... genes involved in initiating hormone response in breast tumor cells might represent only 0.47% (89/18,912) of the genes in the human genome The list of putative ER target genes is presented in ... identify human and mouse genes and pinpoint their loci within the genome These annotations were chosen for their comprehensiveness, in terms of number of annotated genes, and their consistency ... Protein folding [0006457] M62403 IGFBP4† Insulin-like growth factor binding protein 12 Signal transduction [0007165] NM_001089 ABCA3† ATP-binding cassette, sub-family A (ABC1), member 12 ATP-binding...
Ngày tải lên: 14/08/2014, 14:21
... signaling pathway in lung epithelial cells, respectively, we investigated the possible involvement of TLR2 and TLR4 in NTHi-induced COX-2 expression in vitro by using HEK293 cells overexpressing ... TLR2 in epithelial cells in vitro and lung tissues of mice in vivo COX-2 up-regulation mediated by TLR2 in epithelial cells in vitro and lung tissues of mice in vivo A HEK293 cells overexpressing ... mechanisms underlying NTHi-induced PGE2 expression and in the pathological analysis of the role of PGE2 in NTHi infection based on the findings from present study will bring us novel insights into the...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: " RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1" pdf
... transcriptional repressor in CD4+ T cells [10] In these cells, RFX1 binds to target genes, including CD11a and CD70, and recruits the transcriptional co-repressors histone deacetylase (HDAC1) and DNA methyltransferase1 ... overexpression leads to overstimulation of IgG synthesis in B cells [9] The expression of both genes is also increased in T cells treated with the methylation inhibitor 5-azacitidine, suggesting ... restricts the expression of CD11a and CD70 and possibly other autoimmunerelated genes by maintaining a repressive chromatin state of their promoters The down-regulation of RFX1 CD4+ T cells in patients...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: "Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors" doc
... over-expressed in ERαtumors compared to ERα+ tumors in multiple breast tumor datasets We find in this study that genes involved in the myc network were coordinately expressed with Myc in both ER and ERα+ tumors ... proliferation genes more than ERα-positive tumors [15,32], and, therefore, similarities between cells proliferating in response to E2 in vitro and cells within tumors with a high proliferative index ... estrogen signaling in tumors reports In our analyses below involving human tumor profile data, we focused on our sets of in vitro E2-regulated genes, as we wanted to determine whether genes regulated...
Ngày tải lên: 14/08/2014, 16:21
Báo cáo "The role of color luminescence centers Mn, Cu, Co in the semicondutors with wide band gap ZnS, ZnO and their applications " pptx
... 181-187 When doping Cu, Mn in ZnS and Co in ZnO, the self-activated luminescence bands characterized by vacancies of zinc and oxygen are extinguished or their intensities decrease In PL spectra ... in argon and ZnO:Co (xCo = 2.10-2÷2.10-1 mol%) in air enviroment Annealing temperature and time were varied in range from 700oC to 1250oC and from 15 minutes to 36 hours [12-14] Nanocrystalline ... greater than that of the blue band As increasing the concentration of Cu, the intensity of the blue band decreases while the intensity of the green band increases and reaches to maximum at xCu...
Ngày tải lên: 22/03/2014, 11:20
báo cáo khoa học: " Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis" pps
... benign tumors (Figure 1B) Ang-2 was mainly expressed in tumor stroma and had similar expression pattern in malignant and benign tumors (Figure 1C, D) Maspin expression was predominantly located in ... staining for Ets-1, Ang-2 and Maspin in ovarian tumor tissues A: Ets-1 expression in ovarian moderately and poorly differentiated serous adenocarcinoma; B: Ets-1 expression in ovarian borderline ... roles in angiogenesis: Ang-1 and Ang-4 are agonist ligands for Tie2 and induce tyrosin phosphorylation of Tie2, while Ang-2 and Ang-3 are antagonist ligands They bind to Tie2 without inducing tyrosin...
