... splicing A variety of tools are available to us for this purpose and further investigation of these sequence variants will not only further our understanding of the splicing mechanism and improve clinical ... affect splicing and disease Clinical studies identifying aberrant splicing mutations are of great importance for genetic counselling, as a good proportion of unclassified variants are often found ... and splicing factors by molecular analysis of splicing aberrations caused by disease-causing mutations A good example of this was the mechanistic study of a deep intronic GTAA deletion in the ATM...
Ngày tải lên: 06/03/2014, 09:22
... increases cost of product so the consumers must spend more money to own products Conclusion Advertising has both good and bad points Therefore, consumers should consider whether it is good or bad before ... 0802021117 TOPIC 13 By what means can a product or a servicebe advertised? Briefly present the strengths and weaknesses of each means A product or a service can be advertised by many means such ... wide range of products to their customers because customers watch television many times a day so they can easily recognize brand name of the suppliers The customers are very impressed by the images...
Ngày tải lên: 02/06/2014, 15:10
Example of good and bad practise on board
... MARKS ACCESS/HAZARD MARKS GOOD MARKING SAFETY HARNESS SAFETY HARNESS WORKING IN HIGH PLACE WORKING IN HIGH PLACE HATCH VENTS HATCH VENTS CARGO WORK •Correct PPE, •No risk of falling, •No smoking ... VENTS HATCH VENTS CARGO WORK •Correct PPE, •No risk of falling, •No smoking on deck •No PPE, •Risk of falling, •smoking on deck WINDLASS BREAK LININGS WINDLASS BREAK LININGS WINDLASS WINDLASS PILOT...
Ngày tải lên: 11/05/2016, 22:16
Obstetrics and Gynecology Clinics of North America,by Dr. Kimberly Leslie, pdf
... characteristics and accuracy of colposcopic detection of both low- and high-grade intraepithelial lesions are similar in both pregnant and nonpregnant women [7] Examples of LSIL and HSIL in pregnancy ... sensitivity of breast cancer cells to growth factor mitogens is likely mediated by similar mechanisms, and these two classes of hormones (ie, steroid hormones and peptide growth factors) often synergize ... presence of hormone (ligand) and is regulated; however, unregulated and constitutive signaling from mitogenic pathways can mediate transcriptional activation of these receptors in the absence of steroid...
Ngày tải lên: 06/03/2014, 12:20
Obstetrics and Gynecology Clinics of North America by Dr. Aydin Arici, docx
... annually [16] By age 60, 30% of women in the United States have had a hysterectomy, and 60% of these surgeries are due to UL [17] Because UL most often affect women of reproductive age, and hysterectomy ... cytogenetic research of UL, including examination of the exact role of HMGA2 and HMGA1 in UL pathobiology, evaluation of the significance of t(12;14) and del(7q) appearing both together and independently, ... independently, identification of candidate genes on chromosomes X, 3, 10, and 13, and performance of linkage analysis on the candidate region of chromosome important in HLRCC and Reed’s syndrome in...
Ngày tải lên: 15/03/2014, 12:20
PREDICTION OF CHEMICAL REACTIVITY PARAMETERS AND PHYSICAL PROPERTIES OF ORGANIC COMPOUNDS FROM MOLECULAR STRUCTURE USING SPARC pptx
... chemical and physical properties to Program Offices (e.g., Office of Water, Office of Solid Waste and Emergency Response, Office of Prevention, Pesticides and Toxic Substances) and Regional Offices ... databases The strength of the electrostatic interaction between S and C depends on the magnitude and relative orientation of the local fields of S and C and the dielectric properties and distances through ... Agency's Office of Prevention, Pesticides and Toxic Substances (OPPTS) [1] Hence, the need for physical and chemical constants of chemical compounds has greatly accelerated both in industry and government...
