Ngày tải lên: 12/08/2014, 11:22
... 1997) the authors investigated picture naming latencies, analysing whether the contour overlap of the stimuli was a better predictor of the performance than the living/ nonliving distinction within ... Common to these theories is the assumption that the organisation of conceptual knowledge is determined by representational constraints internal to the brain. However, the first class of theories ... authors themselves. A major emphasis has been on whether the results support one or another theory of the organisation of conceptual knowledge in the brain. In this effort, we have presented the...
Ngày tải lên: 03/04/2014, 12:07
scientific american - 1995 11 - guardian cells in the brain
... be residents of the brain tis- sue, not interlopers from the blood. Fi- nally, they examined the brain region containing the remains of the aÝected nerve cells. Analyses of tissue from many animals ... start, they focused on neu- rons whose cell bodies were located in the brain but whose axons terminated at muscles outside the brain. They in- jected a toxin into a site near the ends of the axons ... amounts of precipitation, of the magnitude experi- enced during the record El Ni–o winter of 1982Ð1983. One way of thinking about the impact of these earlier occur- rences, then, is as changes in the...
Ngày tải lên: 12/05/2014, 15:02
Báo cáo y học: " Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig" ppsx
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Mouse maps of gene expression in the brain" pot
Ngày tải lên: 14/08/2014, 07:21
Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... constitutes the initiating event in the process of lipotoxicity. Stearate has to be activated in order to be toxic The first enzyme involved in metabolism of FFAs after their uptake into liver cells is the ... group, indicating increased incorporation of palmitate (16:0) into the TAG pool only in the presence of oleate [18]. The above results raise two main questions: (a) what is the cause of TAG synthesis ... mammalian cells. This response can be divided in two phases according to the intensity and the duration of the stress. An initial adaptive response culminates in the temporary inhibition of protein...
Ngày tải lên: 14/02/2014, 22:20
Báo cáo khoa học: "A COMFUTATIONAL THEORY OF THE FUNCTION OF CLUE WORDS IN ARGUMENT UNDERSTANDING" potx
... to comment on the the function of clue words within analysis. The theory of clue interpretation gives insight into a known construction within sample dialogues; examining the computational ... but examine the relations between the use of anaphors and clues in the next section. Even w!thin the classification of connectives, there is a question of level of explicitness of the clues. ... the existing forms and possible categories. 258 A COMFUTATIONAL THEORY OF THE FUNCTION OF CLUE WORDS IN ARGUMENT UNDERSTANDING Robin Cohen Department of Computer Science University of...
Ngày tải lên: 08/03/2014, 18:20
Báo cáo khoa học: Alternative initiation of transcription of the humanpresenilin 1gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation ofpresenilin 1 pptx
... using the c oncen tration of protein in the extract as an internal standard. The activity of ()119/+178) PS1CAT in the pres- ence of the empty vector was taken as 100%. The values represented in the ... sequenced. Cloning of ERM Two independent clones containing the entire ERM cDNA were obtained by yeast one-hybrid screening of a human brain cDNA library from Clontech [26]. The cDNA was then inserted into ... domain. ERM contains two DNA binding inhibitory domains flanking the Ets domain: the central 87 amino acid inhibitory domain is poorly conserved a nd virtually specific to ERM, and the C-terminal...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 pot
... running in opposite direc- tions. The monomer association involves the ATP-using C-terminal domains interacting near the base of that side of the wedge outside; the N-terminal domains form the ... higher rates of phosphorylation of the E2-bound E1. Binding of a kinase dimer to a lipoyl domain containing a reduced lipoyl group fosters a further increase in kinase activity (PDK* state). Binding of ... domain and then rebinding to a second mobile lipoyl domain faster than releasing from the singly held state [21]. Each of the lipoyl domains of E2 is concentrated within the exterior of the complex...
