gene expression of carotenoid oxygenases in adult vertebrates

... its regulators? ?gene- encoding metalloproteases (MMPs) Additionally, we extended our study by analyzing liver expression of genes encoding IGF-1, IGF-1R, and proteins involved in inflammatory and ... reason, herein, we examine hepatic histology and expression of genes encoding proteins of the cytoskeleton, extracellular matrix, and cell-cell molecules and inflammation-related proteins A partial ... relative mRNA expression levels of the genes of interest were normalized to Tbp expression using the simplified comparative threshold cycle delta, cycle threshold (CT) method [2−(ΔCT gene of interest−ΔCT

Ngày tải lên: 04/12/2022, 14:52

... cells In higher plants, the regulation of carotenoid biosynthesis has mainly been investigated in the context of seedling de-etiolation and the accompanying burst in carotenoid biosynthesis Lintig ... accumulation of carotenoids in D salina cells Wang et al [44] reported that irradiation of H pluvialis at 350 μmol m−2 s−1 induced an increase in carotenoids, and that the astaxanthinaccumulating red ... the expression of the GGPP synthase gene (ggps) in Sinapsis alba seedlings remained constant during deetiolation This report is consistent with our data showing that EgcrtE expression remained

Ngày tải lên: 26/05/2020, 20:40

... japonicus) gene encoding riboflavin-binding protein (RfBP) This protein contains a nitroxyl-terminal ligand-binding domain, which is implicated in molecular interactions, and a carboxyl-terminal phosphorylation ... Open Access Expression of turtle riboflavin-binding protein represses mitochondrial electron transport gene expression and promotes flowering in Arabidopsis Liang Li†, Li Hu†, Li-Ping Han, Hongtao ... RfBP-induced early flowering also correlates with increased expression of FD and AP1 at the shoot apex [40], suggesting the role of RfBP in concurrently enhancing the expression of flowering-related

Ngày tải lên: 26/05/2020, 23:27

... also suggesting its importance during insect infection Genes involved in intracellular metabolism Induction of different metabolism genes in Photorhabdus and Xenorhabdus during insect infection ... uncharacterized genes (Class VII) Genes involved in metabolism constitute about 25% to 33% of the total number of in vivoinduced genes (Fig 3), showing large numbers of metabolic changes during insect infection ... found in several bacterial pathogens including P luminescens, Yersinia and Xenorhabdus [34] Interestingly, Tca toxin encoding genes were also found to be induced in a related species P luminescens

Ngày tải lên: 01/11/2022, 09:06

... Journal of Neuroinflammation (2015) 12:6 DOI 10.1186/s12974-014-0221-4 RESEARCH JOURNAL OF NEUROINFLAMMATION Open Access Differences in the distribution, phenotype and gene expression of subretinal ... found in the subretinal space in both mice and humans Our goal was to study the spatial and temporal distribution, the phenotype, and gene expression of subretinal MG/MΦ in mice with normal retinas ... retinal degeneration), and documented their fundus appearance and the change with aging Immunostaining of retinal pigment epithelium (RPE) flat mounts was done for 1) Ionized calcium binding

Ngày tải lên: 01/11/2022, 09:49

... http://www.nutritionandmetabolism.com/content/7/1/75 Page of 11 Figure The gene expression of BDNF and TrkB in the hippocampal tissue of ovariectomized rats The gene expression of BDNF and TrkB in the hippocampal tissue of ovariectomized ... decline in Alzheimer’s disease [33] PSD-95 and spinophilin belongs to postsynaptic proteins involved in synapse stabilization and plasticity [34] It is suspected that increased expression of genes ... M/1910/4), containing 152 mg/g daidzein, 80 mg/g glycitein and 35 mg/g genistein Page of 11 Table The composition of the control diet based on the formula of AIN-93G purified diet Ingredient Concentration

