gap—quality of sponsor data used in calculating coverage gap discounts

... helpful in interpreting the findings from studies of the relationship between quality of life data and survival duration Quality of life data might be markers of the socio-economic status of cancer ... in many instances when one includes both physical functioning and performance status in the regression models, the likelihood of finding inconsistent results can be expected In other words, in ... that pain and appetite loss are independent determinants of overall survival One found that a 40-point increase in the pain subscale of the EORTC QLQ-C30 was associated with a 27% increase in the...

Ngày tải lên: 18/06/2014, 19:20

... al Data types Toxicity (in vivo and in vitro) and ecotoxicity (acute and chronic) data Ecotoxicity data Ecotoxicity (both acute and chronic) data Toxicity data (both in vivo and in vitro) Coverage ... out of 37 criteria The other three methods have each included less than half of the OECD reporting requirements in their list of criteria Some of the reporting requirements in the OECD guidelines ... approach can include checklists or even pre-defined evaluation criteria A major advantage of using a structured way of evaluating data is increased transparency and predictability of the risk...

Ngày tải lên: 21/06/2014, 03:20

... the problem of missing data in the field of HRQL and lung transplantation, and secondly to compare results from different methods of analysis in a data- set where missing data occur in order to ... the missing data problem is prevention Missingness of data caused by patient related factors is more unpreventable The missingness of data has two major undesirable effects First, if missingness ... investigation Irrespective of the reasons for, and the magnitude of the missing data problem, two methods of analyzing data are commonly performed in studies regarding the effects of lung transplantation...

Ngày tải lên: 12/08/2014, 18:22

... underlying the language teaching, and language teaching methods play a major role in determining the syllabus to be adopted Theory of learning also plays an important part in determining the kind of ... natural sequence of language learning i.e Listening, Speaking, Reading, Writing It ensures the active participation of learner in teaching Learning-process It is a natural way of learning the target ... teaching methods will be required/ used for teaching a language and teaching physical sciences Even in case of learning a language, the four main skills i.e listening, speaking, reading and writing...

Ngày tải lên: 10/04/2013, 10:37

... someone to continue or succeed Table 4.11: Verbs of Directing English Verbs of Directing Vietnamese Verbs of Directing In the process of saying these verbs of declaring are realized in the formula: ... political documents in English and Vietnamese; Verbs of saying are one of such verbs Therefore, a study of the linguistic features of saying verbs used in political documents in - To identify the ... classify the various meanings expressed by the saying verbs used in political documents in English and Vietnamese the Linguistic Features of Saying Verbs Used in Political SCOPE OF THE STUDY This study...

Ngày tải lên: 26/11/2013, 13:19

... the process of studying English, the researcher find difficult in understanding and translating meanings of term in general Because a lot of terms are used with connected meanings, others are the ... public employees working in the administrative and public-service agencies of the Ministry of Defense and the Ministry of Public Security) The reduction of indirect payroll in the State enterprises ... concepts of translation basing on the individual views And I have collected and studied some of them  Translation is the interpreting of the meaning of a text and the subsequent production of an...

Ngày tải lên: 11/12/2013, 23:55

... Silverstein proposed that the communicative force of culture works not only in representing aspects of reality, but also in connecting one context with another The concept of the indexical meaning of ... culture has methods of obtaining food and shelter Every culture has ways to protect itself against invaders It also has family relationships including forms of marriage and systems of kinship A culture ... not only the use of symbols that stand for beliefs, feelings, identities, events, it is also a way of pointing to, presupposing or bringing into the present context beliefs, feelings, identities,...

Ngày tải lên: 11/12/2013, 23:57

... Evaluation of ASTER data use in land use study in the Mekong Delta 29 discrimination capacity of ASTER data in land use mapping of such a dynamic area as the Mekong Delta in Vietnam Forest ... land use mapping of the studied area Instead of this, ASTER data provide a wide range of spectra and we assume that there exist some combinations of spectral bands in all three domains: VNIR, SWIR ... for which the combination is the most discriminative Due to the constraints of the spatial resolution of ASTER data in terms of parcel size in the studied area, the physical indexes such as NDVI...

Ngày tải lên: 13/02/2014, 12:20

... difficulties in obtaining EOC services in Gambia's main referral hospital Health service related inadequacies resulting from a "plethora of shortages" including lack of transfusion blood, shortage of essential ... hospitals still persists In our opinion this situation is self-reinforcing and driven by a combination of factors including the general fear of testing positive for HIV in a population where HIV ... important issues of care including: understanding users' experiences of health care, promoting cooperation, identifying problems and evaluating health care [38] The findings of this study show...

Ngày tải lên: 14/03/2014, 16:20

... building in the International Style, while to others it still holds onto characteristics of Streamline Moderne In can be considered to be in the International Style primarily because of its lack of ... compliments the interiors of his buildings One infamous piece of furniture from this period of time is his Barcelona chair It made its debut at the 1929 International Exhibition in Barcelona, Spain (Barcelona ... avenues of the International Style that were becoming very popular, and one of these was the furniture A principle of the Bauhaus was to cater to the development of contemporary housing The Bauhaus...