Ngày tải lên: 10/08/2014, 10:21
Báo cáo y học: " T4 genes in the marine ecosystem: studies of the T4-like cyanophages and their role in marine ecology" doc
... hyroxymethyl cytosine or that they glycosylate their DNA In addition all of the r genes in T4 that are known to be involved in superinfection and lysis inhibition [45] are missing in cyanophage genomes, ... factor in T4 and is involved in the transcription of structural proteins [45] Homologues of the T4 -genes g33 and g45 which are also involved in late transcription in T4 are all found in Clokie ... in S-PM2, P-SSM4 and S-RMS4 speD encodes S-adenosylmethionine decarboxylase a key enzyme in the synthesis of the polyamines spermidine and spermine With polyamines implicated in the stabilising...
Ngày tải lên: 12/08/2014, 02:20
Common Errors and their Causes in Paragraph Writing Tasks by E.F.L. Second- year Students at Ha Hoa Tien University Các lỗi thường gặp và nguyên nhân mắc lỗi kh
... understanding why errors arise can assist in adjusting learning methods In term of teaching and designing syllabus, the study may help teachers in particular and educators in general to understand ... teachers and students in teaching and learning writing skill in particular and in improving their writing ability Objectives of the study The objectives of the study are: to investigate the types of ... to find out errors from the writing and the causes of each error in the interview result 2.3.2 Interviews 2.3.2.1 Interviewing After classifying the errors into categories, the researcher randomly...
Ngày tải lên: 28/03/2015, 09:37
Cloning and characterization of diamine oxidase and glutamate decarboxylase genes of mustard (brassica juncea) and their roles in shoot morphogenesis in vitro
... Lai Lai and Dr Yu Hao, for their help and encouragement during my staying in Singapore Their presence has created an enjoyable and productive working environment and made my staying in Singapore ... lines of AtGAD-AS, AtGAD-S and AttGAD plants 214 xvii Summary There is accumulating evidence showing that polyamines (PAs), including putrescine (Put), spermidine (Spd) and spermine (Spm), and ... the protein and DNA levels Several conserved regions including PLP and DFMO binding sites and a decarboxylase motif are present in all eukaryotic ADCs and ODCs (Poulin et al., 1992) ADC expression...
Ngày tải lên: 12/09/2015, 10:19
Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan
... grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the other stream The two streams flow together to be one stream and the sampling point St.4 is ... and periphery of the Seto Inland Sea The location of the research area and the distribution of the citrus groves in Matsuyama region are shown in Fig Matsuyama is situated in Shikoku Island in ... grove were investigated and their behaviors in the collecting reservoirs were discussed The main results obtained from the investigation are as follows: 1) Nitrogen concentration in grove soil...
Ngày tải lên: 05/09/2013, 10:17
A study on english food related idioms and proversbs and their equivalents in vietnamese
... confusing in defining, memorizing and using them To overcome these, some solutions are introduced in chapter III such as learning by heart, reading books, magazine, stories pictures and studying ... an insight into the similarities and differences in the use of language and images in English and Vietnamese idioms and proverbs II Some popular English idioms and proverbs relating to food and ... difference and similarities between English and Vietnamese idioms and proverbs Chapter 2: An investigation into English idioms and proverbs relating to food and their equivalence in Vietnamese...
Ngày tải lên: 11/12/2013, 23:48
A study on possessive determiners in english and their equivalents in vietnamese
... commit errors when learning and using possessive determiners in English Errors in using “a” and “the” in possessive determiners In process of studying “possessive determiners”, Vietnamese learners ... determiners use for feelings and thoughts to the person [81] Too many people blame their failings and their unhappiness on luck Scientists have taken a great interest in his ideas (Collin Cobuild, ... when using “possessive determiners” and suggested solutions Errors in word order of possessive determiners and the head noun Errors in using “a” and “the” in possessive determiners ...
