function of glial cells in the brain
martin - the organisation of conceptual knowledge in the brain (psychology press, 2003)
... 1997) the authors investigated picture naming latencies, analysingwhether the contour overlap of the stimuli was a better predictor of the performance than the living/nonliving distinction within ... Common to thesetheories is the assumption that the organisation of conceptual knowledge is determined by representationalconstraints internal to the brain. However, the first class of theories ... authors themselves. Amajor emphasis has been on whether the results support one or another theory of the organisation of conceptual knowledge in the brain. In this effort, we have presented the...
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scientific american - 1995 11 - guardian cells in the brain
... be residents of the brain tis-sue, not interlopers from the blood. Fi-nally, they examined the brain regioncontaining the remains of the aÝectednerve cells. Analyses of tissue frommany animals ... start, they focused on neu-rons whose cell bodies were located in the brain but whose axons terminatedat muscles outside the brain. They in- jected a toxin into a site near the ends of the axons ... amounts of precipitation, of the magnitude experi-enced during the record El Ni–o winter of 1982Ð1983. One way of thinkingabout the impact of these earlier occur-rences, then, is as changes in the...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... constitutes the initiating event in the process of lipotoxicity.Stearate has to be activated in order to be toxic The first enzyme involved in metabolism of FFAs aftertheir uptake into liver cells is the ... group, indicatingincreased incorporation of palmitate (16:0) into the TAG pool only in the presence of oleate [18]. The above results raise two main questions: (a) whatis the cause of TAG synthesis ... mammalian cells. This responsecan be divided in two phases according to the intensityand the duration of the stress. An initial adaptiveresponse culminates in the temporary inhibition of protein...
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Báo cáo khoa học: "A COMFUTATIONAL THEORY OF THE FUNCTION OF CLUE WORDS IN ARGUMENT UNDERSTANDING" potx
... to comment on the the function of clue words within analysis. The theory of clue interpretation gives insight into a known construction within sample dialogues; examining the computational ... but examine the relations between the use of anaphors and clues in the next section. Even w!thin the classification of connectives, there is a question of level of explicitness of the clues. ... the existing forms and possible categories. 258 A COMFUTATIONAL THEORY OF THE FUNCTION OF CLUE WORDS IN ARGUMENT UNDERSTANDING Robin Cohen Department of Computer Science University of...
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Báo cáo khoa học: Alternative initiation of transcription of the humanpresenilin 1gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation ofpresenilin 1 pptx
... using the c oncen tration of protein in the extract as aninternal standard. The activity of ()119/+178) PS1CAT in the pres-ence of the empty vector was taken as 100%. The values represented in the ... sequenced.Cloning of ERMTwo independent clones containing the entire ERM cDNAwere obtained by yeast one-hybrid screening of a human brain cDNA library from Clontech [26]. The cDNA wasthen inserted into ... domain. ERM contains two DNA bindinginhibitory domains flanking the Ets domain: the central 87amino acid inhibitory domain is poorly conserved a ndvirtually specific to ERM, and the C-terminal...
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Báo cáo khoa học: Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 pot
... running in opposite direc-tions. The monomer association involves the ATP-usingC-terminal domains interacting near the base of that side of the wedge outside; the N-terminal domains form the ... higherrates of phosphorylation of the E2-bound E1. Binding of a kinasedimer to a lipoyl domain containing a reduced lipoyl group fosters afurther increase in kinase activity (PDK* state). Binding of ... domainand then rebinding to a second mobile lipoyl domain fasterthan releasing from the singly held state [21]. Each of the lipoyl domains of E2 is concentrated within the exterior of the complex...
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Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc
... converting it to the reduced form (GSH) usingan NADPH as the electron source. The function of GR in the male genital tract of the rat was examined by meas-uring its enzymatic activity and examining ... suggest that the GRsystem in Sertoli cells is involved in the supplementation of GSH to spermatoge nic cells in which high levels of cysteineare required for protamine synthesis. In turn, the genitaltract, ... spermatogenic cells. DISCUSSION The findings in t his study show that GR is highly expressed in epithelial cells of the m ale genital tract, especially in the Fig. 4. Decrease in the levels of GR in testes...
