... suggesting that this MT isoform has different and distinct functions within the brain. Furthermore, the discovery and continued investigation of this brain-spe- cific MT isoform has led to intense interest ... intense interest in the roles of the entire MT family in the brain, with particular focus on the role of these proteins in the injured or neurodegenerative brain. Discovery of GIF AD is a neurodegenerative ... loss in the AD brain. Further investigation of the increased neurotrophic activity of the AD brain revealed that it correlated with the loss of a specific neuroinhibitory factor, rather than the...
Ngày tải lên: 16/02/2014, 15:20
... disease, thereby providing the missing data. The phenotype of XLA and the potential of BTK and ITK inhibitors The outcome of defective BTK signaling in humans has been described previously in detail ... residues directly involved in ligand binding, presumably abolishing the interaction with signaling partners. The remaining mutations alter amino acids located outside the ligand-binding pocket and ... one- third of all mutations in the BTK gene are missense and some of these reduce the stability of the protein. This is exemplified by mutations in the BTK motif of the Tec homology (TH) domain [18]....
Ngày tải lên: 14/02/2014, 18:20
Tài liệu ELECTRICAL /DATA CABLING WORKS IN THE BRANCH OF BANK OF INDIA, BHULLAR , LUDHIANA. doc
... schedules and the tender in original along with earnest money for Rs. 10,000/= in shape of demand draft in favour of Bank of India, shall be submitted in the office of Zonal Manager, Zonal office, ... shortcomings in the drawings or when they conflict with other works, or with each other. 26. The prospective contractor, on intimation of acceptance of tender must submit a progress network of the ... the date of opening of the tenders. 4. The time completion of work shall be essence of the contract, and shall be completed within 60 days only from the date of award of work 5. Offers...
Ngày tải lên: 16/02/2014, 11:20
Báo cáo hóa học: " Editorial Cross-Layer Design for the Physical, MAC, and Link Layer in Wireless Systems" doc
Ngày tải lên: 21/06/2014, 22:20
The Duality of Memory and Communication in the Implementation of a Multiprocessor Operating System
... when the data manager relinquishes that memory. If the data manager does not process and release the data within an adequate period of time, the data may then be paged out to the default pager. In ... acknowledgement. A data manager passes data for a memory object to the kernel by using the pager _data_ provided call. This call specifies the location of the data within the memory object, and includes the memory ... than in the inheritance case in that no sharing map is involved; an attempt to vm_write one mapping of the memory object would merely replace that mapping, rather than reflecting it in other...
Ngày tải lên: 12/09/2012, 15:05
Intelligent Software Agents on the Internet: an inventory of currently offered functionality in the information society & a prediction of (near-)future developments
... issue for the three layer model, as they ensure that (agents in) the individual layers can easily interface with (agents in) the other ones. Organisations such as the Internet Engineering Task ... 25 3.2.2.1 The Internet SoftBot 25 3.2.2.1 The Internet SoftBot 25 3.2.2.2 The Info Agent 27 3.2.2.2 The Info Agent 27 3.3 Summary 29 4 The Three Layer Model 31 4.1 Introduction 31 4.2 Definition ... two layer Internet, and an example will be given to give an impression of the new forms of functionality it can offer. 4.3.1 Middle layer (agent) functions " ;The fall in the cost of gathering...
Ngày tải lên: 08/10/2012, 15:22
Equivalence in the translation of vietnamese cultural words in the book “wandering through vietnamese culture” by huu ngoc
... non-lexicalization of the concepts, the lack of super ordinates of hyponyms etc. The main contribution of this paper is to draw out the main ways of dealing with the hurdles by investigating how an ... a basic “change of form”, by emphasizing the “intended in the text” as said “ Translation is rendering a written text into another language in the way the author intended in the text.” Hatim ... all the cultural words occurred in his book and put them into the order of the most common types of equivalence to the least common one. The data can be easily find in the table below: Type of...
Ngày tải lên: 07/11/2012, 14:31
Estimation of Proper Strain Rate in the CRSC Test Using a Artificial Neural Networks
... for use in training and testing the neural network. A large training data reduces the risk of under-sampling the nonlinear function, but increases the training time. To improve training, preprocessing ... learning data are used for training the ANN model, and the others are used for the comparison Data Collection Data Normalization Parametric Studies Training and Testing ANN Verify the reliance ... reliance of the ANN 631 between the predicted value and the measured value. The properties of the soil used for training of the MANN models are shown in Table 1. Table 1. Properties of the...