Ngày tải lên: 02/11/2022, 09:25

... electrogenetic device consists of the region encompassing the gene coding for the SoxR protein and the divergent overlapping PsoxR/PsoxS promoters A gene of interest is placed downstream of the ... redox-cycling drugs32,38,39), SoxR activates transcription of the SoxS protein from the PsoxS promoter The SoxS protein, in turn, regulates dozens of other genes, mainly with the aim of detoxifying ... the indicated charges Left panel indicates graphic representation of charge (area of shaded blue) increasing with application length of time of oxidizing potential ( ỵ 0.5 V) (e) Overlay of cell

Ngày tải lên: 24/11/2022, 17:42

... evidence of increased circulating levels and salivary gland expression of IL- 18 in SS, suggesting an important contribution of this cytokine to the modulation of immune inflammatory pathways in this ... cytokine a prime candidate also in the pathogenesis of SS. Increased serum levels and salivary gland expression of IL- 18 in patients with SS is in keeping with an active role for this cytokine in ... become uncoupled from or independent of the level of cellular infiltration. In addition, the demonstra- tion of increased ductal expression of IL-18 in SS would be in keeping with other autoimmune

Ngày tải lên: 09/08/2014, 01:23

... and ED-A FN in dcSSc skinIncreased expression of LOX and ED-A FN in dcSSc skin. Cryosec- tions of (a,b) normal skin are compared with (c-f) dcSSc skin. In normal skin, immunostaining for LOX ... four-fold eleva- tion of creatinine kinase accompanied by the clinical finding of proximal weakness defined muscular involvement, whilst renal involvement was determined by history of scleroderma renal ... immunostaining was detected in the keratinocyte layers of the epidermis [38]. In all samples of dcSSc skin, there was a pronounced increase in Thy-1 staining throughout the dermis (Fig. 4c). In perivascular

Ngày tải lên: 09/08/2014, 07:20

... protein coating. In fact, both protein coatings induced a further downregulation of collagen II expression by about 50% or more at most passage time points. Interestingly, even the no coating ... integrins can attach to region 1 (for example the I-domain of integrin α 2) of collagen I surfaces with a similar homology to the von Willebrand factor [40]. In addition, integrins also aid in ... I gene expression profiles of meniscal fibrochondrocytesCollagen I gene expression profiles of meniscal fibrochondrocytes. The x-axis refers to the passage number, and the y-axis to the gene expression

Ngày tải lên: 09/08/2014, 10:21

... proteins of the [Fe-S] cluster biosynthesis pathway, i.e. altering the expression of cysteine desulfurase genes. Stress dependent changes in gene expression occur in the cytoplasm a s well as in ... levels in leaves. In silico analysis of promoter regions indicated the presence of different cis-elements in cysteine desulfurase gene s, in good agreement with differential expression of each ... are involved in sensing environmental stimuli and regulation of protein expression [1-3]. In plants, the biogenesis of Fe-S proteins is compartmentalized and mostly adapted to the requirements of

Ngày tải lên: 11/08/2014, 11:21

... analysis of 48 tissues and organs at various stages of growth and by continuous gene expression profiling of leaves at weekly intervals from transplanting until harvesting Our gene expression profiling ... overexpression of AtHAP2 delays flowering via down-regulation of FT [34] In SD-flowering rice plants, the CCT-domain containing proteins Hd1 and Ghd7 regulate flowering by repressing expression of ... processes involved in expression of agronomic traits that determine crop yield Taken together, a field transcriptome obtained by a wide range of gene expression profiling provided not only baseline information

Ngày tải lên: 11/08/2014, 11:21

... represents a terminal destination Hypothesizing that DC and rAM residing in different... interleukins and interleukin receptors Integrins are key mediators of cell- cell interactions, ... paid to genes involved in cell traf- ficking, namely integrins, metallopeptidases, chemokines and chemokine receptors, as well as interleukins and interleukin receptors (Table 1). In order to visualize ... chemokine and chemokine receptor expression, confirming and expanding previous reports. The expres- sion profile of lung DC was essentially similar to the Validation of chemokine and interleukin genes