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Báo cáo khoa học: Protective effects of endomorphins, endogenous opioid peptides in the brain, on human low density lipoprotein oxidation pdf
... Cu2+-induced LDL peroxidation is generally monitored byUV spectroscopy since the primary peroxidationFig. 8. Inhibition of the increase in REM of LDL during the Cu2+-induced (A) or AAPH-initiated ... Therefore, protecting LDLfrom oxidation may be essential in the brain. The antioxidative effects of endomorphin 1 (EM1) and endomorphin 2 (EM2), endogenous opioid pep-tides in the brain, on LDL oxidation ... However, the great pharmacological disadvantages of many antioxi-dants are their very limited passage through the blood brain barrier [14]. Therefore, the existence of antioxidants in the brain protective...
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Báo cáo khoa học: An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain docx
... concentrations of iron. The RT-PCR analysis in the present study shows thatzebrafish RPE65 is predominantly expressed in the eyeand, to a lesser extent, in the brain. Detection of RPE65 in the brain was ... 13cIMH. The results obtainedshowed that the RPE65 mRNA was predominantlyexpressed in the eye and at lower levels in the brain. Bycontrast, the 13cIMH mRNA was detected at high levels in the brain ... (2006)Calretinin immunoreactivity in the brain of the zebra-fish, Danio rerio: distribution and comparison withsome neuropeptides and neurotransmitter-synthesizingenzymes. II. Midbrain, hindbrain,...
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Pulmonary tuberculosis associated with increased number and percentage of natural killer and B cells in the peripheral blood pot
... percentage of CD3-CD16+CD56+ NK cells detected in patients with PTB in this study may therefore indicate the contribution of NK cells in the host immune response against MTB infection. The ... experiments in mice have unveiled the role of B cells in the optimal host response against MTB by increasing the infection inoculum (Vordermeier et al., 1996; Maglione et al., 2007). In addition the ... collected prior to initiation of anti-tuberculosis therapy. None of the patients included in the study had any evidence of suffering from diabetes, HIV infection or autoimmune diseases. The study was...
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Báo cáo khoa học: Inactive forms of the catalytic subunit of protein kinase A are expressed in the brain of higher primates potx
... co-migrating with the shorterband seen in NT2-N cells is present in brain, but not in PBL (Fig. 3A, lanes 2 and 3). To examine whether the CbD4 variants were expressed in different parts of the brain ... together, these results suggest that CbD4variants are not expressed in human PBL.Next, we searched for these splice variants in the brain of other species. Rhesus monkey brain andmouse brain ... 4. The fact that the CbD4 variants were expressed in NT2-N cells prompted us to investigate whether thesevariants are found in other human Cb-expressingtissues, such as brain [20] and immune cells...
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Báo cáo khoa học: D-Amino acids in the brain: the biochemistry of brain serine racemase potx
... calcium binding areshown in orange and those involved in nucleotide binding are shown in red. Residues involved in the binding to the PLP moiety are shown in blue, whereas those involved in protein–protein ... if binding led to a translocation to the prox-imity of AMPARs in vivo (Fig. 3). Furthermore, the in uence of the other PDZ domains of GRIP was notinvestigated. Therefore, other proteins that ... subunit of AMPA receptors via PDZ4 ⁄ PDZ5, both PDZ domainsworking in concert to establish binding [27,28]. The finding of serine racemase interacting with the PDZ6domain of GRIP and being activated...
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Báo cáo sinh học: " Improvement of cardiac contractile function by peptide-based inhibition of NF-B in the utrophin/dystrophin-deficient murine model of muscular dystrophy" potx
... beyond the scope of this end-point driven study.DiscussionCardiac contractile dysfunction is one of the leadingcauses of death in DMD. Clinical treatment of thisdebilitating aspect of DMD ... from the tissueblocks and used for the following staining procedures.For viewing of gross histology, sections were fixed in 100% ethanol and then stained with hematoxylin andeosin using standard ... muscle disease caused by the absence of the dystrophin protein[1]. Although limb muscle weaknessand the loss of ambulation are us ually the initial clinicalsigns of the disease, patients with...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25