and var(t) related to the three frequency bands From Figures and 8, for the case shown in Figures and 6, the optimal threshold was found to be 0.0455 Hz (for LF) and 0.003 Hz2 (for ... Time-Scale Analysis, pp 373–376, Paris, France, June 1996 [14] J P Finley and S T Nugent, Heart rate variability in infants, children and young adults,” Journal of the Autonomic Nervous System, vol 51,...

Ngày tải lên: 22/06/2014, 20:20

... segments of the heart and their respective functions in every heart cycle phase Fig 12 Diagnosable heart segments with their functions and their relations to heart cycle phases on ECG and RHEO Conclusion ... the coordinated operation of the heart and the associated blood vessels Knowing their ratios and considering the actual anatomic and functional status of the heart and the blood vessels in every ... Prx-1, SRF, and CArG element was not detected by EMSA Rather, Prx-1 enhanced both the rate of association and the rate of dissociation between SRF and CArG element, thereby increasing the rate of...

Ngày tải lên: 27/06/2014, 09:20

... Semchyshyn and Volodymyr I Lushchak Chapter Oxidative and Nitrosative Stresses: Their Role in Health and Disease in Man and Birds 47 Hillar Klandorf and Knox Van Dyke Chapter Nitric Oxide Synthase and ... and carbohydrates as compared with nucleic acids, oxidative catabolism of lipids, amino acids and Interplay Between Oxidative and Carbonyl Stresses: Molecular Mechanisms, Biological Effects and ... Oxidative and Carbonyl Stresses: Molecular Mechanisms, Biological Effects and Therapeutic Strategies of Protection 25 Fig 10 Formation of reactive carbonyls and advanced glycation and lipoxidation...

Ngày tải lên: 28/06/2014, 11:20

... the TCR transgenic K/B×N model and the situation in patients Some of the major clinical and immunological similarities and differences between CIA, the K/B×N model and G6PI-induced arthritis are ... Kamradt and Schubert Figure Arthritis scores of (᭿) DBA/1 wild-type, (᭹) DBA/1 FcγR common γ-chain deficient, and (᭡) DBA/1 FcγRIIB deficient mice Data are presented as mean clinical scores ± standard ... importantly, depletion of CD4+ cell on days 11 and 14 (i.e when clinical symptoms are at their maximum) induces rapid remission of arthritis both clinically and histologically [93] Thus, in G6PI-induced...

Ngày tải lên: 09/08/2014, 06:22

... reports No 50 and 62[13] The GTV-T and GTVN were delineated using information from the diagnostic CT and the Endoscopic Ultrasound (EUS) The clinical target volume (CTV) included the GTV-T and GTV-N ... Tissue Avoidance Table and Figure summarize the mean D5 and V40 values for the bladder, SB, and rectum IMRT planning produced significantly lower D5 and V40 values for the bladder and the SB (p < 0.05) ... Carpenter for editorial assistance, and Arantxa Zubiria y Charo Irigoyen for technical contribution Authors’ contributions JA and MM: idea and concept LA and LIR: design and development of study LIR:...

Ngày tải lên: 09/08/2014, 08:22