gastrointestinal and liver changes in the elderly1

... and periphery of the Seto Inland Sea The location of the research area and the distribution of the citrus groves in Matsuyama region are shown in Fig Matsuyama is situated in Shikoku Island in ... 66m, and 60m, respectively Stream water samples were collected at the middle parts of the grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the ... in the other stream The two streams flow together to be one stream and the sampling point St.4 is situated in the joined stream, which is the only stream that flows into the reservoir The reservoir...

Ngày tải lên: 05/09/2013, 10:17

... in the TSLN Both of these effects would appear to be advantageous towards inducing better tumor immunity and protecting against the spread of tumor cells into the draining TSLN While most of the ... stores and breakdown of body fat supporting another indication for the inclusion of RU486 in therapy Thus, the use of RU486 in prostate cancer therapy could have effects on cachexia, androgen-dependent ... on the use of an Ad5IL-12 vector in experimental cancer therapy including prostate cancer with promising results including the ability to aide in the suppression of lung metastases [40,41] The...

Ngày tải lên: 18/06/2014, 16:20

... respectively)) and the dry mass of the main stem (DMshoot) at the end of the experiment, the dry mass of the main stem at the start of the experiment and after 50 days was estimated using the following ... Z2 for RHG and RGDS in the second part of the growing period as well as in the total period indicates that the difference between the control and the shade treatments in height growth and stem ... of the growing period, e.g RDG and RGDS were reduced by the nets even in the first part of the growing period (table II, figure 3b and 3c) The significant interaction between the variables Z1 and...

Ngày tải lên: 08/08/2014, 01:21

... 0.1% Chaps and 150 mM NaCl and protease inhibitors [5 lgÆmL)1 pepstatin A, lgÆmL)1 aprotinin, and mM phenylmethanesulfonyl fluoride]) and lysed by three cycles of freezing and thawing in liquid ... isolog H and L The L isolog is ubiquitously expressed in all the tissues whereas the H isolog is detected in the heart and skeletal muscle tissues [3] The Northern blot in Fig 1E shows that in both ... carried out initially at 100 V until the protein samples were within the stacking gel, and then at a constant current of 18 mA (500 V) for 5–6 h The proteins were transblotted onto a poly(vinylidene...

Ngày tải lên: 20/02/2014, 23:20

... times were 2–5 The conformational changes induced in HDC by histidine and histidine-analogs involve alterations in the environment of the aromatic amino acid residues of the protein Fig Thermal denaturation ... how long the enamine remains in the active site and its rate of attack on the aldimine bond, and can be modified by slight differences in the position of the residues [41] As covalent binding was ... spectra Summarizing, data shown in Fig reinforce our previous findings on the tautomeric forms of the internal aldimine in the free holoenzyme [19] and the reaction carried out with the suicide analog...

Ngày tải lên: 08/03/2014, 08:20

... pits and in the neck of the gastric glands Aldh1 expression continued in duodenum with the signal confined to the epithelial cells of the villi, whereas the lamina propria showed no expression In ... corresponding rat tissues show expression only in duodenum, colon and rectum In both mouse and rat, Adh4 is found in the epithelial lining of upper GI tract including the tongue, esophagus and stomach, ... corresponding sections at the same magnification High levels of Adh1 mRNA are observed in the epithelial cells at the base of the intestinal glands in rectum and moderate levels of Adh4 are present in the...

Ngày tải lên: 16/03/2014, 11:20

... structural changes in the flaps near the mutated Ile46, and in the interactions of the mutated Thr82 and Val84 with indinavir [18] Local changes in the mutated residues were also observed in the crystal ... local and more distal changes propagating to the inhibitorbinding site Fig Structural variation in residues 81–82 near indinavir Stereoview showing the benzyl group of indinavir interacting with ... 51¢)54¢ in PR relative to the values in the two mutants Ile50¢ was ordered in all three structures and the side chain fitted well in the S2 binding pocket created by the t-butyl group of indinavir...

Ngày tải lên: 23/03/2014, 12:20

... during walking are quite different from those involved in maintaining upright posture During standing, the goal is to maintain the body's center of gravity (CG) within the base of support The initiation ... Hz The smoothed coordinates then became inputs to the standard link-segment model ing during walking These variables are presented in the Table Results and Discussion In addition to the joint ... mechanisms behind the observed changes With this background in mind, there is a need to document the motor pattern changes that occur in the gait of the elderly and to determine whether those changes...

Ngày tải lên: 28/03/2014, 19:21

... change is coordinated through a common movement with the AC subdomain during the closing of the subdomains However, the flexible linker between the AC subdomain and the PCP domain, and the absence ... between the two subdomains of the A domain These findings were later explained with the structural model that the smaller subdomain AC of the A domain rotates upon substrate binding and changes ... domain and also with the idea that binding of the PCP to the A domain in a productive manner increases the compactness of the protein Further control reactions with a noncognate inhibitor of the...

Ngày tải lên: 29/03/2014, 08:20

... signing, and a questionnaire containing self-reports such as the SPAQ, the 15D, the GHQ-12 and the Beck Depression Inventory (BDI) that interviewees were asked to fill in and bring along to the ... that both the seasonal changes in mood and behavior and the experienced illumination indoors contributed independently to the HRQoL, since both the GSS (t = -13.34, P < 0.001) and the illumination ... both the seasonal changes in mood and behavior and the experienced illumination indoors contributed independently to mental well-being, since both the GSS (t = 12.63, P < 0.001) and the illumination...