Ngày tải lên: 21/03/2014, 22:54

... the data Defining the categories and sub-categories Organisation of the data according to the categories and sub-categories Interpretation of the data While stating the views of teachers in the ... DynED Courses In the analysis of the data, it was seen that nearly all of the teachers had problems during or at the beginning of the process of DynED courses Some of the views of the teachers ... place in “interview method”; one of the qualitative data collection instruments Certain kinds of questions are prepared for use in all interviews of semi-structured interviews The questions prepared...

Ngày tải lên: 09/05/2014, 10:21

... knowledge of inspection and examination of education and training” to summarize some basic problems of education and training inspection {1} In 2006, Mr Ha TheTruyen wrote on “Examining-inspection ... the inspection system prevailing in Kenya The provision of feedback regarding findings of inspection (Kamuyu 2006), especially to schools inspected, should be ongoing during the process of inspection ... Education and Training and scientific issues of Education and Training; Have the capacity of analyzing, synthesizing, evaluating the situation of management in Education - Training at the provincial level,...

Ngày tải lên: 27/05/2014, 11:38

... steps of infection prevention: handwashing; use of protective barriers (gloves); treatment of instruments (decontamination, cleaning, sterilization, and high-level disinfection); and elimination of ... Figure Example 1of page of infection prevention in supervision checklist Example of page of infection prevention in supervision checklist The number of checked boxes in each column determines the total ... visits in intervention zones One of the most promising aspects of formative supervision is the participation of the community in evaluating and improving service quality Through their involvement in...

Ngày tải lên: 18/06/2014, 17:20

... the inadequacy of human resources (HR) in developing countries In the health sector in general, and in maternal health in particular, health care professionals are at the heart of the success of ... contexts Reducing the number of professionals for the gynaecological examination and increasing exposure to female personnel is preferred by most women, except in the case of certain interventions, ... flexibility in HR management and supervision, improvements in working conditions, institutionalization of a culture of accountability, application of financial incentives and better career planning [33,34,54,59,60]...

Ngày tải lên: 18/06/2014, 17:20

... advantage of this approach in our setting was the incorporation of the reminder data A subset of data containing only responders was utilised The data obtained by reminder was regarded as missing Initially ... those of the funding body References Conclusion The first step in the analysis of incomplete data should involve quantifying the extent of missingness, identifying which individuals have missing data ... than half of the data initially missing were recovered by the reminder system Identifying the missing data mechanism Hypothesis tests of MCAR Considering data from the first three time points, Little's...

Ngày tải lên: 18/06/2014, 19:20

... appointments of the day due to RLS? How often in the past weeks did you have trouble concentrating in the afternoon? How often in the past weeks did you have trouble concentrating in the evening? ... in TREAT RLS and TREAT RLS 2: 38 and 35 years, respectively Psychometric validation Missing data Missing data for TREAT RLS and are summarized in Table In TREAT RLS 1, missing data for each of ... effects of participating in a clinical trial, regardless of the specific nature of any intervention [26] The sensitivity of the RLSQoL to worsening RLS severity could not be fully evaluated in this...

Ngày tải lên: 20/06/2014, 15:20

... symptoms, including aches and pain Pain due to an underlying medical condition may induce or exacerbate depressive symptoms [2-8] However, the prevalence of pain in patients presenting with MDD, in ... groups in the Hassles Scale (Figure 1) and only Table 3: Pain location and intensity Location of pain head/neck no pain legs back arms generalized Brief Pain Inventory Intensity of current pain Controls ... nature of pain, severity of depression accounted only in part for pain intensity To further complicate matters, aggravating factors of pain such as fatigue and insomnia are also part of the syndromic...

Ngày tải lên: 20/06/2014, 15:20

... and clinically in epidemiological investigations as a quality of life instrument [16, 23-25] In contrast to most quality of life instruments for minors, which had originally been developed in English ... aim of this study is to quantify the level of agreement between self-reporting and proxy-assessment of children’s health-related quality of life using KINDL-R in a large population based study in ... case of boys than girls With increasing age of the children, the likelihood of parental overestimation of their child’s quality of life sinks for the ‘School’ dimension, whereas the likelihood of...

Ngày tải lên: 20/06/2014, 15:20

... simply maintaining gains and the QoL for some declining during the treatment period This is consistent with a chronic disease model of EDs Thus, caution is warranted in the interpretation of individual ... role in the current study, it would have probably biased findings in the direction of lower follow-up scores resulting in less responsiveness Even so, future research using clinical assessments of ... being tested in youth ages nine to 13 years Recent work using cognitive interviewing [34-36] resulted in refinements to six items The results reported herein relate to the first version A single...

Ngày tải lên: 20/06/2014, 16:20

... already used in bioengineering applications as for example 3, 4, 15 : model of neuron, bioelectrode model, model of respiratory mechanics, compartmental model of pharmacokinetics, and so forth, In ... numerical method and its application to solution of linear and nonlinear models of fractional order used in bioengineering applications For some of them, Matlab functions 15, 17, 20 were also published ... expressed by sum, a “short memory” principle can be used or without using “short memory” principle, we put v for all k in 2.22 Fractional-Order Models in Bioengineering Applications There are many...

Ngày tải lên: 21/06/2014, 05:20