genetic predisposition to coronary heart disease
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... Packard CJ, Ehrenborg E. Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men. J Int ... Conclusions To address the question whether the +T294C polymorphism in PPARδ is associated with the risk for coronary heart disease and/or plasma lipid levels in women, we investigated this genetic ... CM, Gotto AM, Marian AJ. Effects of PPARα, γ and δ haplotypes on plasma levels of lipids and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary...
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coronary heart disease - clin., pathol., imaging, molec. profiles - z. vlodaver, et. al., (springer, 2012)
... GarryEditors Coronary Heart Disease Clinical, Pathological, Imaging, and Molecular Profiles 151 Anatomy of Coronary Vesselsseptum is supplied by branches arising from both the right coronary ... the heart tube to contribute to the connective tissue of the myocardium and epicardium and give rise to the coronary arteries [ 6, 7 ] . Chapter 2 Cardiac Development and Congenital Heart Disease ... second heart field onto the outflow tract. This process is regulated by global cardiac transcription factors including Nkx2-5 , Gata4 , and transcription factors specific to the second heart...
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báo cáo hóa học:" Structural ambiguity of the Chinese version of the hospital anxiety and depression scale in patients with coronary heart disease" doc
... exploratory factor analysis should beused to determine the original factor structure of aninstrument, and confirmatory factor analysis used to determine how well an a priori-defined factor structurefits ... literature to see exploratoryfactor analysis used to investigate the factor structure of aninstrument that has previously been investigated usingexploratory factor analysis. Consequently, exploratory ... (HADS) is a widely used screening tooldesigned as a case detector for clinically relevant anxiety and depression. Recent studies of theHADS in coronary heart disease (CHD) patients in European...
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báo cáo hóa học:" Comparison of the SF-6D and the EQ-5D in patients with coronary heart disease" pdf
... completed prior to intervention and 1, 3, 6 and 12months post-intervention in a study enrolling 561 patients with symptomatic coronary stenosis.Patients were randomized to off-pump coronary artery ... the OctoStent off-pump CABG group; changes in the Octopump groups are comparable to this group and therefore omitted from the tableHistogram of baseline EQ-5D and SF-6D scoresFigure 2Histogram ... symptomatic coronary sten-osis.MethodsWe included patients with symptomatic coronary stenosisenrolled in two multicenter randomized controlled trialsassessing the efficacy of the Octopus...
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báo cáo hóa học:" Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease" pptx
... patients have roughly correspond to their dis-ease severity, so it was important to take the disease stageinto account when trying to map from disease specificvariables to the EQ-5D index.Several ... Mapping models may need to be derived sepa-rately for different disease groups, since the most effec-tive predictors may vary between diseases. Also, mappingmodels need to incorporate variables ... groups, including those with coronary heart disease. Studies often require patients to complete many questionnaires and the EQ-5D may not be gathered. This study aimed to assess whether demographic...
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N-Terminal Pro–B-Type Natriuretic Peptide and Long-Term Mortality in Stable Coronary Heart Disease ppt
... associated with coronary heart disease. 9,10 However, unlike previous investigators, we used an-giographically diagnosed coronary artery disease to define existing coronary heart disease. Patients ... mortality in stable coronary disease 671 end-diastolic pressure, and were more likely to havea history of myocardial infarction, clinically signifi-cant coronary artery disease, and diabetes; ... findings (%) <0.001No coronary artery disease 31 19 14 161-Vessel disease 28 21 13 182-Vessel disease 19 24 23 193-Vessel disease 15 26 40 36Left main coronary artery disease 7 10 10 11LVEF...
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Low-Carbohydrate-Diet Score and the Risk of Coronary Heart Disease in Women potx
... (<22.0, 22.0 to 22.9, 23.0 to 23.9, 24.0 to 24.9, 25.0 to 27.9, 28.0 to 29.9, 30.0 to 31.9, 32.0 to 33.9, 34.0 to 39.9, or ≥40.0), smoking status (never, past, or current [1 to 14, 15 to 24, or ... risk of coro-nary heart disease must take each macronutrient into consideration. Different types of fat appear to have different effects on the risk of coronary heart disease. In epidemiologic ... the U.S. Postal Service.21 Fatal coronary heart disease was con-firmed by an examination of autopsy or hospital records, by a listing of coronary heart disease as the cause of death on the...
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Inflammatory Markers and the Risk of Coronary Heart Disease in Men and Women doc
... Inflammatory Markers and the Risk of Coronary Heart Disease in Men and Women n engl j med 351;25 www.nejm.org december 16, 2004inflammatory markers and the risk of coronary heart disease ... the roleof inflammatory markers in coronary heart disease, we used an etiologic approach in our main analyses, to take into account the pathophysiology of coro-nary heart disease and include ... www.nejm.org december 16, 2004 inflammatory markers and the risk of coronary heart disease in men and women 2607 the risk of coronary heart disease and that the riskswere attenuated...
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human genome epidemiology 2nd edition building the evidence for using genetic information to improve health and prevent disease jan 2010
... Medical genetics—Methodology. 3. Genomics. I. Khoury, Muin J. [DNLM: 1. Genetics, Medical—methods. 2. Genetic Diseases, Inborn—epidemiology. 3. Genetic Predisposition to Disease epidemiology. 4. Genetic ... point that is central to the search for moderate- to high-frequency low- penetrance variants associated with human diseases and traits (12). Efforts to replicate are necessary to guard against the ... data to validate gene discoveries for clinical and population-level applications, especially given the modest associations between genetic factors and disease burden; (c) commitments to evidence-based...
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