Ngày tải lên: 22/03/2014, 14:20
Child Health And The Quality Of Medical Care by Sarah L. Barber University of California, Berkeley ppt
... collection of a broad array of current and retrospective socio-economic and health information among individuals, households, and communities2 The selection of households is representative of 83% of ... initial endowments, and µf is a vector of family-level and individual level constraints, µc is a set of constraints at the community-level, and z and p are the quality and price of all available ... Health Statistics median reference standard and dividing by the standard deviation of the reference distribution for a given age and gender (WHO 1993) The use of a standard growth curve establishes...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: Disruption of structural and functional integrity of a2-macroglobulin by cathepsin E pptx
... selective cleavage of a2M by cathepsin E and that the addition of Phe to the P¢3 site causes a loss of this selective action of cathepsin E In agreement with these results, the Fig Effects of synthetic ... action of a2M on these aspartic proteinases, the effect of lowering the pH below 5.5 on the association of a2M with cathepsins E and D and the structural change in a2M upon complex formation with these ... related to those of these species (Fig 5) Although the overall sequence of this region of bovine a2M was significantly similar to those of human, mouse, and rat sources (59%, 62%, and 55% identities,...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo khoa học: PKCd-dependent cleavage and nuclear translocation of annexin A1 by phorbol 12-myristate 13-acetate pdf
... fractions of treated and untreated cells These results indicate that accumulation of ANX-1 in the nucleus is a result of translocation of the cleaved ANX-1 to the nucleus We next examined dose- and ... of ANX-1 [12] However, it is not clear which isoform of PKC mediates the cleavage of ANX-1 PKCd is a member of the novel PKC subfamily and is known to play a critical role in the regulation of ... are representatives of the cells observed in three independent experiments nuclear translocation of ANX-1 were not inhibited by the addition of these inhibitors suggesting that these molecules are...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo khoa học: Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome ppt
... Analysis of complementation of Dnop53 ⁄ GAL::A-NOP53 by truncated mutants of Nop53p (A) Analysis of complementation of strain Dnop53 ⁄ GAL::A-NOP53 by truncated Nop53p mutants, under the control of ... 27S and 7S [13–16] The exosome is also involved in processing of snoRNAs and degradation of defective rRNAs and cytoplasmic mRNAs [17,18] These results indicate that the exosome has two types of ... recovery of TAP-purified complexes was analyzed by the detection of other subunits of the exosome and box C ⁄ D snoRNP by western blotting (Fig 7B) TAP–Nop58p co-purified endogenous Nop1p and TAP–Rrp43p...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo hóa học: " Surface Modification and Planar Defects of Calcium Carbonates by Magnetic Water Treatment" pptx
... on the lowfrequency side of the 875 and 711 cm-1 band indicates a minor amount of aragonite that has characteristic doublet bands in such frequencies [18] The broad band of magnetite at 595 cm-1 ... in terms of supercooling and oversaturation of ions under the influence of H2O and magnetohydrodynamic forces was likely not large in the present dynamic growth of calcite, aragonite, and magnetite ... center, 0.2 s/cycle, and with an electric ground to the Earth (B1g and A1g), and 1084 (m1 symmetric stretching mode of CO2-) according to the assignment of ref [20] The bands at 145 (translational...
Ngày tải lên: 21/06/2014, 08:20
Báo cáo nghiên cứu khoa học: "ESTIMATION OF SCAVENGING ACTIVITY OF PHENOLIC COMPOUNDS BY CALCULATING SPIN DENSITY DISTRIBUTION" ppsx
... in principle be obtained by analysis of the 13C and 17O isotropic or anisotropic hyperfine couplings, but these have not been reported presumably because of difficulty of detection Without such ... E and other phenols can react with DPPH• (2, 2-diphenyl-1-picrylhydrazil radical) and other electron deficient radicals (ROO•) by two different and nonexclusive mechanisms, H-atom transfer and ... in polyphenolic compounds is largely influenced by the neighboring groups and by the geometry, which are performed by the conjugation systems and electron delocalization That could be easily...
Ngày tải lên: 22/07/2014, 06:20
Báo cáo y học: "Higher susceptibility to Fas ligand induced apoptosis and altered α modulation of cell death by tumor necrosis factor-α in periarticular tenocytes from patients with knee joint osteoarthritis" ppt
... cell death Of note, apoptosis of fibroblast-like cells is regulated at a number of different levels, and there is evidence that secondary modulation of signalling pathways downstream of Fas may ... Borenstein D, Brandt K, Christy W, Cooke TD, Greenwald R, Hochberg M, et al.: Development of criteria for the classification and reporting of osteoarthritis Classification of osteoarthritis of the knee ... (CD-95/Apo-1) and the p55 tumour necrosis factor (TNF) receptor I (TNFRI) are prominent examples of such receptors The mechanisms through which stimulation of Fas by the Fas ligand (FasL) initiates...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Temporal and spatial patterning of an organ by a single transcription factor" pps
... algorithm The results of these analyses were a set of sequence motifs that were found to be overrepresented in promoters of particular subgroups of pharyngeal genes (Figure 1) But are these motifs actually ... were identified, and sitedirected mutagenesis of the element was used to evaluate whether loss of function led to loss of the temporal pattern of expression The native context of the identified ... completed genome sequence of the related nematode Caenorhabditis briggsae [10,11]; conservation of sequences between the genomes of C elegans and the closely related C briggsae is often used to make...