Ngày tải lên: 22/03/2013, 15:01
A study of kinematic vertical motions in the troposphere in Iraq
Ngày tải lên: 05/09/2013, 17:03
A study on oral presentation difficulties of second year english majors of phuong dong university in the speaking lessons and solutions
Ngày tải lên: 07/09/2013, 13:02
an inventory of currently offered functionality in the information society & a prediction of (near-)future developments
... third, intermediary layer to the structure of the Internet. This will enhance and improve the functionality of the Internet in many ways. Per layer, agents can be employed that can offer just the functionality ... Search engines are domain-independent in the way they treat gathered information and in the way they enable users to search in it 8 . Terms in gathered documents are lifted out of their context, ... 25 3.2.2.1 The Internet SoftBot 25 3.2.2.1 The Internet SoftBot 25 3.2.2.2 The Info Agent 27 3.2.2.2 The Info Agent 27 3.3 Summary 29 4 The Three Layer Model 31 4.1 Introduction 31 4.2 Definition...
Ngày tải lên: 26/10/2013, 17:15
Tài liệu Module 7- Data Link Layer CCNA Exploration 4.0 pptx
... consists of virtual connections between the nodes of a network independent of their physical layout. – These logical signal paths are defined by Data Link layer protocols. • The Data Link layer ... www.bkacad.com Connecting Upper Layer Services to the Media 11 • To support a wide variety of network functions, the Data Link layer is often divided into two sublayers: an upper sublayer and an lower sublayer. ... Data Link Layer Protocols- The Frame 31 • Remember that although there are many different Data Link layer protocols that describe Data Link layer frames, each frame...
Ngày tải lên: 22/12/2013, 13:17
Tài liệu Murray N. Rothbard - History Of Money And Banking In The United States (pdf) pptx
... speculators in accounting for the precipitous decline of the domestic purchasing power of the mark. Instead they direct his attention to the motives of the German Reichs- bank in expanding the money ... tell us is that in the past definite men or groups of men were valuing and acting in a definite way. Whether they will in the future value and act in the same way remains uncertain. All that can ... specific understanding be applied is not to diminish the importance of pure economic theory in the study of history. Indeed, as Mises points out, economics 14 A History of Money and Banking in the United...
Ngày tải lên: 17/01/2014, 02:20
A study on oral presentation difficulties of second year english majors of phuong dong university in the speaking lessons and solutions
... needed; the purpose or goal of the presentation; a preview of the main points or major ideas to be covered in the body. Next, comes the body of the presentation. The body is the central part of the ... rewriting it for the ear, (3) practising and revising it, and (4) organizing the visual aids. Once the learner has made an outline of the main points, write the presentation. The main purpose of ... due to their poor language knowledge, or in other words, either inadequate teaching or learning. Basing on the findings, the thesis is concluded with several suggestions for the learners, the teachers...
Ngày tải lên: 29/01/2014, 10:43
Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf
... a well-defined hyperintensity mass in the cervical area. The shape of the uterine cervix is distorted in the DWI (arrowhead). d On the ADC map the tumor is hypointense (arrow) and the normal ... imaging technique (SENSE factor of 2). Imaging time of DWI was 90 s for 20 slices. Detection of uterine malignancy The ADC values of uterine cancers are lower than of normal tissue. On the other ... with uterine leiomyomas and a bleeding cyst. a Axial T2-WI shows an area of hypointensity in the center of the cystic component (arrow). b On T1-WI with fat suppression the area in the cystic...
Ngày tải lên: 13/02/2014, 06:20
Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt
... exposed on the surface of the monomer, pointing toward FAD or its neigh- bouring monomer in the tetramer. By contrast, the side chain of the mutated residue (Val376) points toward the inside of the ... cDNA sequences using the RACE method in both strains revealed the presence of a single point mutation in 1337 nucleotides of BmIVD. In the sku mutant, the 1127th guanine from the start codon was ... acts in the third step of leucine degradation and the sku mutant accumulates branched-chain amino acids in haemolymph, this mutant may be useful in the investigation of unique branched-chain amino acid...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... of PKA in the mitochondrial targeting of CYP2E1 The role of PKA in mitochondrial targeting of CYP2E1 was investigated using two approaches. The first approach involved measuring the level of mito- chondrial ... microsomes requires the co- translational insertion of the newly synthesized protein into the microsomal membrane, where the N-terminal hydrophobic signal sequence of the protein interacts with a ... consistent with the model suggesting a transmembrane topology of CYPs with a single N-terminal membrane anchor and most of the remaining protein exposed to the cytosolic side [15,17,30,31]. The intramitochondrial...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf
... chemokines stimu- lated mainly by in ammatory cytokines, including IL-1b, TNF-a and IFN-c. (B) Chemokines expressed in the joint recruit leukocytes into the joints. In addition to functioning in ... examination of affected rheu- matoid joints reveals extensive RANTES ⁄ CCL5 expression in the synovial lining and sublining layers [22]. The expression of RANTES ⁄ CCL5 in cultured FLS increases in both ... regulated mainly by TNF-a. The role of chemokines in RA pathogenesis The chemokines listed above are implicated in RA pathogenesis via the recruitment and retention of leu- kocytes in the joints. In addition...
Ngày tải lên: 18/02/2014, 18:20
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