Ngày tải lên: 11/12/2013, 23:53
Tài liệu Báo cáo khoa học: Direct identification of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS docx
... hydrophobins HFBIII of H jecorina and T longibrachiatum, and SRH1 and HFB1 of T atroviride, involving signal peptides, Kex2type processing, and C-terminal amino acid cleavage (Table 2) In addition, the recorded ... terminal amino acid residues of all six hydrophobins providing this single match A rapid means of identifying peaks corresponding to hydrophobins in MALDI-TOF mass spectra was elaborated, making ... mass peak was missing (Fig 3B) Deviating post-translational processing of hydrophobins in H jecorina strains To investigate strain diversity with respect to metabolite production and low-mass proteomics...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx
... metalloproteinases in vitro and eliminates production of avb3 integrin, a protein missing in normal melanocytes but often manufactured during the invasive phase [141] Hsp27 over expression in melanoma cells ... formation of huntingtin-containing inclusion bodies in Huntington’s disease encourages cell survival, whereas monomers and small inclusion bodies of huntingtin, a protein possessing abnormal polyQ ... aAcrystallin requires this domain [66] Attachment of R116C aA-crystallin to Hsp27 and aB-crystallin increases in comparison to wild type, while binding to cC-crystallin and bB2-crystallin decreases...
Ngày tải lên: 19/02/2014, 18:20
Tài liệu Báo cáo khoa học: Tachykinin-related peptide precursors in two cockroach species Molecular cloning and peptide expression in brain neurons and intestine docx
... from both brain and intestine in L maderae [14,15] The finding that N-terminally extended TKRPs are predominantly expressed only in the gut and not in the brain are in line with findings of enrichment ... in glomeruli of the tritocerebrum and in cells of the optical lobe Results Cloning of cockroach preprotachykinin cDNAs Using degenerated PCRs and RACE, we obtained full length preprotachykinin ... peptides, their receptors and invertebrate tachykinins: a review Zool Sci 20, 533–549 Pennefather, JN, Lecci A, Candenas ML, Patak E, Pinto FM & Maggi CA (2004) Tachykinins and tachykinin receptors:...
Ngày tải lên: 20/02/2014, 01:20
Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
... long chain fatty acids (Elovl3), type iodothyronine deiondinase (Dio2), homeobox C9 (Hoxc9), insulin-like growth factor binding protein (Igfbp3), dermatopontin (Dpt), and b-actin are showed in Table ... standard deviation inflammatory response and IR development, were examined in mice As shown in Figure 3, PM 2.5 exposure induced a marked increase in macrophage (F4/80+ cells) infiltration in ... reduced in both eWAT and iBAT in response to PM2.5 exposure Recent studies have implicated PM2.5 in increased adipose inflammation and insulin resistance [11,12], and epidemiological studies indicate...
Ngày tải lên: 06/03/2014, 19:20
Báo cáo khoa học: Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking potx
... other known cysteine-containing chitin-binding domains [14], such as plant chitin-binding proteins and horseshoe crab antimicrobial peptides with chitin-binding affinity [15–17] Rebers and Willis reported ... chitin-binding proteins in T tridentatus Amino acid compositions of high molecular mass (HMM) chitin-binding proteins HMM chitin-binding proteins resolved by 2D SDS ⁄ PAGE were categorized into ... with asterisks Numbers on the right indicate amino acid residue numbers and DE29 is involved in chitin binding In insects, cuticular proteins containing cysteine residues have not been reported,...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: "Towards Finding and Fixing Fragments: Using ML to Identify Non-Sentential Utterances and their Antecedents in Multi-Party Dialogue" ppt
... start with training a model using a baseline set of features, and then add each remaining feature individually, recording the gain (w.r.t the fmeasure (f (0.5), to be precise)), and choosing the best-performing ... said in the introduction, the main task we want to tackle is to align (certain kinds of) NSUs and their antecedents Now, what characterises this kind of NSU, and what are their antecedents? In ... Computing Meaning, volume Kluwer Raquel Fern´ ndez, Jonathan Ginzburg, and Shalom Lappin a 2004b Classifying ellipsis in dialogue: A machine learning approach In Proceedings of COLING 2004, Geneva,...
Ngày tải lên: 08/03/2014, 04:22
Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf
... as the metal binding event would be totally independent of the interactions involved in the enzyme–substrate complex The binding of MUG and Mg2+ are not independent, however, but instead are highly ... donor involved in the transferase Fig Diagram showing the thermodynamic equilibria and their dissociation constants involved in the binding of UDP-Glc, MUG and Mg2+ to TcdA Values shown in parentheses ... containing varying concentrations of UDP-Glc (0–145 mM) were studied The variable concentrations of UDP-Glc were obtained by starting with a stock solution containing all of the components including...
Ngày tải lên: 08/03/2014, 22:20