Ngày tải lên: 12/08/2014, 14:20

... nificant increase in the numbers of WBC at calving. This was mainly due to an increase in the numbers of circulating neutrophils, and to a less extent, an increase in monocytes. At calv- ing, the ... Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, 3 Department of Chemistry, National Veterinary Institute (SVA), Uppsala, Sweden. Introduction ... (Becton Dickinson Vacutainer Systems, Meylan, France), one month before estimated calving, at calving (within 24 hours after calv- ing) and one month after calving. Before sam- pling, the skin was

Ngày tải lên: 12/08/2014, 15:20

... inflammatory cytokines and chemokines in the lung has been given increasing attention and a variety of cytokines and chemokines are considered to play impor- tant roles in the pathogenesis of lung inflammatory ... sug- gest that coculturing of lung epithelial cells with MT-2 resulted in infection with HTLV-I. Induction of expression of cytokines, chemokines and cell adhesion molecule in A549 cells cocultured ... the production of inflammatory cytokines and chemokines, and the expression of cell adhesion mol- ecules by the infected cells. Such process may be involved in the pathogenesis of HTLV-I-related

Ngày tải lên: 13/08/2014, 05:21

... maintenance of surfactant protein expression in adult human ATII cells in monolayer culture has been difficult Recently, we developed a system for maintaining the differentiated functions of adult ... done with adult human ATII cells cultured with d of TGFa and d of KGF Similar findings were observed in ATII cells cultured in KGF (K) alone, in d of K and d of KD (data not shown) or in d of KIA ... production of mature SP-B Napsin A and pepsinogen C, asparatic proteases, are also involved in the processing of proSP-B [53,63] We found no changes in the protein levels of napsin A or pepsinogen...

Ngày tải lên: 12/08/2014, 11:23

... containing DNA spots (5 lg each) corresponding to internal fragments of ADC or cruzipain genes The latter (used as a control) is a housekeeping gene that encodes the main cysteine proteinase of ... a-amanitin of the transcription of arginine decarboxylase (ADC) and cruzipain genes in transformed Trypanosoma cruzi Permeable parasites were preincubated at °C for in the absence or presence of different ... chromosomal integration [19] After 48 h of transfection, geneticin (G418) was added to the cultures of transformed parasites to select plasmidcontaining protozoa The time course of ADC gene expression...

Ngày tải lên: 19/02/2014, 07:20

... induces the expression of several genes, such as those for GK, phosphofructokinase, phosphoglycerate mutase Activation of expression of fbaA in Synechocystis and PK, including sll1330 [34] In this ... respect to the accumulation of inhibitory metabolites [27,28] and gene expression [29] The expression of 10% of the genes was different in the linear growth phase compared to in the logarithmic growth ... assembly of photosynthetic machinery proteins [32] The SodB protein (Spot 29) catalyzes the dismutation of O2) to H2O2 and O2, in which sodB gene and SodB protein expression are induced by continuous...

Ngày tải lên: 16/03/2014, 04:20

... mechanisms involved in the increase or maintenance of bone mass in OA This study of the IT region of the proximal femur in primary hip OA and non-OA postmortem controls investigated changes in gene expression ... level of COL1A2 mRNA, the corresponding level of COL1A1 mRNA was greater in OA samples Per unit of COL1A2 gene expression, the level of COL1A1 gene expression in OA was almost double that in the ... joint cartilage degeneration supports the concept of generalised involvement of bone in the pathogenesis of OA 10 11 12 13 14 Competing interests The authors declare that they have no competing...

Ngày tải lên: 09/08/2014, 08:23

... rendering them active [16] Several lines of evidence point to the involvement of the mitochondrion and the Bcl-family of proteins in the induction of lymphocyte apoptosis during sepsis Overexpression ... leucocytes in sepsis patients and caspase-8 is active [22] in severe sepsis in animals Inhibition of Fas or silencing of caspase-8 inhibits apoptosis during sepsis [9] Interestingly, cross-talk of Fas-receptor ... Figure Expression of Bcl-2 severe sepsis Expression of Bcl-2 inin severe sepsis The expression of the Bcl-2 protein was measured by flow cytometry in CD4+, CD8+ and CD19+ lymphocytes In CD4+...

Ngày tải lên: 13/08/2014, 11:23