Ngày tải lên: 14/08/2014, 14:21
Common and chemical names of herbicides approved by the weed science society of america
... 56:896–903 Common and Chemical Names of Herbicides Approved by the Weed Science Society of America Below is the complete list of all common and chemical names of herbicides approved by the Weed Science ... Keese, R Parker, D E Riechers, T W Miller (ex-off), F Tardif (ex-off) Common and Chemical Names of Herbicides Approved by the Weed Science Society of America Common Name Chemical Name acetochlor ... lieu of the selections printed previously on the back cover of Weed Science Only common and chemical names included in this complete list should be used in WSSA publications In the absence of a...
Ngày tải lên: 04/09/2015, 07:23
Identification of novel cytosolic binding partners of the neural cell adhesion molecule NCAM and functional analysis of these interactions
... of the samples and standard dilutions were pipetted in triplicates into wells of a 96-well microtiter plate and incubated with 25 àl of a mixture of solution S and A (ratio 1:50) and 200 àl of ... results 66 Investigation of the interaction of NCAM and KLC1 67 Confirmation of the interaction of NCAM and KLC1 by co-IP 67 Interaction domains of NCAM and KLC1 67 Co-localization ... Table of content 4.1.3 4.2 III Detection and identification of potential interaction partners of hNCAM180ID and hNCAM140ID by protein macroarray 44 Verification of the interaction of NCAM...
Ngày tải lên: 25/11/2015, 13:27
single crystal growth and magnetic properties of rrhin5 compounds
... experiments and energy band calculations 2.4 MAGNETIC PROPERTIES OF RIN3 AND RRHIN5 COMPOUNDS 2.4 27 Magnetic properties of RIn3 and RRhIn5 compounds 1) RIn3 compounds Rare earth intermetallic compounds ... The detected topology of the Fermi surface is found to be the same as that of LaRhIn5 , consiting of two kinds of corrugated cylindrial (bands 14 and band 15) Fermi surfaces and a lattice-like Fermi ... Abstract A series of ternary compounds RRhIn5 (R: rare earths) was grown in the single crystalline form by means of the flux method Magnetic properties of these compounds were investigated by measuring...
Ngày tải lên: 14/01/2016, 13:46
Research on the correlation between forest management and climate change in bao thang district, lao cai province local peoples perception and potential uses of GIS technology
... investigating alternative futures of land use and land cover and the potential impacts of Earth systems Land use and land cover change is now recognized as a major force of environmental change It affects ... change and anthropogenic activities Land use and land cover change affects a wide range of human and natural systems and contributes to changes in carbon exchange and climate through a range of feedbacks ... availability of water, in combination with unsustainable land use practices and expansion of industrial zones Provision of forest ecosystem services and goods will be altered by these changes,...
Ngày tải lên: 28/04/2016, 13:42
An investigation into the syntactic features and the uses of english and vietnamese negative sentences in some contexts (1)
... features of NSs in E and V? What are the uses of NSs in E and V? What are the similarities and differences of NSs in E and V in terms of the syntactic features and the uses? 1.4 ORGANIZATION OF THE ... English and Vietnamese 4.3 THE SIMILARITIES AND DIFFERENCES OF E AND V NSs IN TERMS OF THE SFs AND THE USES 4.3.1 Similarities and differences of SFs in E and V NSs 4.3.1 Negative statements a Similarities: ... features and the uses of negative sentences in English and Vietnamese in some contexts 3.2 RESEARCH DESIGN AND METHODOLOGY Descriptive research and comparative analysis 3.3 DATA COLLECTION AND ANALYSIS...
Ngày tải lên: 14/05/2016, 18:40