function of radial glial cells

Ngày tải lên: 09/08/2014, 10:20

Ngày tải lên: 12/08/2014, 14:20

... of bilitranslocase controls the per- meability of HepG2 cells to bilirubin. Results and Discussion Expression of bilitranslocase in HepG2 cells HepG2 cells were used to study hepatic uptake of ... effects of the addi- tion of nicotinic acid, taurocholate and digoxin. Monolayers of HepG2 cells grown in 25-cm 2 flasks were preincubated for 1 h in the presence of 5 m M lactate. After removal of ... and ICG in HepG2 cells. In conclusion, this work shows that bilitranslocase is involved in the uptake of both bilirubin and BSP, but not of ICG, in HepG2 cells. The activity of bilitrans- locase...

Ngày tải lên: 07/03/2014, 21:20

... of transactivation function of the nuclear factors of activated T -cells Mi-Ock Lee 1, *, Hyo-Jin Kang 1, *, Young Mi Kim 1 , Ji-Hyun Oum 2 and Jungchan Park 2 1 Department of Bioscience and Biotechnology, ... interaction of F asL and its receptor, Fas [3–5]. Thus, the elimination of highly activated T -cells by the Fas/ FasL system is critical for the downregulation of immune responses, the homeostasis of lymphocytes, ... & R edondo, J .M. ( 1997) B lockade of T cell activation by dithiocarbamates involves novel mechanisms of inhibition of nuclear factor of activated T cells. Mol. Cell. Biol. 17, 6437–6447. 45....

Ngày tải lên: 24/03/2014, 03:21

... NMR spectrum of ELOA, showing up-field shifts of the resonance of bound oleic acid compared with those of free molecules. The 1 H NOESY spectrum of ELOA demonstrated the presence of cross-peaks between ... gain of new, beneficial function upon par- tial protein unfolding and fatty acid binding is a remarkable phenomenon, and may reflect a significant generic route of functional diversification of proteins ... understanding of the basic principles underlying protein self-assembly and acquisition of new functionality. HAMLET key features are related to the intrinsic properties of proteins to possess vary- ing functions...

Ngày tải lên: 29/03/2014, 21:20

... leukocyt es or by the responses of the resident cells of the CNS themselves. In support of the latter possibility, activate d glial cells are known to be capable of pro ducing toxic mediators that ... plaque assay of serial dilutions of HSV- 1 on Vero cells at 34°C. MHV-68 viral stocks were pre- pared by infecting monolayer cultures of BHK-21 cells (ATCC, CCL-10) at a low viral MOI of 0.1 PFU ... neuronal cell loss, either directly or via activation of resident/infiltrating myeloid cells. As such , the functional expression of DAI by glial cells may represent an important innate immune mechanism...

Ngày tải lên: 19/06/2014, 22:20

... the Function of Muscle Cells and Tissues – From Molecules to Humans 34 3.2. Calcium cycling in synthetic/proliferating VSMC The hallmark of synthetic status of VSMCs is a lack of functional ... subjects of articles. Part I includes articles dealing with basic aspects of function of skeletal and smooth muscle cells, and also melanocytes which have many properties common to those of smooth ... pathological aspects of cardiac and smooth muscle cell functions, while Part III consists of articles concerning factors influencing structure and function of cardiac and smooth muscle cells and tissues....

Ngày tải lên: 28/06/2014, 15:20

... Upregulation of miR-155 levels were also reported in human monocytes and mouse macrophages in response to LPS or interferon [7, 19]. Detailed analyses of the function of miR-155 in B cells revealed ... cell function [22]. Indeed latter it was shown that the levels of miR-181 correspond with the sensitivity of T cells to antigens [23]. In normal conditions, the successful transition of double ... repertoire because they negatively control the response of T cells to antigens. Increasing levels of miR-181 resulted in higher sensitivity of T cells to antigens, while the opposite was observed...

Ngày tải lên: 08/08/2014, 17:20

Ngày tải lên: 09/08/2014, 07:20

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 11/08/2014, 21:21

Ngày tải lên: 12/08/2014, 11:22

Ngày tải lên: 13/08/2014, 13:20

Ngày tải lên: 14/08/2014, 19:22

Ngày tải lên: 05/09/2013, 14:58

Ngày tải lên: 03/01/2014, 19:44

... recruitment of MOF to recently transcribed regions, especially at the 3Â ends of genes where H3-K36me3 is enriched [128]. In mammalian cells MOF also exists as part of a sepa- rate MOF–MSLv1 complex ... posi- tions of regulatory elements required for function in either T cells or mast cells. Shown below are the positions that nucleo- somes and GATA-2 occupy in unstimulated T cells and mast cells [85]. Active ... cells depletion of MOF, but not Tip60, results in reduced global levels of AcH4-K16 and defective DNA damage response [131]. In mouse embryos, MOF is essential for AcH4-K16, and loss of MOF results...

Ngày tải lên: 14/02/2014, 18:20

... absence of B lymphocytes and plasma cells and very low levels of immunoglobu- lins of all classes. Humoral immune responses are essentially nonexistent. T cells are not affected, but myeloid cells ... family of cytoplasmic enzymes that are important for several aspects of leu- kocyte biology. Both loss- and gain -of -function muta- tions in humans have been instrumental in our understanding of their ... total protein level, of BTK–SYK was less than that of ITK– SYK in 293T relative to COS7 cells. 293T cells express endogenous SYK, but we do not know whether this kinase influences the behavior of the fusion...

Ngày tải lên: 14/02/2014, 18:20

... full-length v-KIND; DKIND1, deletion of KIND1; DKIND2, deletion of KIND2; DKIND1 + 2, deletion of both KIND1 and KIND2; DRasN, deletion of RasN; DGEF, deletion of RasGEF; KIND1, KIND1 domain; KIND2, KIND2 ... pull- down assay of combinations of EGFP-fused KIND1 or KIND2 of v-KIND with GST-fused CD2-1-6-1 or CD2-1-6-2 of MAP2. We successfully detected a pull down for the combination of EGFP-KIND2 and GST-CD2-1-6-2, ... α -MAP2 kDa 50 37 25 CBB A B Fig. 2. Of all members of the KIND family of proteins, only KIND2 binds to MAP2. Pull-down assay (PD) of the endogenous MAP2 from cerebellar lysates of P21 mice (A, left) and...

Ngày tải lên: 14/02/2014, 19:20

... GIF expression in response to these different types of brain injury was often observed in glial cells accumulating at the degenerating area, where the glial scar was begin- ning to form. Intriguingly, ... regulating synaptic levels of zinc, as the GIF-deficient mice had a reduced content of Zn(II) within a number of brain regions [28]. ROS scavenging ability of GIF The coordination of redox-active metal ... important insights into the functional roles of this protein in the brain, and in particular its ability to inhibit neurite outgrowth (as described above). The functional role of GIF synthesis and secretion in...

Ngày tải lên: 16/02/2014, 15:20