Ngày tải lên: 18/06/2014, 19:20

... pressure influencing the landscape structures in the vicinity of the linear construction in the form of a motorway, and especially due to the accompanying structures of linear or polygon character and ... monitor changes in the landscape structures and various approaches to their management in the vicinity of the motorway These images were compiled into a time series depicting development of the landscape’s ... will increase (Meeus 1993) When looking at the accelerating biological and cultural degradation of landscapes, there is a need for better understanding of the mutual interaction between the landscape...

Ngày tải lên: 07/08/2014, 10:21

... the new demands exerted by the dramatic decrease in intestinal Gastrointestinal argyrophil cells in ovariectomized osteoporotic rats 187 Fig Number of argyrophil cells in GI tract and their changes ... situated in the intestinal regions In addition, the endocrine cells are regarded as the anatomical units responsible for the production of gut hormones, and a change in their density would reflect the ... ovariectomy and/ or sham-operation after 18hrs fasting to GI empty Collected samples fixed in Bouins solution, then embedded in paraffin, sectioned (3~4 µm) and stained with hematoxylin-eosin stain for...

Ngày tải lên: 07/08/2014, 17:23

... enircodne cinoloC L suilemirG ,R gnilnetS ,A nossleinaD ,M yhlaS-lE 943-143 ,772 ,4991 seR eussiT lleC ,gorf neerg eht fo tcart yratnemila eht fo sllec enircodne eht ni B dna A ninargomorhc ... nI stluseR 962 giF ecnereffid tnacifingis a deredisnoc saw 50.0 naht ssel fo eulav-p a dna )ASU ,SSPS ;3.1.6 esaeleR( swodniW rof SSPS htiw atad fo ecnacifingis eht ezylana ot desu saw )tset ... dezimotceiravo eht ni detroper erew sllec lihporygra IG fo esaerced yltnacifingis a ,noitidda nI ]62[ aimena suoicinrep dna ,]3[ aimenirtsagrepyh ,]1[ sitirtsag cihporta ,]7[ esaesid s’nhorC...

Ngày tải lên: 07/08/2014, 18:21

... mechanisms involved in the increase or maintenance of bone mass in OA This study of the IT region of the proximal femur in primary hip OA and non-OA postmortem controls investigated changes in gene ... to be narrower and aligned in a disorganised manner, which may contribute to the under-mineralisation in OA [8] Interestingly, the findings of the present study indicated that the ratio of COL1A1/COL1A2 ... produced by the various bone marrow and bone cell types in the bone microenvironment [42,43] The role of these growth factors suggests their involvement in the preservation of the bone matrix The two...

Ngày tải lên: 09/08/2014, 08:23

... wrote the first draft of the manuscript JJ, JC and JMA contributed to the final version of the manuscript GA, RB-D and AR helped in the data analysis and interpretation JJ and JC supervised the ... significant changes in the pattern of chemokine gene expression in circulating leukocytes The data suggest that PPARα activators may be useful in the attempt to decrease the risk of atherosclerosis and ... levels and a similar effect in the contiguous endothelial cells, which, in combination with the CCR2 decreased expression, could be beneficial with respect to the risk of atherosclerosis considering...

Ngày tải lên: 10/08/2014, 05:21

... neurons innervating urinary bladder but there was no change in neurons innervating the colon Inferences from the present results point to lesioninduced intrinsic changes in the peripheral axons and ... assisted in data analysis and revising the manuscript AW assisted in interpreting the data and in writing and revising the manuscript All authors read and approve the final manuscript Acknowledgements ... generated by delivering stimuli (1 ms duration), which were increased in steps (in Volts) starting from 0.05, and then increasing from 0.1, to 1.0, and from to 10, in 0.1 V and V increments, respectively...

Ngày tải lên: 10/08/2014, 10:20

... treatment, including physiotherapy and NSAID administration, was initiated in another clinic, the pain in his ankle progressively worsened and he demonstrated gait disturbance A physical examination ... events Although treatment, including physiotherapy and NSAID administration, was initiated in another clinic, the pain and swelling of his right foot progressively worsened, and he demonstrated gait ... decreased pain and regional osteoporotic findings in the foot or ankle Also, since the discontinuation of the bisphosphonate treatment, our patients have not complained of bone pain, and normal...

Ngày tải lên: 10/08/2014, 23:22

... much higher in the crown tissue of the two winter varieties than in Paragon and increased across the time course There was also an increase in transcript abundance in leaf tissue of the winter varieties, ... of TaAGL42 increased, principally in leaf tissue, in the winter varieties and showed no response in Paragon If these two MADS-box genes are involved in cold induced phase transition, their profiles ... occur during the winter in a northern climate – a gradual decline in temperature, day-length and light intensity In most previous studies, unnaturally high light intensities have been maintained...

Ngày tải lên: 12/08/2014, 03:20

... sequences in other sites of the gene intensively binding TBPs indicate that TBP binding is not dependent on the presence of MAR TBP binding and transcription The overall intensity of the DNA association ... along the genes and transcription factor binding modules were revealed Comparison of the predicted MAR with the TBP binding sites in the Bmy1 gene Intron indicates that this site is enriched in ... imbibition These results indicate an increase in the number of the tight interaction sites between TBPs and DNA In contrast, the loci Bmag0382, GBMS0184 and WMCIE8 of 1H and AF022725A, cMWG 728 and...

Ngày tải lên: 12/08/2014, 03:20

... and the maximum diameter of the largest follicle during the period before ram introduction are presented in Table After introduction of the rams, the diameter of the largest follicle and the ... while the LH surge in only 11 ewes may be explained by the sampling regime (each 12 h), missing the remaining surges between two consecutive bleedings The lack of differences between stimulated and ... (minimum distance: 1,000 m) Ewes in the control group remained close to the pen where the rams were kept Intravaginal sponges containing 60 mg MAP (Syntex SA) were inserted in ewes of both groups on...

Ngày tải lên: 12/08/2014, 15:21