Ngày tải lên: 17/03/2014, 09:20
Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc
... converting it to the reduced form (GSH) using an NADPH as the electron source. The function of GR in the male genital tract of the rat was examined by meas- uring its enzymatic activity and examining ... suggest that the GR system in Sertoli cells is involved in the supplementation of GSH to spermatoge nic cells in which high levels of cysteine are required for protamine synthesis. In turn, the genital tract, ... spermatogenic cells. DISCUSSION The findings in t his study show that GR is highly expressed in epithelial cells of the m ale genital tract, especially in the Fig. 4. Decrease in the levels of GR in testes...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo khoa học: Protective effects of endomorphins, endogenous opioid peptides in the brain, on human low density lipoprotein oxidation pdf
... Cu 2+ - induced LDL peroxidation is generally monitored by UV spectroscopy since the primary peroxidation Fig. 8. Inhibition of the increase in REM of LDL during the Cu 2+ -induced (A) or AAPH-initiated ... Therefore, protecting LDL from oxidation may be essential in the brain. The antioxidative effects of endomorphin 1 (EM1) and endomorphin 2 (EM2), endogenous opioid pep- tides in the brain, on LDL oxidation ... However, the great pharmacological disadvantages of many antioxi- dants are their very limited passage through the blood brain barrier [14]. Therefore, the existence of antioxidants in the brain protective...
Ngày tải lên: 23/03/2014, 10:21
Báo cáo khoa học: An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain docx
... concentrations of iron. The RT-PCR analysis in the present study shows that zebrafish RPE65 is predominantly expressed in the eye and, to a lesser extent, in the brain. Detection of RPE65 in the brain was ... 13cIMH. The results obtained showed that the RPE65 mRNA was predominantly expressed in the eye and at lower levels in the brain. By contrast, the 13cIMH mRNA was detected at high levels in the brain ... (2006) Calretinin immunoreactivity in the brain of the zebra- fish, Danio rerio: distribution and comparison with some neuropeptides and neurotransmitter-synthesizing enzymes. II. Midbrain, hindbrain,...
Ngày tải lên: 29/03/2014, 00:20
Pulmonary tuberculosis associated with increased number and percentage of natural killer and B cells in the peripheral blood pot
... percentage of CD3 - CD16 + CD56 + NK cells detected in patients with PTB in this study may therefore indicate the contribution of NK cells in the host immune response against MTB infection. The ... experiments in mice have unveiled the role of B cells in the optimal host response against MTB by increasing the infection inoculum (Vordermeier et al., 1996; Maglione et al., 2007). In addition the ... collected prior to initiation of anti-tuberculosis therapy. None of the patients included in the study had any evidence of suffering from diabetes, HIV infection or autoimmune diseases. The study was...
Ngày tải lên: 29/03/2014, 03:20
Báo cáo khoa học: Inactive forms of the catalytic subunit of protein kinase A are expressed in the brain of higher primates potx
... co-migrating with the shorter band seen in NT2-N cells is present in brain, but not in PBL (Fig. 3A, lanes 2 and 3). To examine whether the CbD4 variants were expressed in different parts of the brain ... together, these results suggest that CbD4 variants are not expressed in human PBL. Next, we searched for these splice variants in the brain of other species. Rhesus monkey brain and mouse brain ... 4. The fact that the CbD4 variants were expressed in NT2-N cells prompted us to investigate whether these variants are found in other human Cb-expressing tissues, such as brain [20] and immune cells...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: D-Amino acids in the brain: the biochemistry of brain serine racemase potx
... calcium binding are shown in orange and those involved in nucleotide binding are shown in red. Residues involved in the binding to the PLP moiety are shown in blue, whereas those involved in protein–protein ... if binding led to a translocation to the prox- imity of AMPARs in vivo (Fig. 3). Furthermore, the in uence of the other PDZ domains of GRIP was not investigated. Therefore, other proteins that ... subunit of AMPA receptors via PDZ4 ⁄ PDZ5, both PDZ domains working in concert to establish binding [27,28]. The finding of serine racemase interacting with the PDZ6 domain of GRIP and being activated...
Ngày tải lên: 30/03/2